1-20 of 201
Dirk Reinhardt
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Journal Articles

Independent, International Validation and Refinement of a Machine Learning Algorithm to Classify Acute Leukemia Using Routine Laboratory Features

Free
Amin T. Turki, Alberto Hernández Sánchez, Wellington Silva, Magdalena Karasek, Luca Guarnera, Koray Yalçin, Amir Enshaei, Marta Sobas, Dirk Reinhardt, Maria M Rivas, Deepak Kumar Mishra, Eduardo Rego, Ahmet Koc, Paola Núñez Medina, Maria Teresa Voso, Anthony Moorman, Felix Nensa, Merlin Engelke
Journal: Blood
Blood (2024) 144 (Supplement 1): 790.
https://doi.org/10.1182/blood-2024-207058
Published: 2024
Journal Articles

Comprehensive Analysis of Target and Immune Checkpoint Markers in Pediatric AML

Free
Stephanie Sendker, Jens Gehlen, Tabea Ziedrich, Evangelia Antoniou, Markus Schneider, Nils Von Neuhoff, Dirk Reinhardt, Lina Marie Hoffmeister
Journal: Blood
Blood (2024) 144 (Supplement 1): 4322.
https://doi.org/10.1182/blood-2024-208614
Published: 2024
Journal Articles

Significance of RT-qPCR-Based Measurable Residual Disease for Optimizing the Treatment of Pediatric Acute Myeloid Leukemia

Free
Evangelia Antoniou, Lina Marie Hoffmeister, Nils Von Neuhoff, Dirk Reinhardt, Markus Schneider, Stephanie Sendker
Journal: Blood
Blood (2024) 144 (Supplement 1): 228.
https://doi.org/10.1182/blood-2024-208718
Published: 2024
Journal Articles

Allogeneic Hematopoietic Stem Cell Transplantation in Pediatric Acute Myeloid Leukemia: Results of the AML BFM Study Group

Free
Eva Rettinger, Martin Hutter, Birte Karschen, Evangelia Antoniou, Peter Bader, Rita Beier, Birgit Burkhardt, Ursula Creutzig, Gabriele Escherich, Jan-Henning Klusmann, Peter Lang, Naghmeh Niktoreh, Martin G. Sauer, Stephanie Sendker, Dirk Reinhardt, Katharina Waack
Journal: Blood
Blood (2024) 144 (Supplement 1): 3548.
https://doi.org/10.1182/blood-2024-208311
Published: 2024
Journal Articles

Addition of Anti-T-Lymphocyte-Globuline As Graft Versus Host Disease Prophylaxis for Matched Unrelated Donors Equalizes Outcomes with Matched Sibling Donors: Results from the AML SCT-BFM 2007 Trial

Free
Martin G. Sauer, Peter Lang, Michael H Albert, Peter Bader, Ursula Creutzig, Matthias Eyrich, Johann Greil, Bernd Gruhn, Wolfgang Holter, Thomas Klingebiel, Bernhard Kremens, Christine Mauz-Körholz, Roland Meisel, Kirsten Mischke, Ingo Muller, Charlotte Marie Niemeyer, Christina Peters, Dirk Reinhardt, Birgit Burkhardt, Paul-Gerhardt Schlegel, Ansgar Schulz, Johanna Schrum, Petr Sedlacek, Brigitte Strahm, Wilhelm Woessmann, Rupert Handgretinger, Martin Zimmermann, Arndt Borkhardt
Journal: Blood
Blood (2024) 144 (Supplement 1): 3563.
https://doi.org/10.1182/blood-2024-200574
Published: 2024
Journal Articles

Treatment of Molecular Relapses in Pediatric AML Saves Toxicities Prior to Hematopoietic Stem Cell Transplantation (HSCT) - Results of AMoRe2017 Trial

Free
Amelie Polutta, Dirk Reinhardt, Andre Baruchel, Henrik Hasle, Franco Locatelli, C. Michel Zwaan, Michael Frühwald, Silke Westphal, Michael Dworzak, Heidrun Boztug, Gabriele Escherich, Thomas Lehrnbecher, Bianca F. Goemans, Brigitte Strahm, Markus Schneider, Lina Hoffmeister, Katharina Waack
Journal: Blood
Blood (2023) 142 (Supplement 1): 1521.
https://doi.org/10.1182/blood-2023-180820
Published: 2023
Journal Articles

Europeanpediatric Acute Leukemia (EuPAL) Registry

Free
Katarzyna Majstrowicz, Katharina Waack, Evangelia Antoniou, Naghmeh Niktoreh, Gwen Nichols, Laura Di Laurenzio, Michele S. Redell, Todd Cooper, E. Anders Kolb, Sarah K. Tasian, Franco Locatelli, C. Michel Zwaan, Dirk Reinhardt
Journal: Blood
Blood (2023) 142 (Supplement 1): 1496.
https://doi.org/10.1182/blood-2023-189684
Published: 2023
Journal Articles

Characteristics of FLT3 -ITD and Efficacy of Sorafenib Treatment in Pediatric AML: A Report from AML-BFM Study Group

Free
Evangelia Antoniou, Annika Puschnig, Lina Marie Hoffmeister, Amani Awada, Nils Von Neuhoff, Markus Schneider, Dirk Reinhardt, Naghmeh Niktoreh
Journal: Blood
Blood (2023) 142 (Supplement 1): 4217.
https://doi.org/10.1182/blood-2023-187465
Published: 2023
Journal Articles

APAL2020SC Pediatric Acute Leukemia (PedAL) Screening Trial - Developing New Therapies for Relapsed Leukemias

Free
Michele S. Redell, Todd A. Alonzo, Robert Gerbing, Jim Wang, Maureen M. O'Brien, Gwen Nichols, Laura Di Laurenzio, Sarah K. Tasian, C. Michel Zwaan, Dirk Reinhardt, E. Anders Kolb, Todd Cooper
Journal: Blood
Blood (2023) 142 (Supplement 1): 1492.
https://doi.org/10.1182/blood-2023-190947
Published: 2023
Journal Articles

Machine Learning Provides Individualized Prediction of Outcomes after First Complete Remission in Adult AML Patients - Results from the Harmony Platform

Free
Alberto Hernández Sánchez, Javier Martínez Elicegui, Marta Sobas, Eric Sträng, Axel Benner, María Abáigar, Gastone Castellani, Laura Tur, Peter J. M. Valk, Angela Villaverde Ramiro, Klaus H Metzeler, Raúl Azibeiro Melchor, Jurjen Versluis, Daniele Dall'Olio, Teresa González, Jesse M. Tettero, Joaquin Martinez-Lopez, Helena Fidalgo, Jorge Sierra, Frederik Damm, Ken I Mills, Soren Lehmann, Ian Thomas, Jiří Mayer, Christian Thiede, Maria Teresa Voso, Guillermo Sanz, Konstanze Döhner, Michael Heuser, Torsten Haferlach, Amin T. Turki, Dirk Reinhardt, Michel van Speybroeck, Renate Schulze-Rath, Martje Barbus, John E Butler, Jesús María Hernández-Rivas, Brian Huntly, Gert Ossenkoppele, Hartmut Döhner, Lars Bullinger
Journal: Blood
Blood (2023) 142 (Supplement 1): 62.
https://doi.org/10.1182/blood-2023-183029
Published: 2023
Journal Articles

Impact-AML: A European Master Framework for Cohort Studies and Pragmatic Clinical Trials in Relapse or Refractory Acute Myeloid Leukemia

Free
Giovanni Marconi, Petros Kountouris, Jiri Mayer, Lars Bullinger, Dirk Reinhardt, Pau Montesinos, Pietro Merli, Marco Vignetti, Jos Dumortier, Jesús María Hernández-Rivas, Michael Heuser, Rolandas Gerbutavicius, Antonio Francesco Maturo, Gianni D'Errico, Samantha Nier, Chiara Zingaretti, Irene Azzali, Federica Campacci, Maria Del Mar Mañú-Pereira, Franco Locatelli, Rüdiger Hehlmann, Dietger W. Niederwieser, Giovanni Martinelli
Journal: Blood
Blood (2023) 142 (Supplement 1): 1533.
https://doi.org/10.1182/blood-2023-184745
Published: 2023
Journal Articles

Nucleophosmin (NPM1) Type D Genotype Is Associated with Distinct Outcome in Acute Myeloid Leukemia - an AIEOP-BFM and COG-SWOG Intergroup Collaboration

Free
Martina Pigazzi, Claudia Tregnago, Rhonda E Ries, Maddalena Benetton, Todd A. Alonzo, Nicolas Duployez, Edwin Sonneveld, Jonas Abrahamsson, Linda Fogelstrand, Nils Von Neuhoff, Henrik Hasle, Dirk Reinhardt, Franco Locatelli, Soheil Meshinchi
Journal: Blood
Blood (2023) 142 (Supplement 1): 840.
https://doi.org/10.1182/blood-2023-181872
Published: 2023
Journal Articles

RUNX1 isoform disequilibrium promotes the development of trisomy 21–associated myeloid leukemia

Free
Sofia Gialesaki, Daniela Bräuer-Hartmann, Hasan Issa, Raj Bhayadia, Oriol Alejo-Valle, Lonneke Verboon, Anna-Lena Schmell, Stephanie Laszig, Enikő Regényi, Konstantin Schuschel, Maurice Labuhn, Michelle Ng, Robert Winkler, Christian Ihling, Andrea Sinz, Markus Glaß, Stefan Hüttelmaier, Sören Matzk, Lena Schmid, Farina Josepha Strüwe, Sofie-Katrin Kadel, Dirk Reinhardt, Marie-Laure Yaspo, Dirk Heckl, Jan-Henning Klusmann
Journal: Blood
Blood (2023) 141 (10): 1105–1118.
https://doi.org/10.1182/blood.2022017619
Published: 2023
Includes: Supplemental data
Journal Articles

RAS Pathway Alterations in Pediatric AML Patients

Free
Kevin Hai-Ning Lu, Lina Hoffmeister, Eser Orhan, Markus Schneider, Katharina Waack, Helmut Hanenberg, Nils von Neuhoff, Dirk Reinhardt
Journal: Blood
Blood (2022) 140 (Supplement 1): 6110–6111.
https://doi.org/10.1182/blood-2022-170747
Published: 2022
Journal Articles

Management and Outcome of Hyperleukocytosis As Early Complication in Childhood AML - an AML-BFM Experience

Free
Katharina Waack, Franziska Budeus, Evangelia Antoniou, Dirk Reinhardt
Journal: Blood
Blood (2022) 140 (Supplement 1): 6084–6085.
https://doi.org/10.1182/blood-2022-169455
Published: 2022
Journal Articles

Second Malignancy after Childhood AML Treatment - a Retrospective Analysis of the AML-BFM Stud

Free
Katharina Waack, Daniel Weber, Stephanie Sendker, Dirk Reinhardt
Journal: Blood
Blood (2022) 140 (Supplement 1): 6082–6083.
https://doi.org/10.1182/blood-2022-168829
Published: 2022
Journal Articles

Guiding Pups with Severe Hemophilia a and Their Parents from Diagnosis to a Full Prophylactic Schedule Mitigating the Risk of Bleed and the Risk for Inhibitor Formation - a Single Centre Approach

Free
Susan Halimeh, Hannelore Rott, Manuela Siebert, Günther Kappert, Dirk Reinhardt
Journal: Blood
Blood (2022) 140 (Supplement 1): 8472–8473.
https://doi.org/10.1182/blood-2022-168988
Published: 2022
Journal Articles

Revision of Complete Remission Criteria in Pediatric AML

Free
Evangelia Antoniou, Annika Puschnig, Katharina Waack, Carolin Augsburg, Christel Katerkamp, Denise Kondryn, Tabea Ziedrich, Nils von Neuhoff, Dirk Reinhardt, Stephanie Sendker
Journal: Blood
Blood (2022) 140 (Supplement 1): 1016–1017.
https://doi.org/10.1182/blood-2022-170648
Published: 2022
Journal Articles

Molecular Relapse in Pediatric AML: Clinical Relapse May be Predicted By Increasingin MRD Level - Experiences from Real-World Data in Patients with Inv(16), t(8;21), t(9;11), t(10;11) or NPM1

Free
Katharina Waack, Katharina Andernacht, Christiane Walter, Markus Schneider, Nils Von Neuhoff, Sophia Hahn, Amani Awada, Dirk Reinhardt
Journal: Blood
Blood (2022) 140 (Supplement 1): 6326–6327.
https://doi.org/10.1182/blood-2022-169495
Published: 2022
Journal Articles

ITCC-101/APAL2020D: A Randomized Phase 3 Trial of Fludarabine/Cytarabine/Gemtuzumab Ozogamycin with or without Venetoclax in Children with Relapsed Acute Myeloid Leukemia

Free
Sae Ishimaru, Gwenaëlle Gueguen, Seth E. Karol, Francisco J. Bautista Sirvent, Valeria Ceolin, Bianca F. Goemans, Marlous Bakker, Laura Di Laurenzio, Jennifer Lukin, Harm Van Tinteren, Gauri B. Sunkersett, Maika Onishi, Kristina Unnebrink, Dirk Reinhardt, Gwen L Nichols, E. Anders Kolb, C. Michel Zwaan
Journal: Blood
Blood (2022) 140 (Supplement 1): 3369–3370.
https://doi.org/10.1182/blood-2022-168818
Published: 2022