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Amy K Chen
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Journal Articles

Type 2 calreticulin mutations activate ATF6 to promote BCL-xL-mediated survival in myeloproliferative neoplasms

Available to Purchase
Nicole S Arellano, William L Heaton, Mirielle C Nauman, Abigail E Runnels, Jacky Gomez-Villa, Daniele Vanni, Melissa Gaviria, Maihi Fujita, Nathan M Krah, Michele Ciboddo, Saveg Yadav, Callie T Brown, Parker D Bowden, Amy K Chen, Christopher Henning, Silvia Catricalà, Ilaria Carola Casetti, Oscar Borsani, Elisa Rumi, Daniela Pietra, Isabelle Plo, Caroline Marty, Marco Marchetti, Caner Saygin, Ami B Patel, Shannon E Elf
Journal: Blood
Blood blood.2024026940.
https://doi.org/10.1182/blood.2024026940
Published: 2025
Includes: Supplemental data
Journal Articles

Type 2 but Not Type 1 Calreticulin Mutants Exhibit Loss of Chaperone Function Due to C-Terminal Structural Interference, and Bind to Wild Type Calreticulin in a Dominant Negative Manner

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Nicole S Arellano, Jacqueline Gomez, Harrison S Greenbaum, Michele Ciboddo, Deborah Rodriguez, Amy K Chen, Lulu Allie, Alex Rosencrance, Shannon Elf
Journal: Blood
Blood (2022) 140 (Supplement 1): 1087–1088.
https://doi.org/10.1182/blood-2022-166506
Published: 2022