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The combination of bendamustine, bortezomib, and rituximab for patients with relapsed/refractory indolent and mantle cell non-Hodgkin lymphoma
Free
Somatic KRAS mutations associated with a human nonmalignant syndrome of autoimmunity and abnormal leukocyte homeostasis
Free
Autoimmune lymphoproliferative syndrome–like disease with somatic KRAS mutation
Free
Molecular and clinical features of the myeloproliferative neoplasm associated with JAK2 exon 12 mutations
Free
CNS involvement and treatment with interferon-α are independent prognostic factors in Erdheim-Chester disease: a multicenter survival analysis of 53 patients
Free
Systemic perturbation of cytokine and chemokine networks in Erdheim-Chester disease: a single-center series of 37 patients
Free
Prevalence of 25-hydroxyvitamin D deficiency in subgroups of elderly persons with anemia: association with anemia of inflammation
Free
Issue Archive
March 10 2011
Table of Contents
Inside Blood
Editorial
Review Article
How I Treat
Blood Consult
Gene therapy
Therapeutic levels of fetal hemoglobin in erythroid progeny of β-thalassemic CD34+ cells after lentiviral vector-mediated gene transfer Free
Andrew Wilber,Phillip W. Hargrove,Yoon-Sang Kim,Janice M. Riberdy,Vijay G. Sankaran,Eleni Papanikolaou,Maria Georgomanoli,Nicholas P. Anagnou,Stuart H. Orkin,Arthur W. Nienhuis,Derek A. Persons
Hematopoiesis and Stem Cells
Two distinct auto-regulatory loops operate at the PU.1 locus in B cells and myeloid cells Free
Mathias Leddin,Chiara Perrod,Maarten Hoogenkamp,Saeed Ghani,Salam Assi,Sven Heinz,Nicola K. Wilson,George Follows,Jörg Schönheit,Lena Vockentanz,Ali M. Mosammam,Wei Chen,Daniel G. Tenen,David R. Westhead,Berthold Göttgens,Constanze Bonifer,Frank Rosenbauer
Immunobiology
Lymphoid Neoplasia
The combination of bendamustine, bortezomib, and rituximab for patients with relapsed/refractory indolent and mantle cell non-Hodgkin lymphoma
Free
Clinical Trials & Observations
Jonathan W. Friedberg,Julie M. Vose,Jennifer L. Kelly,Faith Young,Steven H. Bernstein,Derick Peterson,Lynn Rich,Susan Blumel,Nicole K. Proia,Jane Liesveld,Richard I. Fisher,James O. Armitage,Steven Grant,John P. Leonard
Somatic KRAS mutations associated with a human nonmalignant syndrome of autoimmunity and abnormal leukocyte homeostasis
Free
Brief Report
Julie E. Niemela,Lianghao Lu,Thomas A. Fleisher,Joie Davis,Iusta Caminha,Marc Natter,Laurel A. Beer,Kennichi C. Dowdell,Stefania Pittaluga,Mark Raffeld,V. Koneti Rao,João B. Oliveira
Autoimmune lymphoproliferative syndrome–like disease with somatic KRAS mutation
Free
Brief Report
Masatoshi Takagi,Kunihiro Shinoda,Jinhua Piao,Noriko Mitsuiki,Mari Takagi,Kazuyuki Matsuda,Hideki Muramatsu,Sayoko Doisaki,Masayuki Nagasawa,Tomohiro Morio,Yoshihito Kasahara,Kenichi Koike,Seiji Kojima,Akira Takao,Shuki Mizutani
Hyperphosphorylated paratarg-7: a new molecularly defined risk factor for monoclonal gammopathy of undetermined significance of the IgM type and Waldenström macroglobulinemia Free
Sandra Grass,Klaus-Dieter Preuss,Alexandra Wikowicz,Evangelos Terpos,Marita Ziepert,Diana Nikolaus,Yin Yang,Natalie Fadle,Evi Regitz,Meletios A. Dimopoulos,Steven P. Treon,Zachary R. Hunter,Michael Pfreundschuh
Induction of Ca2+-driven apoptosis in chronic lymphocytic leukemia cells by peptide-mediated disruption of Bcl-2–IP3 receptor interaction Free
Fei Zhong,Michael W. Harr,Geert Bultynck,Giovanni Monaco,Jan B. Parys,Humbert De Smedt,Yi-Ping Rong,Jason K. Molitoris,Minh Lam,Christopher Ryder,Shigemi Matsuyama,Clark W. Distelhorst
Myeloid Neoplasia
Molecular and clinical features of the myeloproliferative neoplasm associated with JAK2 exon 12 mutations
Free
Brief Report
Francesco Passamonti,Chiara Elena,Susanne Schnittger,Radek C. Skoda,Anthony R. Green,François Girodon,Jean-Jacques Kiladjian,Mary Frances McMullin,Marco Ruggeri,Carles Besses,Alessandro M. Vannucchi,Eric Lippert,Heinz Gisslinger,Elisa Rumi,Thomas Lehmann,Christina A. Ortmann,Daniela Pietra,Cristiana Pascutto,Torsten Haferlach,Mario Cazzola
Novel imatinib-sensitive PDGFRA-activating point mutations in hypereosinophilic syndrome induce growth factor independence and leukemia-like disease Free
Christian Elling,Philipp Erben,Christoph Walz,Marie Frickenhaus,Mirle Schemionek,Martin Stehling,Hubert Serve,Nicholas C. P. Cross,Andreas Hochhaus,Wolf-Karsten Hofmann,Wolfgang E. Berdel,Carsten Müller-Tidow,Andreas Reiter,Steffen Koschmieder
Phagocytes, Granulocytes, and Myelopoiesis
CNS involvement and treatment with interferon-α are independent prognostic factors in Erdheim-Chester disease: a multicenter survival analysis of 53 patients
Free
Clinical Trials & Observations
Laurent Arnaud,Baptiste Hervier,Antoine Néel,Mohamed A. Hamidou,Jean-Emmanuel Kahn,Bertrand Wechsler,Gemma Pérez-Pastor,Bjørn Blomberg,Jean-Gabriel Fuzibet,François Dubourguet,António Marinho,Catherine Magnette,Violaine Noel,Michel Pavic,Jochen Casper,Anne-Bérangère Beucher,Nathalie Costedoat-Chalumeau,Laurent Aaron,Juan Salvatierra,Carlos Graux,Patrice Cacoub,Véronique Delcey,Claudia Dechant,Pascal Bindi,Christiane Herbaut,Giorgio Graziani,Zahir Amoura,Julien Haroche
Systemic perturbation of cytokine and chemokine networks in Erdheim-Chester disease: a single-center series of 37 patients
Free
Clinical Trials & Observations
Laurent Arnaud,Guy Gorochov,Frédéric Charlotte,Virginie Lvovschi,Christophe Parizot,Martin Larsen,Pascale Ghillani-Dalbin,Baptiste Hervier,Jean-Emmanuel Kahn,Claire Deback,Lucile Musset,Zahir Amoura,Julien Haroche
The nerve growth factor reduces APOBEC3G synthesis and enhances HIV-1 transcription and replication in human primary macrophages Free
Thiago Moreno L. Souza,Diego Q. Rodrigues,Caroline P. B. Passaes,Victor Barreto-de-Souza,Renato S. Aguiar,Jairo R. Temerozo,Mariza G. Morgado,Carlos Frederico L. Fontes,Elizabeth G. Araujo,Dumith Chequer Bou-Habib
Red Cells, Iron, and Erythropoiesis
Prevalence of 25-hydroxyvitamin D deficiency in subgroups of elderly persons with anemia: association with anemia of inflammation
Free
Clinical Trials & Observations
Modulation of hepcidin production during hypoxia-induced erythropoiesis in humans in vivo: data from the HIGHCARE project Free
Alberto Piperno,Stefania Galimberti,Raffaella Mariani,Sara Pelucchi,Giulia Ravasi,Carolina Lombardi,Grzegorz Bilo,Miriam Revera,Andrea Giuliano,Andrea Faini,Veronica Mainini,Mark Westerman,Tomas Ganz,Maria Grazia Valsecchi,Giuseppe Mancia,Gianfranco Parati,for the HIGHCARE investigators
Thrombosis and Hemostasis
Transplantation
Immune reconstitution is preserved in hematopoietic stem cell transplantation coadministered with regulatory T cells for GVHD prevention Free
Aline Gaidot,Dan Avi Landau,Gaëlle Hélène Martin,Olivia Bonduelle,Yenkel Grinberg-Bleyer,Diana Matheoud,Sylvie Grégoire,Claude Baillou,Béhazine Combadière,Eliane Piaggio,José Laurent Cohen
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Cover Image
Cover Image
Peripheral smear illustrating characteristic morphologic findings in LGL leukemia. See the article by Lamy and Loughran on page 2764.
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