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Jill Durkin
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Journal Articles

PTPN12 Is Targetable and Context-Specific TSG in -7/del7q Myeloid Neoplasia

Free
Daniel J Vail, Jill Durkin, Dongxu Jiang, Thomas Laframboise, Babal K. Jha
Journal: Blood
Blood (2024) 144 (Supplement 1): 2756.
https://doi.org/10.1182/blood-2024-208538
Published: 2024
Journal Articles

TET2 Regulates Stability of Mismatch Repair Protein MSH6 and Helps Maintain Genomic Stability Independent of Its Dioxygenase Function

Free
Dongxu Jiang, Yahan Zhang, Xiaorong Gu, Daniel J Vail, Jill Durkin, Simon Schlanger, J. Joseph Melenhorst, Jaroslaw Maciejewski, Babal K. Jha
Journal: Blood
Blood (2024) 144 (Supplement 1): 40.
https://doi.org/10.1182/blood-2024-211171
Published: 2024
Journal Articles

Identification of Tumor Suppressors and Synthetic Lethal Targets in -7/del7q Myeloid Neoplasms By Iterative Computational Analysis Coupled with Experimental Validation

Free
Daniel J Vail, Valeria Visconte, Babal K. Jha, Jill Durkin, Jaroslaw Maciejewski, Thomas Laframboise
Journal: Blood
Blood (2024) 144 (Supplement 1): 4303.
https://doi.org/10.1182/blood-2024-210881
Published: 2024
Journal Articles

Rap Guanine Nucleotide Exchange Factor RAPGEF5 Is a Novel Tumor Suppressor in 7/del7q Myeloid Neoplasia

Free
Jill Durkin, Daniel Vail, Dongxu Jiang, Yahan Zhang, Simon Schlanger, Jaroslaw Maciejewski, Thomas Laframboise, Babal K. Jha
Journal: Blood
Blood (2024) 144 (Supplement 1): 5727.
https://doi.org/10.1182/blood-2024-207943
Published: 2024
Journal Articles

Developing a Therapeutic Strategy for Targeting Metabolic Vulnerability of TET2 Mutant Leukemia

Free
Xiaorong Gu, Yahan Zhang, Songa Bae, Dongxu Jiang, Nakisha D Williams, Daniel Vail, Simon Schlanger, Jill Durkin, Yvonne Parker, Daniel Lindner, Jaroslaw Maciejewski, Babal K. Jha
Journal: Blood
Blood (2024) 144 (Supplement 1): 2918.
https://doi.org/10.1182/blood-2024-207470
Published: 2024
Journal Articles

Fatty Acid Binding Protein FABP5 Inhibition Activates Retinoic Acid Signaling and Induces Differentiation in Acute Myeloid Leukemia

Free
Divya Jyoti Singh, Metis Hasipek, Dongxu Jiang, Daniel Vail, Yahan Zhang, Jill Durkin, Naomi Kawashima, Simon Schlanger, Xiaorong Gu, Jaroslaw P. Maciejewski, Yogenthiran Saunthararajah, Hetty E. Carraway, Babal Kant Jha
Journal: Blood
Blood (2023) 142 (Supplement 1): 1422.
https://doi.org/10.1182/blood-2023-189274
Published: 2023
Journal Articles

Metabolic Signatures and Pathway Rewiring in TET2-Mutated Myeloid Neoplasia

Free
Xiaorong Gu, Dongxu Jiang, Simon Schlanger, Nakisha D Williams, Divya Jyoti Singh, Daniel Vail, Jill Durkin, Yahan Zhang, Valeria Visconte, Jaroslaw P. Maciejewski, Babal Kant Jha
Journal: Blood
Blood (2023) 142 (Supplement 1): 2747.
https://doi.org/10.1182/blood-2023-189228
Published: 2023
Journal Articles

Methyl-CpG Binding Domain Protein MBD2 Is a Targetable Vulnerability in TET2 Mutant Myeloid Neoplasia

Free
Dongxu Jiang, Yihong Guan, Shinjini Ganguly, Aysegul Balyimez, Andrew Muskara, Divya Jyoti Singh, Simona Pagliuca, Daniel Vail, Yahan Zhang, Jill Durkin, Naomi Kawashima, Xiaorong Gu, Carmelo Gurnari, Jaroslaw P. Maciejewski, Omar Mian, Babal K. Jha
Journal: Blood
Blood (2023) 142 (Supplement 1): 2766.
https://doi.org/10.1182/blood-2023-186924
Published: 2023