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Journal Articles

Pharmacokinetic (PK)-Guided Dosing of Hydroxyurea for Tanzanian Children with Sickle Cell Anemia

Luke R. Smart, Emmanuela Eusebio Ambrose, Mwesige Charles, Kathryn McElhinney, Teresa S. Latham, Susan E. Stuber, Russell E. Ware

Blood (2024) 144 (Supplement 1): 289.

https://doi.org/10.1182/blood-2024-208608

Published: 2024

Journal Articles

Hydroxyurea Decreases Transfusion Utilization in Ugandan Children with Sickle Cell Anemia: Main Results from the Alternative Dosing and Prevention of Transfusions (ADAPT) Trial

Alexandra Power-Hays, Ruth Namazzi, Charles Kato, Andrea Conroy, Heather Ann Hume, Chandy C. John, Robert Opoka, Susan E. Stuber, Adam C. Lane, Teresa S. Latham, Russell E. Ware

Blood (2024) 144 (Supplement 1): 546.

https://doi.org/10.1182/blood-2024-211666

Published: 2024

Journal Articles

Hydroxyurea Treatment Reduces Infection Rates in African Children with Sickle Cell Anemia

Thomas N. Williams, Teresa S. Latham, George A. Tomlinson, Peter Olupot-Olupot, Brigida Santos, Leon Tshilolo, Adam C. Lane, Banu Aygun, Susan E. Stuber, Luke R. Smart, Russell E. Ware

Blood (2024) 144 (Supplement 1): 545.

https://doi.org/10.1182/blood-2024-210347

Published: 2024

Journal Articles

Growth and Puberty in African Children with Sickle Cell Anemia Treated with Hydroxyurea

Philippe Backeljauw, George A. Tomlinson, Luke R. Smart, Leon Tshilolo, Thomas N. Williams, Brigida Santos, Peter Olupot-Olupot, Susan E. Stuber, Adam C. Lane, Teresa S. Latham, Russell E. Ware

Blood (2024) 144 (Supplement 1): 544.

https://doi.org/10.1182/blood-2024-205848

Published: 2024

Journal Articles

Hydroxyurea Pharmacokinetics in Children with Sickle Cell Anemia: Comparison of Global Cohorts

Alexandra Power-Hays, Kathryn E. McElhinney, Teresa S. Latham, Tom N. Williams, George Mochamah, Peter Olupot-Olupot, George Paasi, Marvin Ellsworth Reid, Angela Rankine-Mullings, Robert Opoka, Chandy C. John, Patrick T. McGann, Charles T. Quinn, Susan E. Stuber, Russell E. Ware

Blood (2024) 144 (Supplement 1): 542.

https://doi.org/10.1182/blood-2024-201577

Published: 2024

Journal Articles

Newborn Screening for Sickle Cell Disease in Sub-Saharan Africa: Initial Results of the ASH Consortium on Newborn Screening in Africa (CONSA) Program

Bernard Onyango Awuonda, Charles Kiyaga, Lulu Chirande, Patience Camille Franklin, Obiageli E Nnodu, Emmanuela Eusebio Ambrose, Livingstone Gayus Dogara, Catherine Mupela Chunda-Liyoka, Catherine I. Segbefia, Theresa Louise Coetzer, Russell E. Ware

Blood (2024) 144 (Supplement 1): 541.

https://doi.org/10.1182/blood-2024-204280

Published: 2024

Journal Articles

Building Capacity in Sub-Saharan Africa to Address Sickle Cell Disease: The Consortium on Newborn Screening in Africa (CONSA)

Charles Kiyaga, Emmanuela Eusebio Ambrose, Bernard Onyango Awuonda, Lulu Chirande, Catherine Mupela Chunda-Liyoka, Livingstone Gayus Dogara, Patience Camille Franklin, Obiageli E Nnodu, Catherine I. Segbefia, Russell E. Ware, Theresa Louise Coetzer

Blood (2024) 144 (Supplement 1): 520.

https://doi.org/10.1182/blood-2024-203142

Published: 2024

Journal Articles

Stroke Training, Research, and Education Toward Capacity with Hydroxyurea (STRETCH)

Teresa S. Latham, Katarzyna Czabanowska, Suzanne Babich, Faith Yego, Russell E. Ware

Blood (2024) 144 (Supplement 1): 2242.

https://doi.org/10.1182/blood-2024-208160

Published: 2024

Journal Articles

Low Rate of Red Blood Cell Alloimmunization Among Transfused Children with Sickle Cell Anemia in Malawi without Pre-Transfusion Screening or Antigen Matching

Kristina Prus, April Evans, Apatsa Matatiyo, Gugulethu Mapurisa, Memory Nonganonga, Timothy Mutafya, Kambe Banda, Meffa Misiri, Manley Kamija, Rizine R Mzikamanda, II, Kate D. Westmoreland, Russell E. Ware

Blood (2024) 144 (Supplement 1): 4032.

https://doi.org/10.1182/blood-2024-209161

Published: 2024

Journal Articles

Double-Blind, Placebo-Controlled Randomized Controlled Trial of Hydroxyurea for HbSC: Results of the Prospective Identification of Variables As Outcomes for Treatment (PIVOT) Trial

Blood (2024) 144 (Supplement 1): 3.

https://doi.org/10.1182/blood-2024-204408

Published: 2024

Journal Articles

Effects of Splenomegaly in Children with Sickle Cell Anemia Treated with Hydroxyurea: Secondary Analysis of the Sphere Trial

Emmanuela Eusebio Ambrose, George A. Tomlinson, Patrick S. Ngoya, Susan E. Stuber, Teresa S. Latham, Abel Nkono Makubi, Russell E. Ware, Luke R. Smart

Blood (2024) 144 (Supplement 1): 2495.

https://doi.org/10.1182/blood-2024-208408

Published: 2024

Journal Articles

RED Blood Cell Alloimmunization in Sickle Cell Anaemia Patients in Kilifi, Kenya

Sophie Uyoga, Michael Muteti, Johnstone Makale, George Mochamah, Russell E. Ware, Thomas N. Williams

Blood (2024) 144 (Supplement 1): 5602.

https://doi.org/10.1182/blood-2024-206754

Published: 2024

Journal Articles

Growth Curves for Children Living with Sickle Cell Anemia in Kilifi County, Kenya, Do Not Follow Who Curves for Normal Children

Thomas N. Williams, George Mochamah, Sophie Uyoga, Gideon Nyutu, Teresa S. Latham, Philippe Backeljauw, Russell E. Ware, George A. Tomlinson

Blood (2024) 144 (Supplement 1): 5315.

https://doi.org/10.1182/blood-2024-208843

Published: 2024

Journal Articles

Hydroxyurea reduces infections in children with sickle cell anemia in Uganda

Ruth Namazzi, Caitlin Bond, Andrea L. Conroy, Dibyadyuti Datta, Abner Tagoola, Michael J. Goings, Jeong Hoon Jang, Russell E. Ware, Robert Opoka, Chandy C. John

Blood (2024) 143 (14): 1425–1428.

https://doi.org/10.1182/blood.2023021575

Published: 2024

Includes: Supplemental data

Journal Articles

Pharmacokinetic-Guided Hydroxyurea to Reduce Transfusion Requirements in Ugandan Children with Sickle Cell Anemia: Baseline Data from the Alternative Dosing and Prevention of Transfusions (ADAPT) Trial

Alexandra Power-Hays, Ruth Namazzi, Charles Kato, Andrea Conroy, Heather Ann Hume, Chandy C. John, Susan E. Stuber, Adam C. Lane, Teresa S. Latham, Robert Opoka, Russell E. Ware

Blood (2023) 142 (Supplement 1): 1156.

https://doi.org/10.1182/blood-2023-181058

Published: 2023

Journal Articles

Effects of L-Glutamine on Biomarkers of Response in Sickle Cell Disease: A Pharmacokinetics-Pharmacodynamics Analysis

Alina Sadaf, Min Dong, Jennifer Korpik, Amanda Pfeiffer, Theodosia A. Kalfa, Teresa S. Latham, Alexander A. Vinks, Russell E. Ware, Charles T. Quinn

Blood (2023) 142 (Supplement 1): 1145.

https://doi.org/10.1182/blood-2023-180312

Published: 2023

Journal Articles

Hydroxyurea Dose Optimization Is Safe and Improves Outcomes for Children with Sickle Cell Anemia Living in Sub-Saharan Africa: The Reach Experience

Banu Aygun, Adam C. Lane, Luke R. Smart, Leon Tshilolo, Thomas N. Williams, Peter Olupot-Olupot, Brigida Santos, Susan E. Stuber, George A. Tomlinson, Teresa S. Latham, Russell E. Ware

Blood (2023) 142 (Supplement 1): 6.

https://doi.org/10.1182/blood-2023-172919

Published: 2023

Journal Articles

Hydroxyurea Improves Intelligence Quotient Scores in Children with Sickle Cell Anemia and Elevated Transcranial Doppler Velocity

Angela E Rankine-Mullings, Deanne Soares, Karen Aldred, Susan Chang-Lopez, Margaret Elizabeth Wisdom-Phipps, William Schultz, Teresa S. Latham, Susan E. Stuber, Patrice Jackson, Russell E. Ware, Marvin Ellsworth Reid

Blood (2023) 142 (Supplement 1): 797.

https://doi.org/10.1182/blood-2023-188160

Published: 2023

Journal Articles

A Novel, Rapid, and Accurate Quantitative Hydroxyurea Assay

Kathryn McElhinney, Luke R. Smart, Thad Alan Howard, Alexandra Power-Hays, Russell E. Ware

Blood (2023) 142 (Supplement 1): 2530.

https://doi.org/10.1182/blood-2023-190100

Published: 2023

Journal Articles

Prospective Identification of Variables As Outcomes for Treatment (PIVOT): A Phase II Clinical Trial of Hydroxyurea for Children and Adults with HbSC Disease

Catherine I. Segbefia, Luke R. Smart, Susan E. Stuber, Priscilla Ekpale, Kwesi N. Amissah-Arthur, Klenam Dzefi-Tettey, Enoch Mensah, Adam C. Lane, Diana Dwuma-Badu, Teresa S. Latham, Yvonne Dei-Adomakoh, Russell E. Ware

Blood (2023) 142 (Supplement 1): 3877.

https://doi.org/10.1182/blood-2023-190351

Published: 2023

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Pharmacokinetic (PK)-Guided Dosing of Hydroxyurea for Tanzanian Children with Sickle Cell Anemia

Hydroxyurea Decreases Transfusion Utilization in Ugandan Children with Sickle Cell Anemia: Main Results from the Alternative Dosing and Prevention of Transfusions (ADAPT) Trial

Hydroxyurea Treatment Reduces Infection Rates in African Children with Sickle Cell Anemia

Growth and Puberty in African Children with Sickle Cell Anemia Treated with Hydroxyurea

Hydroxyurea Pharmacokinetics in Children with Sickle Cell Anemia: Comparison of Global Cohorts

Newborn Screening for Sickle Cell Disease in Sub-Saharan Africa: Initial Results of the ASH Consortium on Newborn Screening in Africa (CONSA) Program

Building Capacity in Sub-Saharan Africa to Address Sickle Cell Disease: The Consortium on Newborn Screening in Africa (CONSA)

Stroke Training, Research, and Education Toward Capacity with Hydroxyurea (STRETCH)

Low Rate of Red Blood Cell Alloimmunization Among Transfused Children with Sickle Cell Anemia in Malawi without Pre-Transfusion Screening or Antigen Matching

Double-Blind, Placebo-Controlled Randomized Controlled Trial of Hydroxyurea for HbSC: Results of the Prospective Identification of Variables As Outcomes for Treatment (PIVOT) Trial

Effects of Splenomegaly in Children with Sickle Cell Anemia Treated with Hydroxyurea: Secondary Analysis of the Sphere Trial

RED Blood Cell Alloimmunization in Sickle Cell Anaemia Patients in Kilifi, Kenya

Growth Curves for Children Living with Sickle Cell Anemia in Kilifi County, Kenya, Do Not Follow Who Curves for Normal Children

Hydroxyurea reduces infections in children with sickle cell anemia in Uganda

Pharmacokinetic-Guided Hydroxyurea to Reduce Transfusion Requirements in Ugandan Children with Sickle Cell Anemia: Baseline Data from the Alternative Dosing and Prevention of Transfusions (ADAPT) Trial

Effects of L-Glutamine on Biomarkers of Response in Sickle Cell Disease: A Pharmacokinetics-Pharmacodynamics Analysis

Hydroxyurea Dose Optimization Is Safe and Improves Outcomes for Children with Sickle Cell Anemia Living in Sub-Saharan Africa: The Reach Experience

Hydroxyurea Improves Intelligence Quotient Scores in Children with Sickle Cell Anemia and Elevated Transcranial Doppler Velocity

A Novel, Rapid, and Accurate Quantitative Hydroxyurea Assay

Prospective Identification of Variables As Outcomes for Treatment (PIVOT): A Phase II Clinical Trial of Hydroxyurea for Children and Adults with HbSC Disease

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