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Journal Articles

Transfer of mRNA Encoding CEBPA in Lipid Nanoparticles to CEBPA Mutated Leukemia Cell Line KO52 and Primary AML Reduces Cell Growth and Induces Myeloid Differentiation

Chunxiao Zhang, Brenda Loera, Jianying Zhang, Richard Gelinas, Youmna Kfoury, Jonathan Hoggatt, Guido Marcucci, Pamela S. Becker

Blood (2023) 142 (Supplement 1): 7122.

https://doi.org/10.1182/blood-2023-190191

Published: 2023

Journal Articles

Rapid and Robust Mobilization of CD34+ HSCs without G-CSF Following Administration of Mgta-145 Alone or in Combination with Plerixafor

John F. DiPersio, MD PhD, Jonathan Hoggatt, PhD, Steven Devine, MD, Lukasz Biernat, MD, Haley Howell, BS, BA, Veit Schmelmer, PhD, Jason R. Neale, PhD, Anthony E. Boitano, PhD, Michael P. Cooke, PhD, Kevin A. Goncalves, PhD, Glen D. Raffel, MD PhD, Patrick C. Falahee, PhD, Dwight M. Morrow, PhD, John C. Davis, Jr., MD MPH, MS

Blood (2019) 134 (Supplement_1): 1961.

https://doi.org/10.1182/blood-2019-127523

Published: 2019

Journal Articles

The Combination of GROβ and AMD3100 Leads to Rapid and Robust Mobilization of Hematopoietic Stem Cells in Nonhuman Primates

Patrick C. Falahee, PhD, Kevin A. Goncalves, PhD, Sharon L. Hyzy, MS, Jennifer L. Proctor, BS, Jonathan Hoggatt, PhD, Dwight Morrow, PhD, Michael P. Cooke, PhD

Blood (2017) 130 (Supplement 1): 1920.

https://doi.org/10.1182/blood.V130.Suppl_1.1920.1920

Published: 2017

Journal Articles

Completely Non-Myeloablative/Non-Lymphoablative Conditioning for BMT/HSCT Using Anti-Ckit Immunotoxins

Agnieszka Czechowicz, MD PhD, Rahul Palchaudhuri, PhD, Amelia Scheck, BS, Jonathan Hoggatt, PhD, Borja Saez, PhD, David T. Scadden, MD, Derrick J. Rossi, PhD

Blood (2016) 128 (22): 493.

https://doi.org/10.1182/blood.V128.22.493.493

Published: 2016

Journal Articles

Rapid Mobilization Reveals a Highly Engraftable Hematopoietic Stem Cell

Jonathan Hoggatt, PhD, Pratibha Singh, PhD, Tiffany Tate, BS, Peter V. Kharchenko, PhD, Amir Schajnovitz, PhD, Ninib Barawnyo, PhD, Francois Mercier, MD, Dwight Morrow, PhD, David T. Scadden, MD, Louis M. Pelus, PhD

Blood (2016) 128 (22): 368.

https://doi.org/10.1182/blood.V128.22.368.368

Published: 2016

Journal Articles

Immunotoxin Enables Non-Genotoxic Conditioning for Hematopoietic Stem Cell Transplantation

Rahul Palchaudhuri, PhD, Borja Saez, PhD, Jonathan Hoggatt, PhD, Amir Schajnovitz, David B. Sykes, MD PhD, Michael K Mansour, MD PhD, David T. Scadden, MD

Blood (2015) 126 (23): 32.

https://doi.org/10.1182/blood.V126.23.32.32

Published: 2015

Journal Articles

Oncostatin M Enhances Hematopoietic Stem Cell Homing and Engraftment

Hannah K Rasmussen, Frankie Wong, BA, Tiffany Tate, BS, David T. Scadden, MD, Jonathan Hoggatt, PhD

Blood (2015) 126 (23): 31.

https://doi.org/10.1182/blood.V126.23.31.31

Published: 2015

Journal Articles

Embigin Regulates HSPC Homing and Quiescence and Acts As a Cell Surface Marker for a Niche Factor-Enriched Subset of Osteolineage Cells

Lev Silberstein, MDPhD, Peter V. Kharchenko, PhD, Youmna Sami Kfoury, PhD, Francois Mercier, MD FRCPC, Raphael Turcotte, Charles P. Lin, Ninib Baryawno, PhD, Nicolas Severe, Tiffany Tate, BS, Jonathan Hoggatt, PhD, David T. Scadden, MD

Blood (2015) 126 (23): 663.

https://doi.org/10.1182/blood.V126.23.663.663

Published: 2015

Journal Articles

Proximity-Based Single Cell Analysis of the Bone Marrow Niche Identifies Interleukin-18 As a Quiescence Regulator of Early Hematopoietic Progenitors

Lev Silberstein, MDPhD, Peter Kharchenko, PhD, Youmna Kfoury, PhD, Francois Mercier, MD, Masatake Osawa, PhD, Jonathan Hoggatt, PhD, Tiffany Tate, Charles Lin, PhD, David T. Scadden, MD

Blood (2014) 124 (21): 773.

https://doi.org/10.1182/blood.V124.21.773.773

Published: 2014

Journal Articles

Pharmacologic increase in HIF1α enhances hematopoietic stem and progenitor homing and engraftment

Jennifer M. Speth, Jonathan Hoggatt, Pratibha Singh, Louis M. Pelus

Blood (2014) 123 (2): 203–207.

https://doi.org/10.1182/blood-2013-07-516336

Published: 2014

Includes: Supplemental data

Journal Articles

Hif1α and Rac1 Are Necessary For Enhanced HSPC Migration and Homing In Response To Prostaglandin E 2 Treatment

Jennifer M. Speth, PhD, Maegan L. Capitano, Ph.D., Jonathan Hoggatt, PhD, Louis M. Pelus, PhD

Blood (2013) 122 (21): 889.

https://doi.org/10.1182/blood.V122.21.889.889

Published: 2013

Journal Articles

Bone Marrow Sinusoidal Integrity Regulates Hematopoietic Stem and Progenitor Cell Trafficking

Pratibha Singh, PhD, Khalid Mohammad, PhD, Jonathan Hoggatt, PhD, Jennifer M. Speth, PhD, Louis M. Pelus, PhD

Blood (2013) 122 (21): 3687.

https://doi.org/10.1182/blood.V122.21.3687.3687

Published: 2013

Journal Articles

Prostaglandin-modulated umbilical cord blood hematopoietic stem cell transplantation

Blood (2013) 122 (17): 3074–3081.

https://doi.org/10.1182/blood-2013-05-503177

Published: 2013

Includes: Supplemental data

Journal Articles

Prostaglandin E 2 enhances long-term repopulation but does not permanently alter inherent stem cell competitiveness

Jonathan Hoggatt, Khalid S. Mohammad, Pratibha Singh, Louis M. Pelus

Blood (2013) 122 (17): 2997–3000.

https://doi.org/10.1182/blood-2013-07-515288

Published: 2013

Journal Articles

Sinusoidal Endothelial CD26 Cleavage of Neuropeptide Y Regulates Transendothelial Migration and Mobilization of Hematopoietic Stem and Progenitor Cells in Response to G-CSF.

Pratibha Singh, PhD, Jonathan Hoggatt, Ph.D., Peirong Hu, PhD, Louis M. Pelus, PhD

Blood (2012) 120 (21): 2347.

https://doi.org/10.1182/blood.V120.21.2347.2347

Published: 2012

Journal Articles

Blockade of prostaglandin E 2 signaling through EP1 and EP3 receptors attenuates Flt3L-dependent dendritic cell development from hematopoietic progenitor cells

Pratibha Singh, Jonathan Hoggatt, Peirong Hu, Jennifer M. Speth, Seiji Fukuda, Richard M. Breyer, Louis M. Pelus

Blood (2012) 119 (7): 1671–1682.

https://doi.org/10.1182/blood-2011-03-342428

Published: 2012

Includes: Supplemental data

Journal Articles

Bone Marrow Niche Attenuation by Non-Steroidal Anti-Inflammatory Drugs Mobilizes Hematopoietic Stem and Progenitor Cells by Differing Mechanisms

Jonathan Hoggatt, Ph.D., Khalid S Mohammad, M.D. Ph.D., Brahmananda Reddy Chitteti, PhD, Pratibha Singh, PhD, Jennifer M Speth, Peirong Hu, PhD, Bradley Poteat, Edward Srour, PhD, Theresa Guise, M.D., Louis M. Pelus, PhD

Blood (2011) 118 (21): 724.

https://doi.org/10.1182/blood.V118.21.724.724

Published: 2011

Journal Articles

Enhanced Homing of HSPCs After Treatment with Prostaglandin E2 (PGE 2 ) May Be An Effect of Transcriptional Regulation of CXC Chemokine Receptor 4 (CXCR4) Through Hypoxia Inducible Factor 1α (HIF1α)

Jennifer M Speth, Jonathan Hoggatt, Ph.D., Louis M. Pelus, PhD

Blood (2011) 118 (21): 918.

https://doi.org/10.1182/blood.V118.21.918.918

Published: 2011

Journal Articles

Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) Alter the Hematopoietic Niche and Treatment In Healthy Volunteers Results In Mobilization of CD34 + Cells, Hematopoietic Colony Forming Cells, and Endothelial Colony Forming Cells

Jonathan Hoggatt, PhD, Brahmananda Reddy Chitteti, PhD, Vani Krishna, Ph.D., Sherif Farag, MD, PhD, FRACP, FRCPA, Magdalena Czader, MD, Mervin C. Yoder, MD, Edward Srour, PhD, Louis M. Pelus, PhD

Blood (2010) 116 (21): 556.

https://doi.org/10.1182/blood.V116.21.556.556

Published: 2010

Journal Articles

Survivin Modulates Gene Expression That Connects through An Extensive Functional Signaling Network and Regulates Proliferation of Hematopoietic Stem Cells through Evi-1

Seiji Fukuda, MD, PhD, Pratibha Singh, PhD, Jonathan Hoggatt, PhD, Jennifer Speth, MS, Mariko Abe, MD, Edward M. Conway, MD, PhD, FRCPC, MBA, John Crispino, PhD, Giuseppina Nucifora, Seiji Yamaguchi, MD, Louis M. Pelus, PhD

Blood (2010) 116 (21): 87.

https://doi.org/10.1182/blood.V116.21.87.87

Published: 2010

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Transfer of mRNA Encoding CEBPA in Lipid Nanoparticles to CEBPA Mutated Leukemia Cell Line KO52 and Primary AML Reduces Cell Growth and Induces Myeloid Differentiation

Rapid and Robust Mobilization of CD34+ HSCs without G-CSF Following Administration of Mgta-145 Alone or in Combination with Plerixafor

The Combination of GROβ and AMD3100 Leads to Rapid and Robust Mobilization of Hematopoietic Stem Cells in Nonhuman Primates

Completely Non-Myeloablative/Non-Lymphoablative Conditioning for BMT/HSCT Using Anti-Ckit Immunotoxins

Rapid Mobilization Reveals a Highly Engraftable Hematopoietic Stem Cell

Immunotoxin Enables Non-Genotoxic Conditioning for Hematopoietic Stem Cell Transplantation

Oncostatin M Enhances Hematopoietic Stem Cell Homing and Engraftment

Embigin Regulates HSPC Homing and Quiescence and Acts As a Cell Surface Marker for a Niche Factor-Enriched Subset of Osteolineage Cells

Proximity-Based Single Cell Analysis of the Bone Marrow Niche Identifies Interleukin-18 As a Quiescence Regulator of Early Hematopoietic Progenitors

Pharmacologic increase in HIF1α enhances hematopoietic stem and progenitor homing and engraftment

Hif1α and Rac1 Are Necessary For Enhanced HSPC Migration and Homing In Response To Prostaglandin E 2 Treatment

Bone Marrow Sinusoidal Integrity Regulates Hematopoietic Stem and Progenitor Cell Trafficking

Prostaglandin-modulated umbilical cord blood hematopoietic stem cell transplantation

Prostaglandin E 2 enhances long-term repopulation but does not permanently alter inherent stem cell competitiveness

Sinusoidal Endothelial CD26 Cleavage of Neuropeptide Y Regulates Transendothelial Migration and Mobilization of Hematopoietic Stem and Progenitor Cells in Response to G-CSF.

Blockade of prostaglandin E 2 signaling through EP1 and EP3 receptors attenuates Flt3L-dependent dendritic cell development from hematopoietic progenitor cells

Bone Marrow Niche Attenuation by Non-Steroidal Anti-Inflammatory Drugs Mobilizes Hematopoietic Stem and Progenitor Cells by Differing Mechanisms

Enhanced Homing of HSPCs After Treatment with Prostaglandin E2 (PGE 2 ) May Be An Effect of Transcriptional Regulation of CXC Chemokine Receptor 4 (CXCR4) Through Hypoxia Inducible Factor 1α (HIF1α)

Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) Alter the Hematopoietic Niche and Treatment In Healthy Volunteers Results In Mobilization of CD34 + Cells, Hematopoietic Colony Forming Cells, and Endothelial Colony Forming Cells

Survivin Modulates Gene Expression That Connects through An Extensive Functional Signaling Network and Regulates Proliferation of Hematopoietic Stem Cells through Evi-1

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