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Journal Articles

Comparing Outcomes between CPX-351 and Fludarabine-Based Induction in Secondary Acute Myeloid Leukemia in the Real-World Setting: The Prognostic Role of Measurable Residual Disease

Free
Carola Riva, Paola Minetto, Maria Chies, Elena Maio, Ylenia Azzanelli, Giada Zecchetti, Nicoletta Colombo, Sara Rosellini, Alessia Parodi, Elisabetta Tedone, Enrico Carminati, Giuseppina Fugazza, Paolo Nozza, Michele Cea, Roberto Massimo Lemoli, Fabio Guolo
Journal: Blood
Blood (2024) 144 (Supplement 1): 1482.
https://doi.org/10.1182/blood-2024-198174
Published: 2024
Journal Articles

High Risk Mutations in Critical Genes Do Not Significantly Affect Remission Rates and Minimal Residual Disease Clearance in Acute Myeloid Leukemia Patients Receiving CPX-351 Induction

Free
Fabio Guolo, Carola Riva, Maria Chies, Chiara Vernarecci, Ylenia Azzanelli, Nicoletta Colombo, Sara Rosellini, Alessia Parodi, Elisabetta Tedone, Enrico Carminati, Francesco Puglisi, Clara Nurra, Giuseppina Fugazza, Michele Cea, Roberto Massimo Lemoli, Paola Minetto
Journal: Blood
Blood (2024) 144 (Supplement 1): 1478.
https://doi.org/10.1182/blood-2024-198187
Published: 2024
Journal Articles

Excellent Outcome in NPM1- mutated Acute Myeloid Leukemia Patients Receiving Intensified Fludarabine-Based Induction Is Not Affected By Secondary Type Mutations and Other High Risk Aberrations

Free
Paola Minetto, Carola Riva, Enrico Carminati, Ylenia Azzanelli, Francesco Puglisi, Clara Nurra, Giuseppina Fugazza, Antonia Cagnetta, Michele Cea, Roberto Massimo Lemoli, Fabio Guolo
Journal: Blood
Blood (2024) 144 (Supplement 1): 4239.
https://doi.org/10.1182/blood-2024-198171
Published: 2024
Journal Articles

Real World Evidence of Efficacy of CPX-351 in Secondary Acute Myeloid Leukemia Defined According to Who 2022 Classification

Free
Carola Riva, Paola Minetto, Maria Chies, Chiara Vernarecci, Giada Zecchetti, Elena Maio, Ylenia Azzanelli, Nicoletta Colombo, Sara Rosellini, Alessia Parodi, Elisabetta Tedone, Enrico Carminati, Francesco Puglisi, Clara Nurra, Giuseppina Fugazza, Paolo Nozza, Michele Cea, Roberto Massimo Lemoli, Fabio Guolo
Journal: Blood
Blood (2024) 144 (Supplement 1): 1471.
https://doi.org/10.1182/blood-2024-197943
Published: 2024
Journal Articles

High Efficacy and Feasibility of a Full Pediatric Induction in Adults Aged up to 55 Years with Philadelphia-Negative Acute Lymphoblastic Leukemia

Free
Chiara Vernarecci, Elena Maio, Mattia Montanari, Francesco Puglisi, Clara Nurra, Maurizio Miglino, Nicoletta Colombo, Enrico Carminati, Giada Zecchetti, Maria Chies, Beatrice Ferro, Massimo Zucchetti, Antonia Cagnetta, Michele Cea, Elisabetta Tedone, Roberto Massimo Lemoli, Fabio Guolo, Paola Minetto
Journal: Blood
Blood (2023) 142 (Supplement 1): 5879.
https://doi.org/10.1182/blood-2023-185082
Published: 2023
Journal Articles

Deciphering the Immune Microenvironment in Waldenstrom's Macroglobulinemia

Free
Antonio Sacco, Vanessa Desantis, Jon Celay, Viviana Giustini, Fabio Rigali, Francesco Savino, Michele Cea, Debora Soncini, Antonia Cagnetta, Antonio Giovanni Solimando, Deborah D'Aliberti, Silvia Spinelli, Daniele Ramazzotti, Camillo Almici, Katia Todoerti, Antonino Neri, Antonella Anastasia, Alessandra Tucci, Marina Motta, Marco Chiarini, Yawara Kawano, Jose A Martinez-Climent, Rocco Piazza, Aldo Roccaro
Journal: Blood
Blood (2023) 142 (Supplement 1): 4690.
https://doi.org/10.1182/blood-2023-188408
Published: 2023
Journal Articles

Higher CD56 Expression on Multiple Myeloma Cells Increases CD38 Expression, Reduces Intracellular NAD+ Levels, and Enhances the Efficacy of Daratumumab-Based Treatment Strategies

Free
Giulia Giorgetti, Pamela Becherini, Elena Maroto-Martin, Daniela Fenoglio, Debora Soncini, Claudia Martinuzzi, Santina Bruzzone, Andrea Benzi, Aimable Nahimana, Chiara Rosa Maria Uras, Anaïs Schavgoulidze, Jessica Ng Fong, Roberto M. Lemoli, Nikhil C Munshi, Mariateresa Fulciniti, Michele Cea
Journal: Blood
Blood (2023) 142 (Supplement 1): 1951.
https://doi.org/10.1182/blood-2023-189439
Published: 2023
Journal Articles

Single Agent Tagraxofusp in Relapsed/Refractory CD123-Positive Acute Myeloid Leukemia: A Preliminary Analysis of Italian Gimema AML2020 Trial

Free
Paola Minetto, Sara Rosellini, Fabio Guolo, Elisabetta Tedone, Ernesta Audisio, Chiara Cattaneo, Monica Bocchia, Nicola Fracchiolla, Maria Paola Martelli, Enrico Crea, Enrico Carminati, Livia Gorreo Renzulli, Giuseppina Fugazza, Alfonso Piciocchi, Giovanni Ottonelli, Maurizio Miglino, Michele Cea, Antonio Curti, Livio Pagano, Adriano Venditti, Tariq Mughal, Roberto Massimo Lemoli
Journal: Blood
Blood (2023) 142 (Supplement 1): 2918.
https://doi.org/10.1182/blood-2023-189417
Published: 2023
Journal Articles

Post-Transplant Nivolumab Plus Unselected Autologous Lymphocytes in Truly Refractory Hodgkin Lymphoma Patients Is Highly Effective and Responses Are Mediated By NK Cells

Free
Fabio Guolo, Paola Minetto, Silvia Pesce, Filippo Ballerini, Marco Greppi, Matteo Bozzo, Michele Cea, Maurizio Miglino, Andrea Todiere, Elisabetta Tedone, Nicoletta Colombo, Alessandra Bò, Alberto Serio, Silvia Luchetti, Alida Dominietto, Riccardo Varaldo, Simona Candiani, Marco Mora, Paolo Nozza, Genny Del Zotto, Emanuela Marcenaro, Roberto M. Lemoli
Journal: Blood
Blood (2023) 142 (Supplement 1): 2218.
https://doi.org/10.1182/blood-2023-189574
Published: 2023
Journal Articles

Mutational Burden in High Risk Genes Do Not Affect Remission Rates and MRD Clearance in Elderly AML Patients Receiving CPX-351 Induction

Free
Carola Riva, Paola Minetto, Enrico Carminati, Maria Chies, Chiara Vernarecci, Beatrice Ferro, Elena Maio, Giada Zecchetti, Michela Frello, Maurizio Miglino, Elisabetta Tedone, Nicoletta Colombo, Clara Nurra, Francesco Puglisi, Antonia Cagnetta, Michele Cea, Giuseppina Fugazza, Roberto Massimo Lemoli, Fabio Guolo
Journal: Blood
Blood (2023) 142 (Supplement 1): 6016.
https://doi.org/10.1182/blood-2023-186555
Published: 2023
Journal Articles

The NAD + Metabolic Dependency Restriction Overcomes Drug-Resistance Phenotype of Multiple Myeloma CELLS

Free
Debora Soncini, Pamela Becherini, Silvia Ravera, Claudia Martinuzzi, Alessio Nencioni, Santina Bruzzone, Francesco Piacente, Giulia Giorgetti, Francesco Ladisa, Michel A. Duchosal, Aimable Nahimana, Roberto M. Lemoli, Michele Cea
Journal: Blood
Blood (2023) 142 (Supplement 1): 6609.
https://doi.org/10.1182/blood-2023-189720
Published: 2023
Journal Articles

Targeting the immune microenvironment in Waldenström macroglobulinemia via halting the CD40/CD40-ligand axis

Free
Antonio Sacco, Vanessa Desantis, Jon Celay, Viviana Giustini, Fabio Rigali, Francesco D. Savino, Michele Cea, Debora Soncini, Antonia Cagnetta, Antonio G. Solimando, Deborah D’Aliberti, Silvia Spinelli, Daniele Ramazzotti, Camillo Almici, Katia Todoerti, Antonino Neri, Antonella Anastasia, Alessandra Tucci, Marina Motta, Marco Chiarini, Yawara Kawano, Jose A. Martinez-Climent, Rocco Piazza, Aldo M. Roccaro
Journal: Blood
Blood (2023) 141 (21): 2615–2628.
https://doi.org/10.1182/blood.2022019240
Published: 2023
Includes: Supplemental data
Journal Articles

The Multi-Kinases Inhibitor ARQ531 Enhanches Anti-MM Activity of Imids By Dual Deregulation of MAP- and Cyclin-Dependent Kinases Activities

Free
Debora Soncini, Pamela Becherini, Elisa Gelli, Claudia Martinuzzi, Fabio Guolo, Antonino Neri, Antonia Cagnetta, Roberto Massimo Lemoli, Michele Cea
Journal: Blood
Blood (2022) 140 (Supplement 1): 9929.
https://doi.org/10.1182/blood-2022-169453
Published: 2022
Journal Articles

Clonal Hematopoiesis: Exploiting Molecular Landscape of Multiple Myeloma Patients for Choosing the Most Appropriate Therapeutic Strategy

Free
Elisa Gelli, Antonella Laudisi, Claudia Martinuzzi, Debora Soncini, Pamela Becherini, Fabio Guolo, Concetta Conticello, Daniele Derudas, Francesco Di Raimondo, Antonia Cagnetta, Domenico Coviello, Roberto Massimo Lemoli, Michele Cea
Journal: Blood
Blood (2022) 140 (Supplement 1): 7064–7065.
https://doi.org/10.1182/blood-2022-169263
Published: 2022
Journal Articles

Post-Transplant Nivolumab Plus Unselected Autologous Lymphocytes in Refractory Hodgkin Lymphoma: A Feasible and Promising Salvage Therapy Associated with Expansion and Maturation of NK Cells

Free
Fabio Guolo, Paola Minetto, Silvia Pesce, Filippo Ballerini, Michele Cea, Michela Frello, Matteo Garibotto, Chiara Vernarecci, Marco Greppi, Matteo Bozzo, Chiara Salvetti, Andrea Todiere, Elisabetta Tedone, Nicoletta Colombo, Alessia Parodi, Alessandra Bo, Paolo Carlier, Alberto Serio, Silvia Luchetti, Alida Dominietto, Riccardo Varaldo, Marco Mora, Vanessa Agostini, Paolo Nozza, Emanuela Marcenaro, Genny del Zotto, Roberto Massimo Lemoli
Journal: Blood
Blood (2022) 140 (Supplement 1): 11549–11551.
https://doi.org/10.1182/blood-2022-169136
Published: 2022
Journal Articles

Prognostic Relevance of Minimal Residual Disease in Therapy Related and Secondary Acute Myeloid Leukemia Receiving CPX-351 or Fludarabine-Based Induction

Free
Fabio Guolo, Paola Minetto, Carola Riva, Chiara Vernarecci, Monica Passannante, Francesca Parodi, Michela Frello, Elena Maio, Beatrice Ferro, Maria Chies, Maurizio Miglino, Elisabetta Tedone, Nicoletta Colombo, Enrico Carminati, Clara Nurra, Francesco Puglisi, Antonia Cagnetta, Michele Cea, Roberto Massimo Lemoli
Journal: Blood
Blood (2022) 140 (Supplement 1): 8930–8931.
https://doi.org/10.1182/blood-2022-169394
Published: 2022
Journal Articles

Prognostic Impact of Minimal Residual Disease Assessment in Elderly Patients with Secondary Acute Myeloid Leukemia. a Comparison between CPX-351 and Intensified Fludarabine-Based Regimens

Free
Fabio Guolo, Paola Minetto, Marino Clavio, Maurizio Miglino, Riccardo Marcolin, Monica Passannante, Carola Riva, Michela Frello, Chiara Vernarecci, Elisabetta Tedone, Nicoletta Colombo, Enrico Carminati, Girolamo Pugliese, Clara Nurra, Antonia Cagnetta, Michele Cea, Marco Gobbi, Roberto M. Lemoli
Journal: Blood
Blood (2021) 138 (Supplement 1): 3442.
https://doi.org/10.1182/blood-2021-153060
Published: 2021
Journal Articles

CPX-351 Induction in Secondary Acute Myeloblastic Leukemia: Extended Follow up from the Italian Compassionate Use Program

Free
Paola Minetto, Fabio Guolo, Luana Fianchi, Marino Clavio, Michele Gottardi, Mauro Endri, Sara Galimberti, Giuliana Rizzuto, Margherita Sciumé, Michela Rondoni, Giambattista Bertani, Michelina Dargenio, Atto Billio, Barbara Scappini, Patrizia Zappasodi, Anna Maria Scattolin, Francesco Grimaldi, Giuseppe Pietrantuono, Pellegrino Musto, Cerrano Marco, Stefano D'Ardia, Ernesta Audisio, Alessandro Cignetti, Crescenza Pasciolla, Francesca Pavesi, Anna Candoni, Carmela Gurrieri, Monica Morselli, Caterina Alati, Nicola S Fracchiolla, Giovanni Rossi, Manuela Caizzi, Fabrizio Carnevale Schianca, Michele Cea, Agostino Tafuri, Giuseppe Rossi, Felicetto Ferrara, Livio Pagano, Roberto Massimo Lemoli
Journal: Blood
Blood (2021) 138 (Supplement 1): 1262.
https://doi.org/10.1182/blood-2021-153028
Published: 2021
Journal Articles

Impact of Minimal Residual Disease (MRD) By Multiparameter Flow Cytometry (MFC) and Next-Generation Sequencing (NGS) on Outcome: Results of Newly Diagnosed Transplant-Eligible Multiple Myeloma (MM) Patients Enrolled in the Forte Trial

Free
Stefania Oliva, Elisa Genuardi, Maria Teresa Petrucci, Mattia D'Agostino, MD, Daniel Auclair, Antonio Spadano, Allison P. Jacob, Michele Cea, Luca De Rosa, Alessandro Gozzetti, Marina Ruggeri, Andrea Capra, Milena Gilestro, Norbert Pescosta, Angelo D. Palmas, Agostina Siniscalchi, Ilan R. Kirsch, Paolo Corradini, Pellegrino Musto, Mario Boccadoro, Elena Zamagni, Francesca Gay, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 44–45.
https://doi.org/10.1182/blood-2020-137351
Published: 2020
Journal Articles

Intensive Fludarabine, High Dose Cytarabine and Idarubicin-Based Induction for Younger NPM1-Mutated AML Patient: Overcoming the Negative Prognosis of FLT3-ITD Mutation

Free
Paola Minetto, MD PhD, Anna Candoni, Fabio Guolo, MD, Marino Clavio, MD, Maria Elena Zannier, MD, Maurizio Miglino, PhD, Maria Vittoria Dubbini, MD, Anna Sicuranza, PhD, Sara Ciofini, Elisabetta Tedone, Nicoletta Colombo, PhD, Girolamo Pugliese, Filippo Ballerini, MD, Michele Cea, Monica Bocchia, Renato Fanin, MD, Roberto Massimo Lemoli, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 32–33.
https://doi.org/10.1182/blood-2020-142887
Published: 2020