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Journal Articles

Allogeneic Peripheral Blood Stem Cell Transplantation for Bone Marrow Failure Syndromes Using CD34 + -Selected Progenitor Cells Co-Infused with a Reduced Number of Non-Mobilized T-Cells

Georg Aue, Yazan Migdady, Yimo Wang, Jennifer Wilder, Brian Wells, Rosa Nadal Rios, Joseph A. Clara, Robert Reger, Kristen Gunn, Melissa Spencer, Jennifer Farren, Patricia Prince, Reem A Shalabi, Steven Highfill, David F. Stroncek, Xin Tian, Richard W. Childs

Blood (2022) 140 (Supplement 1): 7576–7577.

https://doi.org/10.1182/blood-2022-169922

Published: 2022

Journal Articles

CRISPR Gene-Editing of Chemokine Receptors As a Novel Strategy to Redirect NK Cell Trafficking In Vivo

Emily R. Levy, PhD, Joseph Clara, MD, David Allan, PhD, Robert Reger, MS, Richard W. Childs, MD

Blood (2020) 136 (Supplement 1): 3.

https://doi.org/10.1182/blood-2020-141408

Published: 2020

Journal Articles

Cell Density of NK Cells during Ex Vivo Expansion Impacts NK Cell Surface TRAIL Expression

Joseph A. Clara, MD, Robert Reger, MS, Mala Chakraborty, PhD, Steven L Highfill, PhD, Jianjian Jin, PhD, David F. Stroncek, MD, Richard W. Childs, MD

Blood (2020) 136 (Supplement 1): 5–6.

https://doi.org/10.1182/blood-2020-141487

Published: 2020

Journal Articles

Rapid Engraftment, Immune Recovery, and Resolution of Transfusion Dependence in Treatment-Refractory Severe Aplastic Anemia Following Transplantation with Ex Vivo Expanded Umbilical Cord Blood (Omidubicel)

Mohamed Samour, MD, Georg Aue, MD PhD, Joseph Clara, Jennifer Wilder, Robert Reger, MS, Rosa Nadal Rios, MD, Kate Stringaris, MD PhD, Brian Wells, Lisa Cook, Kristen Gunn, Reem A Shalabi, PharmD, Josef Rivero, Patricia Prince, David F. Stroncek, MD, Willy A. Flegel, MD, Xin Tian, PhD, Richard W. Childs, MD

Blood (2020) 136 (Supplement 1): 37–38.

https://doi.org/10.1182/blood-2020-137771

Published: 2020

Journal Articles

Effect of Cyclosporine Inhalation Solution (CIS) on Lung Function and Inflammatory Biomarkers in Patients with Hematopoietic Stem Cell Transplant (HSCT) Associated Bronchiolitis Obliterans Syndrome (BOS)

Janhavi Athale, MD, Nicole J Gormley, MD, Robert Reger, MS, Sara Alsaaty, MS, Debra Reda, BSN, Tatyana Worthy, MSN, Ankit Saxena, Ph. D, Xin Tian, Ph. D, Richard W. Childs, MD, Anthony F Suffredini, MD

Blood (2019) 134 (Supplement_1): 4552.

https://doi.org/10.1182/blood-2019-122966

Published: 2019

Journal Articles

Intrabone Delivery of CD34+ Cells Using an Optimized Delivery System Does Not Enhance Engraftment in a Rhesus Macaque Model of Hematopoietic Stem Cell Transplantation

Blood (2018) 132 (Supplement 1): 5677.

https://doi.org/10.1182/blood-2018-99-114730

Published: 2018

Journal Articles

Rapid Engraftment and Immune Recovery in Treatment Refractory Severe Aplastic Anemia Patients Undergoing Ex Vivo Nicotinamide-Expanded (NAM-Expanded) Unrelated Cord Blood Transplantation

Richard W. Childs, MD, Phuong T. Vo, MD, Georg Aue, Jennifer Wilder, Brian Wells, Joseph Clara, MD, Reem Shalabi, Patricia Prince, David F. Stroncek, Robert Reger, MS, Willy A. Flegel, MD, Sharon Adams, MT, CHS (ABHI), Kristen Gunn, Tatyana Worthy, Lisa Cook, Xin Tian

Blood (2018) 132 (Supplement 1): 5789.

https://doi.org/10.1182/blood-2018-99-119546

Published: 2018

Journal Articles

Durable Remission of Refractory and Advanced Stage Mycosis Fungoides/Sezary Syndrome (MF/SS) Utilizing an "Outpatient" Alemtuzumab and Fludarabine-Based Reduced Intensity Allogeneic Peripheral Blood Stem Cell Transplantation (PBSCT)

Phuong Vo, Ramaprasad Srinivasan, Enkhtsetseg Purev, MD PhD, Emily McDuffee, Lisa Cook, Tatyana Worthy, Geri Hawks, Prince Patricia, Reem Shalabi, Brian Wells, Robert Reger, MS, Hanh Khuu, David Stroncek, Xin Tian, PhD, Nancy Geller, Georg Aue, Richard Childs, MD

Blood (2017) 130 (Supplement 1): 1962.

https://doi.org/10.1182/blood.V130.Suppl_1.1962.1962

Published: 2017

Journal Articles

Final Result of a Pilot Study Using Eculizumab to Overcome Platelet Transfusion Refractoriness in Allo-Immunized Patients Receiving HLA Mismatched Platelets

Phuong Vo, Enkhtsetseg Purev, MD PhD, Kamille West, Emily McDuffee, Tatyana Worthy, Lisa Cook, Geri Hawks, Brian Wells, Reem Shalabi, Patricia Prince, Tom Hughes, Willy Fleigel, Sharon Adams, MT, CHS (ABHI), Robert Reger, MS, Xin Tian, PhD, Georg Aue, Richard Childs, MD

Blood (2017) 130 (Supplement 1): 1119.

https://doi.org/10.1182/blood.V130.Suppl_1.1119.1119

Published: 2017

Journal Articles

High-Efficiency Lentiviral Genetic Modification of Primary Human Natural Killer Cells

Giacomo Waller, BS, David Allan, Dhana Chinnasamy, MSc, PhD, Mala Chakraborty, PhD, Emily Levy, MS, Michael Hochman, MD, Long Chen, MD PhD, Akkapon Poolcharoen, Georg Aue, Kate Stringaris, MD PhD, Robert Reger, MS, Richard Childs, MD

Blood (2017) 130 (Supplement 1): 5566.

https://doi.org/10.1182/blood.V130.Suppl_1.5566.5566

Published: 2017

Journal Articles

Clinical-Grade mRNA Electroporation of NK Cells: A Novel and Highly Efficient Method to Genetically Reprogram Human NK Cells for Cancer Immunotherapy

Mattias Carlsten, MD PhD, Linhong Li, Su Su, MD PhD, Maria Berg, Robert Reger, Madhusudan V. Peshwa, Richard Childs, MD

Blood (2014) 124 (21): 2153.

https://doi.org/10.1182/blood.V124.21.2153.2153

Published: 2014

Journal Articles

Rhesus Macaque NK Cells Expanded Ex Vivo Undergo Similar Phenotypic and Functional Changes Observed With Expanded Human NK Cells Providing An Excellent Model To Optimize Adoptive NK Cell Transfer

Jan K. Davidson-Moncada, MD, PhD, Richard Childs, MD, Cynthia E. Dunbar, MD, Robert Reger, Ritesh Kotecha, Maria Berg, Chuanfeng Wu, PhD

Blood (2013) 122 (21): 2028.

https://doi.org/10.1182/blood.V122.21.2028.2028

Published: 2013

Journal Articles

Inhaled Cyclosporine For The Treatment Of Bronchiolitis Obliterans Following Hematopoietic Stem Cell Transplantation (HSCT) Or Lung Transplantation

Nicole Gormley, MD, Catalina Ramos, RN, BSN, Robert Reger, Margaret Tropea, Xin Tian, PhD, Elena Cho, RN, MSN, Debra Reda, RN, Michael Terrin, MD, Leigh Samsel, MS, Millie Whatley, James Shelhamer, MD, Clara C. Chen, MD, Minoo Battiwalla, MD, MS, A. John Barrett, Tim Corcoran, PhD, Aldo Iacono, MD, J. Philip McCoy, PhD, Anthony Suffredini, MD, Richard W. Childs, MD

Blood (2013) 122 (21): 2057.

https://doi.org/10.1182/blood.V122.21.2057.2057

Published: 2013

Journal Articles

Forced Fucosylation With ASC-101 Enhances The Binding Of Ex Vivo Expanded Human NK Cells To E-Selectin: A Novel Method To Improve The Homing Of Adoptively Transferred NK Cells To The Bone Marrow In Patients With Hematological Malignancies

Toshihiro Onishi, MD, Maria Berg, Robert Reger, Leonard Miller, PhD, Steve Wolpe, Lynnet Koh, MS, MBA, Richard Childs, MD

Blood (2013) 122 (21): 4499.

https://doi.org/10.1182/blood.V122.21.4499.4499

Published: 2013

Journal Articles

High Dose Plerixafor Is Safe and Mobilizes Higher Numbers of CD34+ Cells Compared with Standard Dose Plerixafor

Jeremy M Pantin, MB.BS., Xin Tian, Ph.D., Matthew M. Hsieh, MD, Lisa Cook, RN, BSN, Theresa Donohue, MHS, PA-C, Elena Cho, RN MSN, Aleah Smith, Robert Reger, Thomas Trischman, PhD, Hanh Khuu, MD, Richard Childs, MD

Blood (2012) 120 (21): 585.

https://doi.org/10.1182/blood.V120.21.585.585

Published: 2012

Journal Articles

Nicotinamide (NAM) Increases Surface Expression of CD62L On in Vitro Expanded NK Cells

Ewelina K. Mamcarz, MD, Maria Berg, Tony Peled, Gabi M Frei, Robert Reger, Xin Tian, Ph.D., Richard Childs, MD

Blood (2012) 120 (21): 4355.

https://doi.org/10.1182/blood.V120.21.4355.4355

Published: 2012

Journal Articles

Co-Infusion of Allogeneic Cord Blood with Haploidentical CD34+ Cells Improved Transplant Outcome for Patients with Severe Aplastic Anemia Undergoing Cord Blood Transplantation

Blood (2011) 118 (21): 654.

https://doi.org/10.1182/blood.V118.21.654.654

Published: 2011

Journal Articles

Systemically Administered Hydrocortisone Exerts Differential Effects on B and T Lymphocytes and Natural Killer Cells in Healthy Donors

Matthew J. Olnes, MD, PhD, Angelique Biancotto, PhD, Ena Wang, M.D., Robert Reger, Shira Perl, MD, Howard Dickler, MD, J. Philip McCoy, PhD, Francesco Marincola, M.D., Richard Childs, MD, Neal S. Young, MD

Blood (2011) 118 (21): 2179.

https://doi.org/10.1182/blood.V118.21.2179.2179

Published: 2011

Journal Articles

IL-17A-Expressing CD4+ T Cells Must Acquire the Expression of T-Bet and IFN-γto Destroy Tumor Cells In Vivo.

Pawel Muranski, MD, Sid P Kerkar, Zachary A Borman, Robert Reger, Luis Sanchez-Perez, Christian S Hinrichs, Zhiya Yu, Douglas C Palmer, Luca Gattinoni, Nicholas P. Restifo

Blood (2009) 114 (22): 468.

https://doi.org/10.1182/blood.V114.22.468.468

Published: 2009

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Allogeneic Peripheral Blood Stem Cell Transplantation for Bone Marrow Failure Syndromes Using CD34 + -Selected Progenitor Cells Co-Infused with a Reduced Number of Non-Mobilized T-Cells

CRISPR Gene-Editing of Chemokine Receptors As a Novel Strategy to Redirect NK Cell Trafficking In Vivo

Cell Density of NK Cells during Ex Vivo Expansion Impacts NK Cell Surface TRAIL Expression

Rapid Engraftment, Immune Recovery, and Resolution of Transfusion Dependence in Treatment-Refractory Severe Aplastic Anemia Following Transplantation with Ex Vivo Expanded Umbilical Cord Blood (Omidubicel)

Effect of Cyclosporine Inhalation Solution (CIS) on Lung Function and Inflammatory Biomarkers in Patients with Hematopoietic Stem Cell Transplant (HSCT) Associated Bronchiolitis Obliterans Syndrome (BOS)

Intrabone Delivery of CD34+ Cells Using an Optimized Delivery System Does Not Enhance Engraftment in a Rhesus Macaque Model of Hematopoietic Stem Cell Transplantation

Rapid Engraftment and Immune Recovery in Treatment Refractory Severe Aplastic Anemia Patients Undergoing Ex Vivo Nicotinamide-Expanded (NAM-Expanded) Unrelated Cord Blood Transplantation

Durable Remission of Refractory and Advanced Stage Mycosis Fungoides/Sezary Syndrome (MF/SS) Utilizing an "Outpatient" Alemtuzumab and Fludarabine-Based Reduced Intensity Allogeneic Peripheral Blood Stem Cell Transplantation (PBSCT)

Final Result of a Pilot Study Using Eculizumab to Overcome Platelet Transfusion Refractoriness in Allo-Immunized Patients Receiving HLA Mismatched Platelets

High-Efficiency Lentiviral Genetic Modification of Primary Human Natural Killer Cells

Clinical-Grade mRNA Electroporation of NK Cells: A Novel and Highly Efficient Method to Genetically Reprogram Human NK Cells for Cancer Immunotherapy

Rhesus Macaque NK Cells Expanded Ex Vivo Undergo Similar Phenotypic and Functional Changes Observed With Expanded Human NK Cells Providing An Excellent Model To Optimize Adoptive NK Cell Transfer

Inhaled Cyclosporine For The Treatment Of Bronchiolitis Obliterans Following Hematopoietic Stem Cell Transplantation (HSCT) Or Lung Transplantation

Forced Fucosylation With ASC-101 Enhances The Binding Of Ex Vivo Expanded Human NK Cells To E-Selectin: A Novel Method To Improve The Homing Of Adoptively Transferred NK Cells To The Bone Marrow In Patients With Hematological Malignancies

High Dose Plerixafor Is Safe and Mobilizes Higher Numbers of CD34+ Cells Compared with Standard Dose Plerixafor

Nicotinamide (NAM) Increases Surface Expression of CD62L On in Vitro Expanded NK Cells

Co-Infusion of Allogeneic Cord Blood with Haploidentical CD34+ Cells Improved Transplant Outcome for Patients with Severe Aplastic Anemia Undergoing Cord Blood Transplantation

Systemically Administered Hydrocortisone Exerts Differential Effects on B and T Lymphocytes and Natural Killer Cells in Healthy Donors

IL-17A-Expressing CD4+ T Cells Must Acquire the Expression of T-Bet and IFN-γto Destroy Tumor Cells In Vivo.

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American Society of Hematology

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