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Journal Articles

Large-scale dependency and drug screens characterize the therapeutic vulnerabilities of Multiple Myeloma with 1q+

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Romanos Sklavenitis-Pistofidis, Elizabeth D Lightbody, Mairead Reidy, Junko Tsuji, Jean-Baptiste Alberge, Michelle P Aranha, Daniel Lewis Heilpern-Mallory, Harvey G. Roweth, Daisy Huyng, Stephen Jun Fei Chong, Anna Y. Chung, Jeremy Zhang, Liam Hackett, Nicholas J Haradhvala, Ting Wu, Nang Kham Su, Brianna Berrios, Saveliy Belkin, Ankit K. Dutta, Ryan A Knudson, Carolyn Brandt, Patricia T. Greipp, Matthew S. Davids, Maria Papaioannou, Gad Getz, Irene M Ghobrial, Salomon Manier
Journal: Blood
Blood blood.2024025102.
https://doi.org/10.1182/blood.2024025102
Published: 2025
Includes: Supplemental data
Journal Articles

Progression signature underlies clonal evolution and dissemination of multiple myeloma

Free
Yu Jia Shen, Yuji Mishima, Jiantao Shi, Romanos Sklavenitis-Pistofidis, Robert A. Redd, Michele Moschetta, Salomon Manier, Aldo M. Roccaro, Antonio Sacco, Yu-Tzu Tai, Francois Mercier, Yawara Kawano, Nang Kham Su, Brianna Berrios, John G. Doench, David E. Root, Franziska Michor, David T. Scadden, Irene M. Ghobrial
Journal: Blood
Blood (2021) 137 (17): 2360–2372.
https://doi.org/10.1182/blood.2020005885
Published: 2021
Includes: Supplemental data
Journal Articles

Single-Cell RNA Sequencing Reveals Compromised Immune Microenvironment in Precursor Stages of Multiple Myeloma

Free
Oksana Zavidij, PhD, Nicholas Haradhvala, BA, Tarek H Mouhieddine, MD, Jihye Park, PhD, Romanos Pistofidis, MD, Mairead Reidy, PhD, Daisy Huynh, MS, Marzia Capelletti, PhD, Brianna Berrios, BS, Mahshid Rahmat, PhD, Mark Bustoros, MD, Chia-Jen Liu, MD, Meng Xiao He, AB, Yosef Maruvka, PhD, Bradley Rivotto, BS, Kalvis Hornburg, BA, Melissa Goldman, PhD, Eliezer Van Allen, MD, Steven A McCarroll, PhD, Jamil Azzi, MD, Gad Getz, PhD, Irene M. Ghobrial, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2603.
https://doi.org/10.1182/blood-2018-99-114145
Published: 2018
Journal Articles

Dissecting the Epigenetic Landscape of Smoldering, Newly Diagnosed and Relapsed Multiple Myeloma Revealed IRAK3 As a Marker of Disease Progression

Free
Mahshid Rahmat, PhD, Nicholas Haradhvala, BA, Romanos Sklavenitis-Pistofidis, MD, Jihye Park, PhD, Daisy Huynh, MS, Mark Bustoros, MD, Brianna Berrios, BS, Mairead Reidy, PhD, Adriana Perilla-Glen, Bradley Rivotto, BS, Kalvis Hornburg, BA, David M. Dorfman, MD, PhD, Jonathan D. Licht, MD, Gad Getz, PhD, Irene M. Ghobrial, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3896.
https://doi.org/10.1182/blood-2018-99-115046
Published: 2018
Journal Articles

Phase II Trial of the Combination of Ixazomib, Lenalidomide, and Dexamethasone in High-Risk Smoldering Multiple Myeloma

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Mark Bustoros, MD, Chia-jen Liu, MD, Kaitlen Reyes, NP, Kalvis Hornburg, BA, Kathleen Guimond, RN, Rachel Styles, Alexandra Savell, BS, Brianna Berrios, BS, Diane Warren, Henry Dumke, BS, Bradley Rivotto, BS, Patrick Henrick, BS, Emily Scranton, NP, Houry Leblebjian, PharmD, Kirsten Meid, MPH, Robert L. Schlossman, MD, Nikhil Munshi, MD, Jacob Laubach, MD, Kenneth C. Anderson, MD, Paul Richardson, Irene M. Ghobrial, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 804.
https://doi.org/10.1182/blood-2018-99-117871
Published: 2018
Journal Articles

Phase II Trial of Combination of Elotuzumab, Lenalidomide, and Dexamethasone in High-Risk Smoldering Multiple Myeloma

Free
Chia-jen Liu, MD, Irene M. Ghobrial, MD, Mark Bustoros, MD, Kaitlen Reyes, NP, Kalvis Hornburg, BA, Ashraf Z. Badros, MD, James J. Vredenburgh, MD, Adam Boruchov, MD, Jeffrey V Matous, MD, Aaron Caola, BS, Bradley Rivotto, BS, Alexandra Savell, BS, Patrick Henrick, BS, Claudia E. Paba-Prada, MD, Robert L. Schlossman, MD, Jacob Laubach, MD, Jacalyn Rosenblatt, MD, Andrew J Yee, MD, Omar Nadeem, MD, Rodrigo O. Maegawa, MD, Andrzej Jakubowiak, MD PhD, Saad Z. Usmani, MD, Manisha Bhutani, MD, Joseph Cappuccio, BS, Brianna Berrios, BS, Kimberly Noonan, NP, Oksana Zavidij, PhD, Tarek H Mouhieddine, MD, Cody J Boehner, Carl-Jannes Neuse, Karma Ziad Salem, MD, Mairead Reidy, PhD, Jihye Park, PhD, Michael Agius, PhD, Mahshid Rahmat, PhD, Salomon Manier, MD PhD, Divaya Bhutani, MD, Jeffrey A Zonder, MD, Nikhil Munshi, MD, Daniel Auclair, PhD, Kenneth Anderson, MD, Paul Richardson
Journal: Blood
Blood (2018) 132 (Supplement 1): 154.
https://doi.org/10.1182/blood-2018-154
Published: 2018
Journal Articles

Deciphering Clonal Evolution and Dissemination of Multiple Myeloma Cells In Vivo

Free
Yujia Shen, PhD, Yuji Mishima, Jiantao Shi, PhD, Michele Moschetta, MD, Salomon Manier, MD PhD, Aldo M. Roccaro, MDPhD, Francois Mercier, MD FRCPC, Satoshi Takagi, PhD, Yawara Kawano, MD PhD, Shokichi Tsukamoto, MD PhD, Ilyas Sahin, Antonio Sacco, Daisy Huynh, MS, Brianna Berrios, BS, Romanos Pistofidis, MD, Jihye Park, PhD, Oksana Zavidij, PhD, Sabrin Tahri, MD, John G Doench, PhD, David E. Root, PhD, Franziska Michor, PhD, David T. Scadden, MD, Irene M. Ghobrial, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 55.
https://doi.org/10.1182/blood-2018-99-113916
Published: 2018
Journal Articles

In Vivo Modeling of Clonal Competition Using CRISPR-Based Gene Editing Reveals Novel Fitness Variables in Multiple Myeloma

Free
Yujia Shen, PhD, Salomon Manier, MD PhD, Sabrin Tahri, MD, Brianna Berrios, BS, Oksana Zavidij, PhD, Jihye Park, PhD, Romanos Pistofidis, MD, Irene M. Ghobrial, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 57.
https://doi.org/10.1182/blood-2018-99-113842
Published: 2018
Journal Articles

A Rationally Designed Novel Polymer for Safe and Synergistic Delivery of High Dose Bortezomib, Pomalidomide/Lenalidomide, and Dexamethasone for Multiple Myeloma

Free
Alexandre Detappe, PhD, Hung Nguyen, Clelia Mathieu, MSc, Yivan Jiang, PhD, Michael Agius, PhD, Oksana Zavidij, PhD, Brianna Berrios, BS, Yujia Shen, PhD, Jeremiah A Johnson, PhD, Paiman Peter Ghoroghchian, MD PhD, Irene M. Ghobrial, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4681.
https://doi.org/10.1182/blood-2018-99-116517
Published: 2018