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Luca Monaco
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Journal Articles

Long-term safety and efficacy of iptacopan in patients with paroxysmal nocturnal hemoglobinuria: 4- and 5-year follow-up of patients from Phase 2 studies who entered the roll-over extension program

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Antonio Risitano, Camilla Frieri, Bor-Sheng Ko, Lily Wong Lee Lee, Alexander Röth, Flore Sicre-de-Fontbrune, Eng Soo Yap, Sung-Soo Yoon, Philippe Ferber, Irina Baltcheva, Aurelie Verles, Silvia Sanz, Luca Monaco, Tim Costigan, Regis Peffault De Latour
Journal: Blood
Blood (2025) 146 (Supplement 1): 3198.
https://doi.org/10.1182/blood-2025-3198
Published: 2025
Journal Articles

Iptacopan monotherapy demonstrated improved clinical outcomes in a real-world cohort with paroxysmal nocturnal hemoglobinuria: Evidence from a managed access program

Free
Silvia Sanz, Abdulfaheem Khan, Sviatlana Rizk, Erik Houtsma, Tim Costigan, Luca Monaco
Journal: Blood
Blood (2025) 146 (Supplement 1): 3202.
https://doi.org/10.1182/blood-2025-3202
Published: 2025
Journal Articles

Oral iptacopan monotherapy demonstrates clinically meaningful hemoglobin increases in patients with paroxysmal nocturnal hemoglobinuria with baseline hemoglobin levels 10 to <12 g/dl on anti-C5 therapy: Subgroup analysis of the appulse-pnh Phase 3b trial

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Austin Kulasekararaj, Flore Sicre-de-Fontbrune, Anna Gaya, Ilene Weitz, David Kuter, David Araten, Bhumika Patel, Abhay Singh, Richard Kelly, Eros Di Bona, Michael Loschi, Vinod Pullarkat, Jörg Schubert, Alessandro Maria Vannucchi, Mustafa Yenerel, Regis Peffault De Latour, Navin Mahajan, Luca Monaco, Tao Ding, Tomasz Lawniczek, Philippe Ferber, Marion Dahlke, Antonio Risitano
Journal: Blood
Blood (2025) 146 (Supplement 1): 4981.
https://doi.org/10.1182/blood-2025-4981
Published: 2025
Journal Articles

The 2-year efficacy and safety of iptacopan monotherapy in patients with paroxysmal nocturnal hemoglobinuria with a history of aplastic anemia on concomitant immunosuppressive therapy who entered the roll-over extension program

Free
Regis Peffault De Latour, Carlos de Castro, Anna Gaya, Morag Griffin, Bing Han, Austin Kulasekararaj, Jaroslaw Maciejewski, Bhumika Patel, Alexander Röth, Phillip Scheinberg, Hubert Schrezenmeier, Yasutaka Ueda, Tim Costigan, Marion Dahlke, Philippe Ferber, Rajeshri Karki, Luca Monaco, Silvia Sanz, Antonio Risitano
Journal: Blood
Blood (2025) 146 (Supplement 1): 4978.
https://doi.org/10.1182/blood-2025-4978
Published: 2025