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Rosa Bacchetta
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Journal Articles

T-allo10 Immunotherapy Results in Enhanced Early Immune Reconstitution and Reduced GvHD with Excellent Clinical Outcomes Post Αβ-Depleted HSCT in Pediatric and Young Adult Hematologic Malignancy Patients

Free
Alice Bertaina, Rosa Bacchetta, Alma-Martina Cepika, David C Shyr, Giulia Barbarito, Linda Oppizzi, Pauline Chen, Gopin Saini, Jennifer Lee, Karen Kristovich, Rajni Agarwal, Orly Klein, Kathryn Melsop, Keri Tate, Matthew Porteus, Maria Grazia Roncarolo
Journal: Blood
Blood (2024) 144 (Supplement 1): 3525.
https://doi.org/10.1182/blood-2024-194276
Published: 2024
Journal Articles

Fatal autoimmunity in mice reconstituted with human hematopoietic stem cells encoding defective FOXP3

Free
Jeremy A. Goettel, Subhabrata Biswas, Willem S. Lexmond, Ada Yeste, Laura Passerini, Bonny Patel, Siyoung Yang, Jiusong Sun, Jodie Ouahed, Dror S. Shouval, Katelyn J. McCann, Bruce H. Horwitz, Diane Mathis, Edgar L. Milford, Luigi D. Notarangelo, Maria-Grazia Roncarolo, Edda Fiebiger, Wayne A. Marasco, Rosa Bacchetta, Francisco J. Quintana, Sung-Yun Pai, Christoph Klein, Aleixo M. Muise, Scott B. Snapper
Journal: Blood
Blood (2015) 125 (25): 3886–3895.
https://doi.org/10.1182/blood-2014-12-618363
Published: 2015
Includes: Supplemental data
Journal Articles

IL-21 signalling via STAT3 primes human naïve B cells to respond to IL-2 to enhance their differentiation into plasmablasts

Free
Lucinda J. Berglund, Danielle T. Avery, Cindy S. Ma, Leen Moens, Elissa K. Deenick, Jacinta Bustamante, Stephanie Boisson-Dupuis, Melanie Wong, Stephen Adelstein, Peter D. Arkwright, Rosa Bacchetta, Liliana Bezrodnik, Harjit Dadi, Chaim M. Roifman, David A. Fulcher, John B. Ziegler, Joanne M. Smart, Masao Kobayashi, Capucine Picard, Anne Durandy, Matthew C. Cook, Jean-Laurent Casanova, Gulbu Uzel, Stuart G. Tangye
Journal: Blood
Blood (2013) 122 (24): 3940–3950.
https://doi.org/10.1182/blood-2013-06-506865
Published: 2013
Journal Articles

T-Cell-Mediated Suppression: From Bench to Bedside

Free
Maria Grazia Roncarolo, MD, Manuela Battaglia, PhD, Rosa Bacchetta, MD, Megan Levings, PhD, Silvia Gregori, PhD
Journal: Blood
Blood (2013) 122 (21): SCI-37.
https://doi.org/10.1182/blood.V122.21.SCI-37.SCI-37
Published: 2013
Journal Articles

Accumulation of peripheral autoreactive B cells in the absence of functional human regulatory T cells

Free
Tuure Kinnunen, Nicolas Chamberlain, Henner Morbach, Jinyoung Choi, Sangtaek Kim, Joseph Craft, Lloyd Mayer, Caterina Cancrini, Laura Passerini, Rosa Bacchetta, Hans D. Ochs, Troy R. Torgerson, Eric Meffre
Journal: Blood
Blood (2013) 121 (9): 1595–1603.
https://doi.org/10.1182/blood-2012-09-457465
Published: 2013
Includes: Supplemental data
Journal Articles

A novel function for FOXP3 in humans: intrinsic regulation of conventional T cells

Free
Alicia N. McMurchy, Jana Gillies, Maria Concetta Gizzi, Michela Riba, Jose Manuel Garcia-Manteiga, Davide Cittaro, Dejan Lazarevic, Sara Di Nunzio, Ignazio S. Piras, Alessandro Bulfone, Maria Grazia Roncarolo, Elia Stupka, Rosa Bacchetta, Megan K. Levings
Journal: Blood
Blood (2013) 121 (8): 1265–1275.
https://doi.org/10.1182/blood-2012-05-431023
Published: 2013
Includes: Supplemental data
Journal Articles

Interleukin-10 Anergized Donor T Cell Infusion Improves Immune Reconstitution without Severe Graft-Versus-Host-Disease After Haploidentical Hematopoietic Stem Cell Transplantation.

Free
Rosa Bacchetta, MD, Claudia Sartirana, Barbarella Lucarelli, Patrick Miqueu, Maria Teresa Lupo Stanghellini, MD, Raffaella Greco, M.D., Andrea Velardi, Franco Aversa, Massimo F Martelli, Silvia Gregori, Elisabetta Zappone, Katharina Fleischhauer, Massimo Bernardi, MD, Jacopo Peccatori, MD, Fabio Ciceri, MD, Maria Grazia Roncarolo, MD, Prof.
Journal: Blood
Blood (2009) 114 (22): 45.
https://doi.org/10.1182/blood.V114.22.45.45
Published: 2009
Journal Articles

Wild-type FOXP3 is selectively active in CD4 + CD25 hi regulatory T cells of healthy female carriers of different FOXP3 mutations

Free
Brief Report
Sara Di Nunzio, Massimiliano Cecconi, Laura Passerini, Alicia N. McMurchy, Udo Baron, Ivana Turbachova, Silvia Vignola, Erica Valencic, Alberto Tommasini, Anne Junker, Giantonio Cazzola, Sven Olek, Megan K. Levings, Lucia Perroni, Maria Grazia Roncarolo, Rosa Bacchetta
Journal: Blood
Blood (2009) 114 (19): 4138–4141.
https://doi.org/10.1182/blood-2009-04-214593
Published: 2009
Includes: Supplemental data
Journal Articles

Selective engraftment of donor CD4 + 25 high FOXP3-positive T cells in IPEX syndrome after nonmyeloablative hematopoietic stem cell transplantation

Free
Markus G. Seidel, Gerhard Fritsch, Thomas Lion, Birgit Jürgens, Andreas Heitger, Rosa Bacchetta, Anita Lawitschka, Christina Peters, Helmut Gadner, Susanne Matthes-Martin
Journal: Blood
Blood (2009) 113 (22): 5689–5691.
https://doi.org/10.1182/blood-2009-02-206359
Published: 2009
Journal Articles

Temporal, quantitative, and functional characteristics of single-KIR–positive alloreactive natural killer cell recovery account for impaired graft-versus-leukemia activity after haploidentical hematopoietic stem cell transplantation

Free
Luca Vago, Barbara Forno, Maria Pia Sormani, Roberto Crocchiolo, Elisabetta Zino, Simona Di Terlizzi, Maria Teresa Lupo Stanghellini, Benedetta Mazzi, Serena K. Perna, Attilio Bondanza, Derek Middleton, Alessio Palini, Massimo Bernardi, Rosa Bacchetta, Jacopo Peccatori, Silvano Rossini, Maria Grazia Roncarolo, Claudio Bordignon, Chiara Bonini, Fabio Ciceri, Katharina Fleischhauer
Journal: Blood
Blood (2008) 112 (8): 3488–3499.
https://doi.org/10.1182/blood-2007-07-103325
Published: 2008