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Journal Articles

The Anti-Leukemia Effect of Natural Killer-Derived Exosomes

Michael Anbar, PhD, Galit Granot, PhD, Pia Raanani, MD, Uri Rozovski, MD

Blood (2019) 134 (Supplement_1): 4652.

https://doi.org/10.1182/blood-2019-129986

Published: 2019

Journal Articles

CLL-Derived Exosomes Function As Trojan Horses That Induce SMAD6-Dependent Apoptosis of Normal B-Cells

Orit Uziel, PhD, Zinab Sarsur- Amer, Einat Beery, Pia Raanani, MD, Uri Rozovski, MD

Blood (2019) 134 (Supplement_1): 1734.

https://doi.org/10.1182/blood-2019-129873

Published: 2019

Journal Articles

The Infection-Driven Production/Secretion of Inflammatory Cytokines By Circulating Monocytes of Myelofibrosis Is Defective and Is Reactivated after In Vivo JAK1/2 Inhibition

Martina Barone, PhD, Francesca Ricci, BS, Marco Romano, PhD, Dorian Forte, PhD, Giuseppe Auteri, MD, Francesco Fabbri, PhD, Emanuela Ottaviani, Pierluigi Tazzari, MD, Nicola Vianelli, MD, Giovanni Martinelli, MD, Michele Cavo, Francesca Palandri, PhD MD, Lucia Catani

Blood (2019) 134 (Supplement_1): 1686.

https://doi.org/10.1182/blood-2019-127322

Published: 2019

Journal Articles

The Malignant Hemopoietic Clone of Triple Negative Patients with Myelofibrosis Shows in Vitro Functional Defects but Is Highly Responsive to the Pro-Survival Signals of Circulating Autologous Microvesicles

Blood (2018) 132 (Supplement 1): 4334.

https://doi.org/10.1182/blood-2018-99-114507

Published: 2018

Journal Articles

Exosomes Derived from Cancer Associated Fibroblasts Elicit Survival and Drug Resistance of Primary Lymphoma Cells

Shunsuke Kunou, Kazuyuki Shimada, MD PhD, Tomoya Hikita, PhD, Tomohiro Aoki, MD PhD, Akihiko Sakamoto, PhD, Fumihiko Hayakawa, MD, PhD, Chitose Oneyama, PhD, Hitoshi Kiyoi, MD PhD

Blood (2018) 132 (Supplement 1): 4128.

https://doi.org/10.1182/blood-2018-99-111863

Published: 2018

Journal Articles

CRISPR/Cas9-Mediated Disruption of PD-L1 Reduces the T Cell Suppressive Effect of Wharton's Jelly Mesenchymal Stromal Cells and Their Extracellular Vesicles

Neil Dunavin, MD, Meizhang Li, PhD, Safinur Atay, PhD, Jim Mitchell, Rupal Soder, PhD, Sunil Abhyankar, MD, Joseph P. McGuirk, DO, Andrew K Godwin, PhD, Buddhadeb Dawn, MD

Blood (2018) 132 (Supplement 1): 5095.

https://doi.org/10.1182/blood-2018-99-116921

Published: 2018

Journal Articles

Characterization of Circulating and Bone Marrow Derived Exosomes in Multiple Myeloma Patients

Bruna Velosa Ferreira, MD, Paulo Lucio, MD PhD, Manuel Neves, MD, Antonio Parreira, MD PhD, Bruno Costa-Silva, PhD, Cristina Joao, MD PhD MSc

Blood (2018) 132 (Supplement 1): 3172.

https://doi.org/10.1182/blood-2018-99-117656

Published: 2018

Journal Articles

Endothelial Cell-Derived Extracellular Vesicles Mitigate Radiation-Induced Hematopoietic Injury

Sadhna O. Piryani, BS, Yiqun Jiao, MD, Angel Y.F. Kam, PhD, Yang Liu, PhD, Tuan Vo-Dinh, PhD, Benny J. Chen, MD, Nelson J. Chao, MD, Phuong L. Doan, MD

Blood (2018) 132 (Supplement 1): 2581.

https://doi.org/10.1182/blood-2018-99-117058

Published: 2018

Journal Articles

MM-derived exosomes can promote apoptosis and inhibit proliferation of HD-CD4 + T, inhibit apoptosis and promote proliferation but inhibit perforin secretion of HD-CD8 + T, inhibit apoptosis and promote proliferation HD-Treg, and promotes IL-10 secretion

Rong Fu, PhD, Qing Shao, Liu Zhaoyun, Hui Liu, Jin Chen, Zonghong Shao, MD

Blood (2018) 132 (Supplement 1): 5602.

https://doi.org/10.1182/blood-2018-99-115998

Published: 2018

Journal Articles

Therapeutic Targeting of HSP90 in AML and ALL

Sanil Bhatia, PhD, Heinz Ahlert, Msc, Benedikt Frieg, PhD, Arndt Borkhardt, MD, Holger Gohlke, PhD, Thomas Kurz, Julia Hauer, MD

Blood (2018) 132 (Supplement 1): 4680.

https://doi.org/10.1182/blood-2018-99-120362

Published: 2018

Journal Articles

Proteomics Pathways of Sickle Cell Anemia (P2SCA): A Comprehensive Analysis By Liquid Chromatography Mass Spectrometry of Erythrocyte Membrane Proteins Characterized from the Muhimbili Sickle Cell Programme, Tanzania

Haddy KS Fye, PhD BSc, Paul Mrosso, Frédéric B Piel, PhD, Simon Davis, Roman Fischer, Gration Rwegasira, Benedikt Kessler, Julie Makani, MD PhD FRCP

Blood (2018) 132 (Supplement 1): 3653.

https://doi.org/10.1182/blood-2018-99-114650

Published: 2018

Journal Articles

Comparison of FXII Activation in Human Plasma By Extracellular Vesicles from Cancer Cells Versus Non-Transformed Cells

Dewen You, PhD, Victor Chatterjee, MD, Suman Kundu, MBA, Mohamed Samour, MBBS, Alvin H. Schmaier, MD, Alok A. Khorana, MD, Keith McCrae, MD

Blood (2017) 130 (Supplement 1): 3705.

https://doi.org/10.1182/blood.V130.Suppl_1.3705.3705

Published: 2017

Journal Articles

The Exosomes-Derived EGFR Ligand Amphiregulin (AREG) Is a New Pro-Osteoclastogenic Factor in Multiple Myeloma

Emanuela Vicario, PhD, Stefania Raimondo, PhD, Laura Saieva, PhD, Federica Costa, PhD, Vincenza Tinnirello, Fabrizio Accardi, MD, Franco Aversa, MD, Nicola Giuliani, MD PhD, Riccardo Alessandro, PhD

Blood (2017) 130 (Supplement 1): 1776.

https://doi.org/10.1182/blood.V130.Suppl_1.1776.1776

Published: 2017

Journal Articles

Development of a Novel Class of Microtubule Destabilizing Agents with Selectivity Against Diffuse Large B-Cell Lymphoma (DLBCL) with B-Cell Receptor (BCR) Activation

Benet Pera Gresely, PhD, Francisco de Asís Balaguer, BS, Mariano Gonzalo Cardenas, PhD, Maria Victoria Revuelta, PhD, Maria Nieves Calvo Vidal, PhD, Rossella Marullo, MD PhD, Nahuel Zamponi, PhD, Ildefonso Ismael Rodriguez Rivera, MD, Yong Ai, PhD, Joseph Fraser Glickman, MSPH, PhD, Isabel Barasoain, PhD, Fernando Díaz, PhD, Ari Melnick, MD, Fengtian Xue, PhD, Leandro Cerchietti, MD

Blood (2017) 130 (Supplement 1): 2546.

https://doi.org/10.1182/blood.V130.Suppl_1.2546.2546

Published: 2017

Journal Articles

Extracellular Vesicles Play an Important Role in Intercellular Communication Between Bone Marrow Stroma and Hematopoietic Progenitor Cells in Myeloproliferative Neoplasms

Teresa L. Ramos, Luis Ignacio Sánchez-Abarca, Beatriz Rosón, Alba Redondo, Concepción Rodríguez, Haidy Rodríguez, Rebeca Ortega, Ana Rico, Silvia Preciado, Olga López Villar, Sandra Muntión, José Ramón González-Porras, MD, Jesus Hernandez, MD, Javier de las Rivas, PhD, Ángel Hernández-Hernández, PhD, Fermín Sánchez-Guijo, MD PhD, Consuelo Del Cañizo, MD PhD

Blood (2016) 128 (22): 1957.

https://doi.org/10.1182/blood.V128.22.1957.1957

Published: 2016

Journal Articles

Hemoglobin S Oxidation Promotes Plasma-Derived Microparticle Membrane Alterations and Toxicity

Sirsendu Jana, PhD, Michael B Strader, PhD, Tigist Kassa, PhD, Fantao Meng, PhD, Wayne Hicks, PhD, Ivan Tarandovskiy, PhD, Silvia De Paoli, PhD, Jan Simak, PhD, Jeffery L Miller, MD, Laurel Mendelsohn, BSc., Jim Nichols, RSN, Swee Lay Thein, MD, John D. Belcher, PhD, Gregory M Vercellotti, MD, Abdu Alayash, PhD

Blood (2016) 128 (22): 856.

https://doi.org/10.1182/blood.V128.22.856.856

Published: 2016

Journal Articles

Platelet Proteins Cause Allergic Transfusion Reactions through an Immunoglobulin-Dependent Mechanism

Dong-Young Donna Lee, Igla Muskaj, William Savage, MD PhD

Blood (2016) 128 (22): 91.

https://doi.org/10.1182/blood.V128.22.91.91

Published: 2016

Journal Articles

A Short N-Terminal Fragment in Front of the A1 Domain of Von Willebrand Factor Prevents the A1 from Binding the Platelet By Masking a Region Clustered By Type 2B VWD Mutations

Wei Deng, PhD, Yingchun Wang, PhD, Pete Lollar, MD, Renhao Li, PhD

Blood (2016) 128 (22): 553.

https://doi.org/10.1182/blood.V128.22.553.553

Published: 2016

Journal Articles

Evaluation of Genetic Mutations in Plasma Exosomes As a Biomarker Tool for Detecting the Clonal Evolution of Leukemic Cells in Pediatric AML

Fabienne Kunz, Katarina Reinhardt, PhD, Nils Von Neuhoff, PhD, Karl Welte, MD, Dirk Reinhardt, MD PhD, Basant Kumar Thakur, PhD

Blood (2016) 128 (22): 1711.

https://doi.org/10.1182/blood.V128.22.1711.1711

Published: 2016

Journal Articles

Characterization of Factor VIII Immune Complexes By Analytical Ultracentrifugation

Pete Lollar, MD, Ernest T. Parker, John F. Healey, Christopher B. Doering, PhD

Blood (2016) 128 (22): 3787.

https://doi.org/10.1182/blood.V128.22.3787.3787

Published: 2016

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The Anti-Leukemia Effect of Natural Killer-Derived Exosomes

CLL-Derived Exosomes Function As Trojan Horses That Induce SMAD6-Dependent Apoptosis of Normal B-Cells

The Infection-Driven Production/Secretion of Inflammatory Cytokines By Circulating Monocytes of Myelofibrosis Is Defective and Is Reactivated after In Vivo JAK1/2 Inhibition

The Malignant Hemopoietic Clone of Triple Negative Patients with Myelofibrosis Shows in Vitro Functional Defects but Is Highly Responsive to the Pro-Survival Signals of Circulating Autologous Microvesicles

Exosomes Derived from Cancer Associated Fibroblasts Elicit Survival and Drug Resistance of Primary Lymphoma Cells

CRISPR/Cas9-Mediated Disruption of PD-L1 Reduces the T Cell Suppressive Effect of Wharton's Jelly Mesenchymal Stromal Cells and Their Extracellular Vesicles

Characterization of Circulating and Bone Marrow Derived Exosomes in Multiple Myeloma Patients

Endothelial Cell-Derived Extracellular Vesicles Mitigate Radiation-Induced Hematopoietic Injury

MM-derived exosomes can promote apoptosis and inhibit proliferation of HD-CD4 + T, inhibit apoptosis and promote proliferation but inhibit perforin secretion of HD-CD8 + T, inhibit apoptosis and promote proliferation HD-Treg, and promotes IL-10 secretion

Therapeutic Targeting of HSP90 in AML and ALL

Proteomics Pathways of Sickle Cell Anemia (P2SCA): A Comprehensive Analysis By Liquid Chromatography Mass Spectrometry of Erythrocyte Membrane Proteins Characterized from the Muhimbili Sickle Cell Programme, Tanzania

Comparison of FXII Activation in Human Plasma By Extracellular Vesicles from Cancer Cells Versus Non-Transformed Cells

The Exosomes-Derived EGFR Ligand Amphiregulin (AREG) Is a New Pro-Osteoclastogenic Factor in Multiple Myeloma

Development of a Novel Class of Microtubule Destabilizing Agents with Selectivity Against Diffuse Large B-Cell Lymphoma (DLBCL) with B-Cell Receptor (BCR) Activation

Extracellular Vesicles Play an Important Role in Intercellular Communication Between Bone Marrow Stroma and Hematopoietic Progenitor Cells in Myeloproliferative Neoplasms

Hemoglobin S Oxidation Promotes Plasma-Derived Microparticle Membrane Alterations and Toxicity

Platelet Proteins Cause Allergic Transfusion Reactions through an Immunoglobulin-Dependent Mechanism

A Short N-Terminal Fragment in Front of the A1 Domain of Von Willebrand Factor Prevents the A1 from Binding the Platelet By Masking a Region Clustered By Type 2B VWD Mutations

Evaluation of Genetic Mutations in Plasma Exosomes As a Biomarker Tool for Detecting the Clonal Evolution of Leukemic Cells in Pediatric AML

Characterization of Factor VIII Immune Complexes By Analytical Ultracentrifugation

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