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Journal Articles

Enhanced Thrombotic Susceptibility, Endotheliopathy, and Abnormal Cognitive Behavior for up to 5 Months after Sars-Cov-2 Infection in a Mouse Model of Long COVID

Roberto Aiolfi, Antonella Zampolli, Miriam Hauer-Jensen, Jose A. Fernandez, Xiao Xu, Angel Gandarilla, Julia C.O. Mosnier, Amanda J. Roberts, Juan Carlos de la Torre, Laurent O. Mosnier

Blood (2024) 144 (Supplement 1): 1230.

https://doi.org/10.1182/blood-2024-212054

Published: 2024

Journal Articles

Heterobivalent Peptide Agonists Comprising Covalently Linked Protease Activated Receptor 1 and Protease Activated Receptor 3 Peptides Mimic the Cytoprotective Cell Signaling Activities of Activated Protein C

Jose A. Fernandez, Laura D. Healy, Laurent O. Mosnier, John H. Griffin

Blood (2023) 142 (Supplement 1): 3976.

https://doi.org/10.1182/blood-2023-185096

Published: 2023

Journal Articles

Survival Advantage Associated with Heterozygous Factor V Leiden Mutation in Sars-Cov-2-Infected K18-hACE2 Mice

Roberto Aiolfi, Jose A. Fernandez, Hiroshi Deguchi, Xiao Xu, Jeanine Ahmed, Miriam Hauer-Jensen, John H. Griffin, Juan Carlos de la Torre, Hartmut Weiler, Laurent O. Mosnier

Blood (2023) 142 (Supplement 1): 2563.

https://doi.org/10.1182/blood-2023-190742

Published: 2023

Journal Articles

Sex-Specific Differences in the Pathogenesis, Endothelial Dysfunction, and Hypercoagulability of Sars-Cov-2 Infection in K18-hACE2 Mice

Roberto Aiolfi, Hiroshi Deguchi, Jose F. Fernández, Jeanine Ahmed, Miriam Hauer-Jensen, Juan Carlos de la Torre, Laurent O. Mosnier

Blood (2022) 140 (Supplement 1): 1674–1675.

https://doi.org/10.1182/blood-2022-163863

Published: 2022

Journal Articles

Parmodulin, an Allosteric Inhibitor of Protease Activated Receptor 1 (PAR1) Protects Sickle Cell Mice from Thromboinflammation and Endothelial Dysfunction

Nirupama Ramadas, Kailyn Lowder, Laurent O. Mosnier, Rafal Pawlinski, Erica Sparkenbaugh

Blood (2022) 140 (Supplement 1): 5389–5390.

https://doi.org/10.1182/blood-2022-166708

Published: 2022

Journal Articles

Selective Modulation of Activated Protein C Activities By an Exosite-Specific Nanobody Library

Derek S Sim, Meenal Shukla, Cornell R Mallari, Doug Schneider, Maxine Bauzon, Terry W Hermiston, Laurent O. Mosnier

Blood (2022) 140 (Supplement 1): 973–974.

https://doi.org/10.1182/blood-2022-158855

Published: 2022

Journal Articles

Sars-Cov-2 Infection Promotes Endothelial Dysfunction and Thrombosis in a Mouse Model of COVID-19

Roberto Aiolfi, Jeanine Ahmed, Juan Carlos de la Torre, John H. Griffin, Laurent O. Mosnier

Blood (2021) 138 (Supplement 1): 999.

https://doi.org/10.1182/blood-2021-148713

Published: 2021

Journal Articles

Biased PAR-1 Signaling Regulates Thrombo-Inflammation in a Mouse Model of Sickle Cell Disease

Erica Sparkenbaugh, PhD, John H. Griffin, PhD, Laurent O Mosnier, Rafal Pawlinski, PhD

Blood (2020) 136 (Supplement 1): 16–17.

https://doi.org/10.1182/blood-2020-139862

Published: 2020

Journal Articles

How much clotting is enough?

Laurent O. Mosnier

Blood (2020) 136 (6): 651–652.

https://doi.org/10.1182/blood.2020006443

Published: 2020

Journal Articles

Super factor Va, an Engineered Factor V Molecule, Effectively Reduces Bleeding and Acute Coagulopathy in Mouse Models of Trauma and Shock

Bilgimol Chumappumkal Joseph, PhD, Laurent O Mosnier, Annette von Drygalski, MD PharmD

Blood (2019) 134 (Supplement_1): 1101.

https://doi.org/10.1182/blood-2019-124433

Published: 2019

Journal Articles

Cardiac Myosin Acts Is a Potent Procoagulant in Vitro and In Vivo

Jevgenia Zilberman-Rudenko, Hiroshi Deguchi, MD PhD, Mohammed Hayat, Meenal Shukla, PhD, Jennifer Nagrampa Orje, Zihan Guo, Tine Wyseure, PhD, Laurent O Mosnier, Owen J T McCarty, PhD, Zaverio M. Ruggeri, MD, John H. Griffin, PhD

Blood (2019) 134 (Supplement_1): 3632.

https://doi.org/10.1182/blood-2019-129312

Published: 2019

Journal Articles

Prevention of Bleeding-Induced Vascular Abnormalities in the Hemophilic Mouse Joint By Increasing TAFI Levels or Inhibiting uPA Activity

Tine Wyseure, PhD, Niels Behrendt, Annette von Drygalski, MD PharmD, Laurent O Mosnier

Blood (2019) 134 (Supplement_1): 158.

https://doi.org/10.1182/blood-2019-128723

Published: 2019

Journal Articles

Cerebral cavernous malformations form an anticoagulant vascular domain in humans and mice

Miguel Alejandro Lopez-Ramirez, Angela Pham, Romuald Girard, Tine Wyseure, Preston Hale, Atsuki Yamashita, Janne Koskimäki, Sean Polster, Laleh Saadat, Ignacio A. Romero, Charles T. Esmon, Frederic Lagarrigue, Issam A. Awad, Laurent O. Mosnier, Mark H. Ginsberg

Blood (2019) 133 (3): 193–204.

https://doi.org/10.1182/blood-2018-06-856062

Published: 2019

Includes: Supplemental data

Journal Articles

Systemic Transcriptional Responses to Hemarthrosis and FVIII Replacement in FVIII-Deficient Mice

Esther J Cooke, Srila Gopal, John Shimashita, Chanond A Nasamran, Kathleen M Fisch, Laurent O Mosnier, Annette von Drygalski

Blood (2018) 132 (Supplement 1): 381.

https://doi.org/10.1182/blood-2018-99-120092

Published: 2018

Journal Articles

Effects of Hemostasis Correction on Vascular Remodeling and Synovial Gene Expression Changes in Mice after Induced Hemarthrosis

Esther J Cooke, Jenny Y Zhou, Tine Wyseure, Srila Gopal, John Shimashita, Chanond A Nasamran, Kathleen M Fisch, Laurent O Mosnier, Annette von Drygalski

Blood (2018) 132 (Supplement 1): 1188.

https://doi.org/10.1182/blood-2018-99-119694

Published: 2018

Journal Articles

Defective TAFI activation in hemophilia A mice is a major contributor to joint bleeding

Tine Wyseure, Esther J. Cooke, Paul J. Declerck, Niels Behrendt, Joost C. M. Meijers, Annette von Drygalski, Laurent O. Mosnier

Blood (2018) 132 (15): 1593–1603.

https://doi.org/10.1182/blood-2018-01-828434

Published: 2018

Includes: Supplemental data

Journal Articles

Activated protein C, protease activated receptor 1, and neuroprotection

John H. Griffin, Berislav V. Zlokovic, Laurent O. Mosnier

Blood (2018) 132 (2): 159–169.

https://doi.org/10.1182/blood-2018-02-769026

Published: 2018

Journal Articles

Warfarin, a juggler’s demise

Laurent O. Mosnier

Blood (2018) 131 (25): 2742–2743.

https://doi.org/10.1182/blood-2018-05-843151

Published: 2018

Journal Articles

PAR1 biased signaling is required for activated protein C in vivo benefits in sepsis and stroke

Ranjeet K. Sinha, Yaoming Wang, Zhen Zhao, Xiao Xu, Laurent Burnier, Naveen Gupta, José A. Fernández, Greg Martin, Sergey Kupriyanov, Laurent O. Mosnier, Berislav V. Zlokovic, John H. Griffin

Blood (2018) 131 (11): 1163–1171.

https://doi.org/10.1182/blood-2017-10-810895

Published: 2018

Includes: Supplemental data

Journal Articles

The CXCL12/CXCR4 and VEGF165/Nrp1 Pathways Have Differential Effects on Pathological Neo-Angiogenesis and Vascular Remodeling in Hemophilic Arthropathy

Tine L. Wyseure, PhD, Esther J. Cooke, PhD, Annette von Drygalski, MD, Laurent O. Mosnier, PhD

Blood (2017) 130 (Supplement 1): 180.

https://doi.org/10.1182/blood.V130.Suppl_1.180.180

Published: 2017

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Enhanced Thrombotic Susceptibility, Endotheliopathy, and Abnormal Cognitive Behavior for up to 5 Months after Sars-Cov-2 Infection in a Mouse Model of Long COVID

Heterobivalent Peptide Agonists Comprising Covalently Linked Protease Activated Receptor 1 and Protease Activated Receptor 3 Peptides Mimic the Cytoprotective Cell Signaling Activities of Activated Protein C

Survival Advantage Associated with Heterozygous Factor V Leiden Mutation in Sars-Cov-2-Infected K18-hACE2 Mice

Sex-Specific Differences in the Pathogenesis, Endothelial Dysfunction, and Hypercoagulability of Sars-Cov-2 Infection in K18-hACE2 Mice

Parmodulin, an Allosteric Inhibitor of Protease Activated Receptor 1 (PAR1) Protects Sickle Cell Mice from Thromboinflammation and Endothelial Dysfunction

Selective Modulation of Activated Protein C Activities By an Exosite-Specific Nanobody Library

Sars-Cov-2 Infection Promotes Endothelial Dysfunction and Thrombosis in a Mouse Model of COVID-19

Biased PAR-1 Signaling Regulates Thrombo-Inflammation in a Mouse Model of Sickle Cell Disease

How much clotting is enough?

Super factor Va, an Engineered Factor V Molecule, Effectively Reduces Bleeding and Acute Coagulopathy in Mouse Models of Trauma and Shock

Cardiac Myosin Acts Is a Potent Procoagulant in Vitro and In Vivo

Prevention of Bleeding-Induced Vascular Abnormalities in the Hemophilic Mouse Joint By Increasing TAFI Levels or Inhibiting uPA Activity

Cerebral cavernous malformations form an anticoagulant vascular domain in humans and mice

Systemic Transcriptional Responses to Hemarthrosis and FVIII Replacement in FVIII-Deficient Mice

Effects of Hemostasis Correction on Vascular Remodeling and Synovial Gene Expression Changes in Mice after Induced Hemarthrosis

Defective TAFI activation in hemophilia A mice is a major contributor to joint bleeding

Activated protein C, protease activated receptor 1, and neuroprotection

Warfarin, a juggler’s demise

PAR1 biased signaling is required for activated protein C in vivo benefits in sepsis and stroke

The CXCL12/CXCR4 and VEGF165/Nrp1 Pathways Have Differential Effects on Pathological Neo-Angiogenesis and Vascular Remodeling in Hemophilic Arthropathy

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