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Journal Articles

Molecular and cellular features of CTLA-4 blockade for relapsed myeloid malignancies after transplantation

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Clinical Trials & Observations Brief Report
Livius Penter, Yi Zhang, Alexandra Savell, Teddy Huang, Nicoletta Cieri, Emily M. Thrash, Seunghee Kim-Schulze, Aashna Jhaveri, Jingxin Fu, Srinika Ranasinghe, Shuqiang Li, Wandi Zhang, Emma S. Hathaway, Matthew Nazzaro, Haesook T. Kim, Helen Chen, Magdalena Thurin, Scott J. Rodig, Mariano Severgnini, Carrie Cibulskis, Stacey Gabriel, Kenneth J. Livak, Corey Cutler, Joseph H. Antin, Sarah Nikiforow, John Koreth, Vincent T. Ho, Philippe Armand, Jerome Ritz, Howard Streicher, Donna Neuberg, F. Stephen Hodi, Sacha Gnjatic, Robert J. Soiffer, X. Shirley Liu, Matthew S. Davids, Pavan Bachireddy, Catherine J. Wu
Journal: Blood
Blood (2021) 137 (23): 3212–3217.
https://doi.org/10.1182/blood.2021010867
Published: 2021
Includes: Supplemental data
Journal Articles

T-cell activation profiles distinguish hemophagocytic lymphohistiocytosis and early sepsis

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Vandana Chaturvedi, Rebecca A. Marsh, Adi Zoref-Lorenz, Erika Owsley, Vijaya Chaturvedi, Trung C. Nguyen, Jordana R. Goldman, Michael M. Henry, Jay N. Greenberg, Stephan Ladisch, Michelle L. Hermiston, Michael Jeng, Ahmed Naqvi, Carl E. Allen, Hector R. Wong, Michael B. Jordan
Journal: Blood
Blood (2021) 137 (17): 2337–2346.
https://doi.org/10.1182/blood.2020009499
Published: 2021
Includes: Supplemental data
Journal Articles

A T-cell–redirecting bispecific G-protein–coupled receptor class 5 member D x CD3 antibody to treat multiple myeloma

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Kodandaram Pillarisetti, Suzanne Edavettal, Mark Mendonça, Yingzhe Li, Mark Tornetta, Alexander Babich, Nate Majewski, Matt Husovsky, Dara Reeves, Eileen Walsh, Diana Chin, Leopoldo Luistro, Jocelin Joseph, Gerald Chu, Kathryn Packman, Shoba Shetty, Yusri Elsayed, Ricardo Attar, François Gaudet
Journal: Blood
Blood (2020) 135 (15): 1232–1243.
https://doi.org/10.1182/blood.2019003342
Published: 2020
Includes: Supplemental data
Journal Articles

Supercharging your CAR

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Sneha Ramakrishna, Kara L. Davis
Journal: Blood
Blood (2020) 135 (9): 593–594.
https://doi.org/10.1182/blood.2019004469
Published: 2020
Journal Articles

Inhibition of inositol kinase B controls acute and chronic graft-versus-host disease

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Govindarajan Thangavelu, Jing Du, Katelyn G. Paz, Michael Loschi, Michael C. Zaiken, Ryan Flynn, Patricia A. Taylor, Andrew Kemal Kirchmeier, Angela Panoskaltsis-Mortari, Leo Luznik, Kelli P. MacDonald, Geoffrey R. Hill, Ivan Maillard, David H. Munn, Jonathan S. Serody, William J. Murphy, David Miklos, Corey S. Cutler, John Koreth, Joseph H. Antin, Robert J. Soiffer, Jerome Ritz, Carol Dahlberg, Andrew T. Miller, Bruce R. Blazar
Journal: Blood
Blood (2020) 135 (1): 28–40.
https://doi.org/10.1182/blood.2019000032
Published: 2020
Includes: Supplemental data
Journal Articles

Preclinical Characterization of an ANTI-CD38/CD3 T CELL-Redirecting Bispecific Antibody

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Xiao He, PhD, Yanliang Zhang, PhD, Yun Wei Lai, MSc, Stephanie Baguley, MSc, Yan Li, PhD, Xia Cao, MSc, Ying Yan, PhD, Ken Takeshita, MD, Jerome B. Zeldis, MD PhD, Henry Ji, PhD, Gunnar F. Kaufmann, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4463.
https://doi.org/10.1182/blood-2019-131540
Published: 2019
Journal Articles

Aberrant Cathepsin S Induces a Supportive Immune Microenvironment in Follicular Lymphoma

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Johannes Adrian Hildebrand, MSc, BSc, Deepak Bararia, Sebastian Stolz, Sarah Haebe, MD, Stefan Alig, Michael Bartoschek, Michael Boesl, Alessandro Pastore, Erik Gaitzsch, Michael Heide, Vindi Jurinovic, MSc, Monika Szczepanowski, Wolfram Klapper, Abner Louissaint, Jr., MD PhD, Christina Ludwig, Sebastian Bultmann, Heinrich Leonhardt, Sebastian Eustermann, Karl-Peter Hopfner, Wolfgang Hiddemann, MD PhD, Michael von Bergwelt, Christian Steidl, MD, Robert Kridel, MDMPH,PhD, David M Weinstock, Marc Schmidt-Supprian, Menyhárt B Sárosi, Verena Passerini, Josef Mautner, Oliver Weigert
Journal: Blood
Blood (2019) 134 (Supplement_1): 657.
https://doi.org/10.1182/blood-2019-122663
Published: 2019
Journal Articles

Transcriptomic Analysis of CD4+ T Cell Dysfunction during Gvhd: Evidence for Profound Reprograming of T Cell Signaling during Acute Gvhd That Is Controlled during CD28:CD80/86 Costimulation Blockade with Abatacept

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Benjamin Watkins, Yvonne Suessmuth, Kayla Betz, BS, Alison Yu, PhD, Brandi Bratrude, Muna Qayed, MD MSc, Kathryn Pellegrini, Steven Bosinger, Amelia Langston, MD, John T. Horan, MDMPH, Bruce R. Blazar, MD, Leslie Kean, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 596.
https://doi.org/10.1182/blood-2019-131955
Published: 2019
Journal Articles

Dissecting Heterogeneity of Tumor Cells and Their Microenvironment in Refractory Multiple Myeloma

Free
Stephan M Tirier, PhD, Jan-Philipp Mallm, PhD, Nicola Casiraghi, PhD, Hana Susak, PhD, Nicola Giesen, MD, Alexandra M Poos, PhD, Katharina Bauer, Anja Baumann, Lukas John, MD, Jing Xu, PhD, Lara Klett, MSc, Carsten Müller-Tidow, MD, Benedikt Brors, PhD, Hartmut Goldschmidt, MD, Niels Weinhold, PhD, Oliver Stegle, PhD, Karsten Rippe, PhD, Marc S. Raab, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 571.
https://doi.org/10.1182/blood-2019-128625
Published: 2019
Journal Articles

A Failure to Start: Aborted Activation of CAR T Cells in Chronic Lymphocytic Leukemia

Free
McKensie Collins, BS, Weimin Kong, PhD, Inyoung Jung, BS, Meng Wang, BS, Stefan M Lundh, BS, Carl H June, MD, J. Joseph Melenhorst, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 681.
https://doi.org/10.1182/blood-2019-122063
Published: 2019
Journal Articles

VISTA Is a Novel Regulator of Macrophage Biology

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Parth Shah, MD, Mohamed Eltanbouly, BSc, Nicole Smits, Aurelien Sarde, Randolph Noelle, Rodwell Mabaera, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2320.
https://doi.org/10.1182/blood-2019-131310
Published: 2019
Journal Articles

CD20-TCB, a Novel T-Cell-Engaging Bispecific Antibody, Induces T-Cell-Mediated Killing in Relapsed or Refractory Non-Hodgkin Lymphoma: Biomarker Results From a Phase I Dose-Escalation Trial

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Ann-Marie E Bröske, PhD, Ian James, PhD, Anton Belousov, PhD, Enrique Gomez, PhD, Marta Canamero, MD PhD, Chia-Huey Ooi, PhD, Nils Grabole, PhD, Sabine Wilson, PhD, Koorosh Korfi, PhD, Nicole A Kratochwil, PhD, Peter N Morcos, PharmD, Cristiano Ferlini, MD, Denise Thomas, MSc, Natalie Dimier, PhD, Tom Moore, MBChB, Marina Bacac, PhD, Martin Weisser, MD, Michael Dickinson, MBBS,FRACP,FRCPA
Journal: Blood
Blood (2019) 134 (Supplement_1): 5319.
https://doi.org/10.1182/blood-2019-123979
Published: 2019
Journal Articles

Lymphatic Control of the Tumor Immune Microenvironment

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Melody A. Swartz, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): SCI-46.
https://doi.org/10.1182/blood-2019-123389
Published: 2019
Journal Articles

Dynamic Immune Modulation Seen By Single Cell RNA-Sequencing of Serial Lymphoma Biopsies in Patients Undergoing in Situ Vaccination

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Tanaya Shree, MD PhD, Sarah Haebe, MD, Anuja Sathe, PhD, Grady Day, HoJoon Lee, PhD, Debra K. Czerwinski, BA, Susan Grimes, BSc, Hanlee Ji, MD, Ronald Levy, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1479.
https://doi.org/10.1182/blood-2019-131684
Published: 2019
Journal Articles

Malignant T-Cells and Normal Intratumoral T-Cells Have Similar Expression of Immune Checkpoint Molecules in Angioimmunoblastic T-Cell Lymphoma

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Joshua C Pritchett, MD, Zhi-Zhang Yang, MD, Hyojin Kim, PhD, Jose C Villasboas, MD, Andrew L. Feldman, MD, James R. Cerhan, MD PhD, Stephen M Ansell, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1517.
https://doi.org/10.1182/blood-2019-131145
Published: 2019
Journal Articles

In Vivo Efficacy of Anti-CD20-Interferon-Gamma Fusion Protein Against Syngeneic B Cell Lymphoma Is Mediated By Natural Killer Cells

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Alex Vasuthasawat, BS, MS, Reiko E Yamada, Kham R Trinh, Neiki Rokni, Sherie L Morrison, PhD, John M. Timmerman, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1575.
https://doi.org/10.1182/blood-2019-131890
Published: 2019
Journal Articles

Role of Vav1 Genomic Alterations in T-Cell Differentiation and Transformation in Peripheral T-Cell Lymphoma

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Jose Rodriguez Cortes, PhD, Anisha R. Cooke, Aidan Quinn, Ioan Filip, PhD, Juan Angel Patino, PhD, Raul Rabadan, PhD, Adolfo A. Ferrando, MD PhD, Teresa Palomero, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1482.
https://doi.org/10.1182/blood-2019-129438
Published: 2019
Journal Articles

Flotetuzumab (FLZ), an Investigational CD123 x CD3 Bispecific Dart® Protein-Induced Clustering of CD3+ T Cells and CD123+ AML Cells in Bone Marrow Biopsies Is Associated with Response to Treatment in Primary Refractory AML Patients

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John E. Godwin, MD, Carmen Ballesteros-Merino, PhD, Nikhil Lonberg, Shawn Jensen, PhD, Tarsem Moudgil, Carlo B Bifulco, MD, Jon Wigginton, MD, John Muth, MS, Jan K Davidson-Moncada, MD PhD, Bernard Fox, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1410.
https://doi.org/10.1182/blood-2019-128485
Published: 2019
Journal Articles

Blinatumomab-Induced T Cell Activation at Single Cell Transcriptome Resolution

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Hong Yin, MD PhD, Yi Huo, PhD, Zhen Sheng, PhD, Chi-Ming Li, PhD, Daniel C Ellwanger, PhD, Daniel Lu, PhD, Oliver Homann, PhD, Songli Wang, MD PhD, Ruibao Ren, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3886.
https://doi.org/10.1182/blood-2019-124636
Published: 2019
Journal Articles

Mesothelin Targeting Bites for Pediatric AML: In Vivo Efficacy and Specificity

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Anilkumar Gopalakrishnapillai, PhD, Colin Correnti, PhD, Anne Kisielewski, BS, Allison Kaeding, MD, Soheil Meshinchi, MD PhD, E. Anders Kolb, MD, Sonali Barwe, PhD MSc
Journal: Blood
Blood (2019) 134 (Supplement_1): 3925.
https://doi.org/10.1182/blood-2019-130941
Published: 2019