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Journal Articles

Hyperstable SGK1 steps out of AKT’s shadow

Franziska Gehringer, Alexey Ushmorov
Journal: Blood
Blood (2021) 138 (11): 917–918.
https://doi.org/10.1182/blood.2021012518
Published: 2021
Journal Articles

SGK1 mutations in DLBCL generate hyperstable protein neoisoforms that promote AKT independence

Brief Report
Jie Gao, Eirini Sidiropoulou, Ieuan Walker, Joanna A. Krupka, Karol Mizielinski, Zelvera Usheva, Shamith A. Samarajiwa, Daniel J. Hodson
Journal: Blood
Blood (2021) 138 (11): 959–964.
https://doi.org/10.1182/blood.2020010432
Published: 2021
Includes: Supplemental data
Journal Articles

Coding and noncoding drivers of mantle cell lymphoma identified through exome and genome sequencing

Prasath Pararajalingam, Krysta M. Coyle, Sarah E. Arthur, Nicole Thomas, Miguel Alcaide, Barbara Meissner, Merrill Boyle, Quratulain Qureshi, Bruno M. Grande, Christopher Rushton, Graham W. Slack, Andrew J. Mungall, Constantine S. Tam, Rishu Agarwal, Sarah-Jane Dawson, Georg Lenz, Sriram Balasubramanian, Randy D. Gascoyne, Christian Steidl, Joseph Connors, Diego Villa, Timothy E. Audas, Marco A. Marra, Nathalie A. Johnson, David W. Scott, Ryan D. Morin
Journal: Blood
Blood (2020) 136 (5): 572–584.
https://doi.org/10.1182/blood.2019002385
Published: 2020
Includes: Supplemental data
Journal Articles

Platelet RNA Splicing Profiles Can Distinguish IgM MGUS Patients from Healthy Individuals

Mick J.M. Van Eijs, MSc, Nicolette C. Notermans, MD PhD, Tom Würdinger, PhD, Monique C. Minnema, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3771.
https://doi.org/10.1182/blood-2019-124325
Published: 2019
Journal Articles

C/EBPβ Isoforms Regulate Proliferation and Differentiation of Regenerating Hematopoietic Stem/Progenitor Cells

Atsushi Sato, MD, Asumi Yokota, PhD, Yoshihiro Hayashi, MD PhD, Naoka Kamio, MD, Satoshi Sagai, Taira Maekawa, MD PhD, Hideyo Hirai, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3713.
https://doi.org/10.1182/blood-2019-128026
Published: 2019
Journal Articles

Epigenetic Activation of the pH Regulator MCT4 in Acute Myeloid Leukemia Exploits a Fundamental Metabolic Process of Enhancing Cell Growth through Proton Shifting

Cheuk-Him Man, David T. Scadden, MD, Francois Mercier, MD FRCPC, Nian Liu, Wentao Dong, Gregory Stephanopoulos, PhD, Li Jiang, PhD, Yookyung Jung, PhD, Charles Lin, PhD, Anskar Y.-H. Leung, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3765.
https://doi.org/10.1182/blood-2019-123604
Published: 2019
Journal Articles

Class I PI3K Is Required for HSC Differentiation

Kristina Ames, PhD, Imit Kaur, PhD, Meng Tong, Shayda Hemmati, PhD, Ellen Tein, Shira Glushakow-Smith, Lindsay Gurska, Kira Gritsman, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2461.
https://doi.org/10.1182/blood-2019-123823
Published: 2019
Journal Articles

iPLA2β Contributes to Activation of Human and Mouse Platelets Via ITAM Receptors Fcγ RIIA and GPVI

Shaji Abraham, PhD, Pravin Patel, BA, Ulhas P. Naik, PhD, Steven Edward McKenzie, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2339.
https://doi.org/10.1182/blood-2019-128426
Published: 2019
Journal Articles

Phenotypic Corrections of Ex Vivo Erythrocytes Derived from Chronic Hemolytic Anemia Patients Due to Krϋppel-like Factor 1 ( KLF-1 ) Mutations By AG-348: A Novel Synthetic Pyruvate Kinase Activator

Thidarat Suksangpleng, PhD, Kalaya Tachavanich, M.Sc., Suchada Riolueang, MSc, Supachai Ekwattanakit, PhDMD, Vip Viprakasit, MD DPhil
Journal: Blood
Blood (2019) 134 (Supplement_1): 2220.
https://doi.org/10.1182/blood-2019-131720
Published: 2019
Journal Articles

Rive-CLL: Phase 1 Trial of Rituximab, Idelalisib, and Venetoclax in Patients with Relapsed or Refractory Chronic Lymphocytic Leukemia

John McKay, DO, Taha Al-Juhaishi, MD, Lai Guanhua, MD PhD, Maciej Kmieciak, PhD, Roy Sabo, PhD, Ariel Sindel, DO, Victor Yazbeck, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5482.
https://doi.org/10.1182/blood-2019-126335
Published: 2019
Journal Articles

Idelalisib for Relapsed/Refractory Follicular Lymphoma: Retrospective Study from Spanish Lymphoma Group Geltamo (GELT-IDE-2018-02)

Juan-Manuel Sancho, MD PhD, Olga García, Pablo Mozas, Santiago Mercadal, MD, Eva Donato, MD, Ana Muntañola Prat, MD, Javier Lopez Jimenez, MD, Pascual Fernandez Abellan, PhD, Jose-Angel Hernandez, MD, Maria J. Rodriguez-Salazar, MD, Samuel Romero, MD, Ana Marin Niebla, PhD, Angel Ramirez Payer, Raul Cordoba, MD PhD, Jose Luis Bello, MD, Beatriz Cuevas, MD, Itziar Oiartzabal, MD, Alejandro Martín, MD PhD, Jose Javier Sanchez Blanco, Nicholas Kelleher, MD, Ana Lafuente, MD, Marc Sorigué, MD, López Guillermo Armando, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5249.
https://doi.org/10.1182/blood-2019-125921
Published: 2019
Journal Articles

Risk of Serious Adverse Events, Infection and Sepsis in Patients with Relapsed and Refractory Chronic Lymphocytic Leukemia/ Small Lymphocytic Lymphoma Treated with Idelalisib

Jonathan Kopel, BS, Sriman Swarup, MDMBBS, Anita Sultan, MD, Lukman Tijani, MD, Ei Moe Phyu, MD, Myint Aung Win, MDMBBS, Thura Win Htut, MBBS, MRCP, Ye Aung, Akshar Dash, Myat Min Han, MD, Yin Mon Myat, MD, Donald P. Quick, MD, Nicholas D'Cunha, MD, Kyaw Zin Thein, MDMBBS
Journal: Blood
Blood (2019) 134 (Supplement_1): 5489.
https://doi.org/10.1182/blood-2019-123179
Published: 2019
Journal Articles

Quantitative Investigation of Pharmacologically Modulated Signaling and Efficacy in ABC DLBCL Using a Systems Pharmacology Model

Kosinsky Yuri, PhD, Lulu Chu, PhD, Millie Shah, PhD, Karthick Vishwanathan, PhD, Connie Larsson, PhD, Andrew Bloecher, PhD, Brandon Willis, PhD, Hannah Dry, BSc, Kirill Peskov, PhD, Joseph Ware, PhD, Andrew Mortlock, PhD, Gabriel Helmlinger, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5304.
https://doi.org/10.1182/blood-2019-130879
Published: 2019
Journal Articles

Ywhae/14-3-3ε Expression Promotes Translation Initiation and Protein Synthesis in Multiple Myeloma Regulating Proteasome Load and Contributing to Proteasome Inhibitor Sensitivity/Resistance

Yan Xu, MD, Matthew Ho, PhD, Mehmet Kemal Samur, PhD, Kenneth Wen, Shuhui Deng, MD, Lanting Liu, MD, Tengteng Yu, MD PhD, Zuzana Chyra, PhD, Sanika Derebail, Kenneth C. Anderson, MD, Lugui Qiu, MD PhD, Mariateresa Fulciniti, PhD, Nikhil C. Munshi, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5539.
https://doi.org/10.1182/blood-2019-130902
Published: 2019
Journal Articles

High-Throughput RNA Sequencing Analysis Reveals Distinct Molecular Signature in NRAS and PTPN11 JMML Patients

Pier Paolo Leoncini, PhD, Alessandro Domenico Silvestris, PhD, Patrizia Vitullo, PhD, Marco Zecca, MD, Christian Flotho, MD PhD, Charlotte M. Niemeyer, MD, Angela Gallo, PhD, Alice Bertaina, MD PhD, Franco Locatelli, MD PhD, Pietro Merli, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4229.
https://doi.org/10.1182/blood-2019-129965
Published: 2019
Journal Articles

FBXO11 Is a Candidate Tumor Suppressor in the Transformation of MDS to Secondary AML

Michael Schieber, MD, John D. Crispino, PhD MBA
Journal: Blood
Blood (2019) 134 (Supplement_1): 4217.
https://doi.org/10.1182/blood-2019-124007
Published: 2019
Journal Articles

Phase 1 Trial of K0706, a Novel Oral BCR-ABL1 Tyrosine Kinase Inhibitor (TKI): In Patients with Chronic Myelogenous Leukemia (CML) and Phildelphia Positive Acute Lymphoblastic Leukemia (Ph+ ALL) Failing ≥ 3 Prior TKI Therapies: Initial Safety and Efficacy

Jorge E. Cortes, MD, Dong-Wook Kim, Franck E Nicolini, MD PhD, Tapan Saikia, MD, Aude Charbonnier, Jane F. Apperley, MD FRCP, FRCPath, MB, Krishna Rathnam, Michael W. Deininger, Hugues De Lavallade, Navin Khattry, MD DM MDcal Oncology, Andrew Whiteley, MD, Michael J. Mauro, MD, Gregor Verhoef, MD PhD, Carlo Gambacorti-Passerini, MD, Alessandro Lucchesi, MD, Shashikant Apte, MD FRCPA, Granacher Nikki, Siu-Long Yao, MD, Mudgal Kothekar, MD, Jayasree Sreenivasan, Msc, Bimba HV, MD, Geetanjali Chimote, MBBS, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4158.
https://doi.org/10.1182/blood-2019-129751
Published: 2019
Journal Articles

Bromodomain and Extra Terminal Domain (BET) Inhibitors Sensitize Chronic Myelomonocytic Leukemia (CMML) to PIM Inhibition Via Downregulation of Mir-33a

Christopher Letson, BS, Alexis Vedder, BS, Ariel Quintana, PhD, Phillip Liu, PhD, Brett Reid, Maria E Balasis, Hannah Newman, BS, Traci Kruer, PhD, Luciana L Almada, PhD, Guolin Zhang, PhD, Martin Fernandez-Zapico, MD, Mrinal M Patnaik, MDMBBS, Jeffrey E. Lancet, MD, Rami S. Komrokji, MD, P.K. Epling-Burnette, PharmD, PhD, Alan F. List, MD, Eric B. Haura, MD, Gary W. Reuther, Thomas A. Sellers, PhD, Holly K. Koblish, PhD, Eric Padron, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4220.
https://doi.org/10.1182/blood-2019-128165
Published: 2019
Journal Articles

Altered Iron Parameters and Hepcidin Levels in a General Population: Lessons from the CHRIS Study

Fabiana Busti, MD PhD, Annalisa Castagna, B.S., PhD, Giacomo Marchi, MD, Oliviero Olivieri, MD, Peter Pramstaller, MD, Domenico Girelli, MD, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2239.
https://doi.org/10.1182/blood-2019-127098
Published: 2019
Journal Articles

PI3Kδ Inhibition Enhances Sensitivity of Primary High-Risk Childhood B-Cell Acute Lymphoblastic Leukemia Cells to Glucocorticoid Chemotherapy

Jessica A.O. Zimmerman, MD, Mimi Fang, Arunkumar Modi, MBBS, MPH, Adam Dupuy, PhD, Sarah K. Tasian, MD, Miles A. Pufall, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2572.
https://doi.org/10.1182/blood-2019-129205
Published: 2019