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Journal Articles

Reduced Number and Function of Endothelial Progenitor Cells in Patients with Beta Thalassemia Major

Galia Spectre, Pinhas Stark, MD, Arza Steimatzky, MD, Pia Raanani, MD, Dorit Lev, PhD, Ran Kornowski, MD, Idit Pazgal, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2247.
https://doi.org/10.1182/blood-2019-129851
Published: 2019
Journal Articles

Establishment of a Spontaneous Stromal Microenvironment from Cord Blood Supports Human Dynamic Erythropoietic Temporal Maturation in Long-Term Serum- and Cytokine-Free 3D Cultures and Reveals a Distinct CD44 hi Population

Susana Brito Dos Santos, MSc PhD, Athanasios Mantalaris, PhD, Nicki Panoskaltsis, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2219.
https://doi.org/10.1182/blood-2019-131085
Published: 2019
Journal Articles

Durable and Robust Fetal Globin Induction without Anemia in Rhesus Monkeys Following Autologous Hematopoietic Stem Cell Transplant with BCL11A Erythroid Enhancer Editing

Selami Demirci, PhD, Jing Zeng, MD, Yuxuan Wu, PhD, Naoya Uchida, MD, Jackson Gamer, Morgan Yapundich, Claire Drysdale, Aylin C. Bonifacino, Allen E. Krouse, Nathaniel S. Linde, Robert E. Donahue, VMD, Anne H. Shen, Juan J. Haro-Mora, PhD, Alexis Leonard, MD, Tina Nassehi, Kevin Luk, Scot A. Wolfe, Cicera R. Lazzarotto, Shengdar Q. Tsai, PhD, Mitchell J. Weiss, MD, PhD, Daniel E. Bauer, MD PhD, John F. Tisdale, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4632.
https://doi.org/10.1182/blood-2019-129394
Published: 2019
Journal Articles

A Feasibility and Safety Study of a New CD19-Directed Fast CAR-T Therapy for Refractory and Relapsed B Cell Acute Lymphoblastic Leukemia

Junfang Yang, MD, Jiaping He, Xian Zhang, MD, Zhenguang Wang, Yongliang Zhang, Songbai Cai, Zhe Sun, Xun Ye, Yan He, Lianjun Shen, MD PhD, Jiujiang He, Gailing Zhang, MD, Dan Song, Min Zhang, Xiaona Hu, Jingjing Li, Shulian Xia, Li Xu, Wei Cao, Peihua Lu
Journal: Blood
Blood (2019) 134 (Supplement_1): 825.
https://doi.org/10.1182/blood-2019-121751
Published: 2019
Journal Articles

Patterns of Sensitivity Exhibited By Venetoclax-Inclusive Drug Combinations in Acute Myeloid Leukemia

Stephen E Kurtz, PhD, Christopher A. Eide, Andy Kaempf, MS, Nicola Long, Anupriya Agarwal, PhD, Cristina E. Tognon, Motomi Mori, PhD, Brian J. Druker, Jeffrey W. Tyner
Journal: Blood
Blood (2019) 134 (Supplement_1): 878.
https://doi.org/10.1182/blood-2019-126020
Published: 2019
Journal Articles

Expansion of Prior Existing TP53 Mutated Clones in Polycythemia Vera Patients Treated with Idasanutlin

Bridget Marcellino, MD PhD, Bruno Cassinat, PharmD, PhD, Noushin Farnoud, PhD, Min Lu, PhD, Emmanuelle Verger, PhD, Erin McGovern, BA, Minal A Patel, MPH, Heidi E. Kosiorek, MS, Meenakshi Mehrotra, PhD, Jane Houldsworth, PhD, Amylou C. Dueck, PhD, Michael Rossi, PhD, Jean-Jacques Kiladjian, MD PhD, Raajit K. Rampal, MD PhD, John Mascarenhas, MD, Ronald Hoffman, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 838.
https://doi.org/10.1182/blood-2019-128342
Published: 2019
Journal Articles

Single-Cell RNA Sequencing Reveals Distinct Hematopoietic Stem Cell Hierarchies in MDS

Irene Ganan-Gomez, PhD, Hui Yang, PhDMD, Feiyang Ma, Bs, Matteo Pellegrini, PhD, Karen Clise-Dwyer, PhD, Guillermo Garcia-Manero, MD, Simona Colla, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 771.
https://doi.org/10.1182/blood-2019-128798
Published: 2019
Journal Articles

Results of a Phase 1 Trial of Gda-201, Nicotinamide-Expanded Allogeneic Natural Killer Cells (NAM-NK) in Patients with Refractory Non-Hodgkin Lymphoma (NHL) and Multiple Myeloma (MM)

Veronika Bachanova, MD PhD, David H. McKenna, MD, Xianghua Luo, PhD, Todd E. DeFor, MS, Fiona He, MD, Murali Janakiram, MD MS, Erica D. Warlick, MD, Rose Wangen, Zuzan Cayci, MD, Bartosz Grzywacz, MD, Guy Brachya, PhD, Tony Peled, MSc, Jeffrey S. Miller, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 777.
https://doi.org/10.1182/blood-2019-130476
Published: 2019
Journal Articles

CD19-Directed Fast CART Therapy for Relapsed/Refractory Acute Lymphoblastic Leukemia: From Bench to Bedside

Cheng Zhang, Jiaping He, Li Liu, Jishi Wang, PhD, Sanbin Wang, Ligen Liu, Lei Gao, Li Gao, Yao Liu, Peiyan Kong, Jia Liu, Yu Han, Yongliang Zhang, Zhe Sun, Xun Ye, Yan He, Lianjun Shen, MD PhD, Wei Cao, Xi Zhang
Journal: Blood
Blood (2019) 134 (Supplement_1): 1340.
https://doi.org/10.1182/blood-2019-128006
Published: 2019
Journal Articles

STAT3 Mutations and Anemia with Pure Red Cell Aplasia Are the Distinctive Features of T Cell Receptor Gamma Delta Type Large Granular Lymphocyte Leukemia

Taku Yamane, Toru Kawakami, MD, Nodoka Sekiguchi, MD PhD, Jun Kobayashi, Toshimitsu Ueki, MD, Hikaru Kobayashi, MD PhD, Sayaka Nishina, Kaoko Sakai, MD, Hitoshi Sakai, MD, Kazuo Oshimi, MD, Yumiko Higuchi, PhD, Hideyuki Nakazawa, MD PhD, Fumihiro Ishida, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1500.
https://doi.org/10.1182/blood-2019-123614
Published: 2019
Journal Articles

Selinexor in Combination with Induction and Consolidation Therapy in Older Adults with AML Is Highly Active

Timothy S. Pardee, MD PhD, Kris C Wood, PhD, Kevin H Lin, BS, Justine Rutter, PhD, Mariaelena Pierobon, MD, Emanuel Petricoin, PhD, Susan Lyerly, P.A.-C., Sarah Dralle, NP, Megan Manuel, NP, Leslie Renee Ellis, MD, Dianna S. Howard, MD, Rupali Bhave, MD, Bayard L Powell, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1388.
https://doi.org/10.1182/blood-2019-129413
Published: 2019
Journal Articles

Aberrant Responsiveness of Erythropoiesis to Iron Deficiency in Polycythemia Vera

Maria Feola, PhD, Daniel Moskop, Nada Terra, Young C. Park, Andrew Dunbar, MD, Ross L. Levine, MD, Ronald Hoffman, MD, Yelena Ginzburg, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 429.
https://doi.org/10.1182/blood-2019-131095
Published: 2019
Journal Articles

Results of a Clinical Trial of H3B-8800, a Splicing Modulator, in Patients with Myelodysplastic Syndromes (MDS), Acute Myeloid Leukemia (AML) or Chronic Myelomonocytic Leukemia (CMML)

David P. Steensma, MD, Martin Wermke, MD, Virginia M. Klimek, MD, Peter L Greenberg, MD, Patricia Font, Rami S. Komrokji, MD, Jay Yang, MD, Andrew M. Brunner, MD, Hetty E. Carraway, MD MBA, Lionel Ades, MD PhD, Aref Al-Kali, MD, Juan Manuel Alonso Dominguez, MD PhD MSc, Ana Alonso, MD, Catherine C. Coombs, MD, H. Joachim Deeg, MD, William B. Donnellan, MD, James M. Foran, MD, Guillermo Garcia-Manero, MD, Michael B. Maris, MD, Malgorzata McMasters, MD, Jean-Baptiste Micol, MD, Jaime Perez De Oteyza, MD PhD, Felicitas Thol, MD, Eunice S. Wang, MD, Justin M. Watts, MD, Silvia Buonamici, PhD, Amy Kim, MSPh PhD, Vikram Gourineni, MS, PharmD, Alyssa J Marino, Nathalie Rioux, MSc, PhD, Joanne Schindler, MD, Sherri Smith, MS, Huilan Yao, PhD, Xiaobin Yuan, Kun Yu, PhD, Uwe Platzbecker
Journal: Blood
Blood (2019) 134 (Supplement_1): 673.
https://doi.org/10.1182/blood-2019-123854
Published: 2019
Journal Articles

Enasidenib Plus Azacitidine Significantly Improves Complete Remission and Overall Response Compared with Azacitidine Alone in Patients with Newly Diagnosed Acute Myeloid Leukemia (AML) with Isocitrate Dehydrogenase 2 ( IDH2 ) Mutations: Interim Phase II Results from an Ongoing, Randomized Study

Courtney D. DiNardo, MD MSc, Andre C. Schuh, MD, Eytan M. Stein, MD, Pau Montesinos Fernandez, MD PhD, Andrew Wei, MBBS, FRACP, FRCPA, PhD, Stephane De Botton, Amer M. Zeidan, MBBS, MHS, Amir T. Fathi, MD, Lynn Quek, MD PhD, Hagop M. Kantarjian, MD, Mark G. Frattini, MD, Frederik Lersch, RN, Jing Gong, PhD, Aleksandra Franovic, PhD, Kyle MacBeth, PhD, Paresh Vyas, MD PhD, Hartmut Döhner, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 643.
https://doi.org/10.1182/blood-2019-130362
Published: 2019
Journal Articles

Functional Impact of MacroH2A Histone Variants in Acute Myeloid Leukemia

Chen Jen Hsu, MSc, Tina M. Schnoeder, PhD, Patricia Arreba-Tutusaus, PhD, Maximilian Lassi, Raffaele Teperino, Stefan Dimitrov, Marcus Buschbeck, PhD, Florian H. Heidel, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1250.
https://doi.org/10.1182/blood-2019-122099
Published: 2019
Journal Articles

Eltrombopag Improves Erythroid Differentiation in a Human iPSC Model of Diamond Blackfan Anemia

Husam Qanash, MSc, Kaari Linask, Jeanette Beers, Keyvan Keyvanfar, Sara Young-Baird, Waleed Hakami, Richard H. Smith, Jizhong Zou, Andre Larochelle, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1214.
https://doi.org/10.1182/blood-2019-121822
Published: 2019
Journal Articles

Stanozolol and Danazol Have Different Effects on Hematopoiesis in Murine Model of Immune-Mediated Bone Marrow Failure

Hongmin Li, MD, Zhangbiao Long, MD, Bing Han, Zhao Wang, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2506.
https://doi.org/10.1182/blood-2019-126318
Published: 2019
Journal Articles

Development and Performance of Risk Stratification Models for AML Patients Utilizing ELN-2017 Guidelines and Additional Prognostic Factors: A SWOG Report

Era L Pogosova-Agadjanyan, BS, Anna Moseley, M.S., Megan Othus, PhD, Frederick R. Appelbaum, MD, Thomas R. Chauncey, MD PhD, I-Ming L. Chen, DVM, MS, Harry P. Erba, MD PhD, John E. Godwin, MD, Isaac C. Jenkins, MS, Min Fang, MD PhD, Mike Huynh, Kenneth J Kopecky, Alan F. List, MD, Jasmine Naru, PhD, Jerald P. Radich, MD, Emily Stevens, MD PhD, Brooke E Willborg, BS, Cheryl L. Willman, MD, Brent L Wood, MD PhD, Qing Zhang, Soheil Meshinchi, MD PhD, Derek Stirewalt, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2691.
https://doi.org/10.1182/blood-2019-124529
Published: 2019
Journal Articles

High Surface Expression of CD49d (VLA-4) and CD79b Correlates with Acalabrutinib Resistance in Patients with Chronic Lymphocytic Leukemia (CLL)

Elena Bibikova, Brian Law, Tracy Clevenger, PhD, Jean Cheung, MS, Gary De Jesus, Michael Gulrajani, Kyoko Yamaguchi, Phuong Do, Kathleen Burke, PhD, Graham Brock, PhD, Veerendra Munugalavadla, PhD, Melanie M. Frigault, PhD, John C. Byrd, MD, Richard R. Furman, MD, Jennifer R. Brown, MD PhD, Todd Covey
Journal: Blood
Blood (2019) 134 (Supplement_1): 2571.
https://doi.org/10.1182/blood-2019-128872
Published: 2019
Journal Articles

Evaluation of TIM-3-Positive LSCs Post Allo-SCT Is a Highly Sensitive Strategy to Predict AML Relapses

Teppei Sakoda, MD, Yoshikane Kikushige, MD PhD, Takuya Harada, MD, Hidetoshi Irifune, MD, Masayasu Hayashi, MD PhD, Goichi Yoshimoto, MD PhD, Toshihiro Miyamoto, MD PhD, Koichi Akashi, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2702.
https://doi.org/10.1182/blood-2019-127779
Published: 2019