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Ivan Krivega
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Journal Articles

Targeted Non-Viral Gene Delivery through Transcutaneous Ultrasound Enables Robust, Redosable, Titratable, and Durable FVIII and FIX Gene Expression in the Liver in Murine Models

Surabhi Rao, Victor Foster, Charles Levine, Bert Frederich, Jonathan Chan, Barry Campbell, Glenda Arauz, Celia Ortiz, Adel Alonso, Oliver Chen, Tanaya Ghosh, Charlotte He, Elizabeth Del Greco, David Satyadi, Anagha Rao, David Kim, Dhruv Bole, Katelyn N Benthall, Margarita Krivega, Julia Poniatowski, Ivan Krivega, Zoya Gulzman-Poltorak, Steve Feinstein, Kenneth Greenberg
Journal: Blood
Blood (2024) 144 (Supplement 1): 2232.
https://doi.org/10.1182/blood-2024-208969
Published: 2024
Journal Articles

Engineering FVIII Protein for Enhancing Expression and Secretion Profile to Achieve Normal Level of FVIII in Plasma Utilizing Noninvasive Transcutaneous Ultrasound Mediated Gene Delivery

Ivan Krivega, Margarita Krivega, Julia Poniatowski, David Kim, Elizabeth Del Greco, Surabhi Rao, Victor Foster, Bert Frederich, Glenda Arauz, Celia Ortiz, Oliver Chen, Tanaya Ghosh, Dhruv Bole, Katelyn N Benthall, Anagha Rao, David Satyadi, Zoya Gulzman-Poltorak, Steve Feinstein, Kenneth Greenberg
Journal: Blood
Blood (2024) 144 (Supplement 1): 7458.
https://doi.org/10.1182/blood-2024-209151
Published: 2024
Journal Articles

Engineering Non-Viral Gene Therapy Vector for Simultaneous Transgenic FVIII Protein Expression from Liver Sinusoidal Endothelial Cells (LSECs) and Hepatocytes upon Non-Invasive Transcutaneous Ultrasound-Mediated Gene Delivery

Ivan Krivega, Margarita Krivega, Julia Poniatowski, David Kim, Elizabeth Del Greco, Surabhi Rao, Victor Foster, Bert Frederich, Glenda Arauz, Celia Ortiz, Tanaya Ghosh, Oliver Chen, Dhruv Bole, Katelyn N Benthall, David Satyadi, Steve Feinstein, Kenneth Greenberg
Journal: Blood
Blood (2024) 144 (Supplement 1): 7459.
https://doi.org/10.1182/blood-2024-209270
Published: 2024
Journal Articles

Fetal γ-globin genes are regulated by the BGLT3 long noncoding RNA locus

Maria Soledad Ivaldi, Luis Francisco Diaz, Lyubomira Chakalova, Jongjoo Lee, Ivan Krivega, Ann Dean
Journal: Blood
Blood (2018) 132 (18): 1963–1973.
https://doi.org/10.1182/blood-2018-07-862003
Published: 2018
Includes: Supplemental data
Journal Articles

New Concepts in Genome Regulation

Ann Dean, PhD, Jongjoo Lee, Ryan Dale, Ivan Krivega, PhD
Journal: Blood
Blood (2016) 128 (22): SCI-47.
https://doi.org/10.1182/blood.V128.22.SCI-47.SCI-47
Published: 2016
Journal Articles

Inhibition of G9a methyltransferase stimulates fetal hemoglobin production by facilitating LCR/γ-globin looping

Ivan Krivega, Colleen Byrnes, Jaira F. de Vasconcellos, Y. Terry Lee, Megha Kaushal, Ann Dean, Jeffery L. Miller
Journal: Blood
Blood (2015) 126 (5): 665–672.
https://doi.org/10.1182/blood-2015-02-629972
Published: 2015
Includes: Supplemental data
Journal Articles

Inhibition of G9a Methyltransferase in Adult Human Erythroblasts Stimulates Fetal Hemoglobin Production By Facilitating Looping Between LCR and γ-Globin Gene

Ivan Krivega, Colleen Byrnes, Jaira F. de Vasconcellos, Y. Terry Lee, Megha Kaushal, Ann Dean, Jeffery L. Miller
Journal: Blood
Blood (2014) 124 (21): 332.
https://doi.org/10.1182/blood.V124.21.332.332
Published: 2014