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Journal Articles

Placental HTRA1 cleaves α 1 -antitrypsin to generate a NET-inhibitory peptide

Robert A. Campbell, Heather D. Campbell, J. Samuel Bircher, Claudia Valeria de Araujo, Frederik Denorme, Jacob L. Crandell, John L. Rustad, Josh Monts, Mark J. Cody, Yasuhiro Kosaka, Christian C. Yost

Blood (2021) 138 (11): 977–988.

https://doi.org/10.1182/blood.2020009021

Published: 2021

Includes: Supplemental data

Journal Articles

Structural characterization of a novel GPVI-nanobody complex reveals a biologically active domain-swapped GPVI dimer

Alexandre Slater, Ying Di, Joanne C. Clark, Natalie J. Jooss, Eleyna M. Martin, Fawaz Alenazy, Mark R. Thomas, Robert A. S. Ariëns, Andrew B. Herr, Natalie S. Poulter, Jonas Emsley, Steve P. Watson

Blood (2021) 137 (24): 3443–3453.

https://doi.org/10.1182/blood.2020009440

Published: 2021

Includes: Multimedia, Supplemental data

Journal Articles

Molecular determinants of the factor VIII/von Willebrand factor complex revealed by BIVV001 cryo-electron microscopy

James R. Fuller, Kevin E. Knockenhauer, Nina C. Leksa, Robert T. Peters, Joseph D. Batchelor

Blood (2021) 137 (21): 2970–2980.

https://doi.org/10.1182/blood.2020009197

Published: 2021

Includes: Multimedia, Supplemental data

Journal Articles

Resolving thromboinflammation

Stephen P. McAdoo, Neeraj Dhaun

Blood (2021) 137 (11): 1444–1446.

https://doi.org/10.1182/blood.2020010627

Published: 2021

Journal Articles

Structural, functional, and mechanistic insights uncover the fundamental role of orphan connexin-62 in platelets

Khaled A. Sahli, Gagan D. Flora, Parvathy Sasikumar, Ali H. Maghrabi, Lisa-Marie Holbrook, Sarah K. AlOuda, Amro Elgheznawy, Tanya Sage, Alexander R. Stainer, Recep Adiyaman, Mohammad AboHassan, Marilena Crescente, Neline Kriek, Sakthivel Vaiyapuri, Alexander P. Bye, Amanda J. Unsworth, Chris I. Jones, Liam J. McGuffin, Jonathan M. Gibbins

Blood (2021) 137 (6): 830–843.

https://doi.org/10.1182/blood.2019004575

Published: 2021

Includes: Supplemental data

Journal Articles

Structure of the platelet glycoprotein Ib receptor in complex with a novel antithrombotic agent

Jing Wang, Yongxiang Gao, Lan Chen, Yugang Guo, Siyi Hu, Liansheng Cheng, Weihua Xiao, Jiyuan Ke, Zhongliang Zhu, Liwen Niu

Blood (2021) 137 (6): 844–847.

https://doi.org/10.1182/blood.2020008028

Published: 2021

Includes: Supplemental data

Journal Articles

A minority of T cells recognizing tumor-associated antigens presented in self-HLA can provoke antitumor reactivity

Marthe C. J. Roex, Lois Hageman, Sabrina A. J. Veld, Esther van Egmond, Conny Hoogstraten, Christian Stemberger, Lothar Germeroth, Hermann Einsele, J. H. Frederik Falkenburg, Inge Jedema

Blood (2020) 136 (4): 455–467.

https://doi.org/10.1182/blood.2019004443

Published: 2020

Includes: Supplemental data

Journal Articles

The role of AGK in thrombocytopoiesis and possible therapeutic strategies

Haojie Jiang, Zhuo Yu, Nan Ding, Mina Yang, Lin Zhang, Xuemei Fan, Yuan Zhou, Qiang Zou, Jian Hou, Junke Zheng, Lei Zhang, Yanyan Xu, Junling Liu

Blood (2020) 136 (1): 119–129.

https://doi.org/10.1182/blood.2019003851

Published: 2020

Includes: Supplemental data

Journal Articles

HLA loci predisposing to immune TTP in Japanese: potential role of the shared ADAMTS13 peptide bound to different HLA-DR

Blood (2020) 135 (26): 2413–2419.

https://doi.org/10.1182/blood.2020005395

Published: 2020

Includes: Supplemental data

Journal Articles

BIVV001, a new class of factor VIII replacement for hemophilia A that is independent of von Willebrand factor in primates and mice

Blood (2020) 135 (17): 1484–1496.

https://doi.org/10.1182/blood.2019001292

Published: 2020

Includes: Supplemental data

Journal Articles

Targeted Mass Spectrometry-Based Serum M-Protein Monitoring for Early Relapse Detection

Zac McDonald, PhD, Mariya Liyasova, PhD, Paul Taylor, Xin Xu, Kathleen Gorospe, Chenyu Yao, Qixin Liu, Liqiang Yang, PhD, Bin Ma, PhD, Jesus Piza, MD, Donna E Reece, MD, Suzanne Trudel, MD

Blood (2019) 134 (Supplement_1): 4347.

https://doi.org/10.1182/blood-2019-130251

Published: 2019

Journal Articles

Characterization of Mechanisms of Acquired Venetoclax-Insensitivity in B-Cell Precursor Acute Lymphoblastic Leukemia

Alexandra Niedermayer, MSc, Stefanie Enzenmüller, PhD, Eugen Tausch, Stephan Stilgenbauer, MD, Felix Seyfried, MD, Klaus-Michael Debatin, MD, Lüder Hinrich Meyer, MD

Blood (2019) 134 (Supplement_1): 3954.

https://doi.org/10.1182/blood-2019-126582

Published: 2019

Journal Articles

A Core Proliferative Program Induced By B-Cell Receptor Stimulation in Chronic Lymphocytic Leukemia Cells

Cédric Schleiss, Raphael Carapito, PhD, Luc Mathieu Fornecker, MD PhD, Leslie Muller, Paul Nicodeme, Ouria Tahar, Angélique Pichot, BSc, Laurent Mauvieux, MD PhD, Raoul Herbrecht, MD, Myriam Maumy-Bertrand, Jean-Noel Freund, Christine Carapito, Seiamak Bahram, MD, Frederic Bertrand, Laurent Vallat, MD PhD

Blood (2019) 134 (Supplement_1): 3777.

https://doi.org/10.1182/blood-2019-126779

Published: 2019

Journal Articles

Enhancer Rewiring Dependent Switch from BCL2 to MCL1 Dependency Predicts NOTCH1 Inhibition Response in T-ALL

Valeriya Dimitrova, Huiyoung Yun, PhD, Sayalee Potdar, Alexandria Nicole Van Scoyk, BS, Shruti Bhatt, PhD, Praveen Anand, PhD, Monica S. Nair, Jake A. Kloeber, Antonis Kokkalis, PhD MSc, Julia Frede, PhD MPhil, Johannes M. Waldschmidt, MD, Anthony G. Letai, MD PhD, David M. Weinstock, MD, Jon C. Aster, MD PhD, Jens G. Lohr, MD PhD, Birgit Knoechel, MD PhD

Blood (2019) 134 (Supplement_1): 3948.

https://doi.org/10.1182/blood-2019-131148

Published: 2019

Journal Articles

Quantitative Proteomics in Diffuse Large B-Cell Lymphoma Patients Reveal Novel Overexpressed Proteins and Potentially Druggable Targets in the ABC Subtype

Susanne Bram Ednersson, MD, Mimmie Stern, MD, Henrik Fagman, Gunilla Enblad, Ulf-Henrik Mellqvist, MD PhD, Herman Nilsson-Ehle, MD PhD, Sverker Hasselblom, Per-Ola Andersson, MD PhD

Blood (2019) 134 (Supplement_1): 3967.

https://doi.org/10.1182/blood-2019-126387

Published: 2019

Journal Articles

Targeting Misfolded p53 and p53 Aggregation to Overcome Resistance to Apoptosis in Acute Myeloid Leukemia

Michael Andreeff, MD PhD, Jianfang Zeng, MD, Alice Soragni, PhD, Vivian Ruvolo, Bing Z Carter, PhD, Jo Ishizawa, MD PhD, Jared K. Burks, PhD, David Eisenberg, PhD

Blood (2019) 134 (Supplement_1): 3786.

https://doi.org/10.1182/blood-2019-130900

Published: 2019

Journal Articles

Latent Membrane Protein 1 Contributes to Deficient Cellular Immunity in NKTCL Patients

Xiaoyan Feng, Yue Song, Zhaoming Li, MD PhD, Xudong Zhang, Lugui Qiu, MD PhD, Mingzhi Zhang, MD PhD

Blood (2019) 134 (Supplement_1): 3969.

https://doi.org/10.1182/blood-2019-128622

Published: 2019

Journal Articles

Targeting BCL-XL By Protac DT2216 Effectively Eliminates Leukemia Cells in T-ALL Pre-Clinical Models

Qi Zhang, PhD, Sajid Khan, PhD, Xuan Zhang, Vinitha Mary Kuruvilla, MSc, Sanaz Ghotbaldini, Julia Wells, PhD, Natalia Baran, PhDMD, Tianyu Cai, PhD, Lina Han, PhD, Adolfo Ferrando, MD, PhD, Yong-Mi Kim, MD MPH, PhD, Guangrong Zheng, Daohong Zhou, Marina Y Konopleva, MD PhD

Blood (2019) 134 (Supplement_1): 3870.

https://doi.org/10.1182/blood-2019-124744

Published: 2019

Journal Articles

Improved Overall Survival Among Newly Diagnosed Aggressive Adult T-Cell Leukemia/Lymphoma Patients Treated with Mogamulizumab Plus EPOCH Compared to Mogamulizumab Plus Vcap-AMP-Vecp

Tatsuro Jo, MD PhD, Kaori Matsuzaka, Haruna Shioya, Hiroo Tominaga, Takahiro Sakai, Yohei Kaneko, Shizuka Hayashi, Masatoshi Matsuo, MD, PhD, Jun Taguchi, MD PhD, Kazuto Shigematsu, MD PhD

Blood (2019) 134 (Supplement_1): 4048.

https://doi.org/10.1182/blood-2019-123984

Published: 2019

Journal Articles

X-Ray Crystallographic and Single-Molecule Fluorescence Studies of Beta-2 Glycoprotein I Reveal an Alternative Mechanism of Autoantibody Recognition

William Planer, M.S., Zhiwei Chen, M.S., Mathivanan Chinnaraj, PhD, Xiaobing Zuo, PhD, Vittorio Pengo, MD, Paolo Macor, PhD, Francesco Tedesco, MD, Nicola Pozzi, PhD

Blood (2019) 134 (Supplement_1): 91.

https://doi.org/10.1182/blood-2019-122064

Published: 2019

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Placental HTRA1 cleaves α 1 -antitrypsin to generate a NET-inhibitory peptide

Structural characterization of a novel GPVI-nanobody complex reveals a biologically active domain-swapped GPVI dimer

Molecular determinants of the factor VIII/von Willebrand factor complex revealed by BIVV001 cryo-electron microscopy

Resolving thromboinflammation

Structural, functional, and mechanistic insights uncover the fundamental role of orphan connexin-62 in platelets

Structure of the platelet glycoprotein Ib receptor in complex with a novel antithrombotic agent

A minority of T cells recognizing tumor-associated antigens presented in self-HLA can provoke antitumor reactivity

The role of AGK in thrombocytopoiesis and possible therapeutic strategies

HLA loci predisposing to immune TTP in Japanese: potential role of the shared ADAMTS13 peptide bound to different HLA-DR

BIVV001, a new class of factor VIII replacement for hemophilia A that is independent of von Willebrand factor in primates and mice

Targeted Mass Spectrometry-Based Serum M-Protein Monitoring for Early Relapse Detection

Characterization of Mechanisms of Acquired Venetoclax-Insensitivity in B-Cell Precursor Acute Lymphoblastic Leukemia

A Core Proliferative Program Induced By B-Cell Receptor Stimulation in Chronic Lymphocytic Leukemia Cells

Enhancer Rewiring Dependent Switch from BCL2 to MCL1 Dependency Predicts NOTCH1 Inhibition Response in T-ALL

Quantitative Proteomics in Diffuse Large B-Cell Lymphoma Patients Reveal Novel Overexpressed Proteins and Potentially Druggable Targets in the ABC Subtype

Targeting Misfolded p53 and p53 Aggregation to Overcome Resistance to Apoptosis in Acute Myeloid Leukemia

Latent Membrane Protein 1 Contributes to Deficient Cellular Immunity in NKTCL Patients

Targeting BCL-XL By Protac DT2216 Effectively Eliminates Leukemia Cells in T-ALL Pre-Clinical Models

Improved Overall Survival Among Newly Diagnosed Aggressive Adult T-Cell Leukemia/Lymphoma Patients Treated with Mogamulizumab Plus EPOCH Compared to Mogamulizumab Plus Vcap-AMP-Vecp

X-Ray Crystallographic and Single-Molecule Fluorescence Studies of Beta-2 Glycoprotein I Reveal an Alternative Mechanism of Autoantibody Recognition

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American Society of Hematology

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