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Alison M. Michie
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Journal Articles

NFATC2 regulates Targets of MYC Signaling in MLL-AF9 AML

Free
Shaun David Patterson, Matthew E Massett, Helen Wheadon, Xu Huang, Heather G Jørgensen, Alison M Michie
Journal: Blood
Blood (2021) 138 (Supplement 1): 3301.
https://doi.org/10.1182/blood-2021-151388
Published: 2021
Journal Articles

Uncoupling p53 from an Embryonic Regulome Exhausts Quiescent CML Stem Cells through Inhibition of a HIF1alpha Molecular Program

Free
Mary T Scott, Wei Liu, Rebecca Mitchell, Cassie Clarke, Hassan Almasoudi, Felix Warren, Ross Kinstrie, Karen Dunn, John Pritchard, Mark E Drotar, Alison M Michie, Heather G Jørgensen, Brian Higgins, Mhairi Copland, David Vetrie
Journal: Blood
Blood (2021) 138 (Supplement 1): 1541.
https://doi.org/10.1182/blood-2021-150372
Published: 2021
Journal Articles

The Histone Demethylase KDM4A Is Required to Sustain H3K9me3/H3K27me3 Epigenetic States and Oncogenesis in MLL-AF9 Acute Myeloid Leukemia

Free
Matthew E Massett, BSc, Niamh Mannion, BSc,PhD, Laura Monaghan, BSc, Joana Bittencourt-Silvestre, BSc, MSc, Sandra Marmiroli, BSc,PhD, Robert M J Liskamp, BSc, PhD, Alison M Michie, BSc, PhD, David Vetrie, BSc, PhD, Xu Huang, BSc, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3879.
https://doi.org/10.1182/blood-2018-99-111256
Published: 2018
Journal Articles

Role of mTORC1 and mTORC2 during Chronic Lymphocytic Leukaemia (CLL) Initiation and Progression

Free
Natasha Malik, BSc, Karen Dunn, Owen Sansom, Prof, Alison M Michie, BSc, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3123.
https://doi.org/10.1182/blood-2018-99-116614
Published: 2018
Journal Articles

Upregulated Cholesterol Biosynthesis Is a Biomarker for Isolated Central Nervous System Relapse in Acute Lymphoblastic Leukaemia

Free
Antony Cousins, Elke Markert, Matilda Degn, PhD, Orianne Olivares, Yasar Mehmood Yousafzai, MBBS,PhD, Saeeda Bhatti, PhD, Pawel Herzyk, Alison M. Michie, PhD BSc, Kjeld Schmiegelow, MD DMSc, Eyal Gottlieb, PhD, Christina Halsey
Journal: Blood
Blood (2017) 130 (Supplement 1): 3992.
https://doi.org/10.1182/blood.V130.Suppl_1.3992.3992
Published: 2017
Journal Articles

CML cells actively evade host immune surveillance through cytokine-mediated downregulation of MHC-II expression

Free
Anuradha Tarafdar, Lisa E. M. Hopcroft, Paolo Gallipoli, Francesca Pellicano, Jennifer Cassels, Alan Hair, Koorosh Korfi, Heather G. Jørgensen, David Vetrie, Tessa L. Holyoake, Alison M. Michie
Journal: Blood
Blood (2017) 129 (2): 199–208.
https://doi.org/10.1182/blood-2016-09-742049
Published: 2017
Includes: Supplemental data
Journal Articles

CXCR2 and CXCL4 regulate survival and self-renewal of hematopoietic stem/progenitor cells

Free
Amy Sinclair, Laura Park, Mansi Shah, Mark Drotar, Simon Calaminus, Lisa E. M. Hopcroft, Ross Kinstrie, Amelie V. Guitart, Karen Dunn, Sheela A. Abraham, Owen Sansom, Alison M. Michie, Laura Machesky, Kamil R. Kranc, Gerard J. Graham, Francesca Pellicano, Tessa L. Holyoake
Journal: Blood
Blood (2016) 128 (3): 371–383.
https://doi.org/10.1182/blood-2015-08-661785
Published: 2016
Includes: Supplemental data
Journal Articles

The ATP-Competitive mTOR Inhibitor AZD8055 Reduces Cell Proliferation and Tumour Load in Chronic Lymphocytic Leukaemia

Free
Emilio Cosimo, Bsc, PhD, Anuradha Tarafdar, PhD, Ailsa Holroyd, MD, Karen Dunn, BSc hons, Mark Catherwood, PhD, Alison M. Michie, PhD BSc
Journal: Blood
Blood (2015) 126 (23): 5287.
https://doi.org/10.1182/blood.V126.23.5287.5287
Published: 2015
Journal Articles

Subversion of Pkca and Pkcbii Upregulation Play an Essential Role in Chronic Lymphocytic Leukaemia Development, Inducing Constitutive B Cell Receptor-Mediated Signals

Free
Anuradha Tarafdar, PhD, Ashfia Fatima Khan, M Pharm, Emilio Cosimo, Bsc, PhD, Hothri A. Moka, BSc hons, Karen Dunn, BSc hons, Alison M. Michie, PhD BSc
Journal: Blood
Blood (2015) 126 (23): 488.
https://doi.org/10.1182/blood.V126.23.488.488
Published: 2015
Journal Articles

Chromatin looping defines expression of TAL1 , its flanking genes, and regulation in T-ALL

Free
Yan Zhou, Sreenivasulu Kurukuti, Peter Saffrey, Milica Vukovic, Alison M. Michie, Ruslan Strogantsev, Adam G. West, David Vetrie
Journal: Blood
Blood (2013) 122 (26): 4199–4209.
https://doi.org/10.1182/blood-2013-02-483875
Published: 2013
Includes: Supplemental data
Journal Articles

Megakaryocytes assemble podosomes that degrade matrix and protrude through basement membrane

Free
Hannah Schachtner, Simon D. J. Calaminus, Amy Sinclair, James Monypenny, Michael P. Blundell, Catherine Leon, Tessa L. Holyoake, Adrian J. Thrasher, Alison M. Michie, Milica Vukovic, Christian Gachet, Gareth E. Jones, Steven G. Thomas, Steve P. Watson, Laura M. Machesky
Journal: Blood
Blood (2013) 121 (13): 2542–2552.
https://doi.org/10.1182/blood-2012-07-443457
Published: 2013
Includes: Multimedia, Supplemental data
Journal Articles

Dasatinib-Induced Apoptosis in Chronic Lymphocytic Leukaemia Is Abrogated by Selective Micro-Environmental Signals.

Free
Alison M McCaig, MBChB, Mike Leach, FRCP, Alison M Michie, PhD
Journal: Blood
Blood (2009) 114 (22): 1264.
https://doi.org/10.1182/blood.V114.22.1264.1264
Published: 2009
Journal Articles

The Signaling Mechanisms That Control Cell Survival Are Differentially-Regulated during the Progression of B-CLL.

Free
Rinako Nakagawa, BSc, MSc, Alison M. Michie, B.Sc, PhD
Journal: Blood
Blood (2005) 106 (11): 1382.
https://doi.org/10.1182/blood.V106.11.1382.1382
Published: 2005