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Koji Eto, MD
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Journal Articles

Harnessing a Novel Dyrk1a-Ablim2-MKL1 Regulatory Module in Megakaryocyte Morphogenesis to Enable Scalable Platelet "Pharming"

Free
Kamaleldin E Elagib, PhDMBBS, Ashton Brock, PhD, Goar Mosoyan, Cara Clementelli, Lorrie L Delehanty, BS, Alexandra Pacheco-Benichou, Corinne Fruit, Thierry Besson, PhD, Stephen Morris, MD, Koji Eto, MD, Camelia Iancu-Rubin, PhD, Adam N Goldfarb, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3250.
https://doi.org/10.1182/blood-2019-129049
Published: 2019
Journal Articles

Disease Model of Atherosclerosis Using Werner Syndrome Patient-Derived Induced Pluripotent Stem Cells Reveals Excessive Inflammatory Response Against Ox-LDL

Free
Sudip Kumar Paul, MSc, Masamitsu Sone, PhD, Hisaya Kato, MD PhD, Yoshiro Maezawa, MD PhD, Yasuo Ouchi, PhD, Koutaro Yokote, MD PhD, Koji Eto, MD, Naoya Takayama, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3615.
https://doi.org/10.1182/blood-2019-123919
Published: 2019
Journal Articles

Ex vivo Engineering of Platelets

Free
Koji Eto, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): SCI-6.
https://doi.org/10.1182/blood-2019-121116
Published: 2019
Journal Articles

Environmental Cell-Matrix Adhesion Modulates Pluripotent Stem Cell Fate Toward Definitive Hemogenic Endothelium and Hematopoietic Progenitor Cells

Free
Akinori Yuzuriha, Sou Nakamura, PhD, Toshie Kusunoki, Takuya Matsumoto, PhD, Naoshi Sugimoto, MD PhD, Kiyotoshi Sekiguchi, PhD, Koji Eto, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3845.
https://doi.org/10.1182/blood-2018-99-114505
Published: 2018
Journal Articles

Anagrelide Inhibits Proliferation and Platelet Generation in Immortalized Megakaryocyte Progenitor Cell Lines Established from Human Induced Pluripotent Stem Cells

Free
Koji Takaishi, MD, Masahiro Takeuchi, MD PhD, Shokichi Tsukamoto, MD PhD, Naoya Takayama, MD PhD, Motohiko Oshima, PhD, Yusuke Isshiki, MD, Kensuke Kayamori, MD, Kenji Kimura, MD, Yutaro Hino, MD, Nagisa Oshima-Hasegawa, MD PhD, Shio Mitsukawa, MD PhD, Yusuke Takeda, MD PhD, Naoya Mimura, MD PhD, Chikako Ohwada, MD PhD, Tohru Iseki, MD PhD, Sou Nakamura, PhD, Koji Eto, MD PhD, Atsushi Iwama, MD PhD, Koutaro Yokote, MD PhD, Chiaki Nakaseko, MDPhD, Emiko Sakaida, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1789.
https://doi.org/10.1182/blood-2018-99-111683
Published: 2018
Journal Articles

Synthetic miRNA Switch Technology Elucidates Heterogeneity in Regulation of Immortalized Megakaryocyte Cell Lines, Associated with Improvement of Platelet Generation Efficiency for Clinical Use

Free
Kazuya Hashimoto, Satoshi Matsuura, Yoshihiko Fujita, Karin Hayashi, Naoshi Sugimoto, MD PhD, Takuya Yamamoto, Hirohide Saito, Koji Eto, MD PhD
Journal: Blood
Blood (2016) 128 (22): 3867.
https://doi.org/10.1182/blood.V128.22.3867.3867
Published: 2016
Journal Articles

Natural Killer Cell Activities Against iPSCs-Derived HLA-Knockout Platelets and Megakaryocytes Reveal Perfect Rejection Profiles for Allotransfusion

Free
Daisuke Suzuki, Naoshi Sugimoto, MD PhD, Norihide Yoshikawa, Hiroshi Endo, Sou Nakamura, Akitsu Hotta, Koji Eto, MD PhD
Journal: Blood
Blood (2016) 128 (22): 3841.
https://doi.org/10.1182/blood.V128.22.3841.3841
Published: 2016
Journal Articles

A Novel Chemical Approach to Expand Platelets Using Immortalized Megakaryocyte Progenitor Cells Derived from Human Induced Pluripotent Stem Cells

Free
Ayako Otani, Tomo Koike, Natsuki Abe, Takanori Nakamura, PhD, Taito Nishino, PhD, Hiromitsu Nakauchi, MD PhD, Koji Eto, MD, PhD
Journal: Blood
Blood (2014) 124 (21): 3845.
https://doi.org/10.1182/blood.V124.21.3845.3845
Published: 2014
Journal Articles

The Cytokine Signal Inhibitor Lnk Promotes αIIbβ3 Integrin Outside-In Signaling through β3 Tyrosine Phosphorylation in Platelets.

Free
Koji Eto, MD, PhD, Hitoshi Takizawa, Ph.D., Satoshi Takaki, M.D., Ph.D., Hidekazu Nishikii, M.D., Atsushi Oda, M.D., Ph.D., Hiromitsu Nakauchi, M.D., Ph.D.
Journal: Blood
Blood (2007) 110 (11): 3651.
https://doi.org/10.1182/blood.V110.11.3651.3651
Published: 2007
Journal Articles

Metalloproteinase Regulation Determines Integrin αIIbβ3 Function and Enhances the Capacity of ES Cell-Derived Platelets.

Free
Hidekazu Nishikii, MD, Koji Eto, MD, Taisuke Kanaji, MD, Jerry Ware, PhD, Hiromitsu Nakauchi, MD, PhD
Journal: Blood
Blood (2006) 108 (11): 140.
https://doi.org/10.1182/blood.V108.11.140.140
Published: 2006
Journal Articles

Human Embryonic Stem Cell-Derived “NET-Like” Structure Serves as a Hematopoietic Progenitor Niche and Favors Generation of Mature Megakaryocytes and Functional Platelets.

Free
Naoya Takayama, MD, Hidekazu Nishikii, MD, Takashi Hiroyama, PhD, Yukio Nakamura, MD, PhD, Hiroko Tsukui, Koji Eto, MD, Hiromitsu Nakauchi, MD, PhD
Journal: Blood
Blood (2006) 108 (11): 1665.
https://doi.org/10.1182/blood.V108.11.1665.1665
Published: 2006
Journal Articles

Negative Hematopoietic Scaffold Lnk Upregulates Integrin Outside-In Signaling in Platelets.

Free
Koji Eto, MD, Hitoshi Takizawa, Hidekazu Nishikii, MD, Jun Seita, MD, Atsushi Oda, MD, Noriko Tamura, PhD, Shinya Goto, MD, Kiyoshi Takatsu, PhD, Satoshi Takaki, MD, Hiromitsu Nakauchi, MD
Journal: Blood
Blood (2005) 106 (11): 382.
https://doi.org/10.1182/blood.V106.11.382.382
Published: 2005