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Journal Articles

The metabolic enzyme pyruvate kinase M2 regulates platelet function and arterial thrombosis

Manasa K. Nayak, Madankumar Ghatge, Gagan D. Flora, Nirav Dhanesha, Manish Jain, Kathleen R. Markan, Matthew J. Potthoff, Steven R. Lentz, Anil K. Chauhan

Blood (2021) 137 (12): 1658–1668.

https://doi.org/10.1182/blood.2020007140

Published: 2021

Includes: Supplemental data

Journal Articles

Structure of the platelet glycoprotein Ib receptor in complex with a novel antithrombotic agent

Jing Wang, Yongxiang Gao, Lan Chen, Yugang Guo, Siyi Hu, Liansheng Cheng, Weihua Xiao, Jiyuan Ke, Zhongliang Zhu, Liwen Niu

Blood (2021) 137 (6): 844–847.

https://doi.org/10.1182/blood.2020008028

Published: 2021

Includes: Supplemental data

Journal Articles

Megakaryopoiesis and Platelet-Innate Immune Cell Interactions Are Developmentally Regulated

Kathleen E. McGrath, PhD, Catherman C Seana, MS, Zachary T Hilt, MS, Katherine H Fegan, MS, Paul D. Kingsley, PhD, Leah A Vitt, BS, Massiel Chavez Stolla, PhD, Craig N. Morrell, PhD, James Palis, MD

Blood (2019) 134 (Supplement_1): 2470.

https://doi.org/10.1182/blood-2019-131039

Published: 2019

Journal Articles

Platelet Function in Paroxysmal Nocturnal Haemoglobinuria

Fathima Mohiyaddin Ayyalil, MBBS, FRACP,FRCPA, Samantha J Montague, BSc, PhD, Sarah Hicks, Amandeep Kaur, PhD, Anila Jahangiri, Nalini Pati, MBBS,FRACP,FRCPA, DCH, MD DNB, Philip Crispin, MBBS, FRACP, FRCPA, Yujie Zheng, Xu Tienan, Lucy Coupland, PhDBSc,RN, Woei Ming Lee, James D'Rozario, MBBS, FRACP, FRCPA, Elizabeth E. Gardiner, PhD

Blood (2019) 134 (Supplement_1): 4884.

https://doi.org/10.1182/blood-2019-130291

Published: 2019

Journal Articles

In Vitro Functionality of hiPSC Derived PLT+: The Utility of Microfluidic Assays in Determining Potency

Marcus Lehmann, PhD, Annie K Burton, Savannah G Szemethy, Jorge Valdez, PhD, Jonathan N. Thon, PhD

Blood (2019) 134 (Supplement_1): 1168.

https://doi.org/10.1182/blood-2019-131896

Published: 2019

Journal Articles

Targeting Metabolic Enzyme Pyruvate Kinase M2: A Novel Strategy to Inhibit Platelet Function and Arterial Thrombosis

Manasa K Nayak, PhD, Madankumar Ghatge, PhD, Nirav Dhanesha, PhD, Gagan D Flora, PhD, Manish Jain, PhD, Omar Rodriguez, MD BS, Kathleen Markan, PhD, Mathhhew Potthoff, PhD, Steven R. Lentz, MD PhD, Anil K Chauhan, PhD

Blood (2019) 134 (Supplement_1): 1056.

https://doi.org/10.1182/blood-2019-129027

Published: 2019

Journal Articles

M6PR-Specific Targeting of Lysosomal Heparanase Regulates Platelet Hemostatic Function in Mice

Nathan Eaton, BS, Caleb Drew, BS, Theresa A. Dlugi, PhD, Karin M. Hoffmeister, MD, Hervé Falet, PhD

Blood (2019) 134 (Supplement_1): 1059.

https://doi.org/10.1182/blood-2019-129075

Published: 2019

Journal Articles

Tyrosine Kinase Inhibitors (TKIs) Targeting Syk and BTK Signaling Differentially Affect PI3K Signalosome Organization and Platelet Function

Tony Zheng, Elizabeth R Lofurno, Sarah Elgamal, Alexander R Melrose, Jiaqing Pang, Joseph J Shatzel, MD, Owen J T McCarty, PhD, Joseph Aslan, PhD

Blood (2019) 134 (Supplement_1): 2074.

https://doi.org/10.1182/blood-2019-129066

Published: 2019

Journal Articles

Regulation of Platelet Function By Adenosine Receptors

Daniel N. Darlington, PhD, Xiaowu Wu, MD MSc, Kevin L. Chang, BS, James Bynum, PhD, Andrew P. Cap, MD PhD

Blood (2019) 134 (Supplement_1): 2348.

https://doi.org/10.1182/blood-2019-131129

Published: 2019

Journal Articles

Blood group alters platelet binding kinetics to von Willebrand factor and consequently platelet function

Eimear Dunne, Qin M. Qi, Eric S. Shaqfeh, Jamie M. O’Sullivan, Ingmar Schoen, Antonio J. Ricco, James S. O’Donnell, Dermot Kenny

Blood (2019) 133 (12): 1371–1377.

https://doi.org/10.1182/blood-2018-06-855528

Published: 2019

Includes: Multimedia, Supplemental data

Journal Articles

The transmembrane protein disulfide isomerase TMX1 negatively regulates platelet responses

Zhenzhen Zhao, Yi Wu, Junsong Zhou, Fengwu Chen, Aizhen Yang, David W. Essex

Blood (2019) 133 (3): 246–251.

https://doi.org/10.1182/blood-2018-04-844480

Published: 2019

Includes: Supplemental data

Journal Articles

αIIb(R990W), a Gain-of Function Mutation of αIIbβ3, Knock-in Mice Show Moderately Impaired Thrombopoiesis

Keigo Akuta, Kazunobu Kiyomizu, MD, Hirokazu Kashiwagi, Shinji Kunishima, PhD, Fumiaki Banno, Koichi Kokame, Nobuko Nishiura, Hisashi Kato, MD PhD, Shigenori Honda, MD, Yuzuru Kanakura, MD PhD, Toshiyuki Miyata, Yoshiaki Tomiyama, MD

Blood (2018) 132 (Supplement 1): 3743.

https://doi.org/10.1182/blood-2018-99-115953

Published: 2018

Journal Articles

Chronic Lymphocytic Leukaemia Is Associated with a Broad Platelet-Function Defect Which Is Exacerbated By Ibrutinib and Acalabrutinib

Scott R McGregor, BPharm, Grace Gilmore, Elizabeth E. Gardiner, PhD, Sarah Hicks, Shilpa Rakesh, Jim Tiao, Ross Baker, MBBS, FRACP, FRCPA, BSc

Blood (2018) 132 (Supplement 1): 3756.

https://doi.org/10.1182/blood-2018-99-120234

Published: 2018

Journal Articles

Comparing a New Bovine Source Heparin to the Clinically Used Porcine Heparin for Platelet Function Effects and Heparin-Induced Thrombocytopenia Potential

Michelle Sung, BS, Jeanine Walenga, PhD, Walter Jeske, PhD, Omer Iqbal, MD, Mamdouh Bakhos, MD

Blood (2018) 132 (Supplement 1): 2540.

https://doi.org/10.1182/blood-2018-99-118781

Published: 2018

Journal Articles

Poor Platelet Function on Sonoclot Signature Is Associated with High Incidence of Bleeding in Severe Immune Thrombocytopenia

Kundan Mishra, MD MBBS, MNAMS, Aditya Jandial, MD MBBS, Rajeev Sandal, MD, Pradakshna Porchezhian, MBBS, Samson Charan, MBBS, Lad Deepesh Pravin Kumar, Gaurav Prakash, MD DM, Alka Khadwal, MD, R K Dhiman, MD DM, Neelam Varma, MD, Pankaj Malhotra, MD

Blood (2018) 132 (Supplement 1): 4991.

https://doi.org/10.1182/blood-2018-99-117086

Published: 2018

Journal Articles

Severely Impaired Platelet Function Due to a Novel Mutation of P2Y12 from a Human Subject with No History of Bleeding

John C Kostyak, PhD, Carol A Dangelmaier, BS, Benjamin R Mauri, BS, Akruti Patel, MSc, Satya P. Kunapuli, PhD

Blood (2018) 132 (Supplement 1): 1130.

https://doi.org/10.1182/blood-2018-99-113015

Published: 2018

Journal Articles

Two Novel Compound Heterozygous Pathogenic Variants in P2YR12 gene

Arnaud Dupuis, PhD, Doris Böckelmann, PhD, Patricia Laeuffer, Katharina Neubauer, PhD, Christian Gachet, MD PhD, Barbara Zieger

Blood (2018) 132 (Supplement 1): 1154.

https://doi.org/10.1182/blood-2018-99-112833

Published: 2018

Journal Articles

Flow Cytometric Analysis of Platelet Function in Patients on Antiplatelet Therapy and Suspected Thrombocytopathy

Dana Huskens, PhD, Mark Roest, PhD, Lisa Florin, Bas De Laat, MD, PhD, Katrien Devreese, PhD MD

Blood (2018) 132 (Supplement 1): 1161.

https://doi.org/10.1182/blood-2018-99-110295

Published: 2018

Journal Articles

Platelet Dysfunction and Cellular Microparticles May be Involved in the Hipercoagulable State Observed in Obstructive Sleep Apnea Syndrome

Ihosvany Fernandez-Bello, Raul Justo Sanz, Elena Monzón Manzano, Francisco García Río, PhD, Carolina Cubillos, PhD, Cristina Balbás-García, Teresa Álvarez-Roman, Mónica Martín, María Isabel Rivas Pollmar, Miguel A. Canales, Victor Jimenez-Yuste, Nora Butta, PhD

Blood (2018) 132 (Supplement 1): 5048.

https://doi.org/10.1182/blood-2018-99-116018

Published: 2018

Journal Articles

A mutation of the human EPHB2 gene leads to a major platelet functional defect

Blood (2018) 132 (19): 2067–2077.

https://doi.org/10.1182/blood-2018-04-845644

Published: 2018

Includes: Supplemental data

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The metabolic enzyme pyruvate kinase M2 regulates platelet function and arterial thrombosis

Structure of the platelet glycoprotein Ib receptor in complex with a novel antithrombotic agent

Megakaryopoiesis and Platelet-Innate Immune Cell Interactions Are Developmentally Regulated

Platelet Function in Paroxysmal Nocturnal Haemoglobinuria

In Vitro Functionality of hiPSC Derived PLT+: The Utility of Microfluidic Assays in Determining Potency

Targeting Metabolic Enzyme Pyruvate Kinase M2: A Novel Strategy to Inhibit Platelet Function and Arterial Thrombosis

M6PR-Specific Targeting of Lysosomal Heparanase Regulates Platelet Hemostatic Function in Mice

Tyrosine Kinase Inhibitors (TKIs) Targeting Syk and BTK Signaling Differentially Affect PI3K Signalosome Organization and Platelet Function

Regulation of Platelet Function By Adenosine Receptors

Blood group alters platelet binding kinetics to von Willebrand factor and consequently platelet function

The transmembrane protein disulfide isomerase TMX1 negatively regulates platelet responses

αIIb(R990W), a Gain-of Function Mutation of αIIbβ3, Knock-in Mice Show Moderately Impaired Thrombopoiesis

Chronic Lymphocytic Leukaemia Is Associated with a Broad Platelet-Function Defect Which Is Exacerbated By Ibrutinib and Acalabrutinib

Comparing a New Bovine Source Heparin to the Clinically Used Porcine Heparin for Platelet Function Effects and Heparin-Induced Thrombocytopenia Potential

Poor Platelet Function on Sonoclot Signature Is Associated with High Incidence of Bleeding in Severe Immune Thrombocytopenia

Severely Impaired Platelet Function Due to a Novel Mutation of P2Y12 from a Human Subject with No History of Bleeding

Two Novel Compound Heterozygous Pathogenic Variants in P2YR12 gene

Flow Cytometric Analysis of Platelet Function in Patients on Antiplatelet Therapy and Suspected Thrombocytopathy

Platelet Dysfunction and Cellular Microparticles May be Involved in the Hipercoagulable State Observed in Obstructive Sleep Apnea Syndrome

A mutation of the human EPHB2 gene leads to a major platelet functional defect

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