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Craig D Simpson
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Journal Articles

PIKfyve inhibition in myeloma disrupts autophagy and the lysosome, increasing MHC expression and cholesterol metabolism

Open Access
Cecilia Bonolo De Campos, Ruijuan He, Tessa Josephine Pelino, Dor David Abelman, Zhihua Li, Daniel K C Lee, Ding Yan Wang, Michael St. Paul, Jeffrey Bruce, Craig D Simpson, Leanne Wybenga-Groot, Michael F. Moran, Rodger E Tiedemann, Trevor Pugh, Tak W. Mak, Olga Issakova, Nikolai Sepetov, Suzanne Trudel, A Keith Stewart
Journal: Blood
Blood blood.2025030061.
https://doi.org/10.1182/blood.2025030061
Published: 2025
Includes: Supplemental data
Journal Articles

The antihelmintic flubendazole inhibits microtubule function through a mechanism distinct from Vinca alkaloids and displays preclinical activity in leukemia and myeloma

Free
Paul A. Spagnuolo, Jiayi Hu, Rose Hurren, Xiaoming Wang, Marcela Gronda, Mahadeo A. Sukhai, Ashley Di Meo, Jonathan Boss, Iman Ashali, Reza Beheshti Zavareh, Noah Fine, Craig D. Simpson, Sumaiya Sharmeen, Rob Rottapel, Aaron D. Schimmer
Journal: Blood
Blood (2010) 115 (23): 4824–4833.
https://doi.org/10.1182/blood-2009-09-243055
Published: 2010
Includes: Supplemental data
Journal Articles

The Antihelmintic Flubendazole Inhibits Microtubules through a Mechanism Distinct From Vinca Alkaloids and Displays Preclinical Activity in Leukemia and Myeloma.

Free
Paul A. Spagnuolo, PhD, Jiayi Hu, Rose Hurren, Ashley Di Meo, Jonathan Boss, Iman Ashali, Marcela Gronda, Xiaoming Wang, Reza Behesti Zavareh, Sumaiya Sharmeen, Noah Fine, Craig D Simpson, Robert Rottapel, MD, Aaron D. Schimmer, MD, PhD
Journal: Blood
Blood (2009) 114 (22): 1017.
https://doi.org/10.1182/blood.V114.22.1017.1017
Published: 2009