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Journal Articles

TP53-mutant variant allele frequency and cytogenetics determine prognostic groups in MDS/AML for transplantation

Open Access
Clinical Trials & Observations
Konstantinos Lontos, Rima M. Saliba, Rashmi Kanagal-Shamanna, Gonca Özcan, Jeremy Ramdial, George Chen, Tapan Kadia, Nicholas James Short, Naval G. Daver, Hagop Kantarjian, David Marin, Partow Kebriaei, Uday Popat, Richard Champlin, Elizabeth Shpall, Betül Oran
Journal: Blood Advances
Blood Adv (2025) 9 (11): 2845–2854.
https://doi.org/10.1182/bloodadvances.2024014499
Published: 2025
Journal Articles

Improved outcomes and treatment guidance in pediatric therapy-related AML: AML-BFM study group recommendations

Open Access
Clinical Trials & Observations
Stephanie Sendker, Markus Schneider, Evangelia Antoniou, Daniel Neumann, Naghmeh Niktoreh, Uta Dirksen, Nils von Neuhoff, Ursula Creutzig, Dirk Reinhardt, Katharina Waack
Journal: Blood Advances
Blood Adv (2025) 9 (11): 2831–2841.
https://doi.org/10.1182/bloodadvances.2024014728
Published: 2025
Includes: Supplemental data
Journal Articles

A cure for the kiss of death?

Open Access
Clinical Trials & Observations
Jacob S. Appelbaum, Mary-Elizabeth Percival, Bart L. Scott
Journal: Blood Advances
Blood Adv (2025) 9 (11): 2855–2856.
https://doi.org/10.1182/bloodadvances.2025015850
Published: 2025
Journal Articles

On the road to improved therapies for therapy-related AML

Open Access
Clinical Trials & Observations
Alexandra McLean Stevens, Todd M. Cooper
Journal: Blood Advances
Blood Adv (2025) 9 (11): 2842–2844.
https://doi.org/10.1182/bloodadvances.2025015987
Published: 2025
Journal Articles

Hematological phenotypes in GATA2 deficiency syndrome arise from aging, maladaptation to proliferation, and somatic events

Open Access
Juncal Fernandez-Orth, Cansu Koyunlar, Julia M. Weiss, Emanuele Gioacchino, Hans de Looper, Geoffroy Andrieux, Mariëtte ter Borg, Joke Zink, Irene Gonzalez-Menendez, Remco Hoogenboezem, Baris Yigit, Kirsten J. Gussinklo, Roger Mulet-Lazaro, Charlotte Wantzen, Sophie Pfeiffer, Christian Molnar, Eric Bindels, Sheila Bohler, Mathijs Sanders, Leticia Quintanilla-Martinez, Marcin Wlodarski, Melanie Boerries, Ivo P. Touw, Charlotte Niemeyer, Miriam Erlacher, Emma de Pater
Journal: Blood Advances
Blood Adv (2025) 9 (11): 2794–2807.
https://doi.org/10.1182/bloodadvances.2024015106
Published: 2025
Includes: Supplemental data
Journal Articles

Thrombosis, major bleeding, and mortality in 1079 patients with myelofibrosis: a matched population-based study

Open Access
Anneli Enblom Larsson, Henrik Renlund, Björn Andréasson, Henrik Holmberg, Maria Liljeholm, Anders Själander
Journal: Blood Advances
Blood Adv (2025) 9 (11): 2783–2793.
https://doi.org/10.1182/bloodadvances.2025016247
Published: 2025
Includes: Supplemental data
Journal Articles

Emergent BAX-mutated clonal hematopoiesis after venetoclax-based therapy for breast cancer

Open Access
Ing-Soo S Tiong, Tamia Nguyen, Chong Chyn Chua, Charis E Teh, Christine Muttiah, Sarah Ftouni, John F Seymour, Daniel H D Gray, Andrew W Roberts, Sarah-Jane Dawson, Geoffrey J Lindeman, Piers Blombery
Journal: Blood Advances
Blood Adv bloodadvances.2025016063.
https://doi.org/10.1182/bloodadvances.2025016063
Published: 2025
Includes: Supplemental data
Journal Articles

A Revised Prognostic Model for Patients with Acute Myeloid Leukemia and First Relapse

Open Access
Niek G. Van Der Maas, Dimitri A. Breems, Clara P.W. Klerk, Thomas Pabst, Patrycja Gradowska, Abin Thomas, Bart J. Biemond, Jürgen Kuball, Catharina H.M.J. van Elssen, Otto J. Visser, Marie-Christiane Madeleine Vekemans, Carlos Graux, Johan A. Maertens, Steven Knapper, Mike Dennis, Sylvie D Freeman, Ian Thomas, Berna H Beverloo, Gerwin A Huls, Charles Craddock, Peter J.M. Valk, Paresh Vyas, Nigel H. Russell, Gert J Ossenkoppele, Bob Löwenberg, Jan J. Cornelissen, Jurjen Versluis
Journal: Blood Advances
Blood Adv bloodadvances.2025015797.
https://doi.org/10.1182/bloodadvances.2025015797
Published: 2025
Includes: Supplemental data
Journal Articles

RAS Mutation Identifies a Poor Prognostic Molecular Subtype of Therapy-Related Myeloid Neoplasm

Open Access
Chung Hoow Kok, Aref Al-Kali, Daniel Thomas, Rong He, Monika M Kutyna, Hassan B Alkhateeb, Kelly Lim, Antoine N. Saliba, Carla Toop, Aasiya Matin, Hamish S Scott, Naseema Gangat, Anna L Brown, Abhishek A. Mangaonkar, Christopher N Hahn, Kebede Begna, Kevin Hung, Patricia T. Greipp, William J Hogan, Mrinal M. Patnaik, Mithun Vinod Shah, Devendra K. Hiwase
Journal: Blood Advances
Blood Adv bloodadvances.2025016374.
https://doi.org/10.1182/bloodadvances.2025016374
Published: 2025
Includes: Supplemental data
Journal Articles

Safety run-in and part 1 of GIMEMA AML1718: venetoclax combined with FLAI as induction treatment in non–low-risk AML

Open Access
Clinical Trials & Observations
Giovanni Marconi, Alfonso Piciocchi, Ernesta Audisio, Cristina Papayannidis, Marco Cerrano, Clara Minotti, Francesca Paoloni, Fabio Guolo, Monica Bocchia, Michela Rondoni, Albana Lico, Matteo G. Carrabba, Matteo Giovanni Della Porta, Marco Frigeni, Luisa Giaccone, Germana Beltrami, Chiara Cattaneo, Maria Chiara Di Chio, Bianca Serio, Enrico Crea, Roberto Freilone, Saveria Capria, Antonio Curti, Paola Minetto, Edoardo la Sala, Jacopo Nanni, Beatrice Anna Zannetti, Giorgia Simonetti, Maria Teresa Bochicchio, Giuseppe Saglio, Roberto M. Lemoli, Adriano Venditti, Marco Vignetti, Paola Fazi, Giovanni Martinelli
Journal: Blood Advances
Blood Adv (2025) 9 (10): 2542–2552.
https://doi.org/10.1182/bloodadvances.2024014901
Published: 2025
Includes: Supplemental data
Journal Articles

Characterization and treatment outcomes of malignant histiocytoses in a retrospective series of 141 cases in France

Open Access
Clinical Trials & Observations
Camille Bigenwald, Damien Roos-Weil, Arnaud Pagès, Zofia Hélias-Rodzewicz, Christiane Copie-Bergman, Marzieh Nashvi, Pierre Khneisser, Marie Parrens, Alexandra Traverse-Glehen, Isabelle Ray-Coquard, Loïc Ysebaert, Tony Marchand, Jérôme Razanamahery, Frédéric Charlotte, Antoine Neel, Gandhi Damaj, Jérémie Dion, Eve-Marie Nazal-Traissac, Stéphanie Tardy, Géraldine Salmeron, Hélène Monjanel, Ahmed Idbaih, Sébastien Héritier, Julien Haroche, Jean Donadieu, Jean-François Emile
Journal: Blood Advances
Blood Adv (2025) 9 (10): 2530–2541.
https://doi.org/10.1182/bloodadvances.2024015208
Published: 2025
Includes: Supplemental data
Journal Articles

Assessing AML-based risk criteria in patients with accelerated/blast-phase MPN treated with less-intensive therapy

Open Access
Reid Shaw, James J. Yoon, Hannah Johnston, Marta B. Davidson, Alexa J. Siddon, Rory M. Shallis, Evan C. Chen, Madelyn Burkart, Timothy S. Oh, Sunil G. Iyer, Ellen Madarang, Chandrasekar Muthiah, Joshua Kassner, Raajit K. Rampal, Guru Subramanian Guru Murthy, Terrence Bradley, Yasmin Abaza, Jacqueline S. Garcia, Vikas Gupta, Kristen M. Pettit, Olatoyosi Odenike, Anand A. Patel
Journal: Blood Advances
Blood Adv (2025) 9 (10): 2453–2457.
https://doi.org/10.1182/bloodadvances.2024015712
Published: 2025
Includes: Supplemental data
Journal Articles

Cytogenetic annotation automation in myelodysplastic syndrome research databases

Open Access
Samuel Urrutia, Kelly S. Chien, Ziyi Li, Alexandre Bazinet, Guilin Tang, Guillermo Garcia-Manero
Journal: Blood Advances
Blood Adv (2025) 9 (10): 2428–2430.
https://doi.org/10.1182/bloodadvances.2024015362
Published: 2025
Includes: Supplemental data
Journal Articles

Drug development for leukemia: comprehensive analysis of clinical trials from first report to drug approval

Open Access
Kellen Cristine Tjioe, Marisol Miranda Galvis, Kenza Mamouni, Thalyta Freitas, Muhannad Sharara, Brenda Santellano, Claudia Guillen, Jorge Cortes
Journal: Blood Advances
Blood Adv bloodadvances.2024014340.
https://doi.org/10.1182/bloodadvances.2024014340
Published: 2025
Includes: Supplemental data
Journal Articles

Response to "It might not be whether you get knocked down, but whether you..."

Open Access
Wei Ying Jen, Nicholas J Short
Journal: Blood Advances
Blood Adv bloodadvances.2025016766.
https://doi.org/10.1182/bloodadvances.2025016766
Published: 2025
Journal Articles

Asciminib remained superior vs bosutinib in late-line CML-CP after nearly 4 years of follow-up in ASCEMBL

Open Access
Michael J. Mauro, MD, Yosuke Minami, Andreas Hochhaus, Elza Lomaia, Sergey Voloshin, Anna Turkina, Dong-Wook Kim, Jane F Apperley, Jorge Cortes, Andre Abdo, Laura Maria Fogliato, Dennis Dong Hwan Kim, Philipp le Coutre, Susanne Saussele, Mario Annunziata, Timothy P Hughes, Naeem Chaudhri, Lynette Chee, Valentin Garcia-Gutierrez, Koji Sasaki, Carla Boquimpani, Shruti Kapoor, Noemi Espurz-Abad, Vishal Dhamal, Delphine Rea
Journal: Blood Advances
Blood Adv bloodadvances.2025016042.
https://doi.org/10.1182/bloodadvances.2025016042
Published: 2025
Includes: Supplemental data
Journal Articles

Clec12a is required for the pathogenesis of NUP98::NSD1 AML

Open Access
Sagarajit Mohanty, Fiorella Charles Cano, Razif Gabdoulline, Courteney K Lai, Basem Othman, Harish Sudarsanam, Thomas Eder, Florian Grebien, Daniel B. Lipka, Reinhard Henschler, Michael Heuser
Journal: Blood Advances
Blood Adv bloodadvances.2024015739.
https://doi.org/10.1182/bloodadvances.2024015739
Published: 2025
Includes: Supplemental data
Journal Articles

NTRK1-rearranged histiocytosis: clinicopathologic and molecular features

Open Access
Rivers Fragneau, Sylvie Fraitag, Paul G Kemps, Zofia Hélias-Rodzewicz, Somak Roy, Benjamin Bonsang, Allison L Bartlett, Subhra Dhar, Martin Jankofsky, Jozef Zlocha, Karel Svojgr, Lenka Krsková, Andrica C.H. de Vries, Robert M. Verdijk, Jan AM van Laar, Roos Leguit, Philippe Drabent, Eric D. Carlsen, Jonhan Ho, Arivarasan Karunamurthy, Mariarita Santi, Marie-Laure Jullie, Florian Babor, Robert Lorsbach, Astrid G.S. van Halteren, Sébastien Héritier, Eli L Diamond, Benjamin H. Durham, Ashish R. Kumar, Arunaloke Bhattacharya, Julien Haroche, MD, PhD, Jean Donadieu, Arndt Borkhardt, Jennifer Picarsic, Jean-Francois Emile
Journal: Blood Advances
Blood Adv bloodadvances.2025016167.
https://doi.org/10.1182/bloodadvances.2025016167
Published: 2025
Includes: Supplemental data
Journal Articles

Finding the right fit: assessment of fitness in AML

Open Access
Clinical Trials & Observations
Nicholas Chornenki, Lee Mozessohn
Journal: Blood Advances
Blood Adv (2025) 9 (9): 2300–2301.
https://doi.org/10.1182/bloodadvances.2025016114
Published: 2025
Journal Articles

Real-world effectiveness of immunoglobulin replacement for hypogammaglobulinemia and infections in multiple myeloma

Open Access
Elizabeth O'Donnell, Thais Gift, Zaid Yousif, Nikhil Khandelwal, Raj Desai, Lynn Huynh, Louise Clear, Megan Pinaire, Mingchen Ye, Azeem Banatwala, Gregory Belsky, Yichuan Grace Hsieh, Christopher Herrick, Mei Sheng Duh, Shawn N. Murphy, Marie Sanchirico
Journal: Blood Advances
Blood Adv bloodadvances.2024015477.
https://doi.org/10.1182/bloodadvances.2024015477
Published: 2025
Includes: Supplemental data