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Journal Articles

Laboratories Can Reliably Detect Clinically Relevant Variants in the TP53 Gene below 10 % Allelic Frequency: A Multicenter Study of ERIC, the European Research Initiative on CLL

Sarka Pavlova, Jitka Malcikova, Lenka Radova, Silvia Bonfiglio, Jack B. Cowland, Christian Brieghel, Mette Klarskov Andersen, Maria Karypidou, Bella V Biderman, Michael Doubek, Gregory Lazarian, Inmaculada Rapado, Matthijs Vynck, Naomi Porret, Martin Andres, Dina Rosenberg, Dvora Sahar, Carolina Martinez-Laperche, Ismael Buño Borde, Andrew Hindley, Julio Bravo Sánchez, José García-Marco, Alicia Serrano, Blanca Ferrer Lores, Concepción Fernández-Rodriguez, Beatriz Bellosillo, Stephan Stilgenbauer, Eugen Tausch, Hero Nikdin, Fiona Quinn, Emer Atkinson, Lisette Van De Corput, Cafer Yildiz, Cristina Bilbao, Yanira Florido, Christian Thiede, Caroline Schuster, Anastazja Stoj, Sylwia Czekalska, Anastasia Chatzidimitriou, Stamatia Laidou, Audrey Bidet, Charles Dussiau, Friedel Nollet, Giovanna Piras, Tereza Borosova, Terezia Kurucova, Maria Monne, Svetlana Smirnova, Evgeny Nikitin, Ivan Sloma, Marie-Helene Delfau, Laetitia Largeaud, Loic Ysebaert, Peter J. M. Valk, Amy Christian, Renata Walewska, Marta Sebastião, Maria Gomes da Silva, Piero Galieni, Mario Angelini, Davide Rossi, Valeria Spina, Sónia Matos, Vânia Martins, David Donaldson, Tomasz Stoklosa, Monika Pepek, Panagiotis Baliakas, Rafa Andreu, Irene Luna, Tiina Kahre, Ülle Murumets, Sophie Laird, Daniel Ward, Miguel Alcoceba, Ana Balanzategui, Lydia Scarfo, Francesca Gandini, Ettore Zapparoli, Adoracion Blanco, Pau Abrisqueta Costa, Ana E. Rodriguez, Maria Rocio Benito Sanchez, Frédéric Davi, Clothilde Bravetti, Paula Gameiro, Joaquin Martinez-Lopez, Barbara Tazon, Fanny Baran-Marszak, Zadie Davies, Mark Caterwood, Andrey B Sudarikov, Richard Rosenquist, Carsten Utoft Niemann, Kostas Stamatopoulos, Paolo Ghia, Sarka Pospisilova

Blood (2023) 142 (Supplement 1): 200.

https://doi.org/10.1182/blood-2023-173235

Published: 2023

Journal Articles

ZMYM3 Mutations Cooperate with NOTCH1 Alterations, Reduce Histone H4 Acetylation and Promote Apoptosis Evasion in Chronic Lymphocytic Leukemia

Alberto Rodríguez-Sánchez, Miguel Quijada Álamo, Claudia Perez Carretero, Luis Antonio Corchete Sanchez, Angela Villaverde Ramiro, Cristina Miguel-García, Sandra Santos-Mínguez, Julio Davila Valls, Alfonso Garcia de Coca, Julio Olazabal, Maria Rocio Benito Sanchez, Ana E. Rodriguez, Jesús María Hernández-Rivas

Blood (2023) 142 (Supplement 1): 1886.

https://doi.org/10.1182/blood-2023-188550

Published: 2023

Journal Articles

TRAF3 -Inactivated Chronic Lymphocytic Leukemia Cells Show an Enhanced Metabolic Plasticity That Can be Attenuated By Glutaminolysis and Mitochondrial Pyruvate Import Inhibition

Claudia Perez Carretero, Miguel Quijada Álamo, Mariana Tannoury, Léa Dehgane, Alberto Rodríguez-Sánchez, Teresa González, Maria Rocio Benito Sanchez, Elise Chapiro, Ana E. Rodriguez, Florence Nguyen-Khac, Santos A. Susin, Jesús María Hernández-Rivas

Blood (2023) 142 (Supplement 1): 1889.

https://doi.org/10.1182/blood-2023-187054

Published: 2023

Journal Articles

TRAF3 Alterations Identify a Subgroup of Patients with Adverse Clinical Outcome and Induce Metabolic Reprogramming in Chronic Lymphocytic Leukemia

Claudia Pérez Carretero, Miguel Quijada Álamo, Mariana Tannoury, Léa Dehgane, David J. Sanz, Teresa González, Rocio Benito, Elise Chapiro, Maria Hernandez-Sanchez, Ana E. Rodriguez, Florence Nguyen Khac, Santos A. Susin, Jesús María Hernández-Rivas

Blood (2022) 140 (Supplement 1): 4105–4106.

https://doi.org/10.1182/blood-2022-168861

Published: 2022

Journal Articles

Enabling the Implementation of Next-Generation Sequencing into Clinical Diagnosis: Nemhesys Project

Blood (2022) 140 (Supplement 1): 13122–13124.

https://doi.org/10.1182/blood-2022-163285

Published: 2022

Journal Articles

Different Prognostic Impact of Recurrent Gene Mutations in IGHV-Mutated and IGHV-Unmutated Chronic Lymphocytic Leukemia: A Retrospective, Multi-Center Cohort Study By Eric, the European Research Initiative on CLL, in Harmony

Larry Mansouri, Birna Thorvaldsdottir, Lesley-Ann Sutton, Manja Meggendorfer, Ferran Nadeu, Christian Brieghel, Helen Parker, Stamatia Laidou, Riccardo Moia, Davide Rossi, Mark Catherwood, Jana Kotaskova, Julio Delgado, Ana E Rodríguez-Vicente, Rocio Benito, Gian Matteo Rigolin, Silvia Bonfiglio, Lydia Scarfo, Mattias Mattsson, Zadie Davis, Ajay Gogia, Lata Rani, Panagiotis Baliakas, Cecilia Jylhä, Aron Skaftason, Inmaculada Rapado, Fatima Miras, Joaquin Martinez-Lopez, Javier de la Serna, Jesús M Hernández Rivas, Patrick Thornton, Maria Jose Larrayoz, María José Calasanz, Zoltán Mátrai, Csaba Bodor, Karin E. Smedby, Blanca Espinet, Anna Puiggros, Ritu Gupta, Lars Bullinger, Francesc Bosch, Bárbara Tazón, Fanny Baran-Marszak, David Oscier, Florence Nguyen-Khac, Thorsten Zenz, María José Terol, Antonio Cuneo, María Hernández-Sánchez, Sarka Pospisilova, Ken I Mills, Gianluca Gaidano, Carsten Utoft Niemann, Elías Campo, Jonathan C Strefford, Paolo Ghia, Kostas Stamatopoulos, Richard Rosenquist

Blood (2021) 138 (Supplement 1): 2617.

https://doi.org/10.1182/blood-2021-150648

Published: 2021

Journal Articles

Clinical and Biological Impact of TP53 Alterations in Del(11q) Chronic Lymphocytic Leukemia

Claudia Pérez Carretero, MSc, BSc, Miguel Quijada Álamo, MSc, Maria Hernandez-Sanchez, PhD, Ana E. Rodriguez, PhD, Ana B Herrero, PhD, Jesus M Hernández-Sánchez, PhD, Marta Martín Izquierdo, MSc, Teresa González, PhD, Sandra Santos-Mínguez, Cristina Miguel-García, Araceli Rubio-Martínez, Alfonso García de Coca, MD PhD, Julio Dávila, Jose-Angel Hernandez, MD PhD, Rocio Benito, PhD, José Luis Ordóñez, PhD, Jesus Maria Hernández-Rivas, MD PhD

Blood (2020) 136 (Supplement 1): 6–7.

https://doi.org/10.1182/blood-2020-141015

Published: 2020

Journal Articles

Biological Impact of Monoallelic and Biallelic BIRC3 Loss in Del(11q) Chronic Lymphocytic Leukemia Progression

Miguel Quijada Álamo, MSc, Maria Hernandez-Sanchez, PhD, Ana E. Rodriguez, PhD, Claudia Pérez Carretero, MSc, BSc, Marta Martín Izquierdo, MSc, Verónica Alonso Pérez, PhD, Ignacio García-Tuñón, PhD, Jose Maria Bastida, MDPhD, Maria Jesus Vidal, MD, Josefina Galende DEL Canto, MD, Carlos Aguilar, MD, José Antonio Queizán, MD, Isabel González-Gascón Y Marín, MD PhD, Jose-Angel Hernandez, MD PhD, Rocio Benito, PhD, José Luis Ordóñez, PhD, Jesus Maria Hernández-Rivas, MD PhD

Blood (2020) 136 (Supplement 1): 4.

https://doi.org/10.1182/blood-2020-142658

Published: 2020

Journal Articles

CRISPR/Cas9-Generated Models Uncover Therapeutic Vulnerabilities of Del(11q) Chronic Lymphocytic Leukemia Cells to Dual BCR and PARP Inhibition

Miguel Quijada Álamo, BSc, MSc, María Hernández-Sánchez, PhD, José Luis Ordóñez, PhD, Verónica Alonso Pérez, PhD, Ana E. Rodriguez, PhD, Ignacio García-Tuñón, PhD, Ana B Herrero, PhD, Laura San-Segundo, Michaela Gruber, MD PhD, Juan Luis García, PhD, Rocio Benito, PhD, Catherine J. Wu, MD, Jesús-María Hernández-Rivas, MD PhD

Blood (2018) 132 (Supplement 1): 948.

https://doi.org/10.1182/blood-2018-99-116080

Published: 2018

Journal Articles

Chronic Lymphocytic Leukemia Patients with IGH Rearrangements Are Characterized By a Distinct Genetic Landscape with Prognostic Implications

Blood (2018) 132 (Supplement 1): 3129.

https://doi.org/10.1182/blood-2018-99-115959

Published: 2018

Journal Articles

Analysis of Clonal Evolution in Chronic Lymphocytic Leukemia from Inactive to Symptomatic Disease Prior Treatment Using Whole-Exome Sequencing

María Hernández-Sánchez, Lenka Radova, PhD, Jana Kotaskova, David Tamborero, PhD, Ana E Rodriguez, PhD, Karla Plevova, PhD, María Abáigar, PhD, Vasileios Bikos, Rocío Benito, PhD, Sylvia Takacova, PhD, Miguel Quijada, Ana África Martín, MD, Miguel Alcoceba, BSc, PhD, Alfonso García de Coca, Michael Doubek, Marcos González, MD PhD, Nuria Lopez-Bigas, PhD, Sarka Pospisilova, Jesús María Hernández-Rivas, MD

Blood (2016) 128 (22): 3206.

https://doi.org/10.1182/blood.V128.22.3206.3206

Published: 2016

Journal Articles

Genomic Disruption of the Histone Methyltransferase SETD2 in Chronic Lymphocytic Leukemia

Blood (2015) 126 (23): 365.

https://doi.org/10.1182/blood.V126.23.365.365

Published: 2015

Journal Articles

Analysis of Cytogenetic Abnormalities and Their Prognostic Impact in a Series of 145 Mantle Cell Lymphoma Cases with An Abnormal Karyotype.

Blanca Espinet, PhD, Salaverría Itziar, PhD, Sílvia Beà, PhD, Neus Ruiz-Xivillé, Olga Balagué, MD, Marta Salido, Dolors Costa, PhD, Ana E Rodriguez, Juan LuíS. García, PhD, JesúS. M.ª Hernández-Rivas, MD, PhD, M.ª José Calasanz, PhD, Ana M Ferrer, MD, PhD, Antonio Salar, MD, PhD, Ana Carrió, PhD, Natividad Polo, Jose Antonio García-Marco, MD, PhD, Alicia Domingo, MD, Eva González-Barca, MD, PhD, Vicenç Romagosa, MD, Isabel Marugán, Armando López-Guillermo, MD, PhD, Fuensanta Millá, MD, José Luís Mate, MD, PhD, Elisa Luño, MD, PhD, Carmen Sanzo, MD, PhD, Rosa Collado, MD, PhD, Isabel Oliver, Sebastià Monzó, MD, Antonio Palacín, MD, Teresa González, Francesc Sant, MD, Ramon Salinas, MD, PhD, Mª Teresa Ardanaz, MD, Llorenç Font, MD, PhD, Lourdes Escoda, MD, Lourdes Florensa, MD, PhD, Elias Campo, MD, PhD, Sergi Serrano, MD, PhD, Francesc Solé, PhD

Blood (2008) 112 (11): 1765.

https://doi.org/10.1182/blood.V112.11.1765.1765

Published: 2008

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Laboratories Can Reliably Detect Clinically Relevant Variants in the TP53 Gene below 10 % Allelic Frequency: A Multicenter Study of ERIC, the European Research Initiative on CLL

ZMYM3 Mutations Cooperate with NOTCH1 Alterations, Reduce Histone H4 Acetylation and Promote Apoptosis Evasion in Chronic Lymphocytic Leukemia

TRAF3 -Inactivated Chronic Lymphocytic Leukemia Cells Show an Enhanced Metabolic Plasticity That Can be Attenuated By Glutaminolysis and Mitochondrial Pyruvate Import Inhibition

TRAF3 Alterations Identify a Subgroup of Patients with Adverse Clinical Outcome and Induce Metabolic Reprogramming in Chronic Lymphocytic Leukemia

Enabling the Implementation of Next-Generation Sequencing into Clinical Diagnosis: Nemhesys Project

Different Prognostic Impact of Recurrent Gene Mutations in IGHV-Mutated and IGHV-Unmutated Chronic Lymphocytic Leukemia: A Retrospective, Multi-Center Cohort Study By Eric, the European Research Initiative on CLL, in Harmony

Clinical and Biological Impact of TP53 Alterations in Del(11q) Chronic Lymphocytic Leukemia

Biological Impact of Monoallelic and Biallelic BIRC3 Loss in Del(11q) Chronic Lymphocytic Leukemia Progression

CRISPR/Cas9-Generated Models Uncover Therapeutic Vulnerabilities of Del(11q) Chronic Lymphocytic Leukemia Cells to Dual BCR and PARP Inhibition

Chronic Lymphocytic Leukemia Patients with IGH Rearrangements Are Characterized By a Distinct Genetic Landscape with Prognostic Implications

Analysis of Clonal Evolution in Chronic Lymphocytic Leukemia from Inactive to Symptomatic Disease Prior Treatment Using Whole-Exome Sequencing

Genomic Disruption of the Histone Methyltransferase SETD2 in Chronic Lymphocytic Leukemia

Analysis of Cytogenetic Abnormalities and Their Prognostic Impact in a Series of 145 Mantle Cell Lymphoma Cases with An Abnormal Karyotype.

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