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Florian Zettl
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Journal Articles

Safety of Front-Line R-Mini-CHOP with or without Acalabrutinib in Older Adults with DLBCL - an Interim Analysis of Serious Adverse Events in the Arched / GLA 2022-1 Randomized, Open-Label, Phase 3 Trial

Free
Konstantinos Christofyllakis, Igor Age Kos, Bettina Altmann, Viola Poeschel, Stephanie Maurer, Vadim Lesan, Jörg-Thomas Bittenbring, Dominic Kaddu-Mulindwa, Zanir Abdi, Manfred Ahlgrimm, Sarah Altmeyer, Octavian Fleser, Gerhard Held, Maike Nickelsen, Martin Dreyling, Florian Zettl, Christian Buske, Georg Lenz, Bertram Glass, Björn Chapuy, Norbert Schmitz, German Ott, Reiner Siebert, Andreas Viardot, Florian Scherer, Roland Schmitz, Andreas Rosenwald, Dirk Hellwig, Nina Neuendorff, Theodoros Vassilakopoulos, Chrysoula Doxani, Pascal Blatt, Oguzhan Nakisli, Susanne Schmidt, Tobias Gaska, Börge Arndt, Matthias Mueller, Hanno Maximilian Witte, Martin Bentz, Volkmar Boehme, Heinz Kirchen, Markus Loeffler, Boris Kubuschock, Niklas Gebauer, Rolf Mahlberg, Julian Topaly, Alexander Bott, Kai Wille, Ralf Ulrich Trappe, Mathias J. Rummel, Gerald Illerhaus, Franziska Brunner, Martin Klump, Ulrich Kaiser, Swen Wessendorf, Iordanis Deligiannis, Bert Hildebrandt, Alexander Kiani, Thomas Illmer, Gabriele Prange-Krex, Kristina Lerch, Matthias Sandmann, Sebastian Broeckling, Uwe Martens, Bastian von Tresckow, Annkristin Heine, Holger F. Hebart, Stephan Stilgenbauer, Lorenz Thurner, Moritz Bewarder, Marita Ziepert
Journal: Blood
Blood (2024) 144 (Supplement 1): 4498.
https://doi.org/10.1182/blood-2024-199685
Published: 2024
Journal Articles

A Randomized, Open-Label, Phase 3 Study of Acalabrutinib in Combination with Rituximab and Reduced Dose CHOP (R-miniCHOP) in Older Adults with Untreated Diffuse Large B-Cell Lymphoma (ARCHED / GLA 2022-1)

Free
Konstantinos Christofyllakis, Viola Poeschel, Bettina Altmann, Stephanie Maurer, Vadim Lesan, Jörg Bittenbring, Igor Age Kos, Dominic Kaddu-Mulindwa, Zanir Abdi, Octavian Fleser, Sarah Altmeyer, Nina Rosa Neuendorff, Maike Nickelsen, Gerhard Held, Martin Dreyling, Florian Zettl, Christian Buske, Georg Lenz, Bertram Glass, Bjoern Chapuy, Norbert Schmitz, Theodoros Vassilakopoulos, German Ott, Reiner Siebert, Andreas Viardot, Florian Scherer, Roland Schmitz, Andreas Rosenwald, Dirk Hellwig, Markus Loeffler, Stephan Stilgenbauer, Lorenz Thurner, Moritz Bewarder, Marita Ziepert
Journal: Blood
Blood (2023) 142 (Supplement 1): 6248.
https://doi.org/10.1182/blood-2023-179200
Published: 2023
Journal Articles

Rituximab and Bendamustine for First-Line Treatment of Frail or Elderly Patients with Aggressive B-Cell Lymphoma: Final Results of the Prospective Phase-II Brenda Trial of GLA (German Lymphoma Alliance)

Free
Florian Zettl, Friederike Braulke, Marita Ziepert, PhD, Andreas Viardot, MD PhD, Christoph Kahl, MD, Gabriele Prange-Krex, Agnieszka Korfel, Martin H. Dreyling, MD PhD, Thomas Illmer, MD, Josef Birkmann, MD, Ulrich Wedding, Dietmar Reichert, Maike de Wit, MD, Frank Hartmann, MD, Hans-Juergen Hurtz, Norbert Schmitz, MD, Mathias Witzens-Harig, MD, Wolfram Klapper, Andreas Rosenwald, MD, Viola Poeschel, MD, Markus Loeffler, MD, Gerald Wulf, MD, Bettina Altmann, PhD, Lorenz Truemper, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4073.
https://doi.org/10.1182/blood-2019-122948
Published: 2019
Journal Articles

Phase 2 study of the bispecific T-cell engager (BiTE) antibody blinatumomab in relapsed/refractory diffuse large B-cell lymphoma

Free
Clinical Trials & Observations
Andreas Viardot, Marie-Elisabeth Goebeler, Georg Hess, Svenja Neumann, Michael Pfreundschuh, Nicole Adrian, Florian Zettl, Martin Libicher, Cyrus Sayehli, Julia Stieglmaier, Alicia Zhang, Dirk Nagorsen, Ralf C. Bargou
Journal: Blood
Blood (2016) 127 (11): 1410–1416.
https://doi.org/10.1182/blood-2015-06-651380
Published: 2016
Includes: Supplemental data
Journal Articles

Impact of comorbidities on overall survival in patients with chronic myeloid leukemia: results of the randomized CML Study IV

Free
Clinical Trials & Observations
Susanne Saußele, Marie-Paloma Krauß, Rüdiger Hehlmann, Michael Lauseker, Ulrike Proetel, Lida Kalmanti, Benjamin Hanfstein, Alice Fabarius, Doris Kraemer, Wolfgang E. Berdel, Martin Bentz, Peter Staib, Maike de Wit, Martin Wernli, Florian Zettl, Holger F. Hebart, Markus Hahn, Jochen Heymanns, Ingo Schmidt-Wolf, Norbert Schmitz, Michael J. Eckart, Winfried Gassmann, Andrea Bartholomäus, Antonio Pezzutto, Elisabeth Oppliger Leibundgut, Dominik Heim, Stefan W. Krause, Andreas Burchert, Wolf-Karsten Hofmann, Joerg Hasford, Andreas Hochhaus, Markus Pfirrmann, Martin C. Müller
Journal: Blood
Blood (2015) 126 (1): 42–49.
https://doi.org/10.1182/blood-2015-01-617993
Published: 2015
Includes: Supplemental data
Journal Articles

Treatment of Relapsed/Refractory Diffuse Large B-Cell Lymphoma with the Bispecific T-Cell Engager (BiTE ® ) Antibody Construct Blinatumomab: Primary Analysis Results from an Open-Label, Phase 2 Study

Free
Andreas Viardot, Mariele Goebeler, Georg Hess, Svenja Neumann, Michael Pfreundschuh, Nicole Adrian, Florian Zettl, Martin Libicher, Evelyn Degenhard, Julia Stieglmaier, Alicia Zhang, Dirk Nagorsen, Ralf C. Bargou
Journal: Blood
Blood (2014) 124 (21): 4460.
https://doi.org/10.1182/blood.V124.21.4460.4460
Published: 2014
Journal Articles

Clinical Activity of Abemaciclib (LY2835219), a Cell Cycle Inhibitor Selective for CDK4 and CDK6, in Patients with Relapsed or Refractory Mantle Cell Lymphoma

Free
Franck Morschhauser, MD PhD, Kamal Bouabdallah, MD, Stephan Stilgenbauer, MD, Catherine Thieblemont, MD PhD, Martin Wolf, MD, Sophie de Guibert, MD, Florian Zettl, MD, Marjo Hahka-Kemppinen, MD PhD, David Xiaohui Wang, MD PhD, Patrick Brueck, MD, Charles Caldwell, MD, Richard Beckmann, PhD, Lawrence Gelbert, PhD, Damien Cronier, PhD, Ji Lin, PhD, Lily Li, MD, Edward M. Chan, MD, Michael Pfreundschuh, Martin Wilhem, MD, Georg Hess, MD
Journal: Blood
Blood (2014) 124 (21): 3067.
https://doi.org/10.1182/blood.V124.21.3067.3067
Published: 2014
Journal Articles

Paraproteins of familial MGUS/multiple myeloma target family-typical antigens: hyperphosphorylation of autoantigens is a consistent finding in familial and sporadic MGUS/MM

Free
Brief Report
Sandra Grass, Klaus-Dieter Preuss, Stephan Thome, Dennis D. Weisenburger, Vinetta Witt, Jane Lynch, Florian Zettl, Lorenz Trümper, Natalie Fadle, Evi Regitz, Henry Lynch, Michael Pfreundschuh
Journal: Blood
Blood (2011) 118 (3): 635–637.
https://doi.org/10.1182/blood-2011-01-331454
Published: 2011
Includes: Supplemental data
Journal Articles

A recombinant bispecific single-chain antibody, CD19 × CD3, induces rapid and high lymphoma-directed cytotoxicity by unstimulated T lymphocytes

Free
Anja Löffler, Peter Kufer, Ralf Lutterbüse, Florian Zettl, Peter T. Daniel, Jan M. Schwenkenbecher, Gert Riethmüller, Bernd Dörken, Ralf C. Bargou
Journal: Blood
Blood (2000) 95 (6): 2098–2103.
https://doi.org/10.1182/blood.V95.6.2098
Published: 2000