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Matt Coffey
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Journal Articles

Proteasome Inhibitors Impair the Innate Antiviral Immune Response and Potentiate Pelareorep-Based Viral Therapy in Multiple Myeloma

Free
Ada Dona', PhD, Domenico Viola, Enrico Caserta, PhD, Francesca Besi, PhD, James F Sanchez, PhD, Guido Marcucci, MD, Jonathan J Keats, PhD, Amrita Y. Krishnan, MD, Matt Coffey, PhD, Douglas W. Sborov, MDMSc, Gerard Nuovo, MD, Craig C Hofmeister, MDMPH, Flavia Pichiorri, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1816.
https://doi.org/10.1182/blood-2019-128740
Published: 2019
Journal Articles

Oncolytic Reovirus Immune Priming: A Phase 1b Study of Reolysin with Bortezomib and Dexamethasone in Patients with Relapsed/Refractory Multiple Myeloma

Free
Kevin R. Kelly, MD PhD, Kaijin Wu, PhD, Denice Tsao-Wei, Susan Groshen, Timothy Junius Triche, Jr., PhD, Ann Mohrbacher, Grace Chang, MD, Donna Fernando, Imran N Siddiqi, MD PhD, Matt Coffey, George Gill, Amy Lee, Jennifer S. Carew, PhD, Steffan T. Nawrocki, PhD
Journal: Blood
Blood (2016) 128 (22): 4507.
https://doi.org/10.1182/blood.V128.22.4507.4507
Published: 2016
Journal Articles

A Novel Oncolytic Reovirus Immune Priming Strategy Dramatically Enhances the Efficacy of Anti-PD-L1 Antibody Therapy Against Multiple Myeloma

Free
Kevin R. Kelly, MD PhD, Claudia M. Espitia, Weiguo Zhao, Valeria Visconte, PhD, Matt Coffey, Jennifer S. Carew, PhD, Steffan T. Nawrocki, PhD
Journal: Blood
Blood (2016) 128 (22): 3960.
https://doi.org/10.1182/blood.V128.22.3960.3960
Published: 2016
Journal Articles

Natural Killer Cells Activated By Oncolytic Reovirus Enhance Cetuximab Mediated Antibody Dependent Cellular Cytotoxicity in an in Vitro and In Vivo Model of Colorectal Cancer

Free
Xing Zhao, PhD, Narendiran Rajasekaran, PhD, Cariad Chester, BA, Atsushi Yonezawa, PhD, Suparna Dutt, PhD, Matt Coffey, Zhixu He, MDPhD, Holbrook E Kohrt, MD PhD
Journal: Blood
Blood (2015) 126 (23): 3439.
https://doi.org/10.1182/blood.V126.23.3439.3439
Published: 2015
Journal Articles

Combination Therapy with Reovirus and Immunomodulatory Drugs Induces Direct Oncolytic and Immune-Mediated Killing of Multiple Myeloma Cells and Overcomes Stromal-Mediated Microenvironmental Protection

Free
Christopher Parrish, MD, Gina B Scott, PhD, Matt Coffey, Alan Melcher, MD, Fiona Errington-Mais, PhD, Gordon Cook, MD
Journal: Blood
Blood (2014) 124 (21): 4778.
https://doi.org/10.1182/blood.V124.21.4778.4778
Published: 2014