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Journal Articles

Addition of thiotepa to a busulphan based conditioning regimen does not improve survival in patients allografted for acute myeloid leukaemia and myelodysplasia: Results of the UK impact cosi trial

Blood (2025) 146 (Supplement 1): 110.

https://doi.org/10.1182/blood-2025-110

Published: 2025

Journal Articles

In Vivo transfer of CD4+ T cells reshapes CD8+ T cell differentiation trajectory in humans

Andrew McIntyre, Maria Cuadrado, Joshua Hughes, Elisa Armbrecht, Pedro Santos e Sousa, Gordon Beattie, Imran Uddin, Pawan Dhami, Alex McLatchie, Heli Vaikkinen, PROT Study Group, Persephone Borrow, Ronjon Chakraverty

Blood (2025) 146 (Supplement 1): 260.

https://doi.org/10.1182/blood-2025-260

Published: 2025

Journal Articles

T cell resistance to glucocorticoids in graft-versus-host disease

Andrew McIntyre, Lisanne Schoutens, Elisa Armbrecht, Andrew Gravett, Nicolas Sanschagrin, Callum Wright, Matthew Collin, Ronjon Chakraverty

Blood (2025) 146 (Supplement 1): 2316.

https://doi.org/10.1182/blood-2025-2316

Published: 2025

Journal Articles

B-lineage acute lymphoblastic leukaemia disrupts a LepR+ bone marrow stromal niche which is critical for CAR-T cell persistence

Aideen O'Neill, Constandina Pospori, Elisa Armbrecht, Louis Peters, Paul Maciocia, Cristina Lo Celso, Ronjon Chakraverty

Blood (2025) 146 (Supplement 1): 4118.

https://doi.org/10.1182/blood-2025-4118

Published: 2025

Journal Articles

Incorporation of 8Gy total body irradiation into reduced intensity conditioning does not improve allogeneic transplant outcomes for high-risk adult acute lymphoblastic leukemia: Results from the randomised prospective phase 2 UK multicentre ALL-RIC impact study

Blood (2025) 146 (Supplement 1): 374.

https://doi.org/10.1182/blood-2025-374

Published: 2025

Journal Articles

Enhancement of mTORC1 Activity in Engineered Therapeutic CD4+ T Cells Amplifies Tumour Infiltration but Impairs Cytotoxicity

Francesca Emily Sillito, Angelika Holler, Aideen T O'Neill, Lauren A Callender, Sian M Henson, Hans Stauss, Ronjon Chakraverty

Blood (2024) 144 (Supplement 1): 7196.

https://doi.org/10.1182/blood-2024-207047

Published: 2024

Journal Articles

The Role of the Bone Marrow Immune Niche in Preventing Relapse in Adult B-ALL Following Reduced Intensity Conditioning Allogeneic HSCT

Hermione E Allen, Andrew McIntyre, Jesus Gutierrez-Abril, Amy A Kirkwood, Daniel Leongamornlert, Rodothea Amerikanou, Emily A Cutler, Aditi Dey, Richard Burt, Ronjon Chakraverty, Adele Kay Fielding

Blood (2024) 144 (Supplement 1): 1454.

https://doi.org/10.1182/blood-2024-205516

Published: 2024

Journal Articles

Ruxolitinib in Patients With Chronic Graft-Versus-Host Disease: 3-Year Final Analysis of Efficacy and Safety From the Phase III REACH3 Study

Robert Zeiser, Domenico Russo, Ron Ram, Shahrukh K Hashmi, Ronjon Chakraverty, Jan Moritz Middeke, Maurizio Musso, Sebastian Giebel, Ant Uzay, Peter Langmuir, Nada Hamad, Xuechan Li, Maanasa Gowda, Tommaso Stefanelli, Stephanie J. Lee, Takanori Teshima, Franco Locatelli

Blood (2023) 142 (Supplement 1): 654.

https://doi.org/10.1182/blood-2023-172590

Published: 2023

Journal Articles

The UK Impact Transplant Trials Network: An Effective National Strategy to Accelerate the Delivery of Randomized Trials in Stem Cell Transplantation

Charles Craddock, David Marks, Victoria Potter, Wendy A Ingram, Rebecca Collings, Eleni Tholouli, Rachel Protheroe, Hugh Allen, Alex Ross, Dawn Farrar, Shamyla Siddique, Rebecca Bishop, Ronjon Chakraverty

Blood (2023) 142 (Supplement 1): 5097.

https://doi.org/10.1182/blood-2023-188490

Published: 2023

Journal Articles

Allogeneic stem cell transplantation compared to conservative management in adults with inborn errors of immunity

Blood (2023) 141 (1): 60–71.

https://doi.org/10.1182/blood.2022015482

Published: 2023

Includes: Supplemental data

Journal Articles

Graft-Versus-Host Disease Induces Immune Dysregulation through Irreversible Damage to Specialized Immune-Interacting Fibroblastic Stromal Cells in Secondary Lymphoid Organs

Leolene Carrington, Shovik Bandyopadhyay, Katlyn Lederer, Samantha Kelly, Ashley Vanderbeck, Gloria Jih, Frederick Allen, Daniela Gómez Atria, Anneka Allman, Eric Perkey, Kai Tan, Norbert Pardi, Burkhard Ludewig, Ronjon Chakraverty, Ivan Maillard

Blood (2022) 140 (Supplement 1): 7334–7335.

https://doi.org/10.1182/blood-2022-167650

Published: 2022

Journal Articles

Graft Versus Leukaemia (GvL): Identification & Characterisation of Alloreactive Antigens and Cognate T Cell Responses in Acute Myeloid Leukemia

Connor Sweeney, Gerda Mickute, Kinam Gupta, Marlen Metzner, Batchimeg Usukhbayar, Maria Chiara Barbanti, Gavinda Sangha, Ronjon Chakraverty, Persephone Borrow, Nicola Ternette, Ane Ogbe, Maria Aggelakopoulou, Paresh Vyas

Blood (2022) 140 (Supplement 1): 1576–1578.

https://doi.org/10.1182/blood-2022-166918

Published: 2022

Journal Articles

Graft-versus-host disease: a disorder of tissue regeneration and repair

Ronjon Chakraverty, Takanori Teshima

Blood (2021) 138 (18): 1657–1665.

https://doi.org/10.1182/blood.2021011867

Published: 2021

Journal Articles

Ruxolitinib (RUX) Vs Best Available Therapy (BAT) in Patients with Steroid-Refractory/Steroid-Dependent Chronic Graft-Vs-Host Disease (cGVHD): Primary Findings from the Phase 3, Randomized REACH3 Study

Robert Zeiser, PhD, Nicola Polverelli, MD PhD, Ron Ram, MD, Shahrukh K. Hashmi, MDMPH, Ronjon Chakraverty, BMBS, PhD, Mary E. D. Flowers, MD, Fitzroy Dawkins, MD, Norbert Hollaender, MD, Maanasa Gowda, PharmD, Tommaso Stefanelli, MD, Stephanie J. Lee, MDMPH, Takanori Teshima, MD, Franco Locatelli, MD PhD

Blood (2020) 136 (Supplement 1): 22–24.

https://doi.org/10.1182/blood-2020-137694

Published: 2020

Journal Articles

A Phase I Study Evaluating the Safety and Persistence of Allorestricted WT1-TCR Gene Modified Autologous T Cells in Patients with High-Risk Myeloid Malignancies Unsuitable for Allogeneic Stem Cell Transplantation

Blood (2019) 134 (Supplement_1): 1367.

https://doi.org/10.1182/blood-2019-128044

Published: 2019

Journal Articles

Predictors of Response in Patients Receiving CD34-Selected Stem Cell Infusions without Conditioning to Correct Graft Failure Following Allogeneic Stem Cell Transplantation

Maria del Mar Cuadrado, MBBS, Mark W. Lowdell, BSc, MSc, PhD FRCPath, Stuart Ings, Michael J. Watts, PhD, Richard Szydlo, PhD, Chloe Anthias, MD, J. Alejandro Madrigal, MDPhDDSc,FRCP,FRCPath, Panagiotis Kottaridis, FRCPath,PhDMSc, Ben Carpenter, PhD, Rachael Hough, MD BMBS, FRCP, FRCPath, Karl Peggs, MBBChir, Kirsty Thomson, PhD, Emma Morris, FRCPath, MA, MBBChir, PhD MRCP, Ronjon Chakraverty, BMBS, PhD

Blood (2018) 132 (Supplement 1): 204.

https://doi.org/10.1182/blood-2018-99-115054

Published: 2018

Journal Articles

Successful outcome following allogeneic hematopoietic stem cell transplantation in adults with primary immunodeficiency

Blood (2018) 131 (8): 917–931.

https://doi.org/10.1182/blood-2017-09-807487

Published: 2018

Journal Articles

Remission Status at Transplantation and Treatment History Determine the Survival Chances of Patients after Allogeneic Hematopoietic Stem Cell Transplantation for Chronic Lymphocytic Leukemia Who Had Received Pre-Treatment with Idelalisib: A Report from the EBMT Chronic Malignancies Working Party

Blood (2017) 130 (Supplement 1): 4576.

https://doi.org/10.1182/blood.V130.Suppl_1.4576.4576

Published: 2017

Journal Articles

Bone Marrow Infiltrating T-Cell Signatures Following Allo-HCT for Adult Acute Lymphoblastic Leukaemia Differentiate between Patients in Continuous CR and Those with Persistent Minimal Residual Disease or Relapse

Dina Ahmed Said Aly Okasha, MBBS, MSc, Amy A Kirkwood, Krisztina Zuborne Alapi, MSc, Rachel J Mitchell, MSc, Pedro Santos e Sousa, MD PhD, Daniel Leongamornlert, PhD, Elli Papaemmanuil, PhD, David Marks, MD PhD, Ronjon Chakraverty, BMBS, PhD, Adele K Fielding, MBBS,PhDFRCP,FRCPath

Blood (2017) 130 (Supplement 1): 1317.

https://doi.org/10.1182/blood.V130.Suppl_1.1317.1317

Published: 2017

Journal Articles

Gene therapy for Wiskott-Aldrich syndrome in a severely affected adult

Blood (2017) 130 (11): 1327–1335.

https://doi.org/10.1182/blood-2017-04-777136

Published: 2017

Includes: Supplemental data

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Addition of thiotepa to a busulphan based conditioning regimen does not improve survival in patients allografted for acute myeloid leukaemia and myelodysplasia: Results of the UK impact cosi trial

In Vivo transfer of CD4+ T cells reshapes CD8+ T cell differentiation trajectory in humans

T cell resistance to glucocorticoids in graft-versus-host disease

B-lineage acute lymphoblastic leukaemia disrupts a LepR+ bone marrow stromal niche which is critical for CAR-T cell persistence

Incorporation of 8Gy total body irradiation into reduced intensity conditioning does not improve allogeneic transplant outcomes for high-risk adult acute lymphoblastic leukemia: Results from the randomised prospective phase 2 UK multicentre ALL-RIC impact study

Enhancement of mTORC1 Activity in Engineered Therapeutic CD4+ T Cells Amplifies Tumour Infiltration but Impairs Cytotoxicity

The Role of the Bone Marrow Immune Niche in Preventing Relapse in Adult B-ALL Following Reduced Intensity Conditioning Allogeneic HSCT

Ruxolitinib in Patients With Chronic Graft-Versus-Host Disease: 3-Year Final Analysis of Efficacy and Safety From the Phase III REACH3 Study

The UK Impact Transplant Trials Network: An Effective National Strategy to Accelerate the Delivery of Randomized Trials in Stem Cell Transplantation

Allogeneic stem cell transplantation compared to conservative management in adults with inborn errors of immunity

Graft-Versus-Host Disease Induces Immune Dysregulation through Irreversible Damage to Specialized Immune-Interacting Fibroblastic Stromal Cells in Secondary Lymphoid Organs

Graft Versus Leukaemia (GvL): Identification & Characterisation of Alloreactive Antigens and Cognate T Cell Responses in Acute Myeloid Leukemia

Graft-versus-host disease: a disorder of tissue regeneration and repair

Ruxolitinib (RUX) Vs Best Available Therapy (BAT) in Patients with Steroid-Refractory/Steroid-Dependent Chronic Graft-Vs-Host Disease (cGVHD): Primary Findings from the Phase 3, Randomized REACH3 Study

A Phase I Study Evaluating the Safety and Persistence of Allorestricted WT1-TCR Gene Modified Autologous T Cells in Patients with High-Risk Myeloid Malignancies Unsuitable for Allogeneic Stem Cell Transplantation

Predictors of Response in Patients Receiving CD34-Selected Stem Cell Infusions without Conditioning to Correct Graft Failure Following Allogeneic Stem Cell Transplantation

Successful outcome following allogeneic hematopoietic stem cell transplantation in adults with primary immunodeficiency

Remission Status at Transplantation and Treatment History Determine the Survival Chances of Patients after Allogeneic Hematopoietic Stem Cell Transplantation for Chronic Lymphocytic Leukemia Who Had Received Pre-Treatment with Idelalisib: A Report from the EBMT Chronic Malignancies Working Party

Bone Marrow Infiltrating T-Cell Signatures Following Allo-HCT for Adult Acute Lymphoblastic Leukaemia Differentiate between Patients in Continuous CR and Those with Persistent Minimal Residual Disease or Relapse

Gene therapy for Wiskott-Aldrich syndrome in a severely affected adult

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