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Journal Articles

Dynamin 2 (DNM2) and PACSIN2 Regulate Megakaryocyte Demarcation Membrane System Formation and Platelet Production in Concert

Silvia Giannini, PhD, Markus Bender, PhD, Fred G. Pluthero, PhD, Hilary Christensen, PhD, Richard Leung, PhD, Richard W. Lo, PhD, Jan Kormann, PhD, Markus Plomann, PhD, Walter H.A. Kahr, MD PhD, Hervé Falet, PhD

Blood (2015) 126 (23): 419.

https://doi.org/10.1182/blood.V126.23.419.419

Published: 2015

Journal Articles

FlnA binding to PACSIN2 F-BAR domain regulates membrane tubulation in megakaryocytes and platelets

Antonija Jurak Begonja, Fred G. Pluthero, Worawit Suphamungmee, Silvia Giannini, Hilary Christensen, Richard Leung, Richard W. Lo, Fumihiko Nakamura, William Lehman, Markus Plomann, Karin M. Hoffmeister, Walter H. A. Kahr, John H. Hartwig, Hervé Falet

Blood (2015) 126 (1): 80–88.

https://doi.org/10.1182/blood-2014-07-587600

Published: 2015

Includes: Multimedia, Supplemental data

Journal Articles

Dynamin 2–dependent endocytosis is required for normal megakaryocyte development in mice

Markus Bender, Silvia Giannini, Renata Grozovsky, Terese Jönsson, Hilary Christensen, Fred G. Pluthero, Amy Ko, Ann Mullally, Walter H. A. Kahr, Karin M. Hoffmeister, Hervé Falet

Blood (2015) 125 (6): 1014–1024.

https://doi.org/10.1182/blood-2014-07-587857

Published: 2015

Journal Articles

Dynamin 2-Dependent Endocytosis Regulates Megakaryopoiesis

Markus Bender, Silvia Giannini, Terese Jönsson, Renata Grozovsky, PhD, Hilary Christensen, Fred G Pluthero, Walter H Kahr, Karin M Hoffmeister, MD, Hervé Falet, PhD

Blood (2014) 124 (21): 339.

https://doi.org/10.1182/blood.V124.21.339.339

Published: 2014

Journal Articles

Specific Gtpase Dynamin Isoforms Regulate Megakaryocyte Membrane Remodeling and The Formation Of Multivesicular Bodies and Microparticles

Yolande Chen, MD, Arinola Awomolo, MD, Jorie Aardema, BS, Michael Hession, Francisco Javier Gonzalez, MD, Hilary Christensen, Walter H. Kahr, MD, PhD, Seth J. Corey, MD, MPH

Blood (2013) 122 (21): 3529.

https://doi.org/10.1182/blood.V122.21.3529.3529

Published: 2013

Journal Articles

Platelet Functional and Morphological Abnormalities In a Case Of Arthrogryposis, Renal Dysfunction and Cholestasis (ARC) Syndrome With a Novel Genetic Profile

Lesleigh S Abbott, MD, Ling Li, MD, Hilary Christensen, Fred Pluthero, PhD, Denisa Urban, Yigal Dror, MD, Walter H. Kahr, MD, PhD

Blood (2013) 122 (21): 3538.

https://doi.org/10.1182/blood.V122.21.3538.3538

Published: 2013

Journal Articles

Abnormal megakaryocyte development and platelet function in Nbeal2 −/− mice

Walter H. A. Kahr, Richard W. Lo, Ling Li, Fred G. Pluthero, Hilary Christensen, Ran Ni, Nima Vaezzadeh, Cynthia E. Hawkins, Andrew S. Weyrich, Jorge Di Paola, Carolina Landolt-Marticorena, Peter L. Gross

Blood (2013) 122 (19): 3349–3358.

https://doi.org/10.1182/blood-2013-04-499491

Published: 2013

Includes: Supplemental data

Journal Articles

Loss of the F-BAR protein CIP4 reduces platelet production by impairing membrane-cytoskeleton remodeling

Blood (2013) 122 (10): 1695–1706.

https://doi.org/10.1182/blood-2013-03-484550

Published: 2013

Journal Articles

The VPS33B-binding protein VPS16B is required in megakaryocyte and platelet α-granule biogenesis

Denisa Urban, Ling Li, Hilary Christensen, Fred G. Pluthero, Shao Zun Chen, Michael Puhacz, Parvesh M. Garg, Kiran K. Lanka, James J. Cummings, Helmut Kramer, James D. Wasmuth, John Parkinson, Walter H. A. Kahr

Blood (2012) 120 (25): 5032–5040.

https://doi.org/10.1182/blood-2012-05-431205

Published: 2012

Includes: Supplemental data

Journal Articles

Comparative Cellular Studies of the VWF Exon 4–5 Deletion Mutation Using Patient-Derived Blood Outgrowth Endothelial Cells (BOEC) and Megakaryocytes

Mackenzie L Bowman, MSc, Ling Li, MD, Fred Pluthero, PhD, Hilary Christensen, Irwin Walker, MBBS, Walter H. Kahr, MD, PhD, Paula D. James, MD

Blood (2012) 120 (21): 1076.

https://doi.org/10.1182/blood.V120.21.1076.1076

Published: 2012

Journal Articles

Thrombocytopenia and Platelet Ultra-Structural Abnormalities Associated with RUNX1 Haploinsufficiency in Monosomy 21 Mosaicism.

Riten Kumar, MD, MSc, Fred Pluthero, PhD, Hilary Christensen, Walter H. Kahr, MD, PhD

Blood (2012) 120 (21): 2190.

https://doi.org/10.1182/blood.V120.21.2190.2190

Published: 2012

Journal Articles

Identification of a VPS33B-Binding Protein That Facilitates Alpha Granule Formation In Human Megakaryocytes and Platelets.

Denisa Urban, Ling Li, MD, James Wasmuth, PhD, Hilary Christensen, John Parkinson, PhD, Walter H. Kahr, MD, PhD

Blood (2010) 116 (21): 1444.

https://doi.org/10.1182/blood.V116.21.1444.1444

Published: 2010

Journal Articles

Platelet-associated complement factor H in healthy persons and patients with atypical HUS

Christoph Licht, Fred G. Pluthero, Ling Li, Hilary Christensen, Sandra Habbig, Bernd Hoppe, Denis F. Geary, Peter F. Zipfel, Walter H. A. Kahr

Blood (2009) 114 (20): 4538–4545.

https://doi.org/10.1182/blood-2009-03-205096

Published: 2009

Journal Articles

Incomplete Platelet Dense Granule Formation in Normal Neonates.

Walter H. Kahr, MD, PhD, Shoma Baidya, MD, Animitra Das, MD, Ayca Toprak, Hilary Christensen, Fanny Meulman, Margaret L. Rand, PhD, Fred G. Pluthero, PhD, David Chitayat, MD, Prakeshkumar Shah, MD, Victor S. Blanchette, MB, ChB

Blood (2007) 110 (11): 3210.

https://doi.org/10.1182/blood.V110.11.3210.3210

Published: 2007

Journal Articles

Requirement of VPS33B, a member of the Sec1/Munc18 protein family, in megakaryocyte and platelet α-granule biogenesis

Bryan Lo, Ling Li, Paul Gissen, Hilary Christensen, Patrick J. McKiernan, Charles Ye, Mohamed Abdelhaleem, Jason A. Hayes, Michael D. Williams, David Chitayat, Walter H. A. Kahr

Blood (2005) 106 (13): 4159–4166.

https://doi.org/10.1182/blood-2005-04-1356

Published: 2005

Journal Articles

Congenital Macrothrombocytopenia and Defective Localization of the Nonmuscle Myosin Heavy Chain IIA in Leukocytes and Megakaryocytes with a Normal MYH9 Gene.

Walter H. Kahr, MD, PhD, FRCPC, Ling Li, MD, MSc, Chanchai Traivaree, MD, Hilary Christensen, BA, MLTU, Tara Paton, PhD, Sheila E. Butchard, RN, Julie Curtin, MBBS, PhD, Victor S. Blanchette, FRCP

Blood (2004) 104 (11): 3032.

https://doi.org/10.1182/blood.V104.11.3032.3032

Published: 2004

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Dynamin 2 (DNM2) and PACSIN2 Regulate Megakaryocyte Demarcation Membrane System Formation and Platelet Production in Concert

FlnA binding to PACSIN2 F-BAR domain regulates membrane tubulation in megakaryocytes and platelets

Dynamin 2–dependent endocytosis is required for normal megakaryocyte development in mice

Dynamin 2-Dependent Endocytosis Regulates Megakaryopoiesis

Specific Gtpase Dynamin Isoforms Regulate Megakaryocyte Membrane Remodeling and The Formation Of Multivesicular Bodies and Microparticles

Platelet Functional and Morphological Abnormalities In a Case Of Arthrogryposis, Renal Dysfunction and Cholestasis (ARC) Syndrome With a Novel Genetic Profile

Abnormal megakaryocyte development and platelet function in Nbeal2 −/− mice

Loss of the F-BAR protein CIP4 reduces platelet production by impairing membrane-cytoskeleton remodeling

The VPS33B-binding protein VPS16B is required in megakaryocyte and platelet α-granule biogenesis

Comparative Cellular Studies of the VWF Exon 4–5 Deletion Mutation Using Patient-Derived Blood Outgrowth Endothelial Cells (BOEC) and Megakaryocytes

Thrombocytopenia and Platelet Ultra-Structural Abnormalities Associated with RUNX1 Haploinsufficiency in Monosomy 21 Mosaicism.

Identification of a VPS33B-Binding Protein That Facilitates Alpha Granule Formation In Human Megakaryocytes and Platelets.

Platelet-associated complement factor H in healthy persons and patients with atypical HUS

Incomplete Platelet Dense Granule Formation in Normal Neonates.

Requirement of VPS33B, a member of the Sec1/Munc18 protein family, in megakaryocyte and platelet α-granule biogenesis

Congenital Macrothrombocytopenia and Defective Localization of the Nonmuscle Myosin Heavy Chain IIA in Leukocytes and Megakaryocytes with a Normal MYH9 Gene.

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