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Liying Chen
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Journal Articles

Role of Aneuploidy in Transcriptional Regulation and Clinical Prognosis in Relapsed and/or Refractory Multiple Myeloma (RRMM)

Free
Christopher T Su, MD, Liying Chen, MS, Jason Chen, MD, Brian Parkin, MD, Avery Polk, Malathi Kandarpa, PhD, Craig E. Cole, MD, Erica Campagnaro, MD, Josh Vo, PhD, Dan Robinson, PhD, Yi-Mi Wu, PhD, Moshe Talpaz, MD, Jennifer Yesil, MSc, Daniel Auclair, P. Leif Bergsagel, MD, Arul Chinnaiyan, MDPhD, Veerabhadran Baladandayuthapani, PhD, J Christine Ye, MDMSc
Journal: Blood
Blood (2020) 136 (Supplement 1): 45–46.
https://doi.org/10.1182/blood-2020-134558
Published: 2020
Journal Articles

Aneuploidy Is Associated with Inferior Survival in Relapsed Refractory Multiple Myeloma Patients

Free
J Christine Ye, MDMSc, Liying Chen, Jason Chen, MD, Brian Parkin, Avery Polk, Malathi Kandarpa, PhD, Craig E. Cole, MD, Erica L. Campagnaro, MD, Dan Robinson, PhD, Yi-Mi Wu, Moshe Talpaz, MD, Jennifer Yesil, Daniel Auclair, P. Leif Bergsagel, MD, Arul Chinnaiyan, MD, Veerabhadran Baladandayuthapani
Journal: Blood
Blood (2019) 134 (Supplement_1): 4360.
https://doi.org/10.1182/blood-2019-124135
Published: 2019
Journal Articles

Targeting MTHFD2 in Acute Myeloid Leukemia

Free
Yana Pikman, MD, Alexandre Puissant, PhD, Gabriela Alexe, PhD, Andrew Furman, BA, Stacey Frumm, BA, Linda Ross, PhD, Liying Chen, PhD, Nina Fenouille, PhD, Christopher F. Bassil, BA, Caroline A Lewis, PhD, Richard M. Stone, MD, Daniel J. DeAngelo, MD PhD, Ilene Galinsky, ANP, Andrew L Kung, MD PhD, Matthew Vader Heiden, MD PhD, Michael T. Hemann, PhD, Versha Banerji, MD, Kimberly Stegmaier, MD
Journal: Blood
Blood (2015) 126 (23): 443.
https://doi.org/10.1182/blood.V126.23.443.443
Published: 2015
Journal Articles

Regulation Of Normal and Malignant Hoxa Gene Expression Through Higher H3K79 Methylated States

Free
Aniruddha J Deshpande, Ph.D, Liying Chen, Ph.D., Amit U. Sinha, PhD, Nan Zhu, PhD, David Chen, Ph.D., Jenny Chang, Andrei V. Krivtsov, PhD, Kathrin Bernt, MD, James E Bradner, MD, Scott A. Armstrong, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 2492.
https://doi.org/10.1182/blood.V122.21.2492.2492
Published: 2013
Journal Articles

Targeting Folate Metabolism In Acute Myelogenous Leukemia

Free
Yana Pikman, MD, Alexandre Puissant, PhD, Gabriela Alexe, PhD, Stacey M. Frumm, Linda Ross, PhD, Liying Chen, Ph.D., Nina Fenouille, PhD, Christopher F Bassil, Clary B. Clish, PhD, Andrew L Kung, MD, PhD, Michael T Hemann, PhD, Versha Banerji, MD, Kimberly Stegmaier, MD
Journal: Blood
Blood (2013) 122 (21): 3798.
https://doi.org/10.1182/blood.V122.21.3798.3798
Published: 2013
Journal Articles

Leukemic transformation by the MLL-AF6 fusion oncogene requires the H3K79 methyltransferase Dot1l

Free
Aniruddha J. Deshpande, Liying Chen, Maurizio Fazio, Amit U. Sinha, Kathrin M. Bernt, Deepti Banka, Stuart Dias, Jenny Chang, Edward J. Olhava, Scott R. Daigle, Victoria M. Richon, Roy M. Pollock, Scott A. Armstrong
Journal: Blood
Blood (2013) 121 (13): 2533–2541.
https://doi.org/10.1182/blood-2012-11-465120
Published: 2013
Includes: Supplemental data
Journal Articles

MLL-AF6 Mediated Transformation Is Dependent On the H3K79 Methyl-transferase Dot1l

Free
Aniruddha J Deshpande, Liying Chen, Maurizio Fazio, Amit U. Sinha, Kathrin M Bernt, MD, Deepti Banka, Stuart Dias, Edward J Olhava, PhD, Scott R Daigle, Victoria M Richon, PhD, Roy M Pollock, PhD, Scott A. Armstrong, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 3502.
https://doi.org/10.1182/blood.V120.21.3502.3502
Published: 2012
Journal Articles

The Interaction Between DOT1L and AF10 Is Required for H3K79 Dimethylation and MLL-AF9 Leukemia

Free
Aniruddha J Deshpande, Liying Chen, Kathrin M Bernt, MD, Stuart Dias, Deepti Banka, Amit U. Sinha, David Chen, Natalie Punt, James E. Bradner, M.D., Scott A. Armstrong, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 401.
https://doi.org/10.1182/blood.V120.21.401.401
Published: 2012
Journal Articles

Abrogation of MLL-AF10 and CALM-AF10 Mediated Transformation Through Genetic Inactivation or Pharmacological Inhibition of the H3K79 Methyltransferase DOT1L.

Free
Liying Chen, Aniruddha J Deshpande, Deepti Banka, Bernt Kathrin, Stuart Dias, Christian Buske, MD, Edward J Olhava, PhD, Scott R Daigle, Victoria M Richon, PhD, Roy M Pollock, PhD, Scott A. Armstrong, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 2384.
https://doi.org/10.1182/blood.V120.21.2384.2384
Published: 2012