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Journal Articles

PSTK inhibition activates cGAS-STING, precipitating ferroptotic cell death in leukemic stem cells

Lingli He, Ting Zhao, Wei Zhong Leong, Azeem Sharda, Christina Mayerhofer, Shenglin Mei, Gracia M. Bonilla, Juan Bautista Menendez-Gonzalez, Karin Gustafsson, Tsuyoshi Fukushima, Trine A. Kristiansen, Ji-Won Lee, Yanxin Xu, Lei Chen, Jun Xia, Luis Angel Orozco, Bogdan Budnik, Ruslan Sadreyev, Zhixun Dou, David B. Sykes, David T. Scadden
Journal: Blood
Blood (2025) 145 (17): 1903–1914.
https://doi.org/10.1182/blood.2024026040
Published: 2025
Includes: Supplemental data
Journal Articles

Cancer Versus Cardiac Mortality Risk with Adult Thymectomy

Kameron Allen Kooshesh, Brody Foy, Richard Baylis, Karin Gustafsson, Daniel Zlotoff, Tomas Neilan, David Scadden
Journal: Blood
Blood (2024) 144 (Supplement 1): 121.
https://doi.org/10.1182/blood-2024-208804
Published: 2024
Journal Articles

Thymopoiesis-Associated Genetic Variant Correlates with Cancer Risk and Outcome

Kameron Allen Kooshesh, Karin Gustafsson, Brody Foy, David Scadden
Journal: Blood
Blood (2024) 144 (Supplement 1): 3920.
https://doi.org/10.1182/blood-2024-205972
Published: 2024
Journal Articles

Modulating mRNA Translation Fidelity As a Novel Mechanism for AML Chemoresistance

Christina Mayerhofer, Dan Li, Trine A. Kristiansen, Ernst Mayerhofer, Azeem Sharda, Lingli He, Michael Mazzola, Giulia Schiroli, Karin Gustafsson, Sam Keyes, Anna Kiem, Eve Crompton, Yanxin Xu, Zhixun Dou, Charles Vidoudez, Peter G. Miller, Nick Van Gastel, David Scadden
Journal: Blood
Blood (2024) 144 (Supplement 1): 2727.
https://doi.org/10.1182/blood-2024-205125
Published: 2024
Journal Articles

AML Stem Cell Clearance By Inhibiting Selenoprotein Biosynthesis That Causes Cgas-Sting Activation and Ferroptosis

Lingli He, Ting Zhao, Wei Zhong Leong, Azeem Sharda, Christina Mayerhofer, Shenglin Mei, Gracia M. Bonilla, Juan Bautista Menendez-Gonzalez, Karin Gustafsson, Tsuyoshi Fukushima, Trine A. Kristiansen, Ji-Won Lee, Yanxin Xu, Bogdan Budnik, Ruslan Sadreyev, Zhixun Dou, David B. Sykes, David Scadden
Journal: Blood
Blood (2024) 144 (Supplement 1): 1354.
https://doi.org/10.1182/blood-2024-211314
Published: 2024
Journal Articles

The Thymus Is Critical for Adult Immune Function

Kameron Kooshesh, Karin Gustafsson, Brody Foy, David Sykes, David T. Scadden
Journal: Blood
Blood (2022) 140 (Supplement 1): 1648–1649.
https://doi.org/10.1182/blood-2022-170925
Published: 2022
Journal Articles

Cap-Independent Protein Translation in Hematopoiesis

Michael Mazzola, Ting Zhao, Karin Gustafsson, Trine Kristiansen, Giulia Schiroli, Jelena Milosevic, Youmna Kfoury, Tsuyoshi Fukushima, Anna Kiem, Azeem Sharda, Hiroki Kato, David Sykes, Pavel Ivanov, Vijay G. Sankaran, David T. Scadden
Journal: Blood
Blood (2022) 140 (Supplement 1): 1983–1984.
https://doi.org/10.1182/blood-2022-170506
Published: 2022
Journal Articles

Spatial Transcriptomics Reveals DPP4 As Novel Marker of a More Proliferative Phenotype in Early AML Progression

Christa Haase, Karin Gustafsson, Shenglin Mei, Jelena Milosevic, Shu-Chi Yeh, David Sykes, Peter Kharchenko, David T. Scadden, Charles Lin
Journal: Blood
Blood (2021) 138 (Supplement 1): 3310.
https://doi.org/10.1182/blood-2021-151917
Published: 2021
Journal Articles

Reversing Clonal Hematopoiesis and Associated Atherosclerotic Disease By Targeted Antibody-Drug-Conjugate (ADC) Conditioning and Transplant

Karin Gustafsson, PhD, Catherine S Rhee, PhD, Elizabeth W Scadden, Vanessa Frodermann, Rahul Palchaudhuri, PhD, Sharon L. Hyzy, MS, Jennifer L Proctor, BS, Geoff O Gillard, PhD, Anthony E Boitano, PhD, Michael P. Cooke, PhD, Matthias Nahrendorf, PhD, David T. Scadden, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 34–35.
https://doi.org/10.1182/blood-2020-143176
Published: 2020
Journal Articles

Thymus Regeneration Is Dependent on Distinct Mesenchymal Stromal Cell Populations

Karin Gustafsson, PhD, Nikolas Barkas, PhD, Ninib Baryawno, PhD, Elizabeth W Scadden, Nicolas Severe, PhD, Joel A Spencer, PhD, Hayalneh Gessessew, Kameron Kooshesh, Jimin Guo, PhD, Charles Lin, PhD, Peter Kharchenko, PhD, David T. Scadden, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 586.
https://doi.org/10.1182/blood-2019-126708
Published: 2019
Journal Articles

Distinct Stress Responses of Bone Marrow Stromal Cell Subgroups Defined by Unbiased Single-Cell Mass-Cytometry Analysis

Nicolas Severe, PhD, Murat Karabacak, PhD, Ninib Baryawno, PhD, Karin Gustafsson, PhD, Youmna Sami Kfoury, PhD, Mehmet Toner, PhD, David T. Scadden, MD
Journal: Blood
Blood (2016) 128 (22): 430.
https://doi.org/10.1182/blood.V128.22.430.430
Published: 2016
Journal Articles

Identification and characterization of VEGF-A–responsive neutrophils expressing CD49d, VEGFR1, and CXCR4 in mice and humans

Sara Massena, Gustaf Christoffersson, Evelina Vågesjö, Cédric Seignez, Karin Gustafsson, François Binet, Carmen Herrera Hidalgo, Antoine Giraud, Jalal Lomei, Simone Weström, Masabumi Shibuya, Lena Claesson-Welsh, Pär Gerwins, Michael Welsh, Johan Kreuger, Mia Phillipson
Journal: Blood
Blood (2015) 126 (17): 2016–2026.
https://doi.org/10.1182/blood-2015-03-631572
Published: 2015
Includes: Supplemental data