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Elizabeth O'Donnell
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Journal Articles

Single-cell immune profiling reveals enhanced immune fitness of endogenous and engineered T cells in patients with high-risk smoldering myeloma compared to Relapsed/Refractory myeloma following bispecific antibodies or CAR-T cell therapies.

Free
Francesco Corrado, Nayda Bidikian, Anna Bosch-Vilaseca, Yoshinobu Konishi, Rosa Toenges, Jean-Baptiste Alberge, Ting Wu, Sophie Magidson, Lorena Pantano, Michelle Aranha, Elizabeth Lightbody, Joseph Flinn, Michael Timonian, David Cordas Dos Santos, Rocio Montes De Oca, Tamar Lengil, Diego Vieyra, Mark Wildgust, Vicki Plaks, Denise De Wiest, Kevin De Braganca, Shonali Midha, Elizabeth O'Donnell, Yuxin Liu, Ashlee Sturtevant, Kenneth Anderson, Nikhil Munshi, Jerome Ritz, Omar Nadeem, Gad Getz, Romanos Sklavenitis-Pistofidis, Irene Ghobrial
Journal: Blood
Blood (2025) 146 (Supplement 1): 921.
https://doi.org/10.1182/blood-2025-921
Published: 2025
Journal Articles

A randomized phase II study of daratumumab, lenalidomide, ixazomib, and dexamethasone in transplant-ineligible or deferred patients with newly diagnosed multiple myeloma: Alliance Foundation Trial 41 (AFT-41)

Free
Andrew Yee, Elizabeth O'Donnell, Omar Nadeem, Garth Nelson, Tanya Wildes, Tondre Buck, Sascha Tuchman, Krishna Ghimire, Sarah Sinclair, Catherine Stewart, Paul Richardson, Saad Usmani, Noopur Raje
Journal: Blood
Blood (2025) 146 (Supplement 1): 4053.
https://doi.org/10.1182/blood-2025-4053
Published: 2025
Journal Articles

Results of the promise study from ~30,000 individuals screened for monoclonal gammopathies

Free
Sabine Allam, Sungjae Kim, Jean-Baptiste Alberge, Habib El-Khoury, Floris Chabrun, Jacqueline Perry, Katherine Padgett, Julia Colchie, Joseph Flinn, Grace Fleming, Rachel Choi, Kaitlin Bondi, Ciara Murphy, Sofia Wallin, Luca Bertamini, David Lee, Derek Troske, Dhananjay Sakrikar, David Barnidge, Stephen Harding, David Cordas Dos Santos, Romanos Sklavenitis-Pistofidis, Meletios Dimopoulos, Efstathios Kastritis, Irit Avivi, Wenlong Chen, Maureen Joffe, Elizabeth Karlson, Elizabeth O'Donnell, Omar Nadeem, Lorenzo Trippa, Catherine Marinac, Gad Getz, Irene Ghobrial
Journal: Blood
Blood (2025) 146 (Supplement 1): 403.
https://doi.org/10.1182/blood-2025-403
Published: 2025
Journal Articles

Spatial proteomics of the bone marrow reveals distinct Tumor–Immune niches in smoldering and relapsed myeloma and their remodeling in response to bispecific antibody and CAR-T therapy

Free
David Cordas Dos Santos, Kane Foster, Daniel Heilpern-Mallory, Sophia Schroeder, Yoshinobu Konishi, Maria-Theresa Silverio, Jacqueline Perry, Sophie Magidson, Diego Vieyra, Rocio Montes De Oca, Daniel Zangrando, Nina Lane, Adam Sperling, Eric Smith, Jacob Laubach, Elizabeth O'Donnell, Nikhil Munshi, Kenneth Anderson, Shonali Midha, Gad Getz, Omar Nadeem, Irene Ghobrial
Journal: Blood
Blood (2025) 146 (Supplement 1): 3921.
https://doi.org/10.1182/blood-2025-3921
Published: 2025
Journal Articles

Results of the Phase II d-PRISM study: Daratumumab in high-risk MGUS and low-risk smoldering myeloma

Free
Omar Nadeem, Michelle Aranha, Robert Redd, Michael Koontz, Jeffrey Matous, Andrew Yee, Jeffrey Zonder, Andrew Kin, Sophie Magidson, Elizabeth Lightbody, Ting Wu, Floris Chabrun, Jean-Baptiste Alberge, Ankit Dutta, Jacqueline Perry, Ashlee Sturtevant, Mahshid Rahmat, Junko Tsuji, Christine Davie, Caroline Ricciardi, Frances Arters, Marjorie Marto, Amy Goguen, Jacalyn Rosenblatt, Elizabeth O'Donnell, Jacob Laubach, Paul Richardson, Gad Getz, Lorenzo Trippa, Romanos Sklavenitis-Pistofidis, Irene Ghobrial
Journal: Blood
Blood (2025) 146 (Supplement 1): 1533.
https://doi.org/10.1182/blood-2025-1533
Published: 2025
Journal Articles

Identification of persister cells and evolution of tumor clones during immunotherapy and at minimal residual disease timepoints decoded by single-cell whole-genome sequencing in multiple myeloma

Free
Rosa Toenges, Jean-Baptiste Alberge, Tomoki Iemura, Francesco Corrado, Nayda Bidikian, David Cordas Dos Santos, Ankit Dutta, Romanos Sklavenitis-Pistofidis, Subear Hussein, Carlson Ketcham, Sophie Magidson, Shonali Midha, Elizabeth O'Donnell, Adam Sperling, Jacob Laubach, Kenneth Anderson, Eric Smith, Nikhil Munshi, Omar Nadeem, Gad Getz, Irene Ghobrial
Journal: Blood
Blood (2025) 146 (Supplement 1): 3930.
https://doi.org/10.1182/blood-2025-3930
Published: 2025
Journal Articles

COVID-19 Vaccine Responsiveness in Patients with Multiple Myeloma and Waldenström Macroglobulinemia

Free
Andrew R. Branagan, Matthew M Lei, Jenny S Maron, Andrew J Yee, Elizabeth O'Donnell, Jorge J. Castillo, Noopur S. Raje, Steven P Treon, Catherine A Flynn, Clifton C. Mo, Omar Nadeem, Paul G. Richardson, Cristina Panaroni, Kirsten Meid, Zachary S. Bernstein, Rebecca T. Lyons, Zachary R Hunter, Maria Luisa Guerrera, Marilyn T. Gammon, Kathleen J. Lively, Lisette Packer, Matthew Waterman, Raquel Gallagher, Boris Juleg, Galit Alter, Shayna Sarosiek
Journal: Blood
Blood (2021) 138 (Supplement 1): 3801.
https://doi.org/10.1182/blood-2021-154089
Published: 2021
Journal Articles

Molecular Features and Clinical Outcomes of Extramedullary Plasmacytomas

Free
Rie Nakamoto-Matsubara, Valentina Nardi, Cristina Panaroni, Keertik Fulzele, Tomoaki Mori, Rakesh Verma, Andrew J. Yee, Andrew R. Branagan, Elizabeth O'Donnell, Noopur S. Raje
Journal: Blood
Blood (2021) 138 (Supplement 1): 398.
https://doi.org/10.1182/blood-2021-152784
Published: 2021
Journal Articles

Updated Results from CARTITUDE-1: Phase 1b/2Study of Ciltacabtagene Autoleucel, a B-Cell Maturation Antigen-Directed Chimeric Antigen Receptor T Cell Therapy, in Patients With Relapsed/Refractory Multiple Myeloma

Free
Thomas Martin, Saad Z. Usmani, Jesús G. Berdeja, Andrzej Jakubowiak, Mounzer Agha, Adam D Cohen, Parameswaran Hari, David Avigan, Abhinav Deol, Myo Htut, Alexander Lesokhin, Nikhil C. Munshi, Elizabeth O'Donnell, A. Keith Stewart, Jordan M. Schecter, Jenna D. Goldberg, Carolyn C. Jackson, Tzu-Min Yeh, Arnob Banerjee, Alicia Allred, Enrique Zudaire, William Deraedt, Deepu Madduri, Yunsi Olyslager, Changwei Zhou, Lida Pacaud, Yi Lin, Sundar Jagannath
Journal: Blood
Blood (2021) 138 (Supplement 1): 549.
https://doi.org/10.1182/blood-2021-146060
Published: 2021
Journal Articles

Real-World Observations and Practical Considerations of Subcutaneous Daratumumab Administration in Multiple Myeloma

Free
E. Bridget Kim, Elizabeth O'Donnell, Andrew R. Branagan, Jill N. Burke, Cynthia C. Harrington, Emerentia Agyemang, Noopur S. Raje, Andrew J. Yee
Journal: Blood
Blood (2021) 138 (Supplement 1): 5018.
https://doi.org/10.1182/blood-2021-153751
Published: 2021
Journal Articles

CARTITUDE-1: Phase 1b/2 Study of Ciltacabtagene Autoleucel, a B-Cell Maturation Antigen-Directed Chimeric Antigen Receptor T Cell Therapy, in Relapsed/Refractory Multiple Myeloma

Free
Deepu Madduri, MD, Jesus G. Berdeja, MD, Saad Z. Usmani, MDMBBS,MBA, Andrzej Jakubowiak, MD PhD, Mounzer Agha, MD, Adam D. Cohen, MD, A. Keith Stewart, MBChB, Parameswaran Hari, MD MRCP, Myo Htut, MD, Elizabeth O'Donnell, MD, Nikhil C. Munshi, MD, David E. Avigan, MD, Abhinav Deol, MD, Alexander M. Lesokhin, MD, Indrajeet Singh, PhD, Enrique Zudaire, PhD, Tzu-Min Yeh, Alicia J. Allred, PhD, Yunsi Olyslager, MSc, Arnob Banerjee, MD, Jenna D. Goldberg, MD, Jordan M. Schecter, MD, Carolyn C. Jackson, MD MPH, William Deraedt, MSc, Sen Hong Zhuang, MD PhD, Jeffrey R. Infante, MD, Dong Geng, PhD, Xiaoling Wu, PhD, Marlene J. Carrasco, MD PhD MPH, Muhammad Akram, MD, Farah Hossain, PharmD, Syed Rizvi, MD, Frank Fan, MD PhD, Sundar Jagannath, MD, Yi Lin, MD PhD, Thomas Martin, III, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 22–25.
https://doi.org/10.1182/blood-2020-136307
Published: 2020
Journal Articles

TAK-573, an Anti-CD38/Attenuated Ifnα Fusion Protein, Has Clinical Activity and Modulates the Ifnα Receptor (IFNAR) Pathway in Patients with Relapsed/Refractory Multiple Myeloma

Free
Dan T. Vogl, MD, Jonathan L. Kaufman, MD, Sara A. Holstein, MDPhD, Omar Nadeem, MD, Elizabeth O'Donnell, MD, Kaveri Suryanarayan, MD, Sabrina Collins, Xavier Parot, MD, Maria Chaudhry, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 37–38.
https://doi.org/10.1182/blood-2020-141219
Published: 2020
Journal Articles

Analysis of Hospitalization and Readmissions after CAR T Cell Therapy

Free
Elizabeth O'Donnell, MD, Hao Deng, MD, Kyan Safavi, William Driscoll, MD, Milcho Nikolov, Andrew J Yee, MD, Noopur Raje, MD, Matthiew Frigault, MD MSc, Dusan Handiziar, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2301.
https://doi.org/10.1182/blood-2018-99-112254
Published: 2018
Journal Articles

Final Results of a Phase 2 Study of Modified Lenalidomide, Bortezomib, and Dexamethasone (RVD lite) in Transplant-Ineligible Multiple Myeloma

Free
Elizabeth O'Donnell, MD, Jacob Laubach, MD, Andrew J Yee, MD, Tianqi Chen, Carol Ann Huff, MD, Frank G. Basile, MD, Philip Wade, MD, Claudia Paba-Prada, MD, Irene M. Ghobrial, MD, Robert Schlossman, MD, Jill Burke, Harrington Cynthia, Kathleen Lively, Hannah Lyons, Nikhil Munshi, MD, Lorenzo Trippa, PhD, Kenneth C Anderson, MD, Paul G Richardson, MD, Noopur Raje, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3126.
https://doi.org/10.1182/blood.V130.Suppl_1.3126.3126
Published: 2017
Journal Articles

Ibrutinib Is Highly Active As First Line Therapy in Symptomatic Waldenstrom's Macroglobulinemia

Free
Steven P Treon, MDPhDFRCP, Joshua Gustine, Kirsten Meid, MPH, Toni Dubeau, NP, Patricia Severns, NP, Christopher Patterson, MAcc, Lian Xu, Guang Yang, PhD, Xia Liu, MD, Maria Demos, BS, Amanda Kofides, BS, Jiaji Chen, BS, Manit Munshi, MS, Nickolas Tsakmaklis, BA, Gloria Chan, MS, Andrew J Yee, MD, Noopur Raje, MD, Elizabeth O'Donnell, MD, Zachary Hunter, PhD, Jorge J. Castillo, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2767.
https://doi.org/10.1182/blood.V130.Suppl_1.2767.2767
Published: 2017
Journal Articles

Initial Results of a Phase 1/2a, Dose Escalation Study of PVX-410 Multi-Peptide Cancer Vaccine in Patients with Smoldering Multiple Myeloma (SMM)

Free
Michael (Luhua) Wang, MD, Ajay K. Nooka, MD MPH, Andrew J. Yee, MD, Sheeba K. Thomas, MD, Elizabeth O'Donnell, MD, Jatin Shah, MD, Donna M. Weber, MD, Jonathan L. Kaufman, MD, Sagar Lonial, MD, David Avigan, MD, Noopur Raje, MD
Journal: Blood
Blood (2014) 124 (21): 4737.
https://doi.org/10.1182/blood.V124.21.4737.4737
Published: 2014
Journal Articles

A Phase II Study of Modified Lenalidomide, Bortezomib, and Dexamethasone (RVD lite) for Transplant-Ineligible Patients with Newly Diagnosed Multiple Myeloma

Free
Elizabeth O'Donnell, MD, Jacob P. Laubach, MD, Andrew J Yee, MD, Carol Ann Huff, MD, Frank Basile, MD, Philip M. Wade, MD, Claudia E. Paba-Prada, MD, Irene M. Ghobrial, MD, Robert L Schlossman, MD, Nicole Couture, RN, Lauren Doherty, Hannah Lyons, RN, Caroline English, Nikhil Munshi, Kenneth C. Anderson, Paul G. Richardson, MD, Noopur Raje, MD
Journal: Blood
Blood (2014) 124 (21): 3454.
https://doi.org/10.1182/blood.V124.21.3454.3454
Published: 2014