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Quentin Kimmerlin
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Journal Articles

AJ1-11095, a potent and highly selective type-II JAK2 inhibitor, shows enhanced therapeutic efficacy as compared with type-I JAK2 inhibitor ruxolitinib in models of myeloproliferative neoplasms (MPNs)

Free
Marc Usart, Shivam Rai, Kavi O'Connor, Quentin Kimmerlin, Zachary Zaroogian, Matthew Wereski, Charlie Xu, Craig Masse, Stevan Hubbard, Ross Levine, Maria Kleppe, Radek Skoda, Andrew Dunbar
Journal: Blood
Blood (2025) 146 (Supplement 1): 1983.
https://doi.org/10.1182/blood-2025-1983
Published: 2025
Journal Articles

JAK2 -V617F-Driven Myeloproliferative Neoplasms (MPN) Are Initiated By a Subset of HSCs Marked By High Expression of the Vwf-GFP Reporter Gene

Free
Quentin Kimmerlin, Marc Usart, Tiago Fonseca, Hui Hao-Shen, Radek C. Skoda
Journal: Blood
Blood (2024) 144 (Supplement 1): 751.
https://doi.org/10.1182/blood-2024-206909
Published: 2024
Journal Articles

Loss of Dnmt3a increases self-renewal and resistance to pegIFN-α in JAK2 -V617F–positive myeloproliferative neoplasms

Free
Marc Usart, Jan Stetka, Damien Luque Paz, Nils Hansen, Quentin Kimmerlin, Tiago Almeida Fonseca, Melissa Lock, Lucia Kubovcakova, Riikka Karjalainen, Hui Hao-Shen, Anastasiya Börsch, Athimed El Taher, Jessica Schulz, Jean-Christophe Leroux, Stefan Dirnhofer, Radek C. Skoda
Journal: Blood
Blood (2024) 143 (24): 2490–2503.
https://doi.org/10.1182/blood.2023020270
Published: 2024
Includes: Supplemental data
Journal Articles

Cellular Barcoding of JAK2 -V617F Hematopoietic Stem Cells Reveals No Substantial Preferences in the Contribution of Individual Stem Cell Clones to Erythroid Versus Megakaryocytic Lineages

Free
Marc Usart, Tiago Almeida, Julien Roux, Athimed El Taher, Riikka Karjalainen, Quentin Kimmerlin, Shivam Rai, Hui Hao-Shen, Radek C. Skoda
Journal: Blood
Blood (2023) 142 (Supplement 1): 859.
https://doi.org/10.1182/blood-2023-181695
Published: 2023
Journal Articles

Role of Tubulin Detyrosination in Platelet Biogenesis

Free
Quentin Kimmerlin, Sylvie Moog, Lea Mallo, Catherine Strassel, Carsten Janke, Francois Lanza
Journal: Blood
Blood (2023) 142 (Supplement 1): 1202.
https://doi.org/10.1182/blood-2023-180811
Published: 2023
Journal Articles

Loss of α4A- and β1-tubulins leads to severe platelet spherocytosis and strongly impairs hemostasis in mice

Free
Quentin Kimmerlin, Sylvie Moog, Alexandra Yakusheva, Catherine Ziessel, Anita Eckly, Monique Freund, Gábor Závodszky, Yannick Knapp, Pierre Mangin, François Lanza
Journal: Blood
Blood (2022) 140 (21): 2290–2299.
https://doi.org/10.1182/blood.2022016729
Published: 2022
Includes: Multimedia, Supplemental data