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Journal Articles

T-ALL and the talented Mr IL7Rα

Free
Cuijuan Han, Panagiotis Ntziachristos
Journal: Blood
Blood (2021) 138 (12): 1003–1004.
https://doi.org/10.1182/blood.2021012184
Published: 2021
Journal Articles

Overexpression of wild-type IL-7Rα promotes T-cell acute lymphoblastic leukemia/lymphoma

Free
Ana Silva, Afonso R. M. Almeida, Ana Cachucho, João L. Neto, Sofie Demeyer, Mafalda de Matos, Thea Hogan, Yunlei Li, Jules Meijerink, Jan Cools, Ana Rita Grosso, Benedict Seddon, João T. Barata
Journal: Blood
Blood (2021) 138 (12): 1040–1052.
https://doi.org/10.1182/blood.2019000553
Published: 2021
Includes: Supplemental data
Journal Articles

14q32 rearrangements deregulating BCL11B mark a distinct subgroup of T-lymphoid and myeloid immature acute leukemia

Free
Danika Di Giacomo, Roberta La Starza, Paolo Gorello, Fabrizia Pellanera, Zeynep Kalender Atak, Kim De Keersmaecker, Valentina Pierini, Christine J. Harrison, Silvia Arniani, Martina Moretti, Nicoletta Testoni, Giovanna De Santis, Giovanni Roti, Caterina Matteucci, Renato Bassan, Peter Vandenberghe, Stein Aerts, Jan Cools, Beat Bornhauser, Jean-Pierre Bourquin, Rocco Piazza, Cristina Mecucci
Journal: Blood
Blood (2021) 138 (9): 773–784.
https://doi.org/10.1182/blood.2020010510
Published: 2021
Includes: Supplemental data
Journal Articles

Prognostic factors for CNS control in children with acute lymphoblastic leukemia treated without cranial irradiation

Free
Clinical Trials & Observations
Jingyan Tang, Jie Yu, Jiaoyang Cai, Li Zhang, Shaoyan Hu, Ju Gao, Hua Jiang, Yongjun Fang, Changda Liang, Xiuli Ju, Runming Jin, Xiaowen Zhai, Xuedong Wu, Xin Tian, Qun Hu, Ningling Wang, Hui Jiang, Lirong Sun, Alex W. K. Leung, Minghua Yang, Kaili Pan, Cheng Cheng, Yiping Zhu, Hui Zhang, Chunfu Li, Jun J. Yang, Chi-kong Li, Xiaofan Zhu, Shuhong Shen, Ching-Hon Pui
Journal: Blood
Blood (2021) 138 (4): 331–343.
https://doi.org/10.1182/blood.2020010438
Published: 2021
Includes: Supplemental data
Journal Articles

“Root”ing for successful T-ALL treatment

Free
Sathish K. R. Padi, Andrew S. Kraft
Journal: Blood
Blood (2021) 137 (18): 2422–2423.
https://doi.org/10.1182/blood.2020009748
Published: 2021
Journal Articles

Single-cell RNA-seq reveals developmental plasticity with coexisting oncogenic states and immune evasion programs in ETP-ALL

Free
Praveen Anand, Amy Guillaumet-Adkins, Valeriya Dimitrova, Huiyoung Yun, Yotam Drier, Noori Sotudeh, Anna Rogers, Madhu M. Ouseph, Monica Nair, Sayalee Potdar, Randi Isenhart, Jake A. Kloeber, Tushara Vijaykumar, Leili Niu, Tiffaney Vincent, Guangwu Guo, Julia Frede, Marian H. Harris, Andrew E. Place, Lewis B. Silverman, David T. Teachey, Andrew A. Lane, Daniel J. DeAngelo, Jon C. Aster, Bradley E. Bernstein, Jens G. Lohr, Birgit Knoechel
Journal: Blood
Blood (2021) 137 (18): 2463–2480.
https://doi.org/10.1182/blood.2019004547
Published: 2021
Includes: Supplemental data
Journal Articles

Integrative genomic analysis of pediatric T-cell lymphoblastic lymphoma reveals candidates of clinical significance

Free
Tasneem Khanam, Sarah Sandmann, Jochen Seggewiss, Charlotte Ruether, Martin Zimmermann, Allison B. Norvil, Christoph Bartenhagen, Gerrit Randau, Stephanie Mueller, Heidi Herbrueggen, Per Hoffmann, Stefan Herms, Lanying Wei, Marius Woeste, Christian Wuensch, Humaira Gowher, Ilske Oschlies, Wolfram Klapper, Wilhelm Woessmann, Martin Dugas, Birgit Burkhardt
Journal: Blood
Blood (2021) 137 (17): 2347–2359.
https://doi.org/10.1182/blood.2020005381
Published: 2021
Includes: Supplemental data
Journal Articles

IKZF1 alterations predict poor prognosis in adult and pediatric T-ALL

Free
Clinical Trials & Observations
Mathieu Simonin, Ludovic Lhermitte, Marie-Emilie Dourthe, Etienne Lengliné, Carlos Graux, Nathalie Grardel, Jean-Michel Cayuela, Isabelle Arnoux, Virginie Gandemer, Norbert Ifrah, Hervé Dombret, André Baruchel, Elizabeth Macintyre, Arnaud Petit, Nicolas Boissel, Vahid Asnafi
Journal: Blood
Blood (2021) 137 (12): 1690–1694.
https://doi.org/10.1182/blood.2020007959
Published: 2021
Includes: Supplemental data
Journal Articles

Unraveling a T-ALL Tapestri

Free
Ashley P. Ng
Journal: Blood
Blood (2021) 137 (6): 726–727.
https://doi.org/10.1182/blood.2020008467
Published: 2021
Journal Articles

Single-cell DNA amplicon sequencing reveals clonal heterogeneity and evolution in T-cell acute lymphoblastic leukemia

Free
Llucia Albertí-Servera, Sofie Demeyer, Inge Govaerts, Toon Swings, Jolien De Bie, Olga Gielen, Marco Brociner, Lucienne Michaux, Johan Maertens, Anne Uyttebroeck, Kim De Keersmaecker, Nancy Boeckx, Heidi Segers, Jan Cools
Journal: Blood
Blood (2021) 137 (6): 801–811.
https://doi.org/10.1182/blood.2020006996
Published: 2021
Includes: Supplemental data
Journal Articles

Detonating T-ALL

Free
Maksim Mamonkin
Journal: Blood
Blood (2020) 136 (11): 1218–1219.
https://doi.org/10.1182/blood.2020006991
Published: 2020
Journal Articles

Preclinical efficacy of humanized, non–FcγR-binding anti-CD3 antibodies in T-cell acute lymphoblastic leukemia

Free
Brief Report
Christine Tran Quang, Benedetta Zaniboni, Romain Humeau, Etienne Lengliné, Marie Emilie Dourthe, Rajkumar Ganesan, Sanjaya Singh, Justin M. Scheer, Vahid Asnafi, Jacques Ghysdael
Journal: Blood
Blood (2020) 136 (11): 1298–1302.
https://doi.org/10.1182/blood.2019003801
Published: 2020
Includes: Supplemental data
Journal Articles

Ldb1 is required for Lmo2 oncogene–induced thymocyte self-renewal and T-cell acute lymphoblastic leukemia

Free
LiQi Li, Apratim Mitra, Kairong Cui, Bin Zhao, Seeyoung Choi, Jan Y. Lee, Daniel B. Stamos, Dalal El-Khoury, Claude Warzecha, Karl Pfeifer, Joyce Hardwick, Keji Zhao, Bryan Venters, Utpal P. Davé, Paul E. Love
Journal: Blood
Blood (2020) 135 (25): 2252–2265.
https://doi.org/10.1182/blood.2019000794
Published: 2020
Includes: Supplemental data
Journal Articles

Targeting cytokine- and therapy-induced PIM1 activation in preclinical models of T-cell acute lymphoblastic leukemia and lymphoma

Free
Renate De Smedt, Julie Morscio, Lindy Reunes, Juliette Roels, Valentina Bardelli, Beatrice Lintermans, Wouter Van Loocke, Afonso Almeida, Laurence C. Cheung, Rishi S. Kotecha, Marc R. Mansour, Anne Uyttebroeck, Peter Vandenberghe, Roberta La Starza, Cristina Mecucci, Tim Lammens, Nadine Van Roy, Barbara De Moerloose, João T. Barata, Tom Taghon, Steven Goossens, Pieter Van Vlierberghe
Journal: Blood
Blood (2020) 135 (19): 1685–1695.
https://doi.org/10.1182/blood.2019003880
Published: 2020
Includes: Supplemental data
Journal Articles

How I treat newly diagnosed T-cell acute lymphoblastic leukemia and T-cell lymphoblastic lymphoma in children

Free
Clinical Trials & Observations
David T. Teachey, David O’Connor
Journal: Blood
Blood (2020) 135 (3): 159–166.
https://doi.org/10.1182/blood.2019001557
Published: 2020
Journal Articles

IL-7R is essential for leukemia-initiating cell activity of T-cell acute lymphoblastic leukemia

Free
Sara González-García, Marta Mosquera, Patricia Fuentes, Tiziana Palumbo, Adela Escudero, Antonio Pérez-Martínez, Manuel Ramírez, Anne E. Corcoran, Maria L. Toribio
Journal: Blood
Blood (2019) 134 (24): 2171–2182.
https://doi.org/10.1182/blood.2019000982
Published: 2019
Includes: Supplemental data
Journal Articles

AT1412, a Patient-Derived Antibody in Development for the Treatment of CD9 Positive Precursor B-Acute Lymphoblastic Leukemia

Free
Greta De Jong, Sophie E Levie, Remko Schotte, PhD, Wouter Pos, PhD, Daniel Go, Etsuko Yasuda, Madalina Cercel, Susan E van Hal-van Veen, Esmay Frankin, Anikó Szabó, MD, Julien Villaudy, PhD, Pauline M van Helden, PhD, Hans van Eenennaam, PhD, Hergen Spits, PhD, Anita W Rijneveld, MD PhD, Mette D Hazenberg, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4461.
https://doi.org/10.1182/blood-2019-127894
Published: 2019
Journal Articles

Leukemia-Associated HSC Vascular Niche Is Negatively Regulated By PERK of Unfolded Protein Response (UPR)

Free
Lan Zhou, MD, Cui Liu, MBBS, PhD, Stanley A Adoro, PhD BSc, MSc, Lechuang Chen, PhD, Diana Ramirez, PhD, Ge Jin, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2486.
https://doi.org/10.1182/blood-2019-127607
Published: 2019
Journal Articles

Targeting the Activating Mutations of NOTCH1 in T-Cell Lymphoblastic Leukemia with a New SERCA Inhibitor CAD204520

Free
Matteo Marchesini, PhD, Andrea Gherli, Anna Montanaro, Samuel Kitara, Claudia Sorrentino, Luca Pagliaro, Anne-Marie Lund Winter, Chiara Rompietti, Donatella Stilli, Federica Rizzi, Kimberly Stegmaier, MD, Paolo Sportoletti, William Dalby-Brown, Giovanni Roti
Journal: Blood
Blood (2019) 134 (Supplement_1): 407.
https://doi.org/10.1182/blood-2019-125616
Published: 2019
Journal Articles

Germline RUNX1 Variation and Predisposition to T-Cell Acute Lymphoblastic Leukemia in Children

Free
Yizhen Li, PhD, Maoxiang Qian, Meenakshi Devidas, PhD, Wentao Yang, PhD, Stuart S. Winter, MD, Kimberly P. Dunsmore, Colton A Smith, Ting-Nien Lin, Xuijie Zhao, Ranran Zhang, Julie M. Gastier Foster, Elizabeth A. Raetz, MD, William L. Carroll, MD, Karen R. Rabin, MD PhD, Wenjian Yang, Patrick A. Zweidler-McKay, MD PhD, Ching-Hon Pui, MD, William E. Evans, PharmD, Charles G. Mullighan, MBBS, MD, Stephen P. Hunger, MD, Mary V. Relling, PharmD, Mignon L. Loh, MD, Jun J. Yang, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 653.
https://doi.org/10.1182/blood-2019-125912
Published: 2019