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Barbara F. Eichhorst
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Journal Articles

Hitting the Therapeutic Bullseye with Targeted Therapy for Patients with Chronic Lymphocytic Leukemia

Available to Purchase
William G. Wierda, Barbara F. Eichhorst, Michael J Hallek
Journal: Blood
Blood blood.2025028570.
https://doi.org/10.1182/blood.2025028570
Published: 2025
Journal Articles

International Consensus Statement on Diagnosis, Evaluation, and Research of Richter Transformation: the ERIC Recommendations

Free
Adam S Kittai, Monia Marchetti, Othman Al-Sawaf, Ohad Benjamini, Alexey V Danilov, Matthew S. Davids, Barbara F. Eichhorst, Toby A. Eyre, Anna Maria Frustaci, Michael J Hallek, Paul Joseph Hampel, Yair Herishanu, Rodney John Hicks, Arnon P. Kater, Rebecca L. King, José-Ignacio Ignacio Martín-Subero, Carolyn Owen, Erin M. Parry, Maurilio Ponzoni, Davide Rossi, Tanya Siddiqi, Stephan Stilgenbauer, Constantine S. Tam, Elisa ten Hacken, Philip A Thompson, William G. Wierda, Gianluca Gaidano, Jennifer A. Woyach, Paolo Ghia
Journal: Blood
Blood blood.2024028064.
https://doi.org/10.1182/blood.2024028064
Published: 2025
Includes: Supplemental data
Journal Articles

Efficacy and Safety of Acalabrutinib Treatment in Very Old (≥80y) and/or Frail Patients with Chronic Lymphocytic Leukemia (CLL) - Primary Endpoint Analysis of the Phase II CLL-Frail Trial

Free
Florian Simon, Rudy Ligtvoet, Jan-Paul Bohn, Thomas Noesslinger, Julia Von Tresckow, Ruediger Liersch, Tobias Gaska, Kathleen Jentsch-Ullrich, Michael Gärtner, Thomas Wolff, Ingo Schwaner, Dominik Wolf, Christof Schneider, Ursula Vehling-Kaiser, Matthias Ritgen, Christian Spoer, Michael J. Eckart, Thomas Decker, Geothy Chakupurakal, Björn Schöttker, Jens Kisro, Janina Stumpf, Eugen Tausch, Stephan Stilgenbauer, Karl-Anton Kreuzer, Sandra Robrecht, Anna Maria Fink, Moritz Fürstenau, Kirsten Fischer, Valentin Goede, Michael Hallek, Barbara F. Eichhorst
Journal: Blood
Blood (2024) 144 (Supplement 1): 4618.
https://doi.org/10.1182/blood-2024-200848
Published: 2024
Journal Articles

Telomere Length Associations with Characteristics and Outcome in Patients Treated with Venetoclax-Based First-Line Combinations in the GAIA/CLL13 Study

Free
Billy Jebaraj, Eugen Tausch, Deyan Y. Yosifov, Christof Schneider, Moritz Fürstenau, Can Zhang, Sandra Robrecht, Caspar da Cunha-Bang, Mark-David Levin, Philipp Bernhard Staber, Tamar Tadmor, Patrick Thornton, Michael Gregor, Anna Maria Fink, Kirsten Fischer, Matthias Ritgen, Michael Hallek, Arnon P. Kater, Carsten Utoft Niemann, Barbara F. Eichhorst, Stephan Stilgenbauer
Journal: Blood
Blood (2024) 144 (Supplement 1): 4626.
https://doi.org/10.1182/blood-2024-204852
Published: 2024
Journal Articles

Polyfunctional Effector PD-1 + CD8 + T Cells and M1 Macrophages Promote Immune Checkpoint Blockade Response in Richter Syndrome Mouse Models

Free
Elisa Ten Hacken, Johan Gustafsson, Chiara Tomasoni, Gabriela Brunsting Hoffmann, Kayla Cruz, Wesley S Lu, Shuqiang Li, Nicholas Haradhvala, Connor Johnson, Stephanie Deng, Xia Bu, Donna S. Neuberg, Othman Al-Sawaf, Barbara F. Eichhorst, Clare Sun, Erin M. Parry, Gordon J. Freeman, Gad Getz, Catherine J. Wu
Journal: Blood
Blood (2024) 144 (Supplement 1): 761.
https://doi.org/10.1182/blood-2024-201006
Published: 2024
Journal Articles

Fixed-Duration Acalabrutinib Plus Venetoclax with or without Obinutuzumab Versus Chemoimmunotherapy for First-Line Treatment of Chronic Lymphocytic Leukemia: Interim Analysis of the Multicenter, Open-Label, Randomized, Phase 3 AMPLIFY Trial

Free
Jennifer R. Brown, John F. Seymour, Wojciech Jurczak, Andrew Aw, Malgorzata Wach, Arpad Illes, Alessandra Tedeschi, Carolyn Owen, Alan P Skarbnik, Daniel Lysak, Ki-Seong Eom, Martin Šimkovič, Miguel Arturo Pavlovsky, Arnon P. Kater, Barbara F. Eichhorst, Kara Miller, Veerendra Munugalavadla, Ting Yu, Marianne de Borja, Paolo Ghia
Journal: Blood
Blood (2024) 144 (Supplement 1): 1009.
https://doi.org/10.1182/blood-2024-200701
Published: 2024
Journal Articles

In-Depth Immune and Metabolic Profiling of GAIA/CLL13 Patients to Uncover Treatment-Specific Changes to the T-Cell Compartment

Free
Chaja Feige Jacobs, Yannick D'Hargues, Sandra Robrecht, Moritz Fürstenau, Kirsten Fischer, Anna Maria Fink, Stephan Stilgenbauer, Christof Schneider, Eugen Tausch, Carsten Utoft Niemann, Caspar da Cunha-Bang, Julie Dubois, Ellen Van Der Spek, Andre Vlot, Yorick Sandberg, Mark-David Levin, Michael Hallek, Barbara F. Eichhorst, Arnon P. Kater, Fleur S. Peters
Journal: Blood
Blood (2024) 144 (Supplement 1): 1846.
https://doi.org/10.1182/blood-2024-209692
Published: 2024
Journal Articles

Clonal Hematopoiesis in Patients with Chronic Lymphocytic Leukemia Treated with Fixed-Duration Venetoclax-Obinutuzumab or Chlorambucil-Obinutuzumab: Insights from the Randomized CLL14 Trial

Free
Othman Al-Sawaf, Benjamin N. Locher, Friederike Christen, Sandra Robrecht, Can Zhang, Anna Maria Fink, Eugen Tausch, Christof Schneider, Matthias Ritgen, Karl Anton Kreuzer, Coral Fustero, Raphael Hablesreiter, John F. Seymour, Piers Blombery, Lars Bullinger, Brenda Chyla, Hyun Yong Jin, Yanwen Jiang, Stephan Stilgenbauer, Barbara F. Eichhorst, Michael J. Hallek, Kirsten Fischer, Frederik Damm
Journal: Blood
Blood (2024) 144 (Supplement 1): 4613.
https://doi.org/10.1182/blood-2024-208727
Published: 2024
Journal Articles

Biallelic Deletion 13q in Chronic Lymphocytic Leukemia Treated with Targeted Agents

Free
Malte Knöll, Rashmi Priyadharshini Dheenadayalan, Deyan Y. Yosifov, Jialei Qi, Christof Schneider, Felix Seyfried, Lueder Hinrich Meyer, Paula Cramer, Julia Von Tresckow, Michael Hallek, Barbara F. Eichhorst, Eugen Tausch, Stephan Stilgenbauer, Billy Jebaraj
Journal: Blood
Blood (2024) 144 (Supplement 1): 4608.
https://doi.org/10.1182/blood-2024-204910
Published: 2024
Journal Articles

Informative Censoring in Randomized First-Line Trials of Chronic Lymphocytic Leukemia

Free
Florian Simon, Rudy Ligtvoet, Moritz Fürstenau, Petra Langerbeins, Anna Maria Fink, Julia Von Tresckow, Paula Cramer, Christian Bjørn Poulsen, Thomas Illmer, Lothar Müller, Ursula Vehling-Kaiser, Michael J. Eckart, Liliya Sivcheva, Javier Loscertales, Kathleen Jentsch-Ullrich, Holger F. Hebart, Mark-David Levin, Caspar Da Cunha-Bang, Nadine Kutsch, Eugen Tausch, Christof Schneider, Stephan Stilgenbauer, Sandra Robrecht, Arnon P. Kater, Carsten Utoft Niemann, Kirsten Fischer, Michael Hallek, Barbara F. Eichhorst, Othman Al-Sawaf
Journal: Blood
Blood (2024) 144 (Supplement 1): 6799.
https://doi.org/10.1182/blood-2024-203673
Published: 2024
Journal Articles

Impact of Ibrutinib on Quality of Life in Patients with Early-Stage, Asymptomatic Chronic Lymphocytic Leukemia: Results from the Phase III CLL12 Trial

Free
Ellinor Goergen, Sandra Robrecht, Adam Giza, Can Zhang, Pascal Nieper, Florian Simon, Paula Cramer, Moritz Fürstenau, Othman Al-Sawaf, Nadine Kutsch, Anna Maria Fink, Ursula Vehling-Kaiser, Lothar Müller, Michael J. Eckart, Rudolf Schlag, Werner Freier, Tobias Gaska, Christina Balser, Marcel Reiser, Martina Beate Stauch, Clemens-Martin Wendtner, Eugen Tausch, Christof Schneider, Kirsten Fischer, Stephan Stilgenbauer, Barbara F. Eichhorst, Michael Hallek, Petra Langerbeins
Journal: Blood
Blood (2024) 144 (Supplement 1): 1859.
https://doi.org/10.1182/blood-2024-200903
Published: 2024
Journal Articles

Patient-Reported Quality of Life Outcomes with Venetoclax-Based First-Line Combinations in CLL: An Analysis from the Phase 3 GAIA/CLL13 Trial

Free
Moritz Fürstenau, Emelie Curovic Rotbain, Laura Eurelings, Sandra Robrecht, Julia Von Tresckow, Adam Giza, Michael Gregor, Patrick Thornton, Philipp Bernhard Staber, Tamar Tadmor, Vesa Lindström, Gunnar Juliusson, Ann Janssens, Christof Schneider, Thomas Noesslinger, Martin Andres, Adrian Schmidt, Elisabeth Vandenberghe, Lev Shvidel, Christian Bjørn Poulsen, Henrik Frederiksen, Caspar Da Cunha-Bang, Kourosh Lotfi, Rogier Mous, Martine E.D. Chamuleau, Ka Lung Wu, Margriet Oosterveld, Jesus Duque-Afonso, Christian Bogner, Thomas Wolff, Johannes Schetelig, Ursula Vehling-Kaiser, Christoph van Roye, Nadine Kutsch, Anna Maria Fink, Kirsten Fischer, Emily Holmes, Matthias Ritgen, Eugen Tausch, Stephan Stilgenbauer, Michael J. Hallek, Arnon P. Kater, Carsten Utoft Niemann, Mark-David Levin, Barbara F. Eichhorst
Journal: Blood
Blood (2024) 144 (Supplement 1): 3238.
https://doi.org/10.1182/blood-2024-198917
Published: 2024
Journal Articles

Venetoclax May Overcome the Prognostic Disadvantage of Short Telomeres Regarding Progression Free Survival in Previously Untreated CLL Patients with Coexisting Conditions: A Study By the German CLL Study Group (GCLLSG)

Free
Lukas Peter Frenzel, Laura Beckmann, Sandra Robrecht, Can Zhang, Anna Maria Fink, Othman Al-Sawaf, Christof Schneider, Brenda Chyla, Hyun Yong Jin, Yanwen Jiang, Tim H. H. Brummendorf, Michael Hallek, Barbara F. Eichhorst, Kirsten Fischer, Fabian Beier, Susanne Isfort
Journal: Blood
Blood (2024) 144 (Supplement 1): 3250.
https://doi.org/10.1182/blood-2024-200075
Published: 2024
Journal Articles

MRD-Guided Zanubrutinib, Venetoclax and Obinutuzumab after an Optional Debulking with Bendamustine in Patients with Relapsed/Refractory Chronic Lymphocytic Leukemia: Primary Endpoint Analysis of the Phase 2 CLL2-Bzag Study

Free
Moritz Furstenau, Adam Giza, Christof Schneider, Eugen Tausch, Sandra Robrecht, Matthias Ritgen, Jörg Bittenbring, Holger F. Hebart, Björn Schöttker, Anna Lena Illert, Ullrich Graeven, Andrea Stoltefuss, Bernhard Heinrich, Robert Eckert, Anna-Maria Fink, Janina Stumpf, Florian Simon, Kirsten Fischer, Othman Al-Sawaf, Petra Langerbeins, Fanni Kleinert, Jonathan Weiss, Karl-Anton Kreuzer, Anke Schilhabel, Monika Brüggemann, Barbara F. Eichhorst, Stephan Stilgenbauer, Michael Hallek, Paula Cramer
Journal: Blood
Blood (2023) 142 (Supplement 1): 1897.
https://doi.org/10.1182/blood-2023-173707
Published: 2023
Journal Articles

Genetic markers and ibrutinib vs placebo treatment in early stage chronic lymphocytic leukemia -results from the GCLLSG CLL12 trial

Free
Armin Riecke, Eugen Tausch, Deyan Y. Yosifov, Christof Schneider, Sandra Robrecht, Adam Giza, Lothar Müller, Ursula Vehling-Kaiser, Michael J. Eckart, Werner Freier, Björn Schöttker, Tobias Gaska, Marcel Reiser, Anna-Maria Fink, Barbara F. Eichhorst, Kirsten Fischer, Michael Hallek, Petra Langerbeins, Stephan Stilgenbauer
Journal: Blood
Blood (2023) 142 (Supplement 1): 199.
https://doi.org/10.1182/blood-2023-180558
Published: 2023
Journal Articles

IGLV3-21 R110 Is a Prognostic Marker for Early Stage CLL Patients Under Ibrutinib Treatment or Watch & Wait: Results from the Double-Blind, Randomized, Placebo-Controlled GCLLSG CLL12 Trial

Free
Deyan Y. Yosifov, Sandra Robrecht, Adam Giza, Armin Riecke, Christof Schneider, Billy Jebaraj, Hassan Jumaa, Marc Young, Lothar Müller, Ursula Vehling-Kaiser, Michael J. Eckart, Werner Freier, Björn Schöttker, Tobias Gaska, Marcel Reiser, Anna-Maria Fink, Kirsten Fischer, Barbara F. Eichhorst, Michael Hallek, Petra Langerbeins, Stephan Stilgenbauer, Eugen Tausch
Journal: Blood
Blood (2023) 142 (Supplement 1): 1903.
https://doi.org/10.1182/blood-2023-179767
Published: 2023
Journal Articles

Response to Subsequent Novel Therapies and Time to Second Progression-Free Survival Event in the MURANO Trial in Patients with Relapsed/Refractory Chronic Lymphocytic Leukemia Previously Treated with Fixed-Dose Venetoclax Plus Rituximab

Free
Rosemary Anne Harrup, Arnon P. Kater, Barbara F. Eichhorst, Carolyn Owen, Brenda Chyla, Hyun Yong Jin, Yanwen Jiang, Yi Meng Chang, Rosemary Millen, Marcus Lefebure, Maria Thadani-Mulero, Michelle Boyer, John F. Seymour
Journal: Blood
Blood (2023) 142 (Supplement 1): 1898.
https://doi.org/10.1182/blood-2023-177567
Published: 2023
Journal Articles

Endpoint Surrogacy in Chronic Lymphocytic Leukemia: A Pooled Analysis of the German CLL Study Group

Free
Florian Simon, Rudy Ligtvoet, Sandra Robrecht, Paula Cramer, Nadine Kutsch, Moritz Furstenau, Valentin Goede, Julia Von Tresckow, Petra Langerbeins, Anna-Maria Fink, Henriette Huber, Eugen Tausch, Christof Schneider, Clemens-Martin Wendtner, Matthias Ritgen, Martin Dreyling, Lothar Müller, Lutz Jacobasch, Werner Heinz, Ursula Vehling-Kaiser, Liliya Sivcheva, Sebastian Böttcher, Peter Dreger, Thomas Illmer, Michael Gregor, Philipp Bernhard Staber, Stephan Stilgenbauer, Carsten Utoft Niemann, Arnon P. Kater, Kirsten Fischer, Barbara F. Eichhorst, Michael Hallek, Othman Al-Sawaf
Journal: Blood
Blood (2023) 142 (Supplement 1): 1901.
https://doi.org/10.1182/blood-2023-178597
Published: 2023
Journal Articles

Pre-Clinical Study on the Dual BCL2/BCL-XL Inhibitor AZD0466 for the Treatment of Chronic Lymphocytic Leukemia

Free
Billy Jebaraj, Rashmi Priyadharshini Dheenadayalan, Annika Müller, Jialei Qi, Eugen Tausch, Christof Schneider, Daniela Steinbrecher, Daniel Mertens, Felix Seyfried, Lüder Hinrich Meyer, André Lechel, Barbara F. Eichhorst, Courtney L Andersen, Giulia Fabbri, Stephan Stilgenbauer
Journal: Blood
Blood (2023) 142 (Supplement 1): 84.
https://doi.org/10.1182/blood-2023-188554
Published: 2023
Journal Articles

Tislelizumab Plus Zanubrutinib in Patients with Richter Transformation: Primary Endpoint Analysis of the Prospective, Multi-Center, Phase-II RT1 Trial of the German CLL Study Group

Free
Othman Al-Sawaf, Rudy Ligtvoet, Sandra Robrecht, Janina Stumpf, Anna Maria Fink, Eugen Tausch, Christof Schneider, Sebastian Böttcher, Martin Mikusko, Matthias Ritgen, Johannes Schetelig, Julia Von Tresckow, Ursula Vehling-Kaiser, Clemens-Martin Wendtner, Kirsten Fischer, Karl Anton Kreuzer, Stephan Stilgenbauer, Philipp Bernhard Staber, Carsten Utoft Niemann, Michael Hallek, Barbara F. Eichhorst
Journal: Blood
Blood (2023) 142 (Supplement 1): 204.
https://doi.org/10.1182/blood-2023-188705
Published: 2023