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Journal Articles

A comprehensive transcriptome signature of murine hematopoietic stem cell aging

Arthur Flohr Svendsen, Daozheng Yang, KyungMok Kim, Seka Lazare, Natalia Skinder, Erik Zwart, Anna Mura-Meszaros, Albertina Ausema, Björn von Eyss, Gerald de Haan, Leonid Bystrykh

Blood (2021) 138 (6): 439–451.

https://doi.org/10.1182/blood.2020009729

Published: 2021

Includes: Supplemental data

Journal Articles

Aging of hematopoietic stem cells

Gerald de Haan, Seka Simone Lazare

Blood (2018) 131 (5): 479–487.

https://doi.org/10.1182/blood-2017-06-746412

Published: 2018

Journal Articles

Genomic and functional integrity of the hematopoietic system requires tolerance of oxidative DNA lesions

Ana Martín-Pardillos, Anastasia Tsaalbi-Shtylik, Si Chen, Seka Lazare, Ronald P. van Os, Albertina Dethmers-Ausema, Nima Borhan Fakouri, Matthias Bosshard, Rossana Aprigliano, Barbara van Loon, Daniela C. F. Salvatori, Keiji Hashimoto, Celia Dingemanse-van der Spek, Masaaki Moriya, Lene Juel Rasmussen, Gerald de Haan, Marc H. G. P. Raaijmakers, Niels de Wind

Blood (2017) 130 (13): 1523–1534.

https://doi.org/10.1182/blood-2017-01-764274

Published: 2017

Includes: Supplemental data

Journal Articles

Clonal selection and asymmetric distribution of human leukemia in murine xenografts revealed by cellular barcoding

Mirjam E. Belderbos, Taco Koster, Bertien Ausema, Sabrina Jacobs, Sharlaine Sowdagar, Erik Zwart, Eveline de Bont, Gerald de Haan, Leonid V. Bystrykh

Blood (2017) 129 (24): 3210–3220.

https://doi.org/10.1182/blood-2016-12-758250

Published: 2017

Includes: Supplemental data

Journal Articles

The Role of Cbx Proteins in Human Benign and Malignant Hematopoiesis

Johannes Jung, MD, Hein Schepers, PhD, Seka Lazare, Sonja Buisman, Ellen Weersing, Bertien Dethmers, Karin Klauke, PhD, Lenja Bystrykh, PhD, Gerald De Haan, PhD

Blood (2016) 128 (22): 2651.

https://doi.org/10.1182/blood.V128.22.2651.2651

Published: 2016

Journal Articles

Heterogeneity of young and aged murine hematopoietic stem cells revealed by quantitative clonal analysis using cellular barcoding

Evgenia Verovskaya, Mathilde J. C. Broekhuis, Erik Zwart, Martha Ritsema, Ronald van Os, Gerald de Haan, Leonid V. Bystrykh

Blood (2013) 122 (4): 523–532.

https://doi.org/10.1182/blood-2013-01-481135

Published: 2013

Includes: Supplemental data

Journal Articles

The combination of valproic acid and lithium delays hematopoietic stem/progenitor cell differentiation

Marta A. Walasek, Leonid Bystrykh, Vincent van den Boom, Sandra Olthof, Albertina Ausema, Martha Ritsema, Gerwin Huls, Gerald de Haan, Ronald van Os

Blood (2012) 119 (13): 3050–3059.

https://doi.org/10.1182/blood-2011-08-375386

Published: 2012

Includes: Supplemental data

Journal Articles

Genetic screen identifies microRNA cluster 99b/let-7e/125a as a regulator of primitive hematopoietic cells

Alice Gerrits, Marta A. Walasek, Sandra Olthof, Ellen Weersing, Martha Ritsema, Erik Zwart, Ronald van Os, Leonid V. Bystrykh, Gerald de Haan

Blood (2012) 119 (2): 377–387.

https://doi.org/10.1182/blood-2011-01-331686

Published: 2012

Includes: Supplemental data

Journal Articles

Tracking Reconstitution Dynamics in Mice Co-Transplanted with Hematopoietic Stem Cells From Nine Distinguishable Donor Types

Brad Dykstra, PhD, Sulima Geerman, Jaring Schreuder, Martha Ritsema, Gerald De Haan, PhD

Blood (2011) 118 (21): 1890.

https://doi.org/10.1182/blood.V118.21.1890.1890

Published: 2011

Journal Articles

CITED2 Modulates Differentiation and Proliferation of Normal and Leukemic Hematopoietic Stem and Progenitor Cells Downstream of PU.1

Hein Schepers, Ph.D, Patrick M. Korthuis, Jan J. Schuringa, PhD, Gerald de Haan, Ph.D, Edo Vellenga, PhD

Blood (2011) 118 (21): 922.

https://doi.org/10.1182/blood.V118.21.922.922

Published: 2011

Journal Articles

BMI1 collaborates with BCR-ABL in leukemic transformation of human CD34 + cells

Aleksandra Rizo, Sarah J. Horton, Sandra Olthof, Bert Dontje, Albertina Ausema, Ronald van Os, Vincent van den Boom, Edo Vellenga, Gerald de Haan, Jan Jacob Schuringa

Blood (2010) 116 (22): 4621–4630.

https://doi.org/10.1182/blood-2010-02-270660

Published: 2010

Includes: Supplemental data

Journal Articles

Effects of Age and Environment on Short-Term Homing and Function of Mouse Hematopoietic Stem Cells.

Brad Dykstra, PhD, Sandra Olthof, Martha Ritsema, Gerald De Haan, PhD

Blood (2010) 116 (21): 1616.

https://doi.org/10.1182/blood.V116.21.1616.1616

Published: 2010

Journal Articles

Cellular barcoding tool for clonal analysis in the hematopoietic system

Alice Gerrits, Brad Dykstra, Olga J. Kalmykowa, Karin Klauke, Evgenia Verovskaya, Mathilde J. C. Broekhuis, Gerald de Haan, Leonid V. Bystrykh

Blood (2010) 115 (13): 2610–2618.

https://doi.org/10.1182/blood-2009-06-229757

Published: 2010

Journal Articles

Repression of BMI1 in normal and leukemic human CD34 + cells impairs self-renewal and induces apoptosis

Aleksandra Rizo, Sandra Olthof, Lina Han, Edo Vellenga, Gerald de Haan, Jan Jacob Schuringa

Blood (2009) 114 (8): 1498–1505.

https://doi.org/10.1182/blood-2009-03-209734

Published: 2009

Journal Articles

Long-term maintenance of human hematopoietic stem/progenitor cells by expression of BMI1

Aleksandra Rizo, Bert Dontje, Edo Vellenga, Gerald de Haan, Jan Jacob Schuringa

Blood (2008) 111 (5): 2621–2630.

https://doi.org/10.1182/blood-2007-08-106666

Published: 2008

Includes: Supplemental data

Journal Articles

Unexpected Consequences of Sitosterolemia on Platelet Formation.

Lyndsay Drayer, PhD, Janine Kruit, PhD, Bert Dontje, Gerald de Haan, PhD, Ido Kema, PhD, Edo Vellenga, MD, PhD, Folkert Kuipers, PhD

Blood (2006) 108 (11): 1090.

https://doi.org/10.1182/blood.V108.11.1090.1090

Published: 2006

Journal Articles

Ex-Vivo Expansion of Human Cord Blood CD34+ Cells by Overexpression of Bmi-1.

Aleksandra Rizo, MD, Edo Vellenga, MD,PhD, Gerald de Haan, PhD, Jan Jacob Schuringa, PhD

Blood (2006) 108 (11): 1329.

https://doi.org/10.1182/blood.V108.11.1329.1329

Published: 2006

Journal Articles

The Polycomb group gene Ezh2 prevents hematopoietic stem cell exhaustion

Leonie M. Kamminga, Leonid V. Bystrykh, Aletta de Boer, Sita Houwer, José Douma, Ellen Weersing, Bert Dontje, Gerald de Haan

Blood (2006) 107 (5): 2170–2179.

https://doi.org/10.1182/blood-2005-09-3585

Published: 2006

Includes: Supplemental data

Journal Articles

Differential Role for VLA-5 in Mobilization of Heamotopoieic Stem Cells Toward Peripheral Blood and Homing to Bone Marrow and Spleen.

Pieter K. Wierenga, PhD, Ellen Weersing, Bert Dontje, Gerald de Haan, PhD, Ronald P. van Os, PhD

Blood (2005) 106 (11): 2190.

https://doi.org/10.1182/blood.V106.11.2190.2190

Published: 2005

Journal Articles

Competitive clonal hematopoiesis in mouse chimeras explained by a stochastic model of stem cell organization

Ingo Roeder, Leonie M. Kamminga, Katrin Braesel, Bert Dontje, Gerald de Haan, Markus Loeffler

Blood (2005) 105 (2): 609–616.

https://doi.org/10.1182/blood-2004-01-0282

Published: 2005

Includes: Supplemental data

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A comprehensive transcriptome signature of murine hematopoietic stem cell aging

Aging of hematopoietic stem cells

Genomic and functional integrity of the hematopoietic system requires tolerance of oxidative DNA lesions

Clonal selection and asymmetric distribution of human leukemia in murine xenografts revealed by cellular barcoding

The Role of Cbx Proteins in Human Benign and Malignant Hematopoiesis

Heterogeneity of young and aged murine hematopoietic stem cells revealed by quantitative clonal analysis using cellular barcoding

The combination of valproic acid and lithium delays hematopoietic stem/progenitor cell differentiation

Genetic screen identifies microRNA cluster 99b/let-7e/125a as a regulator of primitive hematopoietic cells

Tracking Reconstitution Dynamics in Mice Co-Transplanted with Hematopoietic Stem Cells From Nine Distinguishable Donor Types

CITED2 Modulates Differentiation and Proliferation of Normal and Leukemic Hematopoietic Stem and Progenitor Cells Downstream of PU.1

BMI1 collaborates with BCR-ABL in leukemic transformation of human CD34 + cells

Effects of Age and Environment on Short-Term Homing and Function of Mouse Hematopoietic Stem Cells.

Cellular barcoding tool for clonal analysis in the hematopoietic system

Repression of BMI1 in normal and leukemic human CD34 + cells impairs self-renewal and induces apoptosis

Long-term maintenance of human hematopoietic stem/progenitor cells by expression of BMI1

Unexpected Consequences of Sitosterolemia on Platelet Formation.

Ex-Vivo Expansion of Human Cord Blood CD34+ Cells by Overexpression of Bmi-1.

The Polycomb group gene Ezh2 prevents hematopoietic stem cell exhaustion

Differential Role for VLA-5 in Mobilization of Heamotopoieic Stem Cells Toward Peripheral Blood and Homing to Bone Marrow and Spleen.

Competitive clonal hematopoiesis in mouse chimeras explained by a stochastic model of stem cell organization

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