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Romain Guieze
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Journal Articles

A phase 3, randomized, open-label, multicenter study of sonrotoclax (BGB-11417) plus anti-CD20 antibody therapies vs venetoclax plus rituximab in patients with relapsed/refractory chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL-RR1/CELESTIAL-RRCLL)

Free
Othman Al-Sawaf, Sandra Robrecht, Matthew S Davids, Mary Ann Anderson, Romain Guieze, Valeria Buccheri, Celso Arrais-Rodrigues, Francesc Bosch Albareda, Ruth Clifford, Michael Doubek, Krzysztof Jamroziak, Arnon Kater, Mattias Mattsson, Carsten Niemann, Miguel Pavlovsky, Lydia Scarfo, Renata Walewska, Peng Liu, Ki-Seong Eom, Karl Kreuzer, Eugen Tausch, Christof Schneider, Stephan Stilgenbauer, Kirsten Fischer, Michael Hallek, Kenneth Wu, Marcus Lefebure, Wei Ding, Remus Vezan, Barbara Eichhorst
Journal: Blood
Blood (2025) 146 (Supplement 1): 2137.
https://doi.org/10.1182/blood-2025-2137
Published: 2025
Journal Articles

Time-limited acalabrutinib monotherapy in frail patients with previously untreated chronic lymphocytic leukemia: Primary endpoint analysis of the randomized STAIR trial.

Free
Romain Guieze, Emmanuelle Ferrant, Fatiha Merabet, Lysiane Molina, Driss Chaoui, Pierre Feugier, Therese Aurran-Schleinitz, Safia Chebrek, Hugo Gonzalez, Aline Clavert, Marlene Ochmann, Kamel Laribi, Anne-Sophie Michallet, Vincent Levy, Benedicte Hivert, Caroline Dartigeas, Laurence Simon, Damien Roos Weil, Anne Quinquenel, Anne Violaine Doncker, Julie Gay, Antoine Bonnet, Marie-Sarah Dilhuydy, Emmanuelle Tchernonog, Bernard Drenou, Sophie de Guibert, Laurence Sanhes, Stephane Lepretre, Olivier Tournilhac, Florence Nguyen-Khac, valerie rouille, Marie Poinsignon, Cabarrou Bastien, Loic Ysebaert
Journal: Blood
Blood (2025) 146 (Supplement 1): 684.
https://doi.org/10.1182/blood-2025-684
Published: 2025
Journal Articles

Updated efficacy and safety results of the Bruton tyrosine kinase degrader BGB-16673 in patients with relapsed/refractory indolent non-Hodgkin lymphoma from the ongoing phase 1 CaDAnCe-101 study

Free
Romain Guieze, Annamaria Frustaci, Chan Cheah, John Seymour, Dok Hyun Yoon, Irina Mocanu, Eric Mou, Pier Luigi Zinzani, Amitkumar Mehta, Constantine Tam, Judith Trotman, Yanan Zhang, Linlin Xu, Kunthel By, Amber Lussier, Shannon Fabre, Daniel Persky, Ranjana Advani
Journal: Blood
Blood (2025) 146 (Supplement 1): 3584.
https://doi.org/10.1182/blood-2025-3584
Published: 2025
Journal Articles

Randomized study of high-dose cytarabine with or without dexamethasone as post-remission therapy in younger adults with newly diagnosed AML – the french backbone intergroup (BIG)-1 study on behalf of the filo, ALFA, and SFGM-TC study groups

Free
Christian Recher, Marie-Anne Hospital, Thibaut Leguay, Martin Carre, Corentin Orvain, Caroline Bonmati, Emmanuel Raffoux, Celestine Simand, Romain Guieze, Jamilé Frayfer, Juliette Lambert, Sylvain Chantepie, Marc Bernard, Pierre Peterlin, Magda Alexis, Pascal Turlure, Cecile Pautas, Sarah Bertoli, Ludovic Gabellier, Edouard Forcade, Nicolas Duployez, Isabelle Luquet, Dominique Penther, Karine Celli-Lebras, Ariane Mineur, Claude Gardin, Norbert Ifrah, Norbert Vey, Regis Peffault De Latour, Pierre-Yves Dumas, Eric Delabesse, Claude Preudhomme, Jean-François Hamel, Herve Dombret, Arnaud Pigneux, Hunault-Berger Mathilde, Stephane De Botton
Journal: Blood
Blood (2025) 146 (Supplement 1): 881.
https://doi.org/10.1182/blood-2025-881
Published: 2025
Journal Articles

MCL1 copy number gain is a recurrent mark of venetoclax resistance in patients with chronic lymphocytic leukemia

Free
Carolyne Croizier, Manon Garcia, Stéphanie Poulain, Loic Ysebaert, Sylvain Carras, Damien Roos Weil, Anne Quinquenel, Anne-Sophie Michallet, Emmanuelle Tchernonog, Pierre Morel, Adrien Chauchet, Pierre Feugier, Nataliya Dmytruk, Morgane Nudel Ortmans, Elise Chapiro, Grégory Lazarian, Olivier Tournilhac, Marc Berger, Bruno Pereira, Ludivine Paris, Nathan Papon, Inès Ramos, Lauren Veronese, Romain Guieze
Journal: Blood
Blood (2025) 146 (Supplement 1): 3875.
https://doi.org/10.1182/blood-2025-3875
Published: 2025
Journal Articles

Validation of the FL/IL6 score, a new dynamic cytokine-based risk-model in adults with acute myeloid leukemia, a prospective multicentre filo study.

Free
Pierre Peterlin, Joëlle Gaschet, Sarah Bertoli, Marc Bernard, Martin Carre, Pierre Yves Dumas, Chama Mokeddem, Amine Belhabri, Anne Banos, Caroline Bonmati, Emmanuelle Tavernier, Gaëlle Guillerm, Sarah Bonnet, Justine Decroocq, Alain Saad, Mario Ojeda-Uribe, Romain Guieze, Raja Prince-Eladnani, Alice Garnier, Arnaud Pigneux, Christian Recher, Marie-Anne Vibet, Patrice Chevallier
Journal: Blood
Blood (2025) 146 (Supplement 1): 5247.
https://doi.org/10.1182/blood-2025-5247
Published: 2025
Journal Articles

Preliminary efficacy and safety of the Bruton tyrosine kinase degrader BGB-16673 in patients with relapsed/refractory Richter transformation: Results from the ongoing phase 1 CaDAnCe-101 study

Free
Meghan Thompson, Annamaria Frustaci, John Seymour, John Allan, Paolo Ghia, Olivier Dumas, Franck Morschhauser, Martin Dreyling, Stephan Stilgenbauer, Inhye Ahn, Romain Guieze, Yanan Zhang, Linlin Xu, Kunthel By, Shannon Fabre, Daniel Persky, Amit Agarwal, Carlo Visco
Journal: Blood
Blood (2025) 146 (Supplement 1): 3895.
https://doi.org/10.1182/blood-2025-3895
Published: 2025
Journal Articles

Frequency and impact of FLT3-ITD microclones in younger AML patients

Free
Nicolas Duployez, Romane Joudinaud, Augustin Boudry, Mathilde Hunault, Emmanuelle Tavernier, Cecile Pautas, Sarah Bertoli, Suzanne Tavitian, Emmanuel Raffoux, Marie-Anne Hospital, Raja Prince-Eladnani, Mael Heiblig, Sylvain Chantepie, Martin Carre, Pierre Peterlin, Maria Pilar Gallego Hernanz, Romain Guieze, Célestine Simand, Pascal Turlure, Anne Huynh, Emilie Lemasle, Ludovic Gabellier, Juliette Lambert, Felipe Suarez, Samy Chraibi, Laurence Sanhes, Karine Celli-Lebras, Ariane Mineur, Claude Gardin, Norbert Ifrah, Norbert Vey, Regis Peffault De Latour, Isabelle Luquet, Dominique Penther, Raphael Itzykson, Eric Delabesse, Jean-François Hamel, Stephane De Botton, Arnaud Pigneux, Herve Dombret, Christian Recher, Claude Preudhomme, Pierre-Yves Dumas
Journal: Blood
Blood (2025) 146 (Supplement 1): 456.
https://doi.org/10.1182/blood-2025-456
Published: 2025
Journal Articles

Valemetostat monotherapy in patients with relapsed or refractory B-cell lymphoma: Final results of the Phase 2 valym study from the lysa

Free
Emmanuel Bachy, Fontanet Bijou, Bohrane Slama, Romain Guieze, Keiko Nakajima, Gandhi Damaj, Gian Matteo Pica, Nadine Morineau, Charles Herbaux, Roch Houot, Bernard Drenou, François Lemonnier, Marlene Ochmann, Antoine Bonnet, Pierre Sujobert, Gaetan Vanstraelen, Marc Andre, Delphine Pranger, Marguerite Fournier, Sylvia Snauwaert, Thomas Gastinne, Fabrice Jardin, Julie Gay, Alexandra Traverse Glehen, Katell Le Du, Jean Marc Schiano De Colella, Franck Morschhauser
Journal: Blood
Blood (2025) 146 (Supplement 1): 1797.
https://doi.org/10.1182/blood-2025-1797
Published: 2025
Journal Articles

Impact of midostaurin in younger AML patients intensively treated with high-dose anthracycline

Free
Pierre-Yves Dumas, Mathieu Leclerc, Mathilde Hunault, Emmanuelle Tavernier, Cecile Pautas, Sarah Bertoli, Thibaut Leguay, Suzanne Tavitian, Emmanuel Raffoux, Marie-Anne Hospital, Sylvain Chantepie, Mael Heiblig, Martin Carre, Pierre Peterlin, Maria Pilar Gallego Hernanz, Romain Guieze, Célestine Simand, Pascal Turlure, Anne Huynh, Emilie Lemasle, Ludovic Gabellier, Juliette Lambert, Delphine Lebon, Madalina Uzunov, Jean-Valère Malfuson, Thomas Cluzeau, Samy Chraibi, Laurence Sanhes, Karine Celli-Lebras, Ariane Mineur, Claude Gardin, Norbert Ifrah, Norbert Vey, Regis Peffault De Latour, Isabelle Luquet, Dominique Penther, Eric Delabesse, Jean-François Hamel, Raphael Itzykson, Claude Preudhomme, Stephane De Botton, Nicolas Duployez, Arnaud Pigneux, Herve Dombret, Christian Recher
Journal: Blood
Blood (2025) 146 (Supplement 1): 1682.
https://doi.org/10.1182/blood-2025-1682
Published: 2025
Journal Articles

Induction chemotherapy with a single anthracycline-containing cycle in younger adults with newly diagnosed AML – the french backbone intergroup (BIG)-1 study on behalf of the filo, ALFA, and SFGM-TC study groups

Free
Christian Recher, Cecile Pautas, Sarah Bertoli, Pierre-Yves Dumas, Emmanuel Raffoux, Marie-Anne Hospital, Raja Prince-Eladnani, Mael Heiblig, Martin Carre, Sylvain Chantepie, Pierre Peterlin, Maria Pilar Gallego Hernanz, Juliette Lambert, Corentin Orvain, Romain Guieze, Pascal Turlure, Celestine Simand, Emilie Lemasle, Chantal Himberlin, Caroline Bonmati, Jean Valère Malfuson, Delphine Lebon, Thomas Cluzeau, Emmanuelle Tavernier, Jean-Baptiste Micol, Karine Celli-Lebras, Ariane Mineur, Claude Gardin, Norbert Ifrah, Norbert Vey, Regis Peffault De Latour, Anne Huynh, Thibaut Leguay, Isabelle Luquet, Dominique Penther, Nicolas Duployez, Eric Delabesse, Claude Preudhomme, Herve Dombret, Jean-François Hamel, Arnaud Pigneux, Hunault-Berger Mathilde
Journal: Blood
Blood (2025) 146 (Supplement 1): 43.
https://doi.org/10.1182/blood-2025-43
Published: 2025
Journal Articles

How far can ibrutinib resonate?

Free
Clinical Trials & Observations
Romain Guièze
Journal: Blood
Blood (2025) 146 (18): 2147–2148.
https://doi.org/10.1182/blood.2025030421
Published: 2025
Journal Articles

Valemetostat Monotherapy in Patients with Relapsed or Refractory Large B-Cell Lymphoma: Primary Results of the Phase 2 Valym Study from the Lysa

Free
Emmanuel Bachy, Bernard Drenou, Fabrice Jardin, Keiko Nakajima, Katell Le Du, Gandhi Damaj, Fontanet Bijou, Borhane Slama, Gian Matteo Pica, Gaetan Vanstraelen, Charles Herbaux, Roch Houot, Francois Lemonnier, Julie Gay, Pierre Sujobert, Marguerite Fournier, Marlene Ochmann, Romain Guieze, Jorge Zeron, Alexandra Traverse-Glehen, Jean Marc Schiano De Colella, Franck Morschhauser
Journal: Blood
Blood (2024) 144 (Supplement 1): 4479.
https://doi.org/10.1182/blood-2024-193960
Published: 2024
Journal Articles

Minimal Residual Disease-Guided Combination of Ibrutinib and Venetoclax Compared to FCR in Untreated Patients with CLL of Intermediate Risk : Final Results of the Eradic Trial from the Filo Group

Free
Anne Sophie Michallet, Remi Letestu, Magali Legarff, Stéphane Morisset, Therese Aurran-Schleinitz, Kamel Laribi, Vincent Levy, Laurence Simon, Damien Roos Weil, Marie Sarah Dilhuydy, Cecile Tomowiak, Caroline Dartigeas, Romain Guieze, Olivier Tournilhac, Emmanuelle Ferrant, Sophie De Guibert, Pierre Feugier, Fatiha Merabet, Stéphane Lepretre, Philippe Carassou, Julie Gay, Benedicte Hivert, Luc-Matthieu Fornecker, Jehan Dupuis, Lysiane Molina, Bruno Villemagne, Guillaume Cartron, Bernard Drenou, Omar Benbrahim, Xavier Cahu, Florence Nguyen Khac, Valerie Rouillé, Loic Ysebaert, Anne Quinquenel
Journal: Blood
Blood (2024) 144 (Supplement 1): 584.
https://doi.org/10.1182/blood-2024-194593
Published: 2024
Journal Articles

Outcomes with Venetoclax-Based Treatment in Patients with Covalent Bruton Tyrosine Kinase Inhibitor (cBTKi)-Treated, Chemotherapy-Naïve Chronic Lymphocytic Leukemia (CLL): An International Retrospective Study

Free
Paul J. Hampel, Kari G. Rabe, Romain Guieze, Yucai Wang, Emmanuelle Ferrant, Saad S. Kenderian, Marie Sarah Dilhuydy, Eli Muchtar, Anne-Sophie Michallet, Jose F. Leis, Luca Inchiappa, Mazie Tsang, Aline Clavert, Talal Hilal, Stephane Lepretre, Ricardo D. Parrondo, Emmanuelle Tchernonog, Amber Koehler, Lin Wang, Susan M. Schwager, Susan L. Slager, Neil E. Kay, Luc-Matthieu Fornecker, Sameer A. Parikh, Loic Ysebaert
Journal: Blood
Blood (2024) 144 (Supplement 1): 1856.
https://doi.org/10.1182/blood-2024-198200
Published: 2024
Journal Articles

Outcomes of CLL Patients Exposed to Venetoclax+/-R after Ibrutinib in France: The Resist Retrospective Study from the Filo-CLL Group

Free
Loic Ysebaert, Emmanuelle Ferrant, Marie Sarah Dilhuydy, Anne-Sophie Michallet, Luca Inchiappa, Romain Guieze, Emmanuelle Tchernonog, Ana Cavillon, Marie Christine Bene, Luc-Matthieu Fornecker
Journal: Blood
Blood (2023) 142 (Supplement 1): 3273.
https://doi.org/10.1182/blood-2023-180696
Published: 2023
Journal Articles

Real-World Outcomes Using Front-Line Midostaurine in Combination with Intensive Chemotherapy for Patients Aged ≥ 60 Years Old with FLT3 Mutated Acute Myeloid Leukemia

Free
Gaspar Aspas Requena, Pierre Yves Dumas, Rebeca Rodriguez Veiga, Sarah Bertoli, Cristina Gil, Celestine Simand, Fernando Jesús Ramos-Ortega, Pierre Peterlin, Josefina Serrano, Rudy Birsen, Teresa Bernal Del Castillo, Emmanuelle Tavernier, Mar Tormo, Martin Carre, Maria Jose Garcia, Adrien Contejean, Rosalia Riaza Grau, Corentin Orvain, Jose Antonio Pérez-Simón, Esther Perez Santaolla, Lauren Veronese, Beatriz De Rueda Ciller, Eric Delabesse, Antonio Gutiérrez, Ariane Mineur, Adolfo De La Fuente Burguera, Romain Guieze, Arnaud Pigneux, Pau Montesinos, Christian Recher, David Matínez-Cuadrón
Journal: Blood
Blood (2023) 142 (Supplement 1): 2864.
https://doi.org/10.1182/blood-2023-190128
Published: 2023
Journal Articles

Minimal Residual Disease-Guided Combination of Ibrutinib and Venetoclax Compared to FCR in Untreated Patients with CLL of Intermediate Risk : Interim Results of MRD Kinetics in the Eradic Trial from the Filo Group

Free
Anne-Sophie Michallet, Anne Quinquenel, Remi Letestu, Tavernier Magali, Stéphane Morisset, Therese Aurran, Kamel Laribi, Florence Cymbalista, Vincent Levy, Laurence Simon, Damien Roos Weil, Veronique Leblond, Marie Sarah Dilhuydy, Cecile Tomowiak, Caroline Dartigeas, Romain Guieze, Olivier Tournilhac, Emmanuelle Ferrant, Sophie De Guibert, Pierre Feugier, Fatiha Merabet, Stéphane Lepretre, Philippe Carassou, Julie Gay, Benedicte Hivert, Luc Matthieu Fornecker, Jehan Dupuis, Lysiane Molina, Bruno Villemagne, Guillaume Cartron, Bernard Drenou, Béatrice Mahé, Omar Benbrahim, Xavier Cahu, Christelle Portois, Loic Ysebaert, Florence Nguyen Khac, Valerie Rouillé, Alain Jacques Delmer
Journal: Blood
Blood (2023) 142 (Supplement 1): 3268.
https://doi.org/10.1182/blood-2023-173341
Published: 2023
Journal Articles

CPX-351 in Patients with Newly Diagnosed Post Myeloproliferative Neoplasms Acute Myeloid Leukemia

Free
Sylvain Garciaz, Amine Belhabri, Romain Guieze, Laure Goursaud, Pierre Peterlin, Marie-Pierre Ledoux, Hunault-Berger Mathilde, Safia Chebrek, Jean-Baptiste Robin, Arnaud Pigneux, Sarah Bonnet, Caroline Bonmati, Sarah Bertoli, Thorsten Braun, Sylvain Chantepie, Mathieu Meunier, Mael Heiblig, Thomas Cluzeau, Eric Jourdan, Alban Villate, Christian Recher, Norbert Vey, Jerome Rey
Journal: Blood
Blood (2023) 142 (Supplement 1): 2917.
https://doi.org/10.1182/blood-2023-184591
Published: 2023
Journal Articles

Tazemetostat in Combination with R-CHOP in Patients with High-Risk, Frontline Follicular Lymphoma (Epi-RCHOP): A Phase II Study from the Lysa

Free
Loic Ysebaert, Francois Lemonnier, Gabriel Brisou, Olivier Casasnovas, Gian Matteo Pica, Emmanuel Bachy, Ludovic Fouillet, Julie Abraham, Stephanie Guidez, Marc André, Guillaume Cartron, Romain Guieze, Sylvain Carras, Benoit Tessoulin, Roch Houot, Bohrane Slama, Christophe Bonnet, Luc-Matthieu Fornecker, Marie-Helene Delfau, Clementine Sarkozy, Camille Laurent, Vincent Ribrag, Franck Morschhauser
Journal: Blood
Blood (2023) 142 (Supplement 1): 297.
https://doi.org/10.1182/blood-2023-185057
Published: 2023