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Volume 88, Issue 3

August 1 1996

Blood Cover Image for Volume 88, Issue 3

In this Issue

REVIEW
ARTICLES
MULTICENTER STUDY
PHOTOGRAPHS
LETTER
ERRATUM

Table of Contents

REVIEW

Molecular analysis of the granulocyte colony-stimulating factor receptor

BR Avalos

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ARTICLES

In vivo adenovirus vector-mediated transfer of the human thrombopoietin cDNA maintains platelet levels during radiation-and chemotherapy- induced bone marrow suppression

A Ohwada,S Rafii,MA Moore,RG Crystal

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TEL-AML1 translocations with TEL and CDKN2 inactivation in acute lymphoblastic leukemia cell lines

DH Kim,RL Moldwin,C Vignon,SK Bohlander,Y Suto,L Giordano,R Gupta,S Fears,G Nucifora,JD Rowley

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Low levels of erythroid and myeloid progenitors in thrombopoietin-and c- mpl-deficient mice

K Carver-Moore,HE Broxmeyer,SM Luoh,S Cooper,J Peng,SA Burstein,MW Moore,FJ de Sauvage

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Constitutive activation of STAT proteins in primary lymphoid and myeloid leukemia cells and in Epstein-Barr virus (EBV)-related lymphoma cell lines

RM Weber-Nordt,C Egen,J Wehinger,W Ludwig,V Gouilleux-Gruart,R Mertelsmann,J Finke

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Monocyte function in a severe combined immunodeficient patient with a donor splice site mutation in the Jak3 gene

A Villa,M Sironi,P Macchi,C Matteucci,LD Notarangelo,P Vezzoni,A Mantovani

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Evaluation of a CD5-specific immunotoxin for treatment of acute graft- versus-host disease after allogeneic marrow transplantation

PJ Martin,BJ Nelson,FR Appelbaum,C Anasetti,HJ Deeg,JA Hansen,GB McDonald,RA Nash,KM Sullivan,RP Witherspoon,PJ Scannon,N Friedmann,R Storb

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Effectiveness of intensified rotational combination chemotherapy for late hematologic relapse of childhood acute lymphoblastic leukemia

GK Rivera,MM Hudson,Q Liu,E Benaim,RC Ribeiro,WM Crist,CH Pui

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Autotransplants in multiple myeloma: what have we learned?

DH Vesole,G Tricot,S Jagannath,KR Desikan,D Siegel,D Bracy,L Miller,B Cheson,J Crowley,B Barlogie

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Mechanism of transcriptional activation of the immediate early gene Egr- 1 in response to PIXY321

RC Mignacca,HJ Lee,EM Kwon,KM Sakamoto

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Fibronectin improves transduction of reconstituting hematopoietic stem cells by retroviral vectors: evidence of direct viral binding to chymotryptic carboxy-terminal fragments

T Moritz,P Dutt,X Xiao,D Carstanjen,T Vik,H Hanenberg,DA Williams

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Direct synergistic effects of leukemia inhibitory factor on hematopoietic progenitor cell growth: comparison with other hematopoietins that use the gp130 receptor subunit

JR Keller,JM Gooya,FW Ruscetti

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Restoration of thrombolytic potential in plasminogen-deficient mice by bolus administration of plasminogen

HR Lijnen,P Carmeliet,A Bouche,L Moons,VA Ploplis,EF Plow,D Collen

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Venous thromboembolism associated with double heterozygosity for R506Q mutation of factor V and for T298M mutation of protein C in a large family of a previously described homozygous protein C-deficient newborn with massive thrombosis

B Brenner,A Zivelin,N Lanir,JS Greengard,JH Griffin,U Seligsohn

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Factor VIIa and antithrombin III activity during severe sepsis and septic shock in neutropenic patients

RM Mesters,PM Mannucci,R Coppola,T Keller,H Ostermann,J Kienast

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Distribution of ligand-occupied alpha IIb beta 3 in resting and activated human platelets determined by expression of a novel class of ligand-induced binding site recognized by monoclonal antibody AP6

P Nurden,M Humbert,RS Piotrowicz,C Bihour,C Poujol,AT Nurden,TJ Kunicki

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Evolution of blood coagulation activators and inhibitors in the healthy human fetus

P Reverdiau-Moalic,B Delahousse,G Body,P Bardos,J Leroy,Y Gruel

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Analysis of GPIIb/IIIa receptor number by quantification of 7E3 binding to human platelets

CL Wagner,MA Mascelli,DS Neblock,HF Weisman,BS Coller,RE Jordan

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Molecular characterization of a glycosylphosphatidylinositol-linked ADP- ribosyltransferase from lymphocytes

IJ Okazaki,HJ Kim,NG McElvaney,E Lesma,J Moss

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Tumor necrosis factor-alpha induces activation of coagulation and fibrinolysis in baboons through an exclusive effect on the p55 receptor

T van der Poll,PM Jansen,KJ Van Zee,MB 3rd Welborn,I de Jong,CE Hack,H Loetscher,W Lesslauer,SF Lowry,LL Moldawer

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Cystamine inhibits human immunodeficiency virus-1 replication in cord blood-derived mononuclear phagocytes and lymphocytes

WZ Ho,D Kaufman,L Song,JR Cutillii,SD Douglas

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Recirculation and homing of lymphocyte subsets: dual homing specificity of beta 7-integrin(high)-lymphocytes in nonobese diabetic mice

A Hanninen,M Salmi,O Simell,D Andrew,S Jalkanen

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Decreased interleukin-12 (IL-12) from activated cord versus adult peripheral blood mononuclear cells and upregulation of interferon- gamma, natural killer, and lymphokine-activated killer activity by IL- 12 in cord blood mononuclear cells

SM Lee,Y Suen,L Chang,V Bruner,J Qian,J Indes,E Knoppel,C van de Ven,MS Cairo

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Tumor vaccination with macrophage colony-stimulating factor-producing Lewis lung carcinoma in mice

T Morita,K Ikeda,M Douzono,M Yamada,F Kimura,K Kawakami,K Sasaki,K Motoyoshi,J Takahara,S Irino

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Prevention of allogeneic marrow graft rejection by donor T cells that do not recognize recipient alloantigens: potential role of a veto mechanism

PJ Martin

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Modulated expression of notch1 during thymocyte development

RP Hasserjian,JC Aster,F Davi,DS Weinberg,J Sklar

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Detection and quantification of melphalan-DNA adducts at the single cell level in hematopoietic tumor cells

AJ Frank,SJ Proctor,MJ Tilby

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Application of long-distance polymerase chain reaction to detection of junctional sequences created by chromosomal translocation in mature B- cell neoplasms

T Akasaka,M Muramatsu,H Ohno,I Miura,E Tatsumi,S Fukuhara,T Mori,M Okuma

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Neoplastic transformation of normal hematopoietic cells by constitutively activating mutations of c-kit receptor tyrosine kinase

H Kitayama,T Tsujimura,I Matsumura,K Oritani,H Ikeda,J Ishikawa,M Okabe,M Suzuki,K Yamamura,Y Matsuzawa,Y Kitamura,Y Kanakura

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Antisense oligodeoxynucleotide combination therapy of primary chronic myelogenous leukemia blast crisis in SCID mice

T Skorski,M Nieborowska-Skorska,P Wlodarski,G Zon,RV Iozzo,B Calabretta

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Prognostic factors in agnogenic myeloid metaplasia: a report on 195 cases with a new scoring system [see comments]

B Dupriez,P Morel,JL Demory,JL Lai,M Simon,I Plantier,F Bauters

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The effect of the Fanconi anemia polypeptide, FAC, upon p53 induction and G2 checkpoint regulation

GM Kupfer,AD D'Andrea

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Frequent clonal loss of heterozygosity but scarcity of microsatellite instability at chromosomal breakpoint cluster regions in adult leukemias

T Pabst,J Schwaller,MJ Bellomo,M Oestreicher,D Muhlematter,A Tichelli,A Tobler,MF Fey

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Interleukin-10 gene expression in adult T-cell leukemia

N Mori,PS Gill,T Mougdil,S Murakami,S Eto,D Prager

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Prognostic significance of BCL-2 expression and bcl-2 major breakpoint region rearrangement in diffuse large cell non-Hodgkin's lymphoma: a British National Lymphoma Investigation Study

ME Hill,KA MacLennan,DC Cunningham,B Vaughan Hudson,M Burke,P Clarke,F Di Stefano,L Anderson,G Vaughan Hudson,D Mason,P Selby,DC Linch

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In vitro studies on cellular and molecular mechanisms of arsenic trioxide (As2O3) in the treatment of acute promyelocytic leukemia: As2O3 induces NB4 cell apoptosis with downregulation of Bcl-2 expression and modulation of PML-RAR alpha/PML proteins

GQ Chen,J Zhu,XG Shi,JH Ni,HJ Zhong,GY Si,XL Jin,W Tang,XS Li,SM Xong,ZX Shen,GL Sun,J Ma,P Zhang,TD Zhang,C Gazin,T Naoe,SJ Chen,ZY Wang,Z Chen

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Hereditary spherocytosis with band 3 deficiency. Association with a nonsense mutation of the band 3 gene (allele Lyon), and aggravation by a low-expression allele occurring in trans (allele Genas)

N Alloisio,P Maillet,G Carre,P Texier,A Vallier,F Baklouti,N Philippe,J Delaunay

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Inhibition of hemoglobin expression by heterologous production of nitric oxide synthase in the K562 erythroleukemic cell line

SP Rafferty,JB Domachowske,HL Malech

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In vivo search for butyrate responsive sequences using transgenic mice carrying A gamma gene promoter mutants

BS Pace,Q Li,G Stamatoyannopoulos

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Active involvement of catalase during hemolytic crises of favism

GF Gaetani,M Rolfo,S Arena,R Mangerini,GF Meloni,AM Ferraris

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Reconstruction of the immune system after unrelated or partially matched T-cell-depleted bone marrow transplantation in children: immunophenotypic analysis and factors affecting the speed of recovery

H Kook,F Goldman,D Padley,R Giller,S Rumelhart,M Holida,N Lee,C Peters,M Comito,D Huling,M Trigg

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Human HLA-specific T-cell clones with stable expression of a suicide gene: a possible tool to drive and control a graft-versus-host- graft- versus-leukemia reaction?

G Gallot,MM Hallet,J Gaschet,JF Moreau,R Vivien,M Bonneville,N Milpied,H Vie

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Granulocyte colony-stimulating factor recruitment of CD34+ progenitors to peripheral blood: impaired mobilization in chronic granulomatous disease and adenosine deaminase--deficient severe combined immunodeficiency disease patients

S Sekhsaria,TA Fleisher,S Vowells,M Brown,J Miller,I Gordon,RM Blaese,CE Dunbar,S Leitman,HL Malech

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Interferon-gamma suppresses T-cell proliferation to mitogen via the nitric oxide pathway during experimental acute graft-versus-host disease

W Krenger,G Falzarano,J Jr Delmonte,KM Snyder,JC Byon,JL Ferrara

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MULTICENTER STUDY

Successful transplantation of HLA-matched and HLA-mismatched umbilical cord blood from unrelated donors: analysis of engraftment and acute graft-versus-host disease

JE Wagner,J Rosenthal,R Sweetman,XO Shu,SM Davies,NK Ramsay,PB McGlave,L Sender,MS Cairo

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PHOTOGRAPHS

Acute myeloid leukemia, M2 with t8:21 translocation

PT Murphy,G Fahy,C Harworth

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LETTER

Monoclonal gammopathy in patients with chronic hepatitis C virus infection [letter]

P Andreone,A Gramenzi,C Cursaro,M Bernardi,AL Zignego

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Fas (CD95) receptor and Fas-ligand expression in bone marrow cells from patients with myelodysplastic syndrome [letter]

GM Gersuk,JW Lee,CA Beckham,J Anderson,HJ Deeg

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Growth of Epstein-Barr virus-associated B-lymphoproliferative disease tissue in a severe combined immunodeficient mouse [letter]

SM Perera,I Johannessen,JA Thomas,LA Brooks,JN Jobe,DH Crawford,R Radley- Smith,M Phillips

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Circulating clonal lymphocytes in myeloma determined by mRNA in situ hybridization [letter; comment]

DE Joshua,RD Brown,XF Luo,J Gibson

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Risk of hepatitis C virus infection, Waldenstrom's macroglobulinemia, and monoclonal gammopathies [letter; comment]

F Silvestri,G Barillari,R Fanin,F Zaja,L Infanti,F Patriarca,M Baccarani,C Pipan,E Falasca,GA Botta

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ERRATUM

Erratum

J. G. White

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Erratum for vol. 87, p. 630

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RETRACTION

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Erratum for vol. 86, p. 2774

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