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Brian A. Walker
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Journal Articles

A multiomic analysis of Waldenström macroglobulinemia defines distinct disease subtypes

Available to Purchase
Dylan C Gagler, Hussein Ghamlouch, Di Zhang, Patrick Blaney, Avital Tenenbaum, James Blake Langton, Marine Armand, Alexandre Eeckhoutte, Amina Joudat, Michaël Degaud, Michela Esposito, Gaurav Varma, Yubao Wang, Sanghoon Lee, Sanxiong Liu, Oscar B Lahoud, David Kaminetzky, Marc J. Braunstein, Louis Williams, Florence Nguyen-Khac, Brian A Walker, Damien Roos-Weil, Faith E Davies, Olivier A Bernard, Gareth J Morgan
Journal: Blood
Blood blood.2024028164.
https://doi.org/10.1182/blood.2024028164
Published: 2025
Includes: Supplemental data
Journal Articles

Subclone-Aware Prognosis across Stages of Myeloma Progression and Course of Treatment

Free
Travis Johnson, Enze Liu, Ke Yang, Parvathi Sudha, Vivek S. Chopra, Faiza Zafar, Rafat Abonour, Brian A. Walker
Journal: Blood
Blood (2024) 144 (Supplement 1): 4657.
https://doi.org/10.1182/blood-2024-211489
Published: 2024
Journal Articles

A Phase III, Randomized Study of Daratumumab, Cyclophosphamide, Bortezomib and Dexamethasone (DARA-VCD) Induction Followed By Autologous Stem Cell Transplant or Dara-VCD Consolidation and Daratumumab Maintenance in Patients with Newly Diagnosed AL Amyloidosis

Free
Patrick Hagen, Surbhi Sidana, Terri L. Parker, Brian A. Walker, Vaishali Sanchorawala, Jeffrey A. Zonder, Taxiarchis Kourelis, Anita D'Souza, Heather J. Landau, Adam Rosenthal, Antje Hoering, Sikander Ailawadhi, Robert Z. Orlowski
Journal: Blood
Blood (2024) 144 (Supplement 1): 3309.1.
https://doi.org/10.1182/blood-2024-208227
Published: 2024
Journal Articles

Multiomics Data Integration in the Complete Myeloma Genome Reveals Frequent Centromeric Rearrangements and Their Epigenomic Consequences

Free
Aneta Mikulasova, Enze Liu, Nathan Becker, Parvathi Sudha, Rafat Abonour, Brian A. Walker
Journal: Blood
Blood (2024) 144 (Supplement 1): 768.
https://doi.org/10.1182/blood-2024-200043
Published: 2024
Journal Articles

A Multiomic Analysis of Waldenstrom's Macroglobulinemia Identifies Three Subtypes of Disease Based on Impaired Plasma Cell Differentiation

Free
Dylan C Gagler, Hussein Ghamlouch, Di Zhang, Patrick Blaney, Marine Armand, Alexandre Eeckhoutte, Amina Joudat, Michael Degaud, Michela Esposito, Gaurav Varma, Yubao Wang, Sanxiong Liu, Oscar B Lahoud, David Kaminetzsky, Marc J Braunstein, Florence Nguyen-Khac, Brian A. Walker, Damien Roos-Weil, Faith E Davies, Olivier Bernard, Gareth Morgan
Journal: Blood
Blood (2024) 144 (Supplement 1): 857.
https://doi.org/10.1182/blood-2024-210654
Published: 2024
Journal Articles

Reconstructing Catastrophic Chromothripsis Events Using Multiomic Data Reveals Their Functional Impact in Multiple Myeloma

Free
Enze Liu, Nathan Becker, Parvathi Sudha, Aneta Mikulasova, Rafat Abonour, Brian A. Walker
Journal: Blood
Blood (2024) 144 (Supplement 1): 4644.
https://doi.org/10.1182/blood-2024-205167
Published: 2024
Journal Articles

Non-Hotspot DIS3 Mutations in Multiple Myeloma Result in Loss of Function Accompanied By Transcriptional and Proteomic Dysregulation

Free
Ceanne Elliott, Enze Liu, Nathan Becker, Parvathi Sudha, Oumaima Jaouadi, Brian A. Walker
Journal: Blood
Blood (2024) 144 (Supplement 1): 4667.
https://doi.org/10.1182/blood-2024-207336
Published: 2024
Journal Articles

Novel PD-L1 Blocking Peptide with Mitochondrial Targeting Sequence: A Strategy to Counteract Resistance in T-Cell Immunotherapy for Myeloma

Free
Smriti Gurung, Colin Crean, David Lloyd Halladay, Judith L. Anderson, Rafat Abonour, Brian A. Walker, Kelvin P. Lee, John Mitchell Chirgwin, Attaya Suvannasankha
Journal: Blood
Blood (2024) 144 (Supplement 1): 6861.
https://doi.org/10.1182/blood-2024-211787
Published: 2024
Journal Articles

Mutationally Enriched Regions of the Non-Coding Genome Harbor Functionally Impactful Mutations That Dysregulate Key Genes Involved in Multiple Myeloma Pathogenesis

Free
Patrick Blaney, Kylee H Maclachlan, Marios Papadimitriou, Aneta Mikulasova, Dylan C Gagler, Marc J Braunstein, Oscar B Lahoud, David Kaminetzky, Yubao Wang, Sanxiong Liu, Di Zhang, Anthony Cirrincione, Alexandra Maria Poos, Bachisio Ziccheddu, Marcella Kaddoura, Monika Chojnacka, Benjamin Diamond, Neha Korde, Alexander M. Lesokhin, Saad Z. Usmani, Leo Rasche, Elias K. Mai, Marc S. Raab, Niels Weinhold, Elizabeth E. Brown, Nicolas Robine, Leif Bergsagel, Brian A. Walker, Ola Landgren, Francesco Maura, Faith E Davies, Gareth Morgan
Journal: Blood
Blood (2024) 144 (Supplement 1): 4655.
https://doi.org/10.1182/blood-2024-211012
Published: 2024
Journal Articles

Phylogenetic Analysis Reveals Distinct Evolutionary Patterns in Multiple Myeloma Patient Derived Xenografts

Free
Nathan Becker, Enze Liu, Parvathi Sudha, Riya Sharma, Travis Johnson, Aneta Mikulasova, Rafat Abonour, Brian A. Walker
Journal: Blood
Blood (2024) 144 (Supplement 1): 1882.
https://doi.org/10.1182/blood-2024-203953
Published: 2024
Journal Articles

Targeting Loss of the Tumor Suppressor TENT5C in Multiple Myeloma

Free
Oumaima Jaouadi, Nathan Becker, Enze Liu, Meng Jingwei, Brian A. Walker
Journal: Blood
Blood (2023) 142 (Supplement 1): 3297.
https://doi.org/10.1182/blood-2023-190217
Published: 2023
Journal Articles

Prospective Molecular Characterization of Multiple Myeloma Patient Samples Identifies High-Risk Patients and Informs Treatment Sequences through Resistance Mechanisms to Immunotherapies

Free
Phillip Pham, Parvathi Sudha, Lin Wang, Wen Niu, Cameron Morgan, Cameron Ligocki, Ramzi Al-Azzawi, Reynold Ly, Francesco Vetrini, Magdalena Czader, Marwan Tayeh, Mohammad Abu Zaid, Kelvin P. Lee, Attaya Suvannasankha, Rafat Abonour, Brian A. Walker
Journal: Blood
Blood (2023) 142 (Supplement 1): 4738.
https://doi.org/10.1182/blood-2023-180116
Published: 2023
Journal Articles

Somatic Hypermutation in Enhancer Regions Shapes Non-Coding Myeloma Genome, Generating DNA Breaks and Driving Etiology through Mutation and Structural Variation

Free
Patrick Blaney, Brian A. Walker, Aneta Mikulasova, Dylan Gagler, Bachisio Ziccheddu, Benjamin Diamond, Yubao Wang, Liming Hou, Sanxiong Liu, Alexandra Maria Poos, Anthony Cirrincione, Kylee H Maclachlan, Elias K. Mai, Hartmut Goldschmidt, Saad Z Usmani, Marc S. Raab, Niels Weinhold, Ola Landgren, Faith E. Davies, Francesco Maura, Gareth J. Morgan
Journal: Blood
Blood (2023) 142 (Supplement 1): 1401.
https://doi.org/10.1182/blood-2023-190473
Published: 2023
Journal Articles

Unraveling Diverse Mechanisms of Complex Structural Variant Interactions through Multiomic Data in Multiple Myeloma

Free
Enze Liu, Nathan Becker, Parvathi Sudha, Aneta Mikulasova, Mohammad Abu Zaid, Attaya Suvannasankha, Kelvin P. Lee, Rafat Abonour, Brian A. Walker
Journal: Blood
Blood (2023) 142 (Supplement 1): 641.
https://doi.org/10.1182/blood-2023-186262
Published: 2023
Journal Articles

Synergistic Effects of Type I PRMT1 and Type II PRMT5 Inhibitors Against Multiple Myeloma

Free
Hong Phuong Nguyen, Enze Liu, Brian A. Walker, Ngoc Tung Tran
Journal: Blood
Blood (2023) 142 (Supplement 1): 6593.
https://doi.org/10.1182/blood-2023-173852
Published: 2023
Journal Articles

Investigating the Functional Impact of CRBN Mutations on Response to IMiD/Celmod Agents in Myeloma

Free
Yakinthi Chrisochoidou, Yann-Vai LeBihan, Salomon Morales, Shannon Martin, Brian A. Walker, Yigen Li, Sarah Bird, Charlotte Pawlyn
Journal: Blood
Blood (2023) 142 (Supplement 1): 753.
https://doi.org/10.1182/blood-2023-179986
Published: 2023
Journal Articles

The Oligosaccharyltransferase Complex: A Novel Vulnerability in Multiple Myeloma

Free
Hong Phuong Nguyen, Anh Quynh Le, Enze Liu, Brian A. Walker, Ngoc Tung Tran
Journal: Blood
Blood (2023) 142 (Supplement 1): 4664.
https://doi.org/10.1182/blood-2023-178060
Published: 2023
Journal Articles

Individualized Treatment-Adjusted Risk Stratification in Newly Diagnosed Multiple Myeloma

Free
Francesco Maura, Arjun Raj Rajanna, Andriy Derkach, Bachisio Ziccheddu, Niels Weinhold, Kylee H Maclachlan, Benjamin Diamond, Faith E. Davies, Eileen Boyle, Brian A. Walker, Alexandra M Poos, Malin Hultcrantz, Ariosto Siqueira Silva, Oliver Hampton, Jamie Teer, Niccolò Bolli, Graham Jackson, Martin F. Kaiser, Charlotte Pawlyn, Gordon Cook, Dennis Verducci, Dickran Kazandjian, Frits van Rhee, Saad Usmani, Ken H. Shain, Marc S Raab, Gareth J. Morgan, Ola Landgren
Journal: Blood
Blood (2022) 140 (Supplement 1): 1561–1563.
https://doi.org/10.1182/blood-2022-160215
Published: 2022
Journal Articles

The Frequency of Alternative Splicing in Multiple Myeloma Is Determined By the Non-Homologous End Joining Pathway

Free
Enze Liu, Nathan Becker, Parvathi Sudha, Chuanpeng Dong, Yunlong Liu, Jonathan J Keats, Gareth J. Morgan, Brian A. Walker
Journal: Blood
Blood (2022) 140 (Supplement 1): 4259–4260.
https://doi.org/10.1182/blood-2022-167322
Published: 2022
Journal Articles

The Impact of Autologous Stem Cell Transplantation on the Genetics of High-Risk Relapsed Multiple Myeloma

Free
Mohamed Shahin, Charlotte Pawlyn, Niels Weinhold, Timothy Cody Ashby, Brian A. Walker, Christopher P. Wardell, David Cairns, Tom Menzies, Walter Martin Gregory, Martin F. Kaiser, Gordon Cook, Mark T Drayson, Roger G Owen, Graham Jackson, Faith E Davies, Gareth J. Morgan, John R Jones
Journal: Blood
Blood (2022) 140 (Supplement 1): 4232–4233.
https://doi.org/10.1182/blood-2022-169628
Published: 2022