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Journal Articles

Targeting Activated Signaling Pathways for the Treatment of IKZF1 -Deleted B Lymphoblastic Leukemia

Rohit Gupta, BA, Jason H. Rogers, MS, Xin Long, PhD, Geraldo Medrano, BS, Jaime M. Reyes, BS, Michele Redell, MD PhD, Zachary T Ball, PhD, Margaret Goodell, PhD, Rachel E. Rau, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3789.
https://doi.org/10.1182/blood-2019-127209
Published: 2019
Journal Articles

Real World Outcomes of Adult B-Cell Acute Lymphocytic Leukemia Patients Treated with Blinatumomab

Talha Badar, MD, Aniko Szabo, PhD, Anjali S. Advani, MD, Martha Wadleigh, MD, Shukaib Arslan, MD, Muhammad Khan, Ibrahim Aldoss, MD, Caitlin Siebenaller, PharmD, Elizabeth Schultz, Mehrdad Hefazi, MD, Rory M Shallis, MD, Ilana Yurkiewicz, MD BS, Nikolai A. Podoltsev, MD PhD, Anand Ashwin Patel, MD, Emily K Curran, MD, Suresh Kumar Balasubramanian, MD, Jay Yang, MD, Ryan J. Mattison, MD, Madelyn Burkart, MD, Shira Dinner, Michaela Liedtke, MD, Mark Litzow, MD, Ehab L. Atallah, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3809.
https://doi.org/10.1182/blood-2019-125466
Published: 2019
Journal Articles

Phase II Study of Midostaurin + Chemotherapy in Pediatric Patients with Untreated, Newly Diagnosed, FLT3 -Mutated Acute Myeloid Leukemia (AML)

Dirk Reinhardt, MD, Christian Michel Zwaan, Albert Hoenekopp, Julie Niolat, Sophie Ifrah, Florence Noel-Baron, Franco Locatelli, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3835.
https://doi.org/10.1182/blood-2019-128043
Published: 2019
Journal Articles

Pegaspargase Can Safely be Administered in Adults Age 40 and Older with Acute Lymphoblastic Leukemia

Ryan J. Daley, PharmD, Sridevi Rajeeve, MD, Charlene C. Kabel, PharmD, Jeremy J. Pappacena, PharmD, BCOP, Sarah E. Stump, PharmD, BCPS, BCOP, Jessica A. Lavery, MS, Martin S. Tallman, MD, Mark B. Geyer, MD, Jae H. Park, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3816.
https://doi.org/10.1182/blood-2019-124727
Published: 2019
Journal Articles

The Impact of Smoking on Survival in Patients (Pts) with Newly Diagnosed Philadelphia Chromosome Positive (Ph+) Acute Lymphoblastic Leukemia (ALL) Treated with the Combination of Intensive Therapy with Tyrosine Kinase Inhibitor (TKI)

Koji Sasaki, MD, Josep-Maria Ribera, MD PhD, Mary Figueroa, BS, Farhad Ravandi, MD, Nicholas J. Short, MD, Guillermo Garcia-Manero, MD, Naval G. Daver, MD, Tapan M. Kadia, MD, Marina Y Konopleva, MD PhD, Nitin Jain, MD, Ghayas C. Issa, MD, Zeev E. Estrov, MD, Rebecca Garris, MSc, Rita Khouri, Patrice Nasnas, MD, Courtney D. DiNardo, MDMSc, Kiran Naqvi, MDMPH, Steven M. Kornblau, MD, Guillermo Montalban-Bravo, MD, Naveen Pemmaraju, MD, Jorge E. Cortes, MD, Susan M. O'Brien, MD, Joya Chandra, PhD, Hagop M. Kantarjian, MD, Elias Jabbour, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3815.
https://doi.org/10.1182/blood-2019-129396
Published: 2019
Journal Articles

Blinatumomab in Combination with Pembrolizumab Is Safe for Adults with Relapsed or Refractory B-Lineage Acute Lymphoblastic Leukemia: University of California Hematologic Malignancies Consortium Study 1504

Marc Schwartz, MD, Lloyd E. Damon, MD, Deepa Jeyakumar, MD, Caitlin L. Costello, MD, Dimitrios Tzachanis, MD PhD, Gary J. Schiller, MD, Jesika Reiner, MPH, Matthew J. Wieduwilt, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3880.
https://doi.org/10.1182/blood-2019-131061
Published: 2019
Journal Articles

A Multicenter Phase I Study Combining Venetoclax with Mini-Hyper-CVD in Older Adults with Untreated and Relapsed/Refractory Acute Lymphoblastic Leukemia

Nitin Jain, MD, Kristen E. Stevenson, MS, Eric S. Winer, MD, Jacqueline S Garcia, MD, Richard M. Stone, MD, Elias Jabbour, MD, Farhad Ravandi, MD, Jeremy M. Stewart, BA, Dean R Legg, BA, Hagop M. Kantarjian, MD, Donna S Neuberg, ScD, Anthony G. Letai, MD PhD, Marina Y Konopleva, MD PhD, Daniel J. DeAngelo, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3867.
https://doi.org/10.1182/blood-2019-129988
Published: 2019
Journal Articles

Lack of Benefit of Extended Vincristine and Dexamethasone Pulses during Maintenance Treatment of Childhood Acute Lymphoblastic Leukemia: A Multicenter Randomized Controlled Study of Chinese Children Cancer Group (CCCG)-ALL-2015

Xiaofan Zhu, Shuhong Shen, MD PhD, Jiaoyang Cai, PhD, Shaoyan Hu, MD PhD, Ju Gao, PhD, Hui Zhang, MD PhD, Yongjun Fang, PhD, Xiuli Ju, Xiaowen Zhai, MD PhD, Xuedong Wu, MD PhD, Changda Liang, MD PhD, Xin Tian, PhD, Qun Hu, MD PhD, Ningling Wang, PhD, Runming Jin, MD, Hui Jiang, PhD, Lirong SUN, PhD, Minghua Yang, MD, Kaili Pan, PhD, Chi Kong Li, MBBS,MD, Jun J. Yang, PhD, Cheng Cheng, PhD, JingYan Tang, MD, Ching-Hon Pui, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2576.
https://doi.org/10.1182/blood-2019-128523
Published: 2019
Journal Articles

Major Deviations in the Delivery of Induction Chemotherapy Are Associated with an Increased Risk of Relapse in Acute Lymphoblastic Leukaemia: Results from UKALL2003

Rachael E Hough, MD, Amy A Kirkwood, Sujith Samarasinghe, Clare J Rowntree, MBBS, PhD FRCP, FRCPath, Nicholas John Goulden, MD PhD MRCPath, Ajay Vora
Journal: Blood
Blood (2019) 134 (Supplement_1): 2579.
https://doi.org/10.1182/blood-2019-127223
Published: 2019
Journal Articles

Health Insurance Status Impacts Rates of Overall Survival in Philadelphia-Positive Acute Lymphoblastic Leukemia

Jeremy Chang, MD, Sherry Zhang, MD, Mojtaba Akhtari, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2581.
https://doi.org/10.1182/blood-2019-123738
Published: 2019
Journal Articles

Treatment of Adults with Relapsed/Refractory Philadelphia Chromosome Negative Acute Lymphoblastic Leukemia with Blinatumomab in a Real-World Setting: Results from the Neuf Study

Nicolas Boissel, MD PhD, Josep-Maria Ribera, MD PhD, Sabina Chiaretti, MD PhD, Alessandro Rambaldi, MD, Renato Bassan, MD, Cristina Papayannidis, Naufil Alam, MSc, Alessandra Brescianini, PharmD, Isabella Pezzani, PharmD, Georg Kreuzbauer, MD, Robin Foà, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2627.
https://doi.org/10.1182/blood-2019-122917
Published: 2019
Journal Articles

New Paradigms for the Mechanisms of Thrombopoietin Receptor Activation and Dysregulation By the JAK2 V617F Mutation

Stephan Wilmes, PhD, Maximillian Hafer, BSc, Tess A Stanly, Ignacio Moraga, PhD, Joni Vuorio, PhD, Chetan Poojari, PhD, Vivek Sharma, PhD, Sara Löchte, PhD, Katiuska Pulgar Prieto, BSc, Julie A Tucker, PhD, Stevan R Hubbard, PhD, K.Christopher Garcia, PhD, Ilpo Vattulainen, PhD, Ian Hitchcock, PhD, Jacob Piehler, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2962.
https://doi.org/10.1182/blood-2019-129234
Published: 2019
Journal Articles

Effectiveness of Bosutinib in Chronic Myeloid Leukemia (CML) Who Have Received Multi Tyrosine Kinase Inhibitors (TKIs)

Jorge Cortes, MD, Hagop M. Kantarjian, MD, Guillaume Richard-Carpentier, MD, Gautam M. Borthakur, MD, Farhad Ravandi, MD, Kiran Naqvi, MDMPH, Koji Sasaki, MD, Tapan M. Kadia, MD, Srdan Verstovsek, MD PhD, Guillermo Garcia-Manero, MD, Courtney D. DiNardo, MDMSc, Naveen Pemmaraju, MD, Naval G. Daver, MD, Prithviraj Bose, MD, Sherry A. Pierce, BSN, BA, Samuel Dara, MBBS, Elias Jabbour, MD, Jorge E. Cortes, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2941.
https://doi.org/10.1182/blood-2019-121784
Published: 2019
Journal Articles

Allogeneic Hematopoietic Stem Cell Transplantation in Patients with Acute Lymphoblastic Leukemia and Karnofsky Performance Status Score Equal or Lower Than 80%. a Study from the Acute Leukemia Working Party (ALWP) of the European Society for Blood and Marrow Transplantation (EBMT)

Francesco Saraceni, Myriam Labopin, MD, Riitta Niittyvuopio, Gerard Socie, MD PhD, Nicolaus Kröger, Edouard Forcade, MD, Paul V Browne, MB,FRCPath, Péter Reményi, Jan J Cornelissen, MD PhD, Stephen Robinson, MBBS, PhD BSc, Ibrahim Yakoub-Agha, MD PhD, Thierry Lamy, PhD MD, Eolia Brissot, MD PhD, Bipin N. Savani, MD, Arnon Nagler, MD MSc, Mohamad Mohty, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3327.
https://doi.org/10.1182/blood-2019-127810
Published: 2019
Journal Articles

Phase I Study of Escalating Doses of Carfilzomib with Hyper-CVAD in Patients with Newly Diagnosed Acute Lymphoblastic Leukemia/Lymphoma

Samantha C Fisch, BS, Brian A Jonas, MD PhD, Joseph Tuscano, MD, Aaron Seth Rosenberg, MD, Rasmus T Hoeg, MD, Mehrdad Abedi, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3884.
https://doi.org/10.1182/blood-2019-121991
Published: 2019
Journal Articles

The Optimal Treatment Strategy for Adult Patients with Philadelphia Chromosome-Negative Acute Lymphoblastic Leukemia in First Complete Remission in the Era of High-Intensity Chemotherapy

Shinichi Kako, MD, Fumihiko Hayakawa, MD, PhD, Kiyotoshi Imai, Junji Tanaka, MD PhD, Shuichi Mizuta, Satoshi Nishiwaki, MD PhD, Heiwa Kanamori, MD PhD, Noriko Doki, MD PhD, Naoyuki Uchida, MD PhD, Kazuhiro Ikegame, MD PhD, Takahiro Fukuda, Tatsuo Ichinohe, Shuichi Ota, Yoshinori Tanaka, MD, Tohru Murayama, MD PhD, Shingo Kurahashi, MD PhD, Toru Sakura, Noriko Usui, MD PhD, Shigeki Ohtake, MD PhD, Hitoshi Kiyoi, MD PhD, Itaru Matsumura, MD PhD, Yasushi Miyazaki, MD PhD, Yoshiko Atsuta, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4589.
https://doi.org/10.1182/blood-2019-126012
Published: 2019
Journal Articles

Targeted Treatment and Survival Following Relapse after Allogeneic Hematopoietic Cell Transplantation for Acute Leukemia and MDS in the Contemporary Era

Sanghee Hong, MD, Lisa Rybicki, MS, Donna Corrigan, Betty K. Hamilton, MD, Ronald Sobecks, MD, Matt Kalaycio, MD, Robert M. Dean, MD, Brian T. Hill, MD, Brad Pohlman, MD, Deepa Jagadeesh, MDMPH, Faiz Anwer, MD, Navneet S. Majhail, MD MS
Journal: Blood
Blood (2019) 134 (Supplement_1): 4567.
https://doi.org/10.1182/blood-2019-124533
Published: 2019
Journal Articles

Ramp-up Treatment Strategy in Philadelphia Positive Acute Lymphoblastic Leukemia Is Associated with Deep Molecular Remissions and Favorable Outcomes

Nabiel A. Mir, MD, Charles Bodine, MD, Denise Peker, MD, Kimo Bachiashvili, MD, Pankit Vachhani, MD, Luciano J. Costa, MD PhD, Harry P. Erba, MD PhD, Nikolaos Papadantonakis, MD PhD MSc
Journal: Blood
Blood (2019) 134 (Supplement_1): 5120.
https://doi.org/10.1182/blood-2019-128770
Published: 2019
Journal Articles

FLAG-IDA and Ponatinib in Patients with Blast Phase Chronic Myeloid Leukaemia: Results from the Phase I/II UK Trials Acceleration Programme Matchpoint Trial

Mhairi Copland, PhD MBBChir, FRCP, FRCPath, Daniel Slade, MSc, BSc (Hons), Jenny Byrne, MD PhD, Kristian Brock, MSc, BSc, Hugues De Lavallade, Charles Craddock, FRCP, FRCPath, Richard Clark, MBBS, MRCP, MRCPath, MD, Matthew Smith, MBBS, Rebecca Bishop, BSc, Dragana Milojkovic, MBBS, MD, Christina Yap, MSci, PhD CStat
Journal: Blood
Blood (2019) 134 (Supplement_1): 497.
https://doi.org/10.1182/blood-2019-125591
Published: 2019
Journal Articles

Successful Treatment of Refractory Acute Lymphoblastic Leukemia with Tisagenlecleucel in the Setting of Life-Threatening Infection

Keith J August, MDMS, Terrie Flatt, DO,MA, Erin Marie Hall, MD, Doug Myers, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5125.
https://doi.org/10.1182/blood-2019-130880
Published: 2019