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Lisa Rohrbacher
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Journal Articles

CSF1R Targeting T Cell Engaging Bispecific Antibodies Enable Safe and Efficient Immunotherapies in Acute Myeloid Leukemia

Free
Gordon Victor Hoffmann, Adrian Gottschlich, Johannes Sam, Samuel Gebhardt, Lisa Rohrbacher, Sayantan Nandi, Emanuele Carlini, Tobias Herold, Michael von Bergwelt-Baildon, Stefan Endres, Marion Subklewe, Peter Bruenker, Christian Klein, Sebastian Kobold
Journal: Blood
Blood (2024) 144 (Supplement 1): 918.
https://doi.org/10.1182/blood-2024-207376
Published: 2024
Journal Articles

CD33-TIM3 Dual CAR T Cells: Enhancing Specificity While Maintaining Efficacy Against AML

Free
Yingshuai Wang, Wenjie Lu, Lisa Rohrbacher, Heinrich Flaswinkel, Alica Joana Emhardt, Giulia Magno, Sascha Haubner, Sebastian Kobold, Heinrich Leonhardt, Karl-Peter Hopfner, Dirk H Busch, Veit L. Buecklein, Daniel Nixdorf, Marion Subklewe
Journal: Blood
Blood (2023) 142 (Supplement 1): 3449.
https://doi.org/10.1182/blood-2023-180890
Published: 2023
Journal Articles

Two Players, One Goal: BiTE ® Vs CART Targeting FLT3 in AML

Free
Lisa Rohrbacher, Daniel Nixdorf, Helena Stadler, Bettina Brauchle, Florian Märkl, Nora Philipp, Gerulf Hänel, Anetta Marcinek, Maryam Kazerani, Alica Joana Emhardt, Giulia Magno, Rebecca L. Goldstein, Tobias Straub, Sebastian Kobold, Tara L. Chapman-Arvedson, Veit L. Buecklein, Marion Subklewe
Journal: Blood
Blood (2023) 142 (Supplement 1): 3444.
https://doi.org/10.1182/blood-2023-177922
Published: 2023
Journal Articles

Beyond Mitigating Immune-Related Adverse Events: Glucocorticoids Ameliorate Bispecific Antibody-Mediated T-Cell Exhaustion I n Vitro

Free
Amelie Muth, Nora Philipp, Anetta Marcinek, Tobias Straub, Lis Winter, Gerulf Hänel, Daniel Nixdorf, Lisa Rohrbacher, Veit L. Buecklein, Marion Subklewe
Journal: Blood
Blood (2023) 142 (Supplement 1): 5389.
https://doi.org/10.1182/blood-2023-174258
Published: 2023
Journal Articles

Adaptor Anti-P329G CAR T Cells for Modular Targeting of AML

Free
Sophia Stock, Thaddaeus Strzalkowski, Adrian Gottschlich, Lisa Rohrbacher, Luisa Fertig, Vivien D. Menkhoff, Marlena Surowka, Peter Bruenker, Diana Darowski, Stefan Endres, Michael von Bergwelt-Baildon, Marion Subklewe, Christian Klein, Sebastian Kobold
Journal: Blood
Blood (2023) 142 (Supplement 1): 4805.
https://doi.org/10.1182/blood-2023-182864
Published: 2023
Journal Articles

Targeting FLT3 with a new-generation antibody-drug conjugate in combination with kinase inhibitors for treatment of AML

Free
Maike Roas, Binje Vick, Marc-André Kasper, Marina Able, Harald Polzer, Marcus Gerlach, Elisabeth Kremmer, Judith S. Hecker, Saskia Schmitt, Andreas Stengl, Verena Waller, Natascha Hohmann, Moreno Festini, Alexander Ludwig, Lisa Rohrbacher, Tobias Herold, Marion Subklewe, Katharina S. Götze, Christian P. R. Hackenberger, Dominik Schumacher, Jonas Helma-Smets, Irmela Jeremias, Heinrich Leonhardt, Karsten Spiekermann
Journal: Blood
Blood (2023) 141 (9): 1023–1035.
https://doi.org/10.1182/blood.2021015246
Published: 2023
Includes: Supplemental data
Journal Articles

Uncovering the Enemy: Single-Cell Transcriptional Profiling of Measurable Residual Disease (MRD) Cells

Free
Maryam Kazerani, Lucas Wange, Benjamin Tast, Maria Solovey, Daniel Nixdorf, Lisa Rohrbacher, Christina Heitmüller, Thomas Koehnke, Frauke Schnorfeil, Victoria V Grunwald, Karsten Spiekermann, Klaus H. Metzeler, Karl-Peter Hopfner, Wolfgang Enard, Veit L Buecklein, Marion Subklewe
Journal: Blood
Blood (2022) 140 (Supplement 1): 6321–6322.
https://doi.org/10.1182/blood-2022-167788
Published: 2022
Journal Articles

The Race Is on: BiTE Vs CART As FLT3-Directed Immunotherapies in AML

Free
Lisa Rohrbacher, Daniel Nixdorf, Helena Stadler, Bettina Brauchle, Florian Märkl, Nora Phillip, Gerulf Hänel, Anetta Marcinek, Maryam Kazerani, Rebecca Goldstein, Michael von Bergwelt, Sebastian Kobold, Veit L Buecklein, Tara Chapman-Arvedson, Marion Subklewe
Journal: Blood
Blood (2022) 140 (Supplement 1): 10233–10234.
https://doi.org/10.1182/blood-2022-158452
Published: 2022
Journal Articles

T-cell exhaustion induced by continuous bispecific molecule exposure is ameliorated by treatment-free intervals

Open Access
Nora Philipp, Maryam Kazerani, Alyssa Nicholls, Binje Vick, Jan Wulf, Tobias Straub, Michaela Scheurer, Amelie Muth, Gerulf Hänel, Daniel Nixdorf, Monika Sponheimer, Malte Ohlmeyer, Sonja M. Lacher, Bettina Brauchle, Anetta Marcinek, Lisa Rohrbacher, Alexandra Leutbecher, Kai Rejeski, Oliver Weigert, Michael von Bergwelt-Baildon, Sebastian Theurich, Roman Kischel, Irmela Jeremias, Veit Bücklein, Marion Subklewe
Journal: Blood
Blood (2022) 140 (10): 1104–1118.
https://doi.org/10.1182/blood.2022015956
Published: 2022
Includes: Supplemental data
Journal Articles

Treatment-Free Intervals during CD19xCD3 BiTE ® Construct-Mediated T-Cell Stimulation Induce Functional Reinvigoration and Transcriptional Reprogramming of Exhausted T Cells

Free
Nora Zieger, Maryam Kazerani Pasikhani, Tobias Straub, Alyssa Nicholls, Gerulf Hänel, Jan Wulf, Michaela Scheurer, Daniel Nixdorf, Monika Sponheimer, Sonja M Lacher, Bettina Brauchle, Anetta Marcinek, Lisa Rohrbacher, Alexandra Leutbecher, Michael von Bergwelt, Karsten Spiekermann, Oliver Weigert, Sebastian Theurich, Veit L Buecklein, Roman Kischel, Marion Subklewe
Journal: Blood
Blood (2021) 138 (Supplement 1): 513.
https://doi.org/10.1182/blood-2021-150178
Published: 2021
Journal Articles

Treatment-Free Intervals Mitigate T-Cell Exhaustion Induced By Continuous CD19xCD3-BiTE® Construct Stimulation in Vitro

Free
Nora Zieger, Alyssa Nicholls, Jan Wulf, Gerulf Hänel, Maryam Kazerani Pasikhani, Veit Buecklein, MD, Bettina Brauchle, Anetta Marcinek, Daniel Nixdorf, Lisa Rohrbacher, Michaela Scheurer, Roman Kischel, MD, Karsten Spiekermann, MD, Oliver Weigert, MD, Sebastian Theurich, MD, Michael von Bergwelt, MD PhD, Marion Subklewe, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 44–45.
https://doi.org/10.1182/blood-2020-137421
Published: 2020