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Journal Articles

Association between Inflammatory Markers and Abnormal Neurological, Neurocognitive and Magnetic Resonance Imaging (MRI) Findings in Children with Sickle Cell Anemia in Uganda

Free
Amelia Boehme, PhD MSPH, Adiba Ashrafi, MS, Richard Idro, MMED, PhD, Paul Bangirana, MS, PhD, Deogratias Munube, MD, Robert Opoka, MMED, Philip Kasirye, MMED, Margaret T. Lee, MD, Nancy S. Green, MD, Mady Hornig, MA, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2300.
https://doi.org/10.1182/blood-2019-131560
Published: 2019
Journal Articles

A Rise in Plasma Coagulability during the First 3 Months Following Provoked Venous Thromboembolism Is Associated with the Development of Post-Thrombotic Syndrome in Children and Young Adults: Analysis of the Kids-DOTT Multicenter Trial-Derived Biobank

Free
Marisol Betensky, MDMPH, Ernest Amankwah, PhD, Stephanie Brandal, Allen Everett, MD, Neil A Goldenberg, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2424.
https://doi.org/10.1182/blood-2019-131821
Published: 2019
Journal Articles

Altered Megakaryocytes Are Associated with Development of Pulmonary Fibrosis in Mice Carrying the Hypomorphic Gata1 low Mutation

Free
Barbara Bacci, PhD, Francesca Gobbo, Mariana Roccaro, Angelo Peli, PhD, Maria Zingariello, PhD, Fabrizio Martelli, PhD, Paola Verachi, Claudio Bardelli, PhD, Maria Mazzarini, Giuseppe Sarli, PhD, Anna Rita Migliaccio, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2336.
https://doi.org/10.1182/blood-2019-123994
Published: 2019
Journal Articles

A Novel Assay of Neutrophil Extracellular Traps (NETs) Formation Independently Predicts DIC and Identifies the Rationale for Anti-IL-8 Therapies

Free
Simon Timothy Abrams, PhD BSc, Ben Morton, MBChB, MD, Yasir Alhamdi, MBChB, PhD, Mohmad Alsabani, Zhenxing Cheng, Steven Lane, PhD, Ingeborg Welters, PhD, Guozheng Wang, MD PhD, Cheng-Hock Toh, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 440.
https://doi.org/10.1182/blood-2019-128493
Published: 2019
Journal Articles

CRISPR/Cas9 Mediated ELANE Knock-out Restores Survival and Granulocytic Differentiation of HL60 Cells Expressing Mutant Neutrophil Elastase: Is Neutrophil Elastase a Dispensible Granulocyte Protease?

Free
Vahagn Makaryan, MD, Isabella N. Archibald, Merideth L. Kelley, MS, Breanna Fletcher, BSc, David C. Dale, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 435.
https://doi.org/10.1182/blood-2019-124988
Published: 2019
Journal Articles

Vitamin D and Inflammatory Markers in Children with Sickle Cell Disease

Free
Margaret T. Lee, MD, Adiba Ashrafi, MS, Mady Hornig, MA, MD, Amelia Boehme, PhD MSPH, Nancy S. Green, MD, Gary M. Brittenham, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2312.
https://doi.org/10.1182/blood-2019-129771
Published: 2019
Journal Articles

Hispanic Ethnicity Is Associated with Low End of Induction Absolute Lymphocyte Count in Pediatric Acute Lymphoblastic Leukemia

Free
Adriana Saavedra-Simmons, Wanda LeJeune, M.Sc., Geraldine Aubert, PhD, Kellen Gandy, PhD, Lisa R. Hartman, MD, Jill Hartley, MSN, RN, Rodrigo Erana, MD, Juan C. Bernini, MD, Olga Taylor, MPH, Philip J. Lupo, PhD MPH, Michael E. Scheurer, PhD MPH, Karen R. Rabin, MD PhD, Maria Monica Monica Gramatges, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5197.
https://doi.org/10.1182/blood-2019-131222
Published: 2019
Journal Articles

Preliminary Report of MANIFEST, a Phase 2 Study of CPI-0610, a Bromodomain and Extraterminal Domain Inhibitor (BETi), in Combination with Ruxolitinib, in JAK Inhibitor (JAKi) Treatment Naïve Myelofibrosis Patients

Free
Claire N Harrison, Professor, Andrea Patriarca, MD, John Mascarenhas, MD, Marina Kremyanskaya, Ronald Hoffman, MD, Gary J. Schiller, MD, Brian Leber, MD, Timothy Devos, MD PhD, Sujan Kabir, MD, Adrian Senderowicz, MD, Jennifer Mertz, PhD, Patrick Trojer, PhD, James Shao, MS, Vikas Gupta, MD FRCP, FRCPath
Journal: Blood
Blood (2019) 134 (Supplement_1): 4164.
https://doi.org/10.1182/blood-2019-128211
Published: 2019
Journal Articles

Cyclic-AMP Is an Actionable Novel Regulator of PD-L1 Expression in Untransformed Lymphocytes and Diffuse Large B Cell Lymphomas

Free
Binu Sasi, PhD, Zhijun Qiu, PhD, Shoulei Jiang, PhD, An-Ping Lin, MD, Ricardo Aguiar, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3962.
https://doi.org/10.1182/blood-2019-123155
Published: 2019
Journal Articles

Correlative Analyses of Patient and Clinical Characteristics Associated with Efficacy in Tisagenlecleucel-Treated Relapsed/Refractory Diffuse Large B-Cell Lymphoma Patients in the Juliet Trial

Free
Jason R. Westin, MD, Constantine S. Tam, MBBS, MD, Peter Borchmann, MD, Ulrich Jaeger, MD, Joseph P. McGuirk, DO, Harald Holte, MD PhD, Edmund K. Waller, PhDMD, Samantha Jaglowski, MDMPH, Michael R. Bishop, MD, Charalambos Andreadis, MD MSCE, Stephen Ronan Foley, MD FRCPC, Isabelle Fleury, MD, P Joy Ho, MBBS(Syd) DPhil(Oxon) FRACP FRCPA FFSc(RCPA), Stephan Mielke, MD, Takanori Teshima, MD, Stephen J Schuster, MD, Veronika Bachanova, MD PhD, Richard T. Maziarz, MD, Koen Van Besien, MD PhD, Koji Izutsu, MD PhD, Marie Jose Kersten, MD PhD, John M. Magenau, MD, Nina D. Wagner-Johnston, MD, Koji Kato, MD PhD, Paolo Corradini, Xia Han, MS, Ranjan Tiwari, MSc, Sergei Agoulnik, PhD, Lamis K. Eldjerou, MD, Lida Bubuteishvili Pacaud, MD, Gilles A. Salles, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4103.
https://doi.org/10.1182/blood-2019-129107
Published: 2019
Journal Articles

Allogeneic Cord Blood Regulatory T Cells Can Prevent Graft Vs. Host Disease and Preserve Graft Vs Leukemia Effect: Update on Phase I/II Clinical Trial

Free
Ke Zeng, MD PhD, Hongbing Ma, MD PhD, Uday Popat, MD, Yago Nieto, MD PhD, Stefan O. Ciurea, MD, Amanda L. Olson, MD, Mi-Ae Lyu, PhD, Meixian Huang, Mitsutaka Nishimoto, MD PhD, Muzaffar H. Qazilbash, MD, Jennifer D Ramos, RN, Elizabeth J. Shpall, MD, Richard E. Champlin, MD, Simrit Parmar, MBBS, Borje S Andersson, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4547.
https://doi.org/10.1182/blood-2019-127726
Published: 2019
Journal Articles

A Novel Proteomic Profiling of the Bone Marrow Microenvironment Reveals Elevated Levels of the Chemokine CCL23 Isoforms in Acute Myeloid Leukemia

Free
Haydar Celik, PhD, Katherine E. Lindblad, Bogdan Popescu, Giovanna Fantoni, Gege Gui, Janet Valdez, Meghali Goswami, Christin Destefano, MD, Catherine E. Lai, MD, Angélique Biancotto, Julián Candia, Foo Cheung, Julie Thompson, Jack Y. Ghannam, Gauthaman Sukumar, Richard H. Smith, Clifton L. Dalgard, PhD, Andre Larochelle, MD PhD, Laura Dillon, Christopher S. Hourigan, MDDPhil
Journal: Blood
Blood (2019) 134 (Supplement_1): 2709.
https://doi.org/10.1182/blood-2019-122121
Published: 2019
Journal Articles

Diffuse Large B Cell Lymphoma (DLBCL)-Released NM23-H1 Promotes Monocyte Survival and Inflammatory Cytokine Release: A Mechanistic Link between the Dual Impacts of NM23-H1 Expression and Reduced Lymphocyte:Monocyte Ratio in DLBCL Prognosis

Free
Sandro Trova, PhD, Maiss Al-Amere, PhD, Jayna J Mistry, BSc, Zuhal Eraslan, Bader Alhazmi, Joy Harris-Folb, Alessandro Di Maio, Mark T Drayson, MB ChB, PhD FRCPath, Christopher M Bunce, BSc, Stuart A Rushworth, PhD, Farhat Latif Khanim, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2803.
https://doi.org/10.1182/blood-2019-130889
Published: 2019
Journal Articles

Gene Expression and Cytokine Analyses Identify Markers of Progression from CLL-like Monoclonal B-Cell Lymphocytosis to Chronic Lymphocytic Leukemia

Free
Gonzalo Blanco, PhD, Anna Puiggros, PhD, Barbara Sherry, PhD, Lara Nonell, Eulalia Puigdecanet, Pui Yan Chiu, Yasmine Kieso, MSCR, Gerardo Ferrer, PhD, Magdalena Arnal, María Rodríguez-Rivera, Eva Gimeno, MD PhD, Eugenia Abella, Kanti R Rai, MD, Pau Abrisqueta, MD PhD, Xavier Calvo, MD PhD, Francesc Bosch, MD PhD, Ana Ferrer, MD PhD, Nicholas Chiorazzi, MD, Blanca Espinet, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3027.
https://doi.org/10.1182/blood-2019-122038
Published: 2019
Journal Articles

Development of HHV-6-Specific Immunity after Cord Blood Transplantation in Adults Depends on Reconstitution of Thymopoiesis and Regeneration of CD4 + T Cells

Free
Natalia M Tijaro-Ovalle, MD, Shuli Li, PhD, Zachariah Defilipp, MD, Ioannis Politikos, MD, Robin M. Joyce, MD, Philippe Armand, MD PhD, Vincent T. Ho, John Koreth, MBBS, DPhil, Sarah Nikiforow, MD PhD, Edwin P. Alyea, III, MD, David E. Avigan, MD, Jacalyn Rosenblatt, MD, Jami Brown, MS, Steven McAfee, MD, Bimalangshu Dey, MD, Areej El-Jawahri, MD, Thomas Spitzer, MD, Yi-Bin Chen, Robert J. Soiffer, MD, Joseph H. Antin, MD, Karen K. Ballen, MD, Corey S. Cutler, MD MPH, FRCPC, Jerome Ritz, MD, Vassiliki A Boussiotis, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3275.
https://doi.org/10.1182/blood-2019-129154
Published: 2019
Journal Articles

A Biomarker Signature to Predict Complete Response to Itacitinib and Corticosteroids in Acute Graft Versus Host Disease

Free
Michael A. Pratta, MSc, Hao Liu, PhD, Sherry Owens, PhD, Ying Yan, PhD, Michael C. Arbushites, Michael D. Howell, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3279.
https://doi.org/10.1182/blood-2019-124069
Published: 2019
Journal Articles

Superior Efficacy of CAR-T Cells Using Marrow-Infiltrating Lymphocytes (MILs TM ) As Compared to Peripheral Blood Lymphocytes (PBLs)

Free
Eric R. Lutz, PhD, Srikanta Jana, PhD, Lakshmi Rudraraju, MS, Elizabeth DeOliveira, Jing Zhou, Sean Mackay, Ivan M. Borrello, MD, Kimberly Noonan, PhD MPH
Journal: Blood
Blood (2019) 134 (Supplement_1): 4437.
https://doi.org/10.1182/blood-2019-130629
Published: 2019
Journal Articles

Stratification of Responders and Non-Responders in the Reach-1 Trial Based on Serum Proteomic Analysis

Free
Sherry Owens, PhD, Michael A. Pratta, MSc, Hao Liu, PhD, Michael C. Arbushites, Chuan Tian, PhD, Michael D. Howell, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4531.
https://doi.org/10.1182/blood-2019-127147
Published: 2019
Journal Articles

The Influence of FLT3-ITD Mutation on Baseline Levels of Selected Cytokines and Soluble Adhesion Molecules in Acute Myeloid Leukemia with Mutated NPM-1

Free
Tomas Kupsa, MD PhD, Jan M Horacek, MD PhD, Ladislav Jebavy, MD PhD, Pavel Zak, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5111.
https://doi.org/10.1182/blood-2019-126433
Published: 2019
Journal Articles

Markers of Initial and Long-Term Responses to Idecabtagene Vicleucel (Ide-Cel; bb2121) in the CRB-401 Study in Relapsed/Refractory Multiple Myeloma

Free
Ethan G. Thompson, PhD, Yue Jiang, PhD, Timothy B. Campbell, MD PhD, Jaymes Fuller, PhD, Shari Kaiser, PhD, Afshin Mashadi-Hossein, MSc, Julie Rytlewski, PhD, Nathan Martin, PhD, Olivia Finney, PhD, Katja Kleinsteuber, PhD, Eric Alonzo, PhD, Chetanya Pandya, PhD, Amit Agarwal, MD PhD, Kristen Hege, Noopur S. Raje, MD, Nikhil C. Munshi, MD, Ronald J. Hause, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4328.
https://doi.org/10.1182/blood-2019-124998
Published: 2019