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Volume 87, Issue 8

April 15 1996

In this Issue

PHOTOGRAPHS
REVIEW
ARTICLES
MULTICENTER STUDY
LETTER

PHOTOGRAPHS

Photograph

J. M. Mariz,M. Marques,I. Barbosa,F. Viseu

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REVIEW

Treatment of chronic myelogenous leukemia: current status and investigational options [see comments]

HM Kantarjian,S O'Brien,P Anderlini,M Talpaz

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Ex vivo expansion of hematopoietic precursors, progenitors, and stem cells: the next generation of cellular therapeutics

SG Emerson

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ARTICLES

Cloning of human Bcl-2 homologue: inflammatory cytokines induce human A1 in cultured endothelial cells

A Karsan,E Yee,K Kaushansky,JM Harlan

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Retroviral-mediated gene correction for X-linked severe combined immunodeficiency

F Candotti,JA Johnston,JM Puck,K Sugamura,JJ O'Shea,RM Blaese

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Correction of interleukin-2 receptor function in X-SCID lymphoblastoid cells by retrovirally mediated transfer of the gamma-c gene

N Taylor,L Uribe,S Smith,T Jahn,DB Kohn,K Weinberg

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gamma-c gene transfer into SCID X1 patients' B-cell lines restores normal high-affinity interleukin-2 receptor expression and function

H Hacein-Bey,M Cavazzana-Calvo,F Le Deist,A Dautry-Varsat,C Hivroz,I Riviere,O Danos,JM Heard,K Sugamura,A Fischer,G De Saint Basile

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A point mutation in the catalytic domain of c-kit induces growth factor independence, tumorigenicity, and differentiation of mast cells

X Piao,A Bernstein

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Molecular cloning of complex chromosomal translocation t(8;14;12)(q24.1;q32.3;q24.1) in a Burkitt lymphoma cell line defines a new gene (BCL7A) with homology to caldesmon

VJ Zani,N Asou,D Jadayel,JM Heward,J Shipley,E Nacheva,K Takasuki,D Catovsky,MJ Dyer

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A randomized phase-III study of the efficacy of granulocyte colony- stimulating factor in children with high-risk acute lymphoblastic leukemia. Berlin-Frankfurt-Munster Study Group

K Welte,A Reiter,K Mempel,M Pfetsch,G Schwab,M Schrappe,H Riehm

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Murine JAK3 is preferentially expressed in hematopoietic tissues and lymphocyte precursor cells

CB Gurniak,LJ Berg

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Hematopoietic progenitors and interleukin-3-dependent cell lines synthesize histamine in response to calcium ionophore

M Dy,A Arnould,FM Lemoine,F Machavoine,H Ziltener,E Schneider

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Involvement of peripheral benzodiazepine receptors in the protection of hematopoietic cells against oxygen radical damage

P Carayon,M Portier,D Dussossoy,A Bord,G Petitpretre,X Canat,G Le Fur,P Casellas

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Aplastic anemia: evidence for dysfunctional bone marrow progenitor cells and the corrective effect of granulocyte colony-stimulating factor in vitro

J Scopes,S Daly,R Atkinson,SE Ball,EC Gordon-Smith,FM Gibson

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Genetic basis of hypo-responsiveness of A/J mice to interleukin-3

KB Leslie,S Jalbert,P Orban,M Welham,V Duronio,JW Schrader

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Stem cell factor enhances interleukin-3 dependent induction of 68-kD calmodulin-binding protein and thymidine kinase activity in NFS-60 cells

GP Reddy,PJ Quesenberry

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Xenogeneic expression of human stem cell factor in transgenic mice mimics codominant c-kit mutations

MK Majumdar,ET Everett,X Xiao,R Cooper,K Langley,R Kapur,T Vik,DA Williams

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Effect of recombinant erythropoietin in interaction with stromal factors on cord blood hematopoiesis

T Abe,Y Takaue,Y Kawano,Y Kuroda

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A novel hematopoietic multilineage clone, Myl-D-7, is stromal cell- dependent and supported by an alternative mechanism(s) independent of stem cell factor/c-kit interaction

K Itoh,J Friel,N Kluge,T Kina,A Kondo-Takaori,S Kawamata,T Uchiyama,W Ostertag

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Stromal fibroblast heparan sulfate is required for cytokine-mediated ex vivo maintenance of human long-term culture-initiating cells

P Gupta,JB McCarthy,CM Verfaillie

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Engraftment potential of different sources of human hematopoietic progenitor cells in BNX Mice

CW Turner,AM Yeager,EK Waller,JR Wingard,WH Fleming

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Plasma from patients with idiopathic and human immunodeficiency virus- associated thrombotic thrombocytopenic purpura induces apoptosis in microvascular endothelial cells

J Laurence,D Mitra,M Steiner,L Staiano-Coico,E Jaffe

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A novel DNA inversion causing severe hemophilia A

JA Naylor,P Nicholson,Anne Goodeve,S Hassock,I Peake,F Giannelli

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Human beta2-glycoprotein I as an anticardiolipin cofactor determined using mutants expressed by a baculovirus system

M Igarashi,E Matsuura,Y Igarashi,H Nagae,K Ichikawa,DA Triplett,T Koike

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Platelet-dependent primary hemostasis promotes selectin- and integrin- mediated neutrophil adhesion to damaged endothelium under flow conditions

PH Kuijper,HI Gallardo Torres,JA van der Linden,JW Lammers,JJ Sixma,L Koenderman,JJ Zwaginga

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Increased soluble interleukin-1 type II receptor concentrations in postoperative patients and in patients with sepsis syndrome

JH Pruitt,MB Welborn,PD Edwards,TR Harward,JW Seeger,TD Martin,C Smith,JA Kenney,RI Wesdorp,S Meijer,MA Cuesta,A Abouhanze,EM 3rd Copeland,J Giri,JE Sims,LL Moldawer,HS Oldenburg

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Autoantibodies inhibit interleukin-7-mediated proliferation and are associated with the age-dependent loss of pre-B cells in autoimmune New Zealand Black Mice

MS Merchant,BA Garvy,RL Riley

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Clonal populations of CD4+ and CD8+ T cells in patients with multiple myeloma and paraproteinemia

P Moss,G Gillespie,P Frodsham,J Bell,H Reyburn

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Interleukin-13 (IL-13) induces IL-1 receptor antagonist gene expression and protein synthesis in peripheral blood mononuclear cells: inhibition by an IL-4 mutant protein

E Vannier,R de Waal Malefyt,A Salazar-Montes,JE de Vries,CA Dinarello

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Coexpression of the interleukin-13 and interleukin-4 genes correlates with their physical linkage in the cytokine gene cluster on human chromosome 5q23-31

G Dolganov,S Bort,M Lovett,J Burr,L Schubert,D Short,M McGurn,C Gibson,DB Lewis

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Interleukin-15 promotes the growth of leukemic cells of patients with B- cell chronic lymphoproliferative disorders

L Trentin,A Cerutti,R Zambello,R Sancretta,C Tassinari,M Facco,F Adami,F Rodeghiero,C Agostini,G Semenzato

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Migration of human monocytes in response to vascular endothelial growth factor (VEGF) is mediated via the VEGF receptor flt-1

B Barleon,S Sozzani,D Zhou,HA Weich,A Mantovani,D Marme

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Expression of the interleukin-2 receptor gamma chain on cord blood mononuclear cells

S Saito,T Morii,H Umekage,K Makita,K Nishikawa,N Narita,M Ichijo,H Morikawa,N Ishii,M Nakamura,K Sugamura

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p53 gene mutations and protein overexpression are associated with aggressive variants of mantle cell lymphomas

L Hernandez,T Fest,M Cazorla,J Teruya-Feldstein,F Bosch,MA Peinado,MA Piris,E Montserrat,A Cardesa,ES Jaffe,E Campo,M Raffold

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Cyclin E overexpression in relapsed adult acute lymphoblastic leukemias of B-cell lineage

R Scuderi,KA Palucka,K Pokrovskaja,M Bjorkholm,KG Wiman,P Pisa

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Acute lymphoblastic leukemia of childhood: identification of two distinct regions of deletion on the short arm of chromosome 12 in the region of TEL and KIP1

S Takeuchi,CR Bartram,CW Miller,A Reiter,T Seriu,M Zimmerann,M Schrappe,N Mori,J Slater,I Miyoshi,HP Koeffler

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Plasma cells induce apoptosis of pre-B cells by interacting with bone marrow stromal cells

T Tsujimoto,IA Lisukov,N Huang,MS Mahmoud,MM Kawano

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Enhancement of activity of 1alpha, 25-dihydroxyvitamin D3 for growth inhibition and differentiation induction of human myelomonocytic leukemia cells by tretinoin tocoferil, an alpha-tocopherol ester of all- trans retinoic acid

M Makishima,Y Kanatani,Y Yamamoto-Yamaguchi,Y Honma

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Enhanced metabolism of 1-beta-D-arabinofuranosylcytosine in Down syndrome cells: a contributing factor to the superior event free survival of Down syndrome children with acute myeloid leukemia

JW Taub,LH Matherly,ML Stout,SA Buck,JG Gurney,Y Ravindranath

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Establishment of a human acute promyelocytic leukemia-ascites model in SCID mice

SY Zhang,J Zhu,GQ Chen,XX Du,LJ Lu,Z Zhang,HJ Zhong,HR Chen,ZY Wang,R Berger,M Lanotte,S Waxman,Z Chen,SJ Chen

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Transactivation of the interleukin-1alpha promoter by human T-cell leukemia virus type I and type II Tax proteins

N Mori,D Prager

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Peripheral blood mononuclear cells of a patient with advanced Hodgkin's lymphoma give rise to permanently growing Hodgkin-Reed Sternberg cells

J Wolf,U Kapp,H Bohlen,M Kornacker,C Schoch,B Stahl,S Mucke,C von Kalle,C Fonatsch,HE Schaefer,ML Hansmann,V Diehl

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Molecular single cell analysis demonstrates the derivation of a peripheral blood-derived cell line (L1236) from the Hodgkin/Reed- Sternberg cells of a Hodgkin's lymphoma patient

H Kanzler,ML Hansmann,U Kapp,J Wolf,V Diehl,K Rajewsky,R Kuppers

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The t(2;5) chromosomal translocation is not a common feature of primary cutaneous CD30+ lymphoproliferative disorders: comparison with anaplastic large-cell lymphoma of nodal origin [see comments]

JF DeCoteau,JR Butmarc,MC Kinney,ME Kadin

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The diadenosine polyphosphates Ap3A and Ap4A and adenosine triphosphate interact with granulocyte-macrophage colony-stimulating factor to delay neutrophil apoptosis: implications for neutrophil: platelet interactions during inflammation

L Gasmi,AG McLennan,SW Edwards

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Neutrophil deactivation by influenza A viruses: mechanisms of protection after viral opsonization with collectins and hemagglutination-inhibiting antibodies

KL Hartshorn,KB Reid,MR White,JC Jensenius,SM Morris,AI Tauber,E Crouch

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Reduced invasion and growth of Plasmodium falciparum into elliptocytic red blood cells with a combined deficiency of protein 4.1, glycophorin C, and p55

AH Chishti,J Palek,D Fisher,GJ Maalouf,SC Liu

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Associations of iron overload in Africa with hepatocellular carcinoma and tuberculosis: Strachan's 1929 thesis revisited

VR Gordeuk,CE McLaren,AP MacPhail,G Deichsel,TH Bothwell

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Distribution of iron in reticulocytes after inhibition of heme synthesis with succinylacetone: examination of the intermediates involved in iron metabolism

DR Richardson,P Ponka,D Vyoral

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Cholesterol-loading of membranes of normal erythrocytes inhibits phospholipid repair and arachidonoyl-CoA:1-palmitoyl-sn-glycero-3- phosphocholine acyl transferase. A model of spur cell anemia

DW Allen,N Manning

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Persistence of mixed chimerism in patients transplanted for the treatment of thalassemia

M Andreani,M Manna,G Lucarelli,P Tonucci,F Agostinelli,M Ripalti,S Rapa,N Talevi,M Galimberti,S Nesci

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The repopulation potential of fetal liver hematopoietic stem cells in mice exceeds that of their liver adult bone marrow counterparts

VI Rebel,CL Miller,CJ Eaves,PM Lansdorp

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Allogenic transplant of canine peripheral blood stem cells mobilized by recombinant canine hematopoietic growth factors

BM Sandmaier,R Storb,EB Santos,L Krizanac-Bengez,T Lian,PA McSweeney,C Yu,FG Schuening,HJ Deeg,T Graham

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MULTICENTER STUDY

Cytogenetic abnormalities in adult acute lymphoblastic leukemia: correlations with hematologic findings outcome. A Collaborative Study of the Group Francais de Cytogenetique Hematologique [published erratum appears in Blood 1996 Oct 1;88(7):2818]

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FK506 (Tacrolimus) monotherapy for prevention of graft-versus-host disease after histocompatible sibling allogenic bone marrow transplantation

JW Fay,JR Wingard,JH Antin,RH Collins,LA Pineiro,BR Blazar,R Saral,BE Bierer,D Przepiorka,WE Fitzsimmons,RM Maher,DJ Weisdorf

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LETTER

Similarities between T-cell chronic lymphocytic leukemia and the small- cell variant of T-prolymphocytic leukemia [letter; comment]

E Matutes,D Catovsky

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Human immunodeficiency virus-1 infection, homosexuality, and Kaposi- associated herpes-like DNA in peripheral blood mononuclear cells [letter]

A De Milito,M Catucci,G Venturi,L Romano,PE Valensin,M Zazzi,P Almi

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Lymphocyte transfusion therapy for cancer patients [letter]

PD Boasberg,KM Tokita,PI Terasaki,X Wang

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Pure red blood cell aplasia associated with parvovirus B19 infection in large granular lymphocyte leukemia [letter]

D Ergas,P Resnitzky,A Berrebi

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Potentiation of neutrophil functions with administration of granulocyte colony-stimulating factor to donors for granulocyte transfusions [letter; comment]

M Katoh,M Takada,M Nakayama,M Umeda

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Possible misdiagnosis of factor VIII gene inversion in a case of severe hemophilia A [letter]

B Benichou,O Herbert,S Huet,MT Andre,S Bezieau,MG Le Roux,M Fiks-Siguad,JP Moisan

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2-Chlorodeoxyadenosine as first-line treatment in bronchus-associated lymphoid tissue lymphoma [letter]

P Neumeister,W Linkesch,G Hofler,H Sill

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Predictive value of the steady-state peripheral blood progenitor cell (PBPC) counts for the yield of PBPC collected by leukapheresis after mobilization by granulocyte colony-stimulating factor (G-CSF) alone or chemotherapy and G-CSF [letter; comment]

B Husson,C Ravoet,M Dehon,G Wallef,N Hougardy,A Delannoy

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Table of Contents

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Layilin inhibits integrin activation, and its loss results in platelet hyperactivation via Rac1 in inflammatory bowel disease

A T-cell-based metric of immune age predicts outcomes in older patients with myeloma receiving daratumumab-based therapy

A phase 2 study of zanubrutinib in combination with rituximab and lenalidomide in de novo diffuse large B-cell lymphoma

Proteomic subtypes enrich current acute myeloid leukemia nomenclature and reflect intrinsic pathogenesis alongside aging

Epigenetic changes by EZH2 inhibition increase translocations in B cells with high AID activity or DNA repair deficiency

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Issue Archive

Table of Contents

PHOTOGRAPHS

Photograph Free

REVIEW

Treatment of chronic myelogenous leukemia: current status and investigational options [see comments] Free

Ex vivo expansion of hematopoietic precursors, progenitors, and stem cells: the next generation of cellular therapeutics Free

ARTICLES

Cloning of human Bcl-2 homologue: inflammatory cytokines induce human A1 in cultured endothelial cells Free

Retroviral-mediated gene correction for X-linked severe combined immunodeficiency Free

Correction of interleukin-2 receptor function in X-SCID lymphoblastoid cells by retrovirally mediated transfer of the gamma-c gene Free

gamma-c gene transfer into SCID X1 patients' B-cell lines restores normal high-affinity interleukin-2 receptor expression and function Free

A point mutation in the catalytic domain of c-kit induces growth factor independence, tumorigenicity, and differentiation of mast cells Free

Molecular cloning of complex chromosomal translocation t(8;14;12)(q24.1;q32.3;q24.1) in a Burkitt lymphoma cell line defines a new gene (BCL7A) with homology to caldesmon Free

A randomized phase-III study of the efficacy of granulocyte colony- stimulating factor in children with high-risk acute lymphoblastic leukemia. Berlin-Frankfurt-Munster Study Group Free

Murine JAK3 is preferentially expressed in hematopoietic tissues and lymphocyte precursor cells Free

Hematopoietic progenitors and interleukin-3-dependent cell lines synthesize histamine in response to calcium ionophore Free

Involvement of peripheral benzodiazepine receptors in the protection of hematopoietic cells against oxygen radical damage Free

Aplastic anemia: evidence for dysfunctional bone marrow progenitor cells and the corrective effect of granulocyte colony-stimulating factor in vitro Free

Genetic basis of hypo-responsiveness of A/J mice to interleukin-3 Free

Stem cell factor enhances interleukin-3 dependent induction of 68-kD calmodulin-binding protein and thymidine kinase activity in NFS-60 cells Free

Xenogeneic expression of human stem cell factor in transgenic mice mimics codominant c-kit mutations Free

Effect of recombinant erythropoietin in interaction with stromal factors on cord blood hematopoiesis Free

A novel hematopoietic multilineage clone, Myl-D-7, is stromal cell- dependent and supported by an alternative mechanism(s) independent of stem cell factor/c-kit interaction Free

Stromal fibroblast heparan sulfate is required for cytokine-mediated ex vivo maintenance of human long-term culture-initiating cells Free

Engraftment potential of different sources of human hematopoietic progenitor cells in BNX Mice Free

Plasma from patients with idiopathic and human immunodeficiency virus- associated thrombotic thrombocytopenic purpura induces apoptosis in microvascular endothelial cells Free

A novel DNA inversion causing severe hemophilia A Free

Human beta2-glycoprotein I as an anticardiolipin cofactor determined using mutants expressed by a baculovirus system Free

Platelet-dependent primary hemostasis promotes selectin- and integrin- mediated neutrophil adhesion to damaged endothelium under flow conditions Free

Increased soluble interleukin-1 type II receptor concentrations in postoperative patients and in patients with sepsis syndrome Free

Autoantibodies inhibit interleukin-7-mediated proliferation and are associated with the age-dependent loss of pre-B cells in autoimmune New Zealand Black Mice Free

Clonal populations of CD4+ and CD8+ T cells in patients with multiple myeloma and paraproteinemia Free

Interleukin-13 (IL-13) induces IL-1 receptor antagonist gene expression and protein synthesis in peripheral blood mononuclear cells: inhibition by an IL-4 mutant protein Free

Coexpression of the interleukin-13 and interleukin-4 genes correlates with their physical linkage in the cytokine gene cluster on human chromosome 5q23-31 Free

Interleukin-15 promotes the growth of leukemic cells of patients with B- cell chronic lymphoproliferative disorders Free

Migration of human monocytes in response to vascular endothelial growth factor (VEGF) is mediated via the VEGF receptor flt-1 Free

Expression of the interleukin-2 receptor gamma chain on cord blood mononuclear cells Free

p53 gene mutations and protein overexpression are associated with aggressive variants of mantle cell lymphomas Free

Cyclin E overexpression in relapsed adult acute lymphoblastic leukemias of B-cell lineage Free

Acute lymphoblastic leukemia of childhood: identification of two distinct regions of deletion on the short arm of chromosome 12 in the region of TEL and KIP1 Free

Plasma cells induce apoptosis of pre-B cells by interacting with bone marrow stromal cells Free

Enhancement of activity of 1alpha, 25-dihydroxyvitamin D3 for growth inhibition and differentiation induction of human myelomonocytic leukemia cells by tretinoin tocoferil, an alpha-tocopherol ester of all- trans retinoic acid Free

Enhanced metabolism of 1-beta-D-arabinofuranosylcytosine in Down syndrome cells: a contributing factor to the superior event free survival of Down syndrome children with acute myeloid leukemia Free

Establishment of a human acute promyelocytic leukemia-ascites model in SCID mice Free

Transactivation of the interleukin-1alpha promoter by human T-cell leukemia virus type I and type II Tax proteins Free

Peripheral blood mononuclear cells of a patient with advanced Hodgkin's lymphoma give rise to permanently growing Hodgkin-Reed Sternberg cells Free

Molecular single cell analysis demonstrates the derivation of a peripheral blood-derived cell line (L1236) from the Hodgkin/Reed- Sternberg cells of a Hodgkin's lymphoma patient Free

The t(2;5) chromosomal translocation is not a common feature of primary cutaneous CD30+ lymphoproliferative disorders: comparison with anaplastic large-cell lymphoma of nodal origin [see comments] Free

The diadenosine polyphosphates Ap3A and Ap4A and adenosine triphosphate interact with granulocyte-macrophage colony-stimulating factor to delay neutrophil apoptosis: implications for neutrophil: platelet interactions during inflammation Free

Neutrophil deactivation by influenza A viruses: mechanisms of protection after viral opsonization with collectins and hemagglutination-inhibiting antibodies Free

Reduced invasion and growth of Plasmodium falciparum into elliptocytic red blood cells with a combined deficiency of protein 4.1, glycophorin C, and p55 Free

Associations of iron overload in Africa with hepatocellular carcinoma and tuberculosis: Strachan's 1929 thesis revisited Free

Distribution of iron in reticulocytes after inhibition of heme synthesis with succinylacetone: examination of the intermediates involved in iron metabolism Free

Cholesterol-loading of membranes of normal erythrocytes inhibits phospholipid repair and arachidonoyl-CoA:1-palmitoyl-sn-glycero-3- phosphocholine acyl transferase. A model of spur cell anemia Free

Persistence of mixed chimerism in patients transplanted for the treatment of thalassemia Free

The repopulation potential of fetal liver hematopoietic stem cells in mice exceeds that of their liver adult bone marrow counterparts Free

Allogenic transplant of canine peripheral blood stem cells mobilized by recombinant canine hematopoietic growth factors Free

MULTICENTER STUDY

Cytogenetic abnormalities in adult acute lymphoblastic leukemia: correlations with hematologic findings outcome. A Collaborative Study of the Group Francais de Cytogenetique Hematologique [published erratum appears in Blood 1996 Oct 1;88(7):2818] Free

FK506 (Tacrolimus) monotherapy for prevention of graft-versus-host disease after histocompatible sibling allogenic bone marrow transplantation Free

LETTER

Similarities between T-cell chronic lymphocytic leukemia and the small- cell variant of T-prolymphocytic leukemia [letter; comment] Free

Human immunodeficiency virus-1 infection, homosexuality, and Kaposi- associated herpes-like DNA in peripheral blood mononuclear cells [letter] Free

Lymphocyte transfusion therapy for cancer patients [letter] Free

Pure red blood cell aplasia associated with parvovirus B19 infection in large granular lymphocyte leukemia [letter] Free

Potentiation of neutrophil functions with administration of granulocyte colony-stimulating factor to donors for granulocyte transfusions [letter; comment] Free

Possible misdiagnosis of factor VIII gene inversion in a case of severe hemophilia A [letter] Free

2-Chlorodeoxyadenosine as first-line treatment in bronchus-associated lymphoid tissue lymphoma [letter] Free

Predictive value of the steady-state peripheral blood progenitor cell (PBPC) counts for the yield of PBPC collected by leukapheresis after mobilization by granulocyte colony-stimulating factor (G-CSF) alone or chemotherapy and G-CSF [letter; comment] Free

Email alerts

ASH Publications

American Society of Hematology

Photograph

Treatment of chronic myelogenous leukemia: current status and investigational options [see comments]

Ex vivo expansion of hematopoietic precursors, progenitors, and stem cells: the next generation of cellular therapeutics

Cloning of human Bcl-2 homologue: inflammatory cytokines induce human A1 in cultured endothelial cells

Retroviral-mediated gene correction for X-linked severe combined immunodeficiency

Correction of interleukin-2 receptor function in X-SCID lymphoblastoid cells by retrovirally mediated transfer of the gamma-c gene

gamma-c gene transfer into SCID X1 patients' B-cell lines restores normal high-affinity interleukin-2 receptor expression and function

A point mutation in the catalytic domain of c-kit induces growth factor independence, tumorigenicity, and differentiation of mast cells

Molecular cloning of complex chromosomal translocation t(8;14;12)(q24.1;q32.3;q24.1) in a Burkitt lymphoma cell line defines a new gene (BCL7A) with homology to caldesmon

A randomized phase-III study of the efficacy of granulocyte colony- stimulating factor in children with high-risk acute lymphoblastic leukemia. Berlin-Frankfurt-Munster Study Group

Murine JAK3 is preferentially expressed in hematopoietic tissues and lymphocyte precursor cells

Hematopoietic progenitors and interleukin-3-dependent cell lines synthesize histamine in response to calcium ionophore

Involvement of peripheral benzodiazepine receptors in the protection of hematopoietic cells against oxygen radical damage

Aplastic anemia: evidence for dysfunctional bone marrow progenitor cells and the corrective effect of granulocyte colony-stimulating factor in vitro

Genetic basis of hypo-responsiveness of A/J mice to interleukin-3

Stem cell factor enhances interleukin-3 dependent induction of 68-kD calmodulin-binding protein and thymidine kinase activity in NFS-60 cells

Xenogeneic expression of human stem cell factor in transgenic mice mimics codominant c-kit mutations

Effect of recombinant erythropoietin in interaction with stromal factors on cord blood hematopoiesis

A novel hematopoietic multilineage clone, Myl-D-7, is stromal cell- dependent and supported by an alternative mechanism(s) independent of stem cell factor/c-kit interaction

Stromal fibroblast heparan sulfate is required for cytokine-mediated ex vivo maintenance of human long-term culture-initiating cells

Engraftment potential of different sources of human hematopoietic progenitor cells in BNX Mice

Plasma from patients with idiopathic and human immunodeficiency virus- associated thrombotic thrombocytopenic purpura induces apoptosis in microvascular endothelial cells

A novel DNA inversion causing severe hemophilia A

Human beta2-glycoprotein I as an anticardiolipin cofactor determined using mutants expressed by a baculovirus system

Platelet-dependent primary hemostasis promotes selectin- and integrin- mediated neutrophil adhesion to damaged endothelium under flow conditions

Increased soluble interleukin-1 type II receptor concentrations in postoperative patients and in patients with sepsis syndrome

Autoantibodies inhibit interleukin-7-mediated proliferation and are associated with the age-dependent loss of pre-B cells in autoimmune New Zealand Black Mice

Clonal populations of CD4+ and CD8+ T cells in patients with multiple myeloma and paraproteinemia

Interleukin-13 (IL-13) induces IL-1 receptor antagonist gene expression and protein synthesis in peripheral blood mononuclear cells: inhibition by an IL-4 mutant protein

Coexpression of the interleukin-13 and interleukin-4 genes correlates with their physical linkage in the cytokine gene cluster on human chromosome 5q23-31

Interleukin-15 promotes the growth of leukemic cells of patients with B- cell chronic lymphoproliferative disorders

Migration of human monocytes in response to vascular endothelial growth factor (VEGF) is mediated via the VEGF receptor flt-1

Expression of the interleukin-2 receptor gamma chain on cord blood mononuclear cells

p53 gene mutations and protein overexpression are associated with aggressive variants of mantle cell lymphomas

Cyclin E overexpression in relapsed adult acute lymphoblastic leukemias of B-cell lineage

Acute lymphoblastic leukemia of childhood: identification of two distinct regions of deletion on the short arm of chromosome 12 in the region of TEL and KIP1

Plasma cells induce apoptosis of pre-B cells by interacting with bone marrow stromal cells

Enhancement of activity of 1alpha, 25-dihydroxyvitamin D3 for growth inhibition and differentiation induction of human myelomonocytic leukemia cells by tretinoin tocoferil, an alpha-tocopherol ester of all- trans retinoic acid

Enhanced metabolism of 1-beta-D-arabinofuranosylcytosine in Down syndrome cells: a contributing factor to the superior event free survival of Down syndrome children with acute myeloid leukemia

Establishment of a human acute promyelocytic leukemia-ascites model in SCID mice

Transactivation of the interleukin-1alpha promoter by human T-cell leukemia virus type I and type II Tax proteins

Peripheral blood mononuclear cells of a patient with advanced Hodgkin's lymphoma give rise to permanently growing Hodgkin-Reed Sternberg cells

Molecular single cell analysis demonstrates the derivation of a peripheral blood-derived cell line (L1236) from the Hodgkin/Reed- Sternberg cells of a Hodgkin's lymphoma patient

The t(2;5) chromosomal translocation is not a common feature of primary cutaneous CD30+ lymphoproliferative disorders: comparison with anaplastic large-cell lymphoma of nodal origin [see comments]

The diadenosine polyphosphates Ap3A and Ap4A and adenosine triphosphate interact with granulocyte-macrophage colony-stimulating factor to delay neutrophil apoptosis: implications for neutrophil: platelet interactions during inflammation

Neutrophil deactivation by influenza A viruses: mechanisms of protection after viral opsonization with collectins and hemagglutination-inhibiting antibodies

Reduced invasion and growth of Plasmodium falciparum into elliptocytic red blood cells with a combined deficiency of protein 4.1, glycophorin C, and p55

Associations of iron overload in Africa with hepatocellular carcinoma and tuberculosis: Strachan's 1929 thesis revisited

Distribution of iron in reticulocytes after inhibition of heme synthesis with succinylacetone: examination of the intermediates involved in iron metabolism

Cholesterol-loading of membranes of normal erythrocytes inhibits phospholipid repair and arachidonoyl-CoA:1-palmitoyl-sn-glycero-3- phosphocholine acyl transferase. A model of spur cell anemia

Persistence of mixed chimerism in patients transplanted for the treatment of thalassemia

The repopulation potential of fetal liver hematopoietic stem cells in mice exceeds that of their liver adult bone marrow counterparts

Allogenic transplant of canine peripheral blood stem cells mobilized by recombinant canine hematopoietic growth factors

Cytogenetic abnormalities in adult acute lymphoblastic leukemia: correlations with hematologic findings outcome. A Collaborative Study of the Group Francais de Cytogenetique Hematologique [published erratum appears in Blood 1996 Oct 1;88(7):2818]

FK506 (Tacrolimus) monotherapy for prevention of graft-versus-host disease after histocompatible sibling allogenic bone marrow transplantation

Similarities between T-cell chronic lymphocytic leukemia and the small- cell variant of T-prolymphocytic leukemia [letter; comment]

Human immunodeficiency virus-1 infection, homosexuality, and Kaposi- associated herpes-like DNA in peripheral blood mononuclear cells [letter]

Lymphocyte transfusion therapy for cancer patients [letter]

Pure red blood cell aplasia associated with parvovirus B19 infection in large granular lymphocyte leukemia [letter]

Potentiation of neutrophil functions with administration of granulocyte colony-stimulating factor to donors for granulocyte transfusions [letter; comment]

Possible misdiagnosis of factor VIII gene inversion in a case of severe hemophilia A [letter]

2-Chlorodeoxyadenosine as first-line treatment in bronchus-associated lymphoid tissue lymphoma [letter]

Predictive value of the steady-state peripheral blood progenitor cell (PBPC) counts for the yield of PBPC collected by leukapheresis after mobilization by granulocyte colony-stimulating factor (G-CSF) alone or chemotherapy and G-CSF [letter; comment]