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Jacob Nersting
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Journal Articles

Effects of germline DHFR and FPGS variants on methotrexate metabolism and relapse of leukemia

Morten Tulstrup, Takaya Moriyama, Chuang Jiang, Marie Grosjean, Jacob Nersting, Jonas Abrahamsson, Kathrine Grell, Lisa Lyngsie Hjalgrim, Ólafur Gísli Jónsson, Jukka Kanerva, Bendik Lund, Stine Nygaard Nielsen, Rikke Linnemann Nielsen, Ulrik Overgaard, Petter Quist-Paulsen, Kaie Pruunsild, Goda Vaitkeviciene, Benjamin Ole Wolthers, Hui Zhang, Ramneek Gupta, Jun J. Yang, Kjeld Schmiegelow
Journal: Blood
Blood (2020) 136 (10): 1161–1168.
https://doi.org/10.1182/blood.2020005064
Published: 2020
Includes: Supplemental data
Journal Articles

No Association between Relapse Risk and Thiopurine Methyltransferase Activity By Either Geno- or Phenotype in the NOPHO ALL-2008 Protocol

Stine Nygaard Nielsen, PhD MD, Kathrine Grell, PhD, Jacob Nersting, PhD, Jonas Abrahamsson, MD PhD, Bendik Lund, MD PhD, Jukka A. Kanerva, MD, Ólafur G Jónsson, MD, Goda Vaitkeviciene, MD, Kaie Pruunsild, MD, Malin Lindqvist Appell, Lisa Hjalgrim, PhD, Kjeld Schmiegelow, MD DMSc
Journal: Blood
Blood (2017) 130 (Supplement 1): 1279.
https://doi.org/10.1182/blood.V130.Suppl_1.1279.1279
Published: 2017
Journal Articles

Using Whole Exome Sequencing in Pediatric Acute Lymphoblastic Leukemia Germline, Diagnosis, and Relapse Trios to Discover Novel Relapse Enriched Mutations for Clonal Backtracking By Ddpcr

Jason Saliba, PhD, Nikki Ann Evensen, PhD BS, Julia Meyer, PhD, Igor Dolgalev, MS, Daniel Newman, BA, BSc, Ashfiyah Chowdhury, BSc, Jacob Nersting, PhD, Jinhua Wang, PhD, Kjeld Schmiegelow, MD DMSc, William L. Carroll, MD
Journal: Blood
Blood (2016) 128 (22): 4085.
https://doi.org/10.1182/blood.V128.22.4085.4085
Published: 2016
Journal Articles

Response: challenges and pitfalls in the mapping of the natural history of t(12;21)–positive childhood ALL

Kjeld Schmiegelow, Ulrik Lausten-Thomsen, Hans O. Madsen, Jacob Nersting, Henrik Hjalgrim
Journal: Blood
Blood (2011) 117 (1): 370–371.
https://doi.org/10.1182/blood-2010-10-310904
Published: 2011
Journal Articles

Prevalence of t(12;21)[ ETV6-RUNX1 ]–positive cells in healthy neonates

Clinical Trials & Observations
Ulrik Lausten-Thomsen, Hans Ole Madsen, Therese Risom Vestergaard, Henrik Hjalgrim, Jacob Nersting, Kjeld Schmiegelow
Journal: Blood
Blood (2011) 117 (1): 186–189.
https://doi.org/10.1182/blood-2010-05-282764
Published: 2011
Journal Articles

Methotrexate/6-mercaptopurine maintenance therapy influences the risk of a second malignant neoplasm after childhood acute lymphoblastic leukemia: results from the NOPHO ALL-92 study

Clinical Trials & Observations
Kjeld Schmiegelow, Ibrahim Al-Modhwahi, Mette Klarskov Andersen, Mikael Behrendtz, Erik Forestier, Henrik Hasle, Mats Heyman, Jon Kristinsson, Jacob Nersting, Randi Nygaard, Anne Louise Svendsen, Kim Vettenranta, Richard Weinshilboum
Journal: Blood
Blood (2009) 113 (24): 6077–6084.
https://doi.org/10.1182/blood-2008-11-187880
Published: 2009
Journal Articles

Response: Could mutations in the hypoxanthine-guanine phosphoribosyl transferase gene induced by thiopurine therapy promote the development of second malignant neoplasms?

Kjeld Schmiegelow, Ibrahim Al-Modhawi, Mette Klarskov Andersen, Mikael Berendtz, Erik Forestier, Henrik Hasle, Mats Heyman, Jon Kristinsson, Jacob Nersting, Randi Nygaard, Anne Louise Svendsen, Kim Vettenranta, Richard Weinshilboum
Journal: Blood
Blood (2009) 113 (24): 6258–6259.
https://doi.org/10.1182/blood-2009-03-210195
Published: 2009