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Nadezda Dolgikh
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Journal Articles

Menin-inhibition boosts CAR-T cell therapy against NPM1 mutated and KMT2A-rearranged acute myeloid leukemia

Free
Johanna Rausch, Philipp Wendel, Viktor Fetsch, Marie Kuhmann, Lilian Viehböck, Fenja Gierschek, Najla Abassi, Margarita Dzama, Nadezda Dolgikh, Lea Knapp, Jan Habermann, Catharina Lahrmann, Ann-Katrin Gebel, Matthias Klein, Michael Delacher, Catherine Wölfel, Hakim Echchannaoui, Matthias Theobald, Daniel Sasca, Federico Marini, Robert Zeiser, Evelyn Ullrich, Michael Kühn
Journal: Blood
Blood (2025) 146 (Supplement 1): 866.
https://doi.org/10.1182/blood-2025-866
Published: 2025
Journal Articles

Synergistic Efficacy of Dual Menin and PRMT5 Targeting Against NPM1 mutated and KMT2A- rearranged Leukemia

Free
Nadezda Dolgikh, Johanna Rausch, Marlene Steiner, Jonas Schönfeld, Catharina Lahrmann, Nina Hilke, Maria Alejandra Vila Molerio, Simon Weisemann, Maria Saura-Pañella, Aarón Gallego-Crespo, Matthias Theobald, Daniel Sasca, Chun-Wei David Chen, Michael W.M. Kühn
Journal: Blood
Blood (2024) 144 (Supplement 1): 206.
https://doi.org/10.1182/blood-2024-202460
Published: 2024
Journal Articles

The Menin Inhibitor Ziftomenib (KO-539) Synergizes with Agents Targeting Chromatin Regulation or Apoptosis and Sensitizes AML with MLL Rearrangement or NPM1 Mutation to Venetoclax

Free
Johanna Rausch, Margarita M. Dzama, Nadezda Dolgikh, Hanna Stiller, Stephan Bohl, Catharina Lahrmann, Kerstin Kunz, Linda Kessler, Hakim Echchannaoui, Chun-Wei David Chen, Thomas Kindler, Francis Burrows, Matthias Theobald, Daniel Sasca, Scott A. Armstrong, Michael Kuehn
Journal: Blood
Blood (2022) 140 (Supplement 1): 6226–6227.
https://doi.org/10.1182/blood-2022-167566
Published: 2022