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Nogayhan Seymen
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Journal Articles

Xeroderma pigmentosum as a germline predisposition syndrome for haematological malignancies

Free
Manar Alfaham, Yousef Binamer, Ghulam Mufti, Adam Alfadil, Abdullah Alsuwaidan, Mansour Alfayez, Ahmed Alotaibi, Fahad Almohareb, Amal Hejab, Ali Alahmari, Ayman Saad, Hanan Alkhaldi, Ahmed Alfares, Midrar Alhossiny, Nasir Bakshi, Abouelhoda Mohamed, Najlaa Filimban, Nogayhan Seymen, Mohammad M Karimi, Haitham Khogeer, Riad Youniss, Mahmoud Aljurf, Hazza Alzahrani, Syed Ahmed
Journal: Blood
Blood (2025) 146 (Supplement 1): 6749.
https://doi.org/10.1182/blood-2025-6749
Published: 2025
Journal Articles

The CSMD1 gene is involved in hematopoietic stem cell HSC pruning in patients with acquired immune-mediated aplastic anemia

Free
Antonio Risitano, Deniz Ece Kaya, Simona Iacobelli, Riley Cook, Giorgio Napolitani, Sila Gerlevik, Mohammad M Karimi, Nogayhan Seymen, Flore Sicre-de-Fontbrune, Morag Griffin, Camilla Frieri, Carlo Dufour, Regis Peffault De Latour, Ghulam Mufti, Austin Kulasekararaj
Journal: Blood
Blood (2025) 146 (Supplement 1): 4982.
https://doi.org/10.1182/blood-2025-4982
Published: 2025
Journal Articles

Deep immune signature of immune-mediated aplastic anemia patients shows distinct subsets of regulatory T cells associated with response to treatment: Results from the phase 3, randomized EBMT race clinical trial

Free
Sila Gerlevik, Giorgio Napolitani, Deniz Ece Kaya, Riley Cook, Simona Iacobelli, Nogayhan Seymen, Mohammad M Karimi, Flore Sicre-de-Fontbrune, Morag Griffin, Camilla Frieri, Constantijn Halkes, Christian Recher, Fiorenza Barraco, Edouard Forcade, Jean-Baptiste Mear, Marica Laurino, Beatrice Drexler, Etienne Daguindau, Marleen Van Os, Sofie Terwel, Carlo Dufour, Regis Peffault De Latour, Antonio Risitano, Austin Kulasekararaj, Ghulam Mufti
Journal: Blood
Blood (2025) 146 (Supplement 1): 26.
https://doi.org/10.1182/blood-2025-26
Published: 2025
Journal Articles

Dynamics of Oligoclonal Hematopoiesis in Severe Aplastic Anemia Patients Undergoing Immunosuppressive Treatment: Longitudinal Somatic Mutation Analysis from the EBMT Race Trial

Free
Denise Kaya, Riley Cook, Simona Iacobelli, Austin G. Kulasekararaj, Giorgio Napolitani, Sila Gerlevik, Nogayhan Seymen, Flore Sicre de Fontbrune, Morag Griffin, Camilla Frieri, Constantijn J.M. Halkes, Christian Recher, Fiorenza Barraco, Edouard Forcade, Jean-Baptiste Méar, Marica Laurino, Beatrice Drexler, Etienne Daguindau, Marleen Van Os, Sofie Terwel, Carlo Dufour, Mohammad M. Karimi, Regis Peffault De Latour, Antonio M Risitano, Ghulam Mufti
Journal: Blood
Blood (2024) 144 (Supplement 1): 33.
https://doi.org/10.1182/blood-2024-206632
Published: 2024
Journal Articles

Clonal Haematopoiesis with TP53 Mutations Exhibits Abnormal Erythropoiesis and Erythroid Metabolic Stress

Free
Xuesen Zheng, Prodromos Chatzikyriakou, Louis-Francois Handfield, Maroof Hasan, Diego A. Pereira-Martins, Sarah J Mackie, Maria del Pilar Casares Alaez, Isabel Weinhäuser, Nogayhan Seymen, Kai Yi Mok, Viktorija Uksaite, Marta Rzepkowska, Laarni Bogaanay, Matthew Sadler, Jovan Mircetic, Martin Bornhäuser, James Carmichael, Daniel Bromage, Pramila Krishnamurthy, Rajasekhar N.V.S. Suragani, Ghulam Mufti, Giorgio Napolitani, Anita K. Gandhi, Lynn Quek
Journal: Blood
Blood (2024) 144 (Supplement 1): 944.
https://doi.org/10.1182/blood-2024-200108
Published: 2024
Journal Articles

Saudi Acute Myeloid Leukaemia (AML) Genome Reveals Significant Differences from That in the Western Population

Free
Manar S Alfaham, Syed Osman Ahmed, Nogayhan Seymen, Mohamed Abouelhoda, Najlaa Filimban, Ahmed Alotaibi, Midrar Alhossiny, Brian Meyer, Abdullah Alsuwaidan, Hazza A. Alzahrani, Mahmoud Aljurf, Walid Rasheed, Marwan Shaheen, Fahad Almohareb, Naeem A. Chaudhri, Fahad Alsharif, Amal Hejab, Ahmed Alnughmush, Balqees Alzayed, Nasir Bakshi, Deniz Ece Kaya, Mehrdad Ovesisi, Dorota Monies, Warisha Mumtaz, Haitham A. Khogeer, Riad Youniss, Mohammad M Karimi, Ghulam J Mufti
Journal: Blood
Blood (2024) 144 (Supplement 1): 4231.
https://doi.org/10.1182/blood-2024-205025
Published: 2024
Journal Articles

An Integrated Single Cell Immunogenomic Atlas Reveals Pathways of Clonal Expansion, Inflammation and Dyserythropoiesis in Low and High-Risk Clonal Haematopoiesis

Free
Xuesen Zheng, Amandine Tan, Maria del Pilar Casares Alaez, Garry Mallett, Deniz Ece Kaya, Nogayhan Seymen, Marta Rzepkowska, Sarah Mackie, Prodromos Chatzikyriakou, Laarni Bogaanay, Jen Lewis, Maroof Hasan, Rajasekhar N.V.S. Suragani, James Carmichael, Ghulam Mufti, Anita K. Gandhi, Giorgio Napolitani, Lynn Quek
Journal: Blood
Blood (2023) 142 (Supplement 1): 812.
https://doi.org/10.1182/blood-2023-174947
Published: 2023
Journal Articles

Multi-Omics Factor Analysis (MOFA) Identifies Transposable Element Expression As a Risk Factor and Inflammaging As a Protective Factor in Myelodysplastic Syndromes

Free
Shan Hama, Nogayhan Seymen, Sila Gerlevik, Deniz Ece Kaya, Giorgio Napolitani, Seishi Ogawa, Ghulam Mufti, Mohammad M. Karimi
Journal: Blood
Blood (2023) 142 (Supplement 1): 6450.
https://doi.org/10.1182/blood-2023-177683
Published: 2023