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Journal Articles

Therapeutic potential of mitochondrial transplantation in the treatment of MDS

Free
Takeshi Fujino, Tina Napso, Gat Pozner, Oren Ziv, Ksenia Magidey Klein, Niv Sabath, Noa Avni, Neta Kutner, Hanan Khoury, Cynthia Castro, Nina Fox, Alexander Lewis, Steven Tittley, Sam Taylor, Natalie Ohana, Noa Sher, Yishai Ofran, Omar Abdel-Wahab
Journal: Blood
Blood (2025) 146 (Supplement 1): 231.
https://doi.org/10.1182/blood-2025-231
Published: 2025
Journal Articles

Development of synthetic introns for selective elimination of U2AF1 mutant MDS

Free
Qian Zhang, Kuan-Ting Lin, Christian Figueroa-Espada, Yuxi Ai, Salima Benbarche, Jeetayu Biswas, Robert Stanley, Cynthia Castro, Nina Fox, Sumit Rai, Matthew Walter, Timothy Graubert, Qing Feng, Rachel Darman, Daniel Heller, Robert Bradley, Omar Abdel-Wahab
Journal: Blood
Blood (2025) 146 (Supplement 1): 229.
https://doi.org/10.1182/blood-2025-229
Published: 2025
Journal Articles

DYRK1A controls CD47 endocytic degradation and leukemia immune surveillance

Free
Won Jun Kim, Alexander Arnuk, Jeetayu Biswas, Cuijuan Han, Nina Fox, Jacob Winick, Alexander Lewis, Kayla Koenig, Cynthia Castro, Abimbola Lawal, Robert Stanley, Joshua Weinreb, Zachary Zaroogian, Hui Liu, Zhuoning Li, Ileana Miranda, Anurag Sharma, Hilda Amalia Pasolli, Brian Eastman, Gopi Kumar Mittapalli, Chi-Ching Mak, Matthew Jarvis, Mara Monetti, Juan Osorio, Carine Bossard, Omar Abdel-Wahab, Eric Wang
Journal: Blood
Blood (2025) 146 (Supplement 1): 751.
https://doi.org/10.1182/blood-2025-751
Published: 2025
Journal Articles

Development of CD371 shielded hematopoietic stem cell grafts for protection against AML-directed immunotherapies

Free
Satoshi Kaito, Karen Li, Xiaoli Mi, Cynthia Castro, Nina Fox, Alexander Lewis, Adriana Cuibus, Kenyon Weis, Erin Burns, Sarah Yoo, Jahan Rahman, Susan DeWolf, Anthony Daniyan, Omar Abdel-Wahab
Journal: Blood
Blood (2025) 146 (Supplement 1): 2309.
https://doi.org/10.1182/blood-2025-2309
Published: 2025
Journal Articles

CDK4/6 inhibition mitigates chemotherapy-induced expansion of TP53-mutant clonal hematopoiesis

Free
Irenaeus Chan, Pu Zhang, Xiangyu Pan, Cynthia Castro, Nina Fox, Alexander Lewis, Kenyon Weis, Adriana Cuibus, Steven Tittley, Giulia Petrone, John Beeler, Duc Tran, Griffen Mustion, Catrina Fronick, Konrad Stopsack, Carlos Cruchaga, Omar Abdel-Wahab, Kelly Bolton
Journal: Blood
Blood (2025) 146 (Supplement 1): 4.
https://doi.org/10.1182/blood-2025-4
Published: 2025
Journal Articles

Mitochondrial Augmentation of Hematopoietic Stem and Progenitor Cells As a New Therapeutic Approach for Myelodysplasia

Free
Takeshi Fujino, Noa Avni, Neta Kutner, Hanan Khoury, Gat Pozner, Niv Sabath, Cynthia Castro, Nina Fox, Alexander M. Lewis, Steven Tittley, Oren Ziv, Yishai Ofran, Tina Napso, Natalie Yivgi Ohana, Noa Sher, Omar Abdel-Wahab
Journal: Blood
Blood (2024) 144 (Supplement 1): 4772.
https://doi.org/10.1182/blood-2024-200129
Published: 2024
Journal Articles

Mis-Splicing Derived Neoantigens and Cognate T Cell Receptors in Splicing Factor Mutant Myeloid Neoplasms

Free
Won Jun Kim, Edie I. Crosse, Emma De Neef, Inaki Etxeberria, Erich Sabio, Eric Wang, Jan Philipp Bewersdorf, Sydney X. Lu, Andrea Belleville, Nina Fox, Cynthia Castro, Pu Zhang, Takeshi Fujino, Jennifer Lewis, Jahan Rahman, Beatrice Zhang, Jacob H. Winick, Alexander M. Lewis, Robert Stanley, Susan Dewolf, Brigita Meskauskaite Urben, Meril Takizawa, Tobias Krause, Henrik Molina, Ronan Chaligne, Priya Koppikar, Jeffrey J. Molldrem, Mathieu Gigoux, Taha Merghoub, Anthony F. Daniyan, Benjamin D. Greenbaum, Christopher A. Klebanoff, Robert K. Bradley, Omar Abdel-Wahab
Journal: Blood
Blood (2024) 144 (Supplement 1): 343.
https://doi.org/10.1182/blood-2024-198639
Published: 2024
Journal Articles

Development of CAR T Cells Targeting U5 snRNP200 for the Treatment of Acute Myeloid and B-Lymphoid Leukemias

Free
Takeshi Fujino, Jennifer Lewis, Bing-Yi Chen, Quinlan Sievers, Winson Cai, Sarah Yoo, Serena Mathew, Sydney Souness, Erin R. Burns, Jasmine S. Um, Elisa De Stanchina, Qing Chang, Besnik Qeriqi, Kevin Chen, PU Zhang, Susan Dewolf, Alexander M. Lewis, Kenyon Weis, Brianna Gipson, Cynthia Castro, Nina Fox, Satoshi Kaito, Alyssa Fronk, Martin Akerman, Omar Abdel-Wahab, Anthony F. Daniyan
Journal: Blood
Blood (2024) 144 (Supplement 1): 371.
https://doi.org/10.1182/blood-2024-204143
Published: 2024
Journal Articles

Genome-Wide Mapping of R-Loops in Single Cells Reveals Cell-Type Specific Roles for R-Loops in Hematopoietic Cell Identity

Free
Bin Lu, Pu Zhang, Sisi Chen, Salima Benbarche, Cynthia Castro, Nina Fox, Mohammad Abubakar, Jeetayu Biswas, Ruslan Soldatov, Richard Koche, Omar Abdel-Wahab
Journal: Blood
Blood (2023) 142 (Supplement 1): 242.
https://doi.org/10.1182/blood-2023-180913
Published: 2023
Journal Articles

Systematic Evaluation of AML-Associated Antigens Identifies Novel Anti-U5 snRNP200 Therapeutic Antibodies for the Treatment of AML

Free
Katherine Knorr, Caroline Erickson, Eric Wang, Jahan Rahman, Xiaoli Mi, Sydney Lu, Nina Fox, Alex Penson, Simon Hogg, Robert Stanley, Daichi Inoue, David Knorr, Jeffrey Ravetch, Omar Abdel-Wahab
Journal: Blood
Blood (2022) 140 (Supplement 1): 2247–2248.
https://doi.org/10.1182/blood-2022-158445
Published: 2022