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Journal Articles

Hematopoietic Phf6 Deletion in Mice Causes HSC Depletion and Expansion of Myeloid Progenitors

Roman Verner, Gabrielle Ochoco, Patrick Somers, Cristian Taborda, Vikram R Paralkar, MD

Blood (2018) 132 (Supplement 1): 3829.

https://doi.org/10.1182/blood-2018-99-120041

Published: 2018

Journal Articles

DNA Damaging Agents Cause a Sub-Cellular Re-Localisation of Nucleophosmin in an npm1 Mutated Acute Myeloid Leukemia (AML) Cell Line and in Primary AML Cells Carrying an npm1 Mutation

Graham D. Bailey, PhD, Asma Akhtar, BSc, Nigel H. Russell, Claire Seedhouse, PhD

Blood (2017) 130 (Supplement 1): 1251.

https://doi.org/10.1182/blood.V130.Suppl_1.1251.1251

Published: 2017

Journal Articles

Clinical and Biological Role of Accumulation of the NPM-1 Splice Variant R2 in AML, MDS and sAML

Grazyna Stasiak, PhD, Malgorzata Zajac, PhD, Joanna Zaleska, Michal Kielbus, PhD, Jakub Czapinski, Andrzej Stepulak, MD PhD, Olga Jankowska-Lecka, PhD, Tomasz Gromek, MD PhD, Norbert Grzasko, MD PhD, Maria Soroka-Wojtaszko, MD PhD, Aneta Szudy-Szczyrek, MD, Bozena Sokolowska, MD PhD, Marek Hus, MD PhD, Lars Bullinger, MD PhD, Krzysztof Giannopoulos, MD PhD

Blood (2016) 128 (22): 2878.

https://doi.org/10.1182/blood.V128.22.2878.2878

Published: 2016

Journal Articles

Accumulation of the NPM-1 Splice Variant R2 Accompanies AML Development

Krzysztof Giannopoulos, MD PhD, Malgorzata Zajac, PhD, Olga Jankowska-Lecka, PhD, Joanna Zaleska, Joanna Purkot, Tomasz Gromek, MD, Maria Soroka-Wojtaszko, MD PhD, Aneta Szudy-Szczyrek, MD, Marek Hus, MD PhD, Lars Bullinger, MD

Blood (2015) 126 (23): 2590.

https://doi.org/10.1182/blood.V126.23.2590.2590

Published: 2015

Journal Articles

Lenalidomide Induced Degradation of Aiolos Disrupts RNA Polimerase I Activity and Ribosomal Biogenesis in Myeloma Cells

Ines Tagoug, PhD, Jiri Slaby, MD, Paola E. Neri, MD PhD, Justin Simms, Jackie Babich, Ranjan Maity, PhD, Li Ren, PhD, Howie Wu, Nizar J Bahlis, MD

Blood (2014) 124 (21): 3422.

https://doi.org/10.1182/blood.V124.21.3422.3422

Published: 2014

Journal Articles

Lenalidomide Induces A Ribosomal Stress Response In Multiple Myeloma (MM) Cells

Jiri Slaby, MD, Ines Tagoug, PhD, Paola Neri, MD, PhD, Justin Simms, Jacquelyn Babich, Kathy Gratton, Li Ren, PhD, Nizar J. Bahlis, MD

Blood (2013) 122 (21): 3161.

https://doi.org/10.1182/blood.V122.21.3161.3161

Published: 2013

Journal Articles

XPO1 Inhibition Disrupts Ribosomal Subunits Assembly and Induces Multiple Myeloma (MM) Cell Death

Ines Tagoug, PhD, Paola Neri, MD, PhD, Jiri Slaby, MD, Jacquelyn Babich, Justin Simms, Kathy Gratton, Li Ren, PhD, Nizar J. Bahlis, MD

Blood (2013) 122 (21): 3165.

https://doi.org/10.1182/blood.V122.21.3165.3165

Published: 2013

Journal Articles

The Nucleophosmin-1 Splice Variant Analysis Provides More Important Information On Prognosis Than NPM1 Mutational Status In Acute Myeloid Leukemia

Krzysztof Giannopoulos, MD, PhD, Malgorzata Zajac, Anna Dolnik, Stephany Correa, Konstanze Dohner, Richard F. Schlenk, MD, Lars Bullinger, MD, PhD

Blood (2013) 122 (21): 2563.

https://doi.org/10.1182/blood.V122.21.2563.2563

Published: 2013

Journal Articles

NPM-RAR Binds to Tradd and Impedes the Extrinsic Apoptotic Pathway

Robert L. Redner, MD, Anuja Chattopadhyay, Brian L. Hood, PhD, Thomas P. Conrads, PhD

Blood (2012) 120 (21): 5126.

https://doi.org/10.1182/blood.V120.21.5126.5126

Published: 2012

Journal Articles

Nuclear JAK2

Mark A. Dawson, Andrew J. Bannister, Lindsay Saunders, Omar-Abdel Wahab, Fan Liu, Stephen D. Nimer, Ross L. Levine, Berthold Göttgens, Tony Kouzarides, Anthony R. Green

Blood (2011) 118 (26): 6987–6988.

https://doi.org/10.1182/blood-2011-10-385278

Published: 2011

Journal Articles

Integrating Structural and Functional Studies Leads to a New Model of β-Globin Activation That Suggests Distinct Initiation and Maintenance States

M. A. Bender, MD, PhD, Davide Bau', PhD, Tobias Ragoczy, PhD, Rachel Byron, BS, Ye Zhan, BS, Bryan Lajoie, BS, Marc A. Marti-Renom, PhD, Job Dekker, PhD, Mark T. Groudine, MD, PhD

Blood (2011) 118 (21): 349.

https://doi.org/10.1182/blood.V118.21.349.349

Published: 2011

Journal Articles

Inhibition of RNA Polymerase I Transcription by CX-5461 As a Therapeutic Strategy for the Cancer-Specific Activation of p53 in MLL-Rearranged Acute Myeloid Leukemias

Nadine Hein, PhD, Megan J Bywater, PhD, Kim Stanley, BSc, Inge Verbrugge, PhD, Carlene Cullinane, PhD, Adele Baker, PhD, Hannes Zuber, PhD, Amy Rappaport, PhD, Denis Drygin, PhD, Nanni Huser, PhD, Josh Bliesath, PhD, David M Ryckman, PhD, William G Rice, PhD, Scott W Lowe, PhD, Ricky W Johnstone, PhD, Richard B Pearson, PhD, Grant A. McArthur, MD, PhD, FRACP, MBBS, Ross D Hannan, PhD

Blood (2011) 118 (21): 1548.

https://doi.org/10.1182/blood.V118.21.1548.1548

Published: 2011

Journal Articles

The Lamin B Receptor Provides Sterol Reductase Activities Critical to Neutrophil Development: Implications for Cholesterol Biosynthesis In Regulating Myelopoiesis

Gayathri Subramanian, MS, Pulkit Chaudhury, MS, Peter Gaines, PhD

Blood (2010) 116 (21): 389.

https://doi.org/10.1182/blood.V116.21.389.389

Published: 2010

Journal Articles

Microarray Analysis of Erythroid Gene Expression In Sickle Cell Anemia Patients Treated with Hydroxyurea.

Jonathan Michael Flanagan, Ph.D, Shirley Steward, Thad A Howard, MS, Nicole A Mortier, MHS, PA-C, Amy C Kimble, FNP, Banu Aygun, MD, Jane S Hankins, MD, MS, Geoffrey A. Neale, PhD, Russell E. Ware, MD, PhD

Blood (2010) 116 (21): 1623.

https://doi.org/10.1182/blood.V116.21.1623.1623

Published: 2010

Journal Articles

Impaired Ribosome Maturation In Human Cells Depleted of Shwachman-Diamond Syndrome Protein SBDS

Gulay Sezgin, MD, Abdallah Nihrane, PhD, Adrianna Henson, Max Wattenberg, Steven Ellis, PhD, Johnson M. Liu, MD

Blood (2010) 116 (21): 2242.

https://doi.org/10.1182/blood.V116.21.2242.2242

Published: 2010

Journal Articles

Role of Nucleophosmin Mutations in AML.

Kotaro Funato, MD, PhD, David W. Sternberg, MD, PhD

Blood (2008) 112 (11): sci-13.

https://doi.org/10.1182/blood.V112.11.sci-13.sci-13

Published: 2008

Journal Articles

Nucleophosmin (NPM) Has Increased Expression and Shuttling Activity in Chronic Lymphocytic Leukaemia without Somatic Hypermutation of the Immunoglubulin Gene (UM-CLL) and Is Linked to Ribosomal Proteins: A Possible Role for Increased Protein biosynthesis in the Adverse Outcome of UM-CLL.

Karen S Rees-Unwin, PhD, Robin Faragher, PhD, Claire V Hutchinson, FRCPath, Richard D Unwin, PhD, Julie Adams, PhD, Andrew Pettitt, PhD, FRCPath, Alison H Banham, PhD, Karen Pulford, PhD, John Burthem, PhD, FRCPath

Blood (2008) 112 (11): 2082.

https://doi.org/10.1182/blood.V112.11.2082.2082

Published: 2008

Journal Articles

Yeast Models of Diamond Blackfan Anemia and Shwachman Diamond Syndrome Differ in Their Effect on the Synthesis and Function of Ribosomal Subunits.

Steven R Ellis, PhD, Joseph B. Moore, IV, Johnson M. Liu, MD, Robert J. Arceci, MD, PhD, Jason E. Farrar, MD

Blood (2008) 112 (11): 2044.

https://doi.org/10.1182/blood.V112.11.2044.2044

Published: 2008

Journal Articles

A Novel Splicing Factor RBM25 in Erythroid Differentiation.

Anyu Zhou, PhD, Aeri Cho, MS, Shu-Ching Huang, PhD, Edward J. Benz, MD

Blood (2007) 110 (11): 1711.

https://doi.org/10.1182/blood.V110.11.1711.1711

Published: 2007

Journal Articles

Evaluation of the Expression of MDM2 & CD44v6 in Hodgkin’s Lymphoma.

Amr Farag El-Sebaaie, MSc, MD, Samya Ahmed Youssef, Msc, PHD, Osama Abed El-Fatah Hassan, Msc, PHD, MRCPath., Hala Adel Aggina, Msc, PHD, Nehal Saad Zafer, Msc, MD, Mahmoud Slah Abed El-Slam, Msc, MD

Blood (2007) 110 (11): 4389.

https://doi.org/10.1182/blood.V110.11.4389.4389

Published: 2007

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Hematopoietic Phf6 Deletion in Mice Causes HSC Depletion and Expansion of Myeloid Progenitors

DNA Damaging Agents Cause a Sub-Cellular Re-Localisation of Nucleophosmin in an npm1 Mutated Acute Myeloid Leukemia (AML) Cell Line and in Primary AML Cells Carrying an npm1 Mutation

Clinical and Biological Role of Accumulation of the NPM-1 Splice Variant R2 in AML, MDS and sAML

Accumulation of the NPM-1 Splice Variant R2 Accompanies AML Development

Lenalidomide Induced Degradation of Aiolos Disrupts RNA Polimerase I Activity and Ribosomal Biogenesis in Myeloma Cells

Lenalidomide Induces A Ribosomal Stress Response In Multiple Myeloma (MM) Cells

XPO1 Inhibition Disrupts Ribosomal Subunits Assembly and Induces Multiple Myeloma (MM) Cell Death

The Nucleophosmin-1 Splice Variant Analysis Provides More Important Information On Prognosis Than NPM1 Mutational Status In Acute Myeloid Leukemia

NPM-RAR Binds to Tradd and Impedes the Extrinsic Apoptotic Pathway

Nuclear JAK2

Integrating Structural and Functional Studies Leads to a New Model of β-Globin Activation That Suggests Distinct Initiation and Maintenance States

Inhibition of RNA Polymerase I Transcription by CX-5461 As a Therapeutic Strategy for the Cancer-Specific Activation of p53 in MLL-Rearranged Acute Myeloid Leukemias

The Lamin B Receptor Provides Sterol Reductase Activities Critical to Neutrophil Development: Implications for Cholesterol Biosynthesis In Regulating Myelopoiesis

Microarray Analysis of Erythroid Gene Expression In Sickle Cell Anemia Patients Treated with Hydroxyurea.

Impaired Ribosome Maturation In Human Cells Depleted of Shwachman-Diamond Syndrome Protein SBDS

Role of Nucleophosmin Mutations in AML.

Nucleophosmin (NPM) Has Increased Expression and Shuttling Activity in Chronic Lymphocytic Leukaemia without Somatic Hypermutation of the Immunoglubulin Gene (UM-CLL) and Is Linked to Ribosomal Proteins: A Possible Role for Increased Protein biosynthesis in the Adverse Outcome of UM-CLL.

Yeast Models of Diamond Blackfan Anemia and Shwachman Diamond Syndrome Differ in Their Effect on the Synthesis and Function of Ribosomal Subunits.

A Novel Splicing Factor RBM25 in Erythroid Differentiation.

Evaluation of the Expression of MDM2 & CD44v6 in Hodgkin’s Lymphoma.

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