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Journal Articles

The ‘Stop TPO-Receptor Agonist in ITP Patients’ (STIP) Study: Clinical and Immune Modulatory Effects of Romiplostim Tapering

Vivianne S. Nelson, Sufia N. Amini, Tanja Netelenbos, Marina Kartachova, Roger EG Schutgens, Otto Visser, Peter E. Westerweel, Jaap Jan Zwaginga, Suzanne Hofstede-Van Egmond, Rick Kapur, Masja De Haas, Leendert Porcelijn, Martin R. Schipperus

Blood (2024) 144 (Supplement 1): 2554.

https://doi.org/10.1182/blood-2024-203223

Published: 2024

Journal Articles

Randomized Trial of Prophylactic Donor Lymphocyte Infusion with Positively Selected CD4+ T Cells after HLA-Identical Allogeneic Stem Cell Transplantation

Joost Van Der Hem, Peter Van Balen, Sabrina Veld, Peter A. Von Dem Borne, Danielle Van Lammeren, Tjeerd Snijders, Jaap Jan Zwaginga, Hendrik Veelken, Rosa De Groot, Inge Jedema, Liesbeth C. de Wreede, Constantijn Halkes, J.H. Frederik Falkenburg

Blood (2023) 142 (Supplement 1): 6887.

https://doi.org/10.1182/blood-2023-188843

Published: 2023

Journal Articles

A unique immune signature in blood separates therapy-refractory from therapy-responsive acute graft-versus-host disease

Astrid G. S. van Halteren, Jessica S. Suwandi, Sander Tuit, Jelske Borst, Sandra Laban, Roula Tsonaka, Ada Struijk, Anna-Sophia Wiekmeijer, Melissa van Pel, Bart O. Roep, Jaap Jan Zwaginga, Arjan C. Lankester, Koen Schepers, Maarten J. D. van Tol, Willem E. Fibbe

Blood (2023) 141 (11): 1277–1292.

https://doi.org/10.1182/blood.2022015734

Published: 2023

Includes: Supplemental data

Journal Articles

Effect of Change in Haemoglobin Mass on Physiology in Anaemic and Non-Anaemic Subjects: An Umbrella Review

Rik Tonino, Lisa Zwaginga, Martin R. Schipperus, Jaap Jan Zwaginga

Blood (2022) 140 (Supplement 1): 13138–13140.

https://doi.org/10.1182/blood-2022-163292

Published: 2022

Journal Articles

Platelets from donors with consistently low HLA-B8, -B12, or -B35 expression do not undergo antibody-mediated internalization

Anno Saris, Bert Tomson, Anneke Brand, Arend Mulder, Frans H. Claas, Jos Lorinser, John Scharenberg, S. Marieke van Ham, Anja ten Brinke, Jaap Jan Zwaginga, Pieter F. van der Meer

Blood (2018) 131 (1): 144–152.

https://doi.org/10.1182/blood-2017-07-799270

Published: 2018

Includes: Supplemental data

Journal Articles

The Identification of Cases with Major Hemorrhage in Routinely Recorded Healthcare Data

Aukje Kreuger, Rutger Middelburg, Erik AM Beckers, MD PhD, Karen Vooght, Jaap Jan Zwaginga, MD PhD, Jean-Louis Kerkhoffs, MD PhD, Anske G van der Bom, MD PhD

Blood (2017) 130 (Supplement 1): 2144.

https://doi.org/10.1182/blood.V130.Suppl_1.2144.2144

Published: 2017

Journal Articles

The Role of Platelets in the Induction of Alloimmunization after Platelet Transfusion

Anno Saris, MSc, Pieter F. Van Der Meer, PhD, Sander Meijer, PhD, Ivan Peyron, Marieke van Ham, PhD, Anja ten Brinke, PhD, Jaap Jan Zwaginga, MD PhD

Blood (2017) 130 (Supplement 1): 3726.

https://doi.org/10.1182/blood.V130.Suppl_1.3726.3726

Published: 2017

Journal Articles

Platelets from Donors with Consistent Low HLA-B8, B12 or B35 Expression Do Not Undergo Antibody-Mediated Internalization

Anno Saris, MSc, Bert Tomson, PhD, Anneke Brand, PhD, Arend Mulder, PhD, Frans H.J. Claas, PhD, Jos Lorinser, John Scharenberg, PhD, Marieke van Ham, PhD, Anja ten Brinke, PhD, Jaap Jan Zwaginga, MD PhD, Pieter F. Van Der Meer, PhD

Blood (2017) 130 (Supplement 1): 3727.

https://doi.org/10.1182/blood.V130.Suppl_1.3727.3727

Published: 2017

Journal Articles

Sequestration Pattern in ITP Liver/Spleen Scan Correlates with the Presence of Anti-Glycoprotein V Antibodies in ITP Patients

Sufia N. Amini, MD, Annemieke Sobels, MSc, Christianne Duchateau, MD, Masja De Haas, MD PhD, Leendert Porcelijn, MD, Roger Schutgens, MD PhD, Jaap Jan Zwaginga, MD PhD, Martin R. Schipperus, MD PhD

Blood (2017) 130 (Supplement 1): 1046.

https://doi.org/10.1182/blood.V130.Suppl_1.1046.1046

Published: 2017

Journal Articles

Lack of detectable platelet autoantibodies is correlated with nonresponsiveness to rituximab treatment in ITP patients

Leendert Porcelijn, Elly Huiskes, Martin Schipperus, Bronno van der Holt, Masja de Haas, Jaap Jan Zwaginga

Blood (2017) 129 (25): 3389–3391.

https://doi.org/10.1182/blood-2016-11-751719

Published: 2017

Includes: Supplemental data

Journal Articles

Splenectomy Protects Humans from Red Cell Alloimmunization

Dorothea Evers, MD, Johanna G van der Bom, MD PhD, Janneke Tijmensen, MD, Masja de Haas, MD PhD Prof., Rutger A Middelburg, PhD, Karen de Vooght, PhD, Daan van de Kerkhof, PhD, Otto Visser, MD PhD, Nathalie Pequeriaux, MD, Fransisca Hudig, PhD, Jaap Jan Zwaginga, MD PhD

Blood (2016) 128 (22): 24.

https://doi.org/10.1182/blood.V128.22.24.24

Published: 2016

Journal Articles

Direct Comparison of Wharton Jelly and Bone Marrow Derived Mesenchymal Stromal Cells to Enhance Engraftment of Cord Blood CD34 + Transplants

Mark van der Garde, Melissa Van Pel, PhD, Jose Millan Rivero, Alice de Graaf-Dijkstra, Manon Slot, Yoshiko Kleinveld, Suzanne Watt, PhDFRCPath, Helene Roelofs, PhD, Jaap Jan Zwaginga, MD PhD

Blood (2015) 126 (23): 5410.

https://doi.org/10.1182/blood.V126.23.5410.5410

Published: 2015

Journal Articles

The Immunogenicity of Red Blood Cell Antigens in Relation to Antigen Exposure

Dorothea Evers, MD, Rutger Middelburg, PhD, Masja De Haas, Prof, MD, Saurabh Zalpuri, MD PhD, Karen de Vooght, PhD, Daan van de Kerkhof, PhD, Otto Visser, MD PhD, Nathalie Pequeriaux, Francisca Hudig, PhD, Henk Schonewille, PhD, Jaap Jan Zwaginga, MD PhD, Anske van der Bom, MD PhD

Blood (2015) 126 (23): 1139.

https://doi.org/10.1182/blood.V126.23.1139.1139

Published: 2015

Journal Articles

Detection of Platelet Autoantibodies Revisited to Identify Immune Thrombocytopenia

Leendert Porcelijn, MD, Elly Huiskes, Gonda Oldert, Rob Fijnheer, MD PhD, Martin R. Schipperus, MD PhD, Jaap Jan Zwaginga, MD PhD, Masja De Haas, Prof, MD

Blood (2015) 126 (23): 1142.

https://doi.org/10.1182/blood.V126.23.1142.1142

Published: 2015

Journal Articles

HLA class II upregulation during viral infection leads to HLA-DP–directed graft-versus-host disease after CD4+ donor lymphocyte infusion

Sanja Stevanović, Cornelis A. M. van Bergen, Simone A. P. van Luxemburg-Heijs, Boris van der Zouwen, Ekaterina S. Jordanova, Alwine B. Kruisselbrink, Marian van de Meent, Jessica C. Harskamp, Frans H. J. Claas, Erik W. A. Marijt, Jaap Jan Zwaginga, Constantijn J. M. Halkes, Inge Jedema, Marieke Griffioen, J. H. Frederik Falkenburg

Blood (2013) 122 (11): 1963–1973.

https://doi.org/10.1182/blood-2012-12-470872

Published: 2013

Includes: Supplemental data

Journal Articles

MEIS1 Induces a Megakaryocyte-Erythroid Fate by Upregulation of FOG1 and GATA1 Expression.

Sabrina Zeddies, Sjoert B.G. Jansen, Sylvia Nuernberg, Summa di Franca, Willem H Ouwehand, Jaap Jan Zwaginga, MD, PhD, Mattia Frontini, Marieke von Lindern, PhD, Augosto Rendon, Ellen C.E. van der Schoot, MD, PhD, Daphne C Thijssen-Timmer, PhD

Blood (2012) 120 (21): 2330.

https://doi.org/10.1182/blood.V120.21.2330.2330

Published: 2012

Journal Articles

MEIS1 Regulates Early Erythroid and Megakaryocytic Lineage Decision

Sabrina Zeddies, Sjoert Jansen, Franca di Summa, Sofieke Klamer, Marion Kleier, Jaap Jan Zwaginga, MD, PhD, Marieke von Lindern, PhD, C. Ellen Van der Schoot, Daphne C Thijssen-Timmer, PhD

Blood (2011) 118 (21): 2365.

https://doi.org/10.1182/blood.V118.21.2365.2365

Published: 2011

Journal Articles

Transcription profiling in human platelets reveals LRRFIP1 as a novel protein regulating platelet function

Blood (2010) 116 (22): 4646–4656.

https://doi.org/10.1182/blood-2010-04-280925

Published: 2010

Includes: Supplemental data

Journal Articles

Early Intervention with Mesenchymal Stromal Cells for Refractory Grade III-IV Graft Versus Host Disease In Children Results In Excellent Long Term Outcome

Lynne Margaret Ball, MD, PhD, Maria E. Bernardo, MD, PhD, Jaap Jan Zwaginga, MD, PhD, Maarten van Tol, PhD, Angela Cometa, Helene Roelofs, PhD, Giovanna Giorgiani, Cornelia M Jol-van der Zijde, PhD, Maria Antonietta Avanzini, MD, Katarina Le Blanc, MD, PhD, Alice Bertaina, Francesco Frassoni, MD, Willem E. Fibbe, MD, PhD, Olle Ringden, MD, R. Maarten Egeler, MD, PhD, Franco Locatelli, MD, Arjan Lankester, MD, PhD

Blood (2010) 116 (21): 2336.

https://doi.org/10.1182/blood.V116.21.2336.2336

Published: 2010

Journal Articles

Interim Analysis on a Dutch HOVON Multicenter Randomized Open Label Phase II Trial on 3 Rituximab Dosing Schemes In Chronic ITP Patients:

Jaap Jan Zwaginga, MD, PhD, Ronnie van der Holt, PhD, Bart J. Biemond, MD, PhD, Peter A.W. te Boekhorst, MD, PhD, Mark Levin, MD, PhD, Art Vreughdenhil, MD, PhD, P.C. Huijgens, MD, PhD, Anneke Brand, MD, PhD, Rene van der Griend, MD, PhD, Marleen Luten, Hans Pruijt, MD, PhD, Okke de Weerdt, Elisabeth van Pampus, MD, PhD, Sonja Zweegman, MD, PhD, Rene Hollestein, Harry R. Koene, MD, PhD

Blood (2010) 116 (21): 2514.

https://doi.org/10.1182/blood.V116.21.2514.2514

Published: 2010

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The ‘Stop TPO-Receptor Agonist in ITP Patients’ (STIP) Study: Clinical and Immune Modulatory Effects of Romiplostim Tapering

Randomized Trial of Prophylactic Donor Lymphocyte Infusion with Positively Selected CD4+ T Cells after HLA-Identical Allogeneic Stem Cell Transplantation

A unique immune signature in blood separates therapy-refractory from therapy-responsive acute graft-versus-host disease

Effect of Change in Haemoglobin Mass on Physiology in Anaemic and Non-Anaemic Subjects: An Umbrella Review

Platelets from donors with consistently low HLA-B8, -B12, or -B35 expression do not undergo antibody-mediated internalization

The Identification of Cases with Major Hemorrhage in Routinely Recorded Healthcare Data

The Role of Platelets in the Induction of Alloimmunization after Platelet Transfusion

Platelets from Donors with Consistent Low HLA-B8, B12 or B35 Expression Do Not Undergo Antibody-Mediated Internalization

Sequestration Pattern in ITP Liver/Spleen Scan Correlates with the Presence of Anti-Glycoprotein V Antibodies in ITP Patients

Lack of detectable platelet autoantibodies is correlated with nonresponsiveness to rituximab treatment in ITP patients

Splenectomy Protects Humans from Red Cell Alloimmunization

Direct Comparison of Wharton Jelly and Bone Marrow Derived Mesenchymal Stromal Cells to Enhance Engraftment of Cord Blood CD34 + Transplants

The Immunogenicity of Red Blood Cell Antigens in Relation to Antigen Exposure

Detection of Platelet Autoantibodies Revisited to Identify Immune Thrombocytopenia

HLA class II upregulation during viral infection leads to HLA-DP–directed graft-versus-host disease after CD4+ donor lymphocyte infusion

MEIS1 Induces a Megakaryocyte-Erythroid Fate by Upregulation of FOG1 and GATA1 Expression.

MEIS1 Regulates Early Erythroid and Megakaryocytic Lineage Decision

Transcription profiling in human platelets reveals LRRFIP1 as a novel protein regulating platelet function

Early Intervention with Mesenchymal Stromal Cells for Refractory Grade III-IV Graft Versus Host Disease In Children Results In Excellent Long Term Outcome

Interim Analysis on a Dutch HOVON Multicenter Randomized Open Label Phase II Trial on 3 Rituximab Dosing Schemes In Chronic ITP Patients:

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