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Journal Articles

Influence of Bone Marrow Stromal and Leukemic Cells on Cytarabine Chemo-Toxicity in Acute Myeloid Leukemia (AML)

Free
Liana E Gynn, BSc, Elizabeth Anderson, PhD, Gareth M Robinson, PhD, Sarah Anne Wexler, MBBS, MRCP, FRCPath, Gillian Upstill-Goddard, Christine Cox, Rhys Gareth Morgan, PhD, Jennifer E May, PhD BSc
Journal: Blood
Blood (2019) 134 (Supplement_1): 2492.
https://doi.org/10.1182/blood-2019-122891
Published: 2019
Journal Articles

Dysregulation of Hemostatic Biomarkers, Inflammatory Biomarkers, and Alteration of Cellular Indices As Predictors of Adverse Outcomes in Pulmonary Embolism Patients

Free
Iman Darwish, Yevgeniy Brailovsky, DO, Amir Darki, MD MSc, Debra Hoppensteadt, PhD, Brett Slajus, Emily Bontekoe, Frank De Stefano, Jawed Fareed, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2408.
https://doi.org/10.1182/blood-2019-126876
Published: 2019
Journal Articles

Changes in Tumor Immune Micro-Environment in Diffuse Large B-Cell Lymphoma (DLBCL): A Comparative Study of Relapsed Versus Diagnostic DLBCL

Free
Raoul Santiago, MDMSc, Nathalie Johnson, MD, Svetlana Dmitrienko, MD PhD, Andreas Papadakis, PhD, Naciba Benlimame, PhD, François Mercier, MD, Koren Kathleen Mann, PhD, Sarit Assouline, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3968.
https://doi.org/10.1182/blood-2019-122207
Published: 2019
Journal Articles

Transcriptome Sequencing Demonstrates Unique Signature Associated with Durable Clinical Response to DC/AML Fusion Vaccine

Free
Jessica Liegel, MD, Manoj Bhasin, PhD, German A. Pihan, MD, Dina Stroopinsky, PhD, Beena Thomas, PhD, Shreya Sindhu, Haider Ghiasuddin, Emma Logan, Adam Morin, Marzia Capelletti, PhD MMSc, Shira Orr, PhD, Myrna Nahas, MD, Matthew Weinstock, MD, Maryam Rahimian, MD, Lina Bisharat, Shufen Meng, MD, Richard M. Stone, MD, Donald Kufe, MD, David E. Avigan, MD, Jacalyn Rosenblatt, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3832.
https://doi.org/10.1182/blood-2019-129451
Published: 2019
Journal Articles

Mapping the Road of Gvhd and GVT: A Longitudinal Study of Immune-Transcriptome Signatures As Novel Approach to Solve Post-Allogeneic Hematopoietic Cell Transplantation Dilemmas

Free
Merav Bar, MD, Alice Woo, Mohammed Toufiq, Sabri Boughorbel, Darawan Rinchai, Mohammed Elanbari, Valentina Mattei, Rebecca Mathew, Irene Cavattoni, MD, Sabine Forer, Marco Zecca, Patrizia Comoli, Giovanni Grillo, MD, Catherine Cole, Chiara Cugno, MD, Sara Tomei, PhD, Damien Chaussabel, Sara Deola
Journal: Blood
Blood (2019) 134 (Supplement_1): 4550.
https://doi.org/10.1182/blood-2019-122884
Published: 2019
Journal Articles

Lack of Significant Differences in Somatic Alterations between MGUS, SMM and Symptomatic Multiple Myeloma: A Result from Comprehensive Genomic Profiling Study

Free
Anil Aktas Samur, PhD, Mariateresa Fulciniti, PhD, Raphael Szalat, Jill Corre, PharmD, PhD, Niccolo Bolli, MD PhD, Philippe Moreau, MD, Michel Attal, MD PhD, Kenneth C. Anderson, MD, Giovanni Parmigiani, PhD, Hervé Avet-Loiseau, MD PhD, Mehmet Kemal Samur, PhD, Nikhil C. Munshi, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3089.
https://doi.org/10.1182/blood-2019-128570
Published: 2019
Journal Articles

HDAC8 Maintain Cytoskeleton Integrity Via Homologous Recombination and Represent a Novel Therapeutic Target in Multiple Myeloma

Free
Zuzana Chyra, PhD, Maria Gkotzamanidou, MD PhD, Masood A. Shammas, PhD, Vassilis L. Souliotis, PhD, Yan Xu, MD, Mehmet K. Samur, PhD, Aaron B. Beeler, PhD, Roman Hajek, MD, Mariateresa Fulciniti, PhD, Nikhil C. Munshi, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4385.
https://doi.org/10.1182/blood-2019-130700
Published: 2019
Journal Articles

Novel Genetic Mechanism of Venetoclax Resistance in AML: BAX Deletion

Free
Farid Ahmed, MSc, PhD, Omar Abdullah Allehyani, BSc, MSc, Mansour Alfayez, MDMS, Hans-Jurgen Schulten, MSc, PhD, Heba Alkhattabi, MSc, PhD, Adeel G A Chaudhary, MSc, PhD, Mohammed H Alqahtani, MSc, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5057.
https://doi.org/10.1182/blood-2019-131637
Published: 2019
Journal Articles

Response to First-Line Treatment in Patients with N/K T-Cell Lymphoma. Experience of a Third Level Mexican Institute

Free
Katheryn Betsabe Garzón, MD, Silvia Rivas-Vera, MD, Brenda L. Acosta-Maldonado, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5286.
https://doi.org/10.1182/blood-2019-129887
Published: 2019
Journal Articles

Storage-Induced Micro-Erythrocytes Are Rapidly Cleared from Recipient Circulation and Predict Transfusion Recovery

Free
Camille Roussel, MD PhD, Alexandre Morel, MD, Michaël Dussiot, PhD, Mickael MARIN, Martin Colard, MD, Aurélie Fricot, Anaïs Martinez, Charlotte Chambrion, Benoît Henry, MD PhD, Geoffroy Volle, Mallorie Depond, Safi Dokmak, MD, Francois Paye, MD, Alain Sauvanet, MD, Caroline Le Van Kim, PhD, Yves Colin Aronovicz, PhD, Steven L. Spitalnik, MD, Papa Alioune Ndour, PhD, Eldad A. Hod, MD, Olivier Hermine, MD PhD, Pierre Buffet, MD PhD, Pascal Amireault, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 717.
https://doi.org/10.1182/blood-2019-128161
Published: 2019
Journal Articles

Single-Cell Analysis Based Dissection of Clonality in Myelofibrosis

Free
Elena Mylonas, Kenichi Yoshida, MD PhD, Mareike Frick, Kaja Hoyer, Friederike Christen, Jaspal Kaeda, PhD FRCPath, Matthias Obenaus, Daniel Nörenberg, MD, Cornelius Hennch, Willy Chan, Yotaro Ochi, MD, Yuichi Shiraishi, Yusuke Shiozawa, MD PhD, Thorsten Zenz, MD, Christopher C. Oakes, PhD, Birgit Sawitzki, Michaela Schwarz, MD, Lars Bullinger, Philipp Le Coutre, MD, Matthew John Jerome Rose-Zerilli, Seishi Ogawa, MD PhD, Frederik Damm, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 469.
https://doi.org/10.1182/blood-2019-123367
Published: 2019
Journal Articles

Final Results of Phase 2 Clinical Trial of LCL161, a Novel Oral SMAC Mimetic/IAP Antagonist, for Patients with Intermediate to High Risk Myelofibrosis

Free
Naveen Pemmaraju, MD, Bing Z Carter, PhD, Hagop M. Kantarjian, MD, Jorge E. Cortes, MD, Prithviraj Bose, MD, Tapan M. Kadia, MD, Guillermo Garcia-Manero, MD, Carlos E. Bueso-Ramos, MD PhD, Courtney D. DiNardo, MD MSc, Sharon Bledsoe, Naval G. Daver, MD, Uday Popat, MD, Marina Y Konopleva, MD PhD, Maro Ohanian, DO, Sherry A. Pierce, BSN, BA, Lingsha Zhou, Zeev E. Estrov, MD, Gautam M. Borthakur, MD, Po Yee Mak, Nitin Jain, MD, Elias Jabbour, MD, Srdan Verstovsek, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 555.
https://doi.org/10.1182/blood-2019-130046
Published: 2019
Journal Articles

Increased Platelet Force Is Associated with Decreased Bleeding Severity in Pediatric Immune Thrombocytopenia

Free
Oluwamayokun T. Oshinowo, BS, Renee Copeland, BS, Christina Caruso, MD, Meredith E. Fay, BS, Traci Leong, PhD, Carolyn M. Bennett, MDMSc, Wilbur A. Lam, MD PhD, David R. Myers, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1096.
https://doi.org/10.1182/blood-2019-129573
Published: 2019
Journal Articles

The Immune Micro-Environment in Diffuse Large B Cell Lymphoma Is Characterised By an Immunosuppressive Shift in T Cell Subsets

Free
Edward Truelove, MBBS, BSc, MRCP, FRCPath, Frances Seymour, MRCP, BSc, MBBS, Joseph G Taylor, MBBS, BSc, Mariarita Calaminici, Andrew James Clear, BSc, John G. Gribben, MD DSc
Journal: Blood
Blood (2019) 134 (Supplement_1): 5240.
https://doi.org/10.1182/blood-2019-130712
Published: 2019
Journal Articles

Genetic Mutation in Cytopenic Patients: Distinctive Genomic Profile between Preclinical Vs. Clinical Myelodysplastic Syndrome

Free
Kritanan Songserm, MD, Amornchai Suksusut, Sunisa Kongkiatkamon, Kitsada Wudhikarn, MD, Chinnachote Teerapakpinyo, Chantiya Chanswangpuwana, Sirorat Kobbuaklee, Shanop Shuangshoti, Udomsak Bunworasate, MD, Ponlapat Rojnuckarin, MD PhD, Chantana Polprasert, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5429.
https://doi.org/10.1182/blood-2019-128037
Published: 2019
Journal Articles

MCL-1 Inhibitor-Induced Killing of Multiple Myeloma Is Modulated By the Relative Level of Expression of Pro-Survival Members of the BCL-2 Family and the Proto-Oncogene MYC

Free
Andrew Spencer, DM, Tiffany Khong, BSc, PhD, Maoshan Chenn, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1825.
https://doi.org/10.1182/blood-2019-127843
Published: 2019
Journal Articles

Deciphering Molecular Heterogeneity in Pediatric AML Using a Cancer Vs Normal Transcriptomic Approach

Free
Barbara Depreter, PhD PharmD, Mattias Hofmans, MD, Eva Terras, Anne Uyttebroeck, MD, An Van Damme, MD, Alina Ferster, MD, Jutte Van der Werff Ten Bosch, MD, Marie-Françoise Dresse, MD PhD, Karl Vandepoele, PhD, Barbara De Moerloose, MD PhD, Jan Philippé, MD PhD, Tim Lammens, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1457.
https://doi.org/10.1182/blood-2019-125538
Published: 2019
Journal Articles

Genetics of Monosomy 7 and Del(7q) in MDS Informs Potential Therapeutic Targets

Free
Cassandra M Kerr, MS, Vera Adema, PhD, Wencke Walter, PhD, Stephan Hutter, PhD, Christina A. Snider, BA, Yasunobu Nagata, MD PhD, Manja Meggendorfer, PhD, Claudia Haferlach, MD, Valeria Visconte, PhD, Mikkael A. Sekeres, MD MS, Thomas Laframboise, PhD, Torsten Haferlach, MD, Jaroslaw P. Maciejewski, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1703.
https://doi.org/10.1182/blood-2019-126866
Published: 2019
Journal Articles

Comparative Somatic Mutational Profiling of CD34+ Hematopoietic Precursors (HSC) and Circulating Endothelial Cells (CEC) in Patients with Primary Myelofibrosis (PMF)

Free
Mirko Farina, MD, Simona Bernardi, PhD, Nicola Polverelli, Camilla Zanaglio, PhD, Michele Malagola, MD, Federica Re, Federica Cattina, MD PhD, Mariella D'Adda, MD, Giuseppe Rossi, Tatiana Zollner, MD, Andrew Dunbar, MD, Ross L. Levine, MD, Domenico Russo, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1684.
https://doi.org/10.1182/blood-2019-127451
Published: 2019
Journal Articles

Targeting Nicotinamide Adenine Dinucleotide (NAD) Glycohydrase Activity of CD38 Exerts Anti-Myeloma Effect Accompanying Intracellular NAD Elevation

Free
Saki Kushima, Takayuki Sasano, Masao Matsuoka, MD PhD, Hiroyuki Hata, MD PhD, Yawara Kawano, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1810.
https://doi.org/10.1182/blood-2019-123624
Published: 2019