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Journal Articles

Impaired condensin complex and Aurora B kinase underlie mitotic and chromosomal defects in hyperdiploid B-cell ALL

Blood (2020) 136 (3): 313–327.

https://doi.org/10.1182/blood.2019002538

Published: 2020

Includes: Supplemental data

Journal Articles

Preclinical Activity of the MPS1 Inhibitor S81694 in Acute Lymphoblastic Leukemia (ALL)

Anna Kaci, PhD, Emilie Adiceam, Melanie Dupont, Marine Garrido, Jeannig Berrou, Hanane Djamai, Andre Baruchel, Mike Burbridge, Claude Gardin, Herve Dombret, MD PhD, Thorsten Braun, MD

Blood (2019) 134 (Supplement_1): 2631.

https://doi.org/10.1182/blood-2019-125641

Published: 2019

Journal Articles

Investigation of Cell-Contact Dependent Alterations in Immune Synapse Formation between T Cells and BCP-ALL Cells

Britta Wenske, PhD, Lothar Marischen, PhD, Julia Welzenbach, André Heimbach, PhD, Per Hoffmann, PhD, Selim Corbacioglu, MD, David A Williams, MD, Anja Troeger, MD

Blood (2019) 134 (Supplement_1): 2754.

https://doi.org/10.1182/blood-2019-128835

Published: 2019

Journal Articles

DNMT3A with Leukemia-Associated Mutations Directs Sensitivity to DNA Damage at Replication Forks

Kartika Venugopal, MS, Daniil E Shabashvili, PhD, Jianping Li, MD, Luisa M Posada, Richard Lynn Bennett, PhD, Yang Feng, MS, Daphne Dupere Richer, PhD, Alberto Riva, PhD, Santhi Pondugula, PhD, Jonathan E. Bird, PhD, Jonathan D. Licht, MD, Olga A Guryanova, MD PhD

Blood (2019) 134 (Supplement_1): 535.

https://doi.org/10.1182/blood-2019-128213

Published: 2019

Journal Articles

Anticancer Activity of a Highly Potent Small Molecule Tubulin Polymerization Inhibitor, AB8939

Martine Humbert, PhD, Armelle Goubard, PhD, Colin Mansfield, PhD, Olivier Hermine, MD PhD, Patrice Dubreuil, PhD, The AB8939 Study Group

Blood (2019) 134 (Supplement_1): 2075.

https://doi.org/10.1182/blood-2019-122540

Published: 2019

Journal Articles

Lysosomal Activation Is Required for Priming of Quiescent Hematopoietic Stem Cells

Tasleem Arif, PhD, Raymond Liang, PhD, Maio Lin, Msc, Svetlana Kalmikova, Msc, Artem Kasianov, PhD, Dmitri Papatsenko, PhD, Saghi Ghaffari, PhD MD

Blood (2019) 134 (Supplement_1): 722.

https://doi.org/10.1182/blood-2019-131934

Published: 2019

Journal Articles

KIFC1 Mediates Centrosome Clustering Prior to Proplatelet Formation from Megakaryocytes

Adrian R. Wilkie, PhD, Leila J. Noetzli, PhD, Genevieve Couldwell, Anthony R. Sciaudone, Anjana Ray, PhD, Kellie R. Machlus, PhD, Joseph E. Italiano, Jr., BS, PhD

Blood (2019) 134 (Supplement_1): 721.

https://doi.org/10.1182/blood-2019-130803

Published: 2019

Journal Articles

Formin Links Erythroid Cytoskeleton to Organelle Clearance through Escrt-III Complex during Reticulocyte Maturation

Yijie Liu, PhD, Haiyan Bao, MD, Yang Mei, PhD, Xu Han, PhD, Peng Ji, MD PhD

Blood (2019) 134 (Supplement_1): 151.

https://doi.org/10.1182/blood-2019-125157

Published: 2019

Journal Articles

The Condensin II Subunit, NcapH2, Is Required for Proper Embryonic Erythroid Terminal Maturation and Embryonic Viability in a Primary Mouse Model

Zachary C. Murphy, PhD, Michael Getman, MS, Laurie A. Steiner, MD

Blood (2019) 134 (Supplement_1): 153.

https://doi.org/10.1182/blood-2019-127353

Published: 2019

Journal Articles

Activated but Not Quiescent Hematopoietic Stem Cells Rely Readily on Glycolysis As Their Main Source of Energy

Tasleem Arif, PhD, Raymond Liang, PhD, Maio Lin, Msc, Svetlana Kalmikova, Msc, Artem Kasianov, PhD, Vijay Menon, PhD, Dmitri Papatsenko, PhD, Saghi Ghaffari, PhD MD

Blood (2019) 134 (Supplement_1): 271.

https://doi.org/10.1182/blood-2019-129099

Published: 2019

Journal Articles

Leukemogenic Functions of Mutant ASXL1 Are Regulated By CDK-Mediated Phosphorylation

Shuhei Asada, MD PhD, Susumu Goyama, MD PhD, Reina Takeda, MD, Keita Yamamoto, MD, Hiroko Kozuka-Hata, PhD, Masaaki Oyama, PhD, Daichi Inoue, MD PhD, Hiroaki Honda, MD PhD, Toshio Kitamura, MD PhD

Blood (2019) 134 (Supplement_1): 731.

https://doi.org/10.1182/blood-2019-125959

Published: 2019

Journal Articles

DIS3 Mutation in RUNX1-Mutated AML1 Confers a Highly Dismal Prognosis in AML By Repressing Sister Chromatid Cohesion

Christophe Desterke, PhD, Annelise Bennaceur-Griscelli, MD PhD, Ali G Turhan, MD PhD

Blood (2019) 134 (Supplement_1): 1454.

https://doi.org/10.1182/blood-2019-123352

Published: 2019

Journal Articles

Suv39h1 Represses the Progression of MLL -Rearranged Myeloid Leukemia Via Hoxb13

Yajing Chu, PhD, Yangpeng Chen, Huidong Guo, PhD, Mengke Li, Jun Shi, MD, Tao Cheng, MD, Feng-Chun Yang, MD PhD, Mingjiang Xu, MD PhD, Weiping Yuan, PhDMD

Blood (2018) 132 (Supplement 1): 3878.

https://doi.org/10.1182/blood-2018-99-113732

Published: 2018

Journal Articles

Hematopoietic Stem and Progenitor Cell Proliferation and Differentiation Requires the Trithorax Protein Ash2l In Vivo

Nicolas Chatain, PhD, Juliane Lüscher-Firzlaff, Chao-Chung Kuo, Agnieszka Bochyńska, Andrea Ullius, Bernd Denecke, Ivan Costa, Steffen Koschmieder, MD, Bernhard Lüscher

Blood (2018) 132 (Supplement 1): 2566.

https://doi.org/10.1182/blood-2018-99-115950

Published: 2018

Journal Articles

Loss of miR-199b Impairs Active Cycling of Hematopoietic Stem Cells during Steady-State Hematopoiesis

Aldona A Karaczyn, Edward Jachimowicz, Jaspreet S Kohli, Pradeep Sathyanarayana

Blood (2018) 132 (Supplement 1): 1283.

https://doi.org/10.1182/blood-2018-99-116381

Published: 2018

Journal Articles

PDK1 Regulates HSCs Via the Foxo Pathway during Murine Fetal Liver Hematopoiesis

Weiping Yuan, PhDMD

Blood (2017) 130 (Supplement 1): 1135.

https://doi.org/10.1182/blood.V130.Suppl_1.1135.1135

Published: 2017

Journal Articles

Differential Phosphoproteomics Provides New Insights into Role of DYRK1A in Lymphopoiesis

Rahul S. Bhansali, Malini Rammohan, BS, Ji Heon Paul Lee, MD PhD, John D. Crispino, PhD

Blood (2017) 130 (Supplement 1): 1152.

https://doi.org/10.1182/blood.V130.Suppl_1.1152.1152

Published: 2017

Journal Articles

Preclinical and Early Phase 1 Clinical Data of AZD2811 Nanoparticle in AML, an Aurora B Kinase Inhibitor

Wolfram Brugger, MDPhD, Susan Ashton, Carrie A. Adelman, Nicolas Floc'h, Paula Taylor, Maureen Hattersley, PhD, Shenghua Wen, Kimberly Maratea, Philip Overend, Steven Fox, Julie Charlton, Simon T Barry, Donald Strickland, MD, Suzanne Jones, PharmD, Howard A. Burris, MD, Carol Greenlees, Alexander MacDonald, J. Elizabeth Pease, PhD, William Donnellan

Blood (2017) 130 (Supplement 1): 1368.

https://doi.org/10.1182/blood.V130.Suppl_1.1368.1368

Published: 2017

Journal Articles

Dot1l Reverses the Abnormal Self-Renewal Conferred on HSPCs through Cohesin Haploinsufficiency By Diminishing Expression of Hoxa7 and Hoxa9

Joseph B Fisher, PhD, Cary Stelloh, Emily Kristine Phillips, BS, Katelyn Heimbruch, BS, Alison E Meyer, PhD, Kirthi Pulakanti, Maureen McNulty, BS, Aaron D Viny, MDMS, Ross L. Levine, MD, John D. Crispino, PhD, Sridhar Rao, MD PhD

Blood (2017) 130 (Supplement 1): 246.

https://doi.org/10.1182/blood.V130.Suppl_1.246.246

Published: 2017

Journal Articles

Genetic Heterogeneity of t(8;21)(q22;q22.1) Acute Myeloid Leukemia Revealed By High-Throughput Targeted Sequencing

Blood (2017) 130 (Supplement 1): 2688.

https://doi.org/10.1182/blood.V130.Suppl_1.2688.2688

Published: 2017

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Impaired condensin complex and Aurora B kinase underlie mitotic and chromosomal defects in hyperdiploid B-cell ALL

Preclinical Activity of the MPS1 Inhibitor S81694 in Acute Lymphoblastic Leukemia (ALL)

Investigation of Cell-Contact Dependent Alterations in Immune Synapse Formation between T Cells and BCP-ALL Cells

DNMT3A with Leukemia-Associated Mutations Directs Sensitivity to DNA Damage at Replication Forks

Anticancer Activity of a Highly Potent Small Molecule Tubulin Polymerization Inhibitor, AB8939

Lysosomal Activation Is Required for Priming of Quiescent Hematopoietic Stem Cells

KIFC1 Mediates Centrosome Clustering Prior to Proplatelet Formation from Megakaryocytes

Formin Links Erythroid Cytoskeleton to Organelle Clearance through Escrt-III Complex during Reticulocyte Maturation

The Condensin II Subunit, NcapH2, Is Required for Proper Embryonic Erythroid Terminal Maturation and Embryonic Viability in a Primary Mouse Model

Activated but Not Quiescent Hematopoietic Stem Cells Rely Readily on Glycolysis As Their Main Source of Energy

Leukemogenic Functions of Mutant ASXL1 Are Regulated By CDK-Mediated Phosphorylation

DIS3 Mutation in RUNX1-Mutated AML1 Confers a Highly Dismal Prognosis in AML By Repressing Sister Chromatid Cohesion

Suv39h1 Represses the Progression of MLL -Rearranged Myeloid Leukemia Via Hoxb13

Hematopoietic Stem and Progenitor Cell Proliferation and Differentiation Requires the Trithorax Protein Ash2l In Vivo

Loss of miR-199b Impairs Active Cycling of Hematopoietic Stem Cells during Steady-State Hematopoiesis

PDK1 Regulates HSCs Via the Foxo Pathway during Murine Fetal Liver Hematopoiesis

Differential Phosphoproteomics Provides New Insights into Role of DYRK1A in Lymphopoiesis

Preclinical and Early Phase 1 Clinical Data of AZD2811 Nanoparticle in AML, an Aurora B Kinase Inhibitor

Dot1l Reverses the Abnormal Self-Renewal Conferred on HSPCs through Cohesin Haploinsufficiency By Diminishing Expression of Hoxa7 and Hoxa9

Genetic Heterogeneity of t(8;21)(q22;q22.1) Acute Myeloid Leukemia Revealed By High-Throughput Targeted Sequencing

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